메뉴 건너뛰기




Volumn 32, Issue 1, 2015, Pages 275-285

Semi-interpenetrating network (Sipn) co-electrospun gelatin/insulin fiber formulation for transbuccal insulin delivery

Author keywords

electrospun gelatin fiber; insulin; semi interpenetrating network; transbuccal delivery

Indexed keywords

ANTIDIABETIC AGENT; CROSS LINKING REAGENT; DRUG CARRIER; GELATIN; INSULIN; MACROGOL DERIVATIVE; POLY(ETHYLENE GLYCOL)DIACRYLATE;

EID: 84934759151     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1461-9     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 84873275131 scopus 로고    scopus 로고
    • Methods for insulin delivery and glucose monitoring in diabetes: Summary of a comparative effectiveness review
    • 22984955
    • Golden SH, Sapir T. Methods for insulin delivery and glucose monitoring in diabetes: summary of a comparative effectiveness review. J Manag Care Pharm. 2012;18(6 Suppl):S1-17.
    • (2012) J Manag Care Pharm , vol.18 , Issue.SUPPL. 6 , pp. 1-17
    • Golden, S.H.1    Sapir, T.2
  • 2
    • 26644444777 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in buccal drug delivery
    • 1:CAS:528:DC%2BD2MXhtFSisL7O 16183164
    • Salamat-Miller N, Chittchang M, Johnston TP. The use of mucoadhesive polymers in buccal drug delivery. Adv Drug Deliv Rev. 2005;57(11):1666-91.
    • (2005) Adv Drug Deliv Rev , vol.57 , Issue.11 , pp. 1666-1691
    • Salamat-Miller, N.1    Chittchang, M.2    Johnston, T.P.3
  • 3
    • 80054061227 scopus 로고    scopus 로고
    • A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery
    • 1:CAS:528:DC%2BC3MXhtlWlsbrF 21925726
    • Chen MC, Sonaje K, Chen KJ, Sung HW. A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery. Biomaterials. 2011;32(36):9826-38.
    • (2011) Biomaterials , vol.32 , Issue.36 , pp. 9826-9838
    • Chen, M.C.1    Sonaje, K.2    Chen, K.J.3    Sung, H.W.4
  • 4
    • 84869786430 scopus 로고    scopus 로고
    • Novel non-invasive methods of insulin delivery
    • 1:CAS:528:DC%2BC38XhslWktbrJ 23098366
    • Soares S, Costa A, Sarmento B. Novel non-invasive methods of insulin delivery. Expert Opin Drug Deliv. 2012;9(12):1539-58.
    • (2012) Expert Opin Drug Deliv , vol.9 , Issue.12 , pp. 1539-1558
    • Soares, S.1    Costa, A.2    Sarmento, B.3
  • 5
    • 36248965689 scopus 로고    scopus 로고
    • Current challenges in non-invasive insulin delivery systems: A comparative review
    • 1:CAS:528:DC%2BD2sXhtlCrtr%2FI
    • el Khafagy S, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Deliv Rev. 2007;59(15):1521-46.
    • (2007) Adv Drug Deliv Rev , vol.59 , Issue.15 , pp. 1521-1546
    • El Khafagy, S.1    Morishita, M.2    Onuki, Y.3    Takayama, K.4
  • 6
    • 84863510349 scopus 로고    scopus 로고
    • An overview of natural polymers for oral insulin delivery
    • 1:CAS:528:DC%2BC38XmsVGrtbo%3D 22521664
    • Sonia TA, Sharma CP. An overview of natural polymers for oral insulin delivery. Drug Discov Today. 2012;17(13-14):784-92.
    • (2012) Drug Discov Today , vol.17 , Issue.13-14 , pp. 784-792
    • Sonia, T.A.1    Sharma, C.P.2
  • 7
    • 33747884001 scopus 로고    scopus 로고
    • Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation
    • 1:CAS:528:DC%2BD28XovF2ksbk%3D 16859800
    • Cui F, Shi K, Zhang L, Tao A, Kawashima Y. Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: preparation, in vitro characterization and in vivo evaluation. J Control Release. 2006;114(2):242-50.
    • (2006) J Control Release , vol.114 , Issue.2 , pp. 242-250
    • Cui, F.1    Shi, K.2    Zhang, L.3    Tao, A.4    Kawashima, Y.5
  • 8
    • 33847666114 scopus 로고    scopus 로고
    • Preparation of insulin loaded PLGA-Hp55 nanoparticles for oral delivery
    • 1:CAS:528:DC%2BD2sXhsFGmtbg%3D 17051590
    • Cui FD, Tao AJ, Cun DM, Zhang LQ, Shi K. Preparation of insulin loaded PLGA-Hp55 nanoparticles for oral delivery. J Pharm Sci. 2007;96(2):421-7.
    • (2007) J Pharm Sci , vol.96 , Issue.2 , pp. 421-427
    • Cui, F.D.1    Tao, A.J.2    Cun, D.M.3    Zhang, L.Q.4    Shi, K.5
  • 9
    • 84872308929 scopus 로고    scopus 로고
    • Nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: Preparation, characterization, and hypoglycemic effect in rats
    • 3534302 23293517
    • Li X, Qi J, Xie Y, Zhang X, Hu S, Xu Y, et al. Nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: preparation, characterization, and hypoglycemic effect in rats. Int J Nanomedicine. 2013;8:23-32.
    • (2013) Int J Nanomedicine , vol.8 , pp. 23-32
    • Li, X.1    Qi, J.2    Xie, Y.3    Zhang, X.4    Hu, S.5    Xu, Y.6
  • 10
    • 84866686290 scopus 로고    scopus 로고
    • Chitosan-zinc-insulin complex incorporated thermosensitive polymer for controlled delivery of basal insulin in vivo
    • 1:CAS:528:DC%2BC38XhsFansLzL 22902516
    • Oak M, Singh J. Chitosan-zinc-insulin complex incorporated thermosensitive polymer for controlled delivery of basal insulin in vivo. J Control Release. 2012;163(2):145-53.
    • (2012) J Control Release , vol.163 , Issue.2 , pp. 145-153
    • Oak, M.1    Singh, J.2
  • 11
    • 33846940490 scopus 로고    scopus 로고
    • A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin
    • 1:CAS:528:DC%2BD2sXhsFCgtbc%3D 17239471
    • Chalasani KB, Russell-Jones GJ, Yandrapu SK, Diwan PV, Jain SK. A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin. J Control Release. 2007;117(3):421-9.
    • (2007) J Control Release , vol.117 , Issue.3 , pp. 421-429
    • Chalasani, K.B.1    Russell-Jones, G.J.2    Yandrapu, S.K.3    Diwan, P.V.4    Jain, S.K.5
  • 12
    • 1542509567 scopus 로고    scopus 로고
    • Oral insulin delivery: The potential of thiolated chitosan-insulin tablets on non-diabetic rats
    • 1:CAS:528:DC%2BD2cXitVKgtrk%3D 15023465
    • Krauland AH, Guggi D, Bernkop-Schnürch A. Oral insulin delivery: the potential of thiolated chitosan-insulin tablets on non-diabetic rats. J Control Release. 2004;95(3):547-55.
    • (2004) J Control Release , vol.95 , Issue.3 , pp. 547-555
    • Krauland, A.H.1    Guggi, D.2    Bernkop-Schnürch, A.3
  • 13
    • 60849130683 scopus 로고    scopus 로고
    • In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
    • 1:CAS:528:DC%2BD1MXisVClsLo%3D 19176244
    • Sonaje K, Lin Y-H, Juang J-H, Wey S-P, Chen C-T, Sung H-W. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials. 2009;30(12):2329-39.
    • (2009) Biomaterials , vol.30 , Issue.12 , pp. 2329-2339
    • Sonaje, K.1    Lin, Y.-H.2    Juang, J.-H.3    Wey, S.-P.4    Chen, C.-T.5    Sung, H.-W.6
  • 14
    • 34447577190 scopus 로고    scopus 로고
    • Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
    • 1:CAS:528:DC%2BD2sXhtVSktbjL 17707540
    • Chalasani KB, Russell-Jones GJ, Jain AK, Diwan PV, Jain SK. Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles. J Control Release. 2007;122(2):141-50.
    • (2007) J Control Release , vol.122 , Issue.2 , pp. 141-150
    • Chalasani, K.B.1    Russell-Jones, G.J.2    Jain, A.K.3    Diwan, P.V.4    Jain, S.K.5
  • 15
    • 84867067096 scopus 로고    scopus 로고
    • Electrospun nanofibers for regenerative medicine
    • 1:CAS:528:DC%2BC38Xit1yku7Y%3D 23184683
    • Liu W, Thomopoulos S, Xia Y. Electrospun nanofibers for regenerative medicine. Adv Healthc Mater. 2012;1(1):10-25.
    • (2012) Adv Healthc Mater , vol.1 , Issue.1 , pp. 10-25
    • Liu, W.1    Thomopoulos, S.2    Xia, Y.3
  • 16
    • 33746468534 scopus 로고    scopus 로고
    • Buccal bioadhesive drug delivery-a promising option for orally less efficient drugs
    • 1:CAS:528:DC%2BD28XnsFCrtrw%3D 16828915
    • Sudhakar Y, Kuotsu K, Bandyopadhyay AK. Buccal bioadhesive drug delivery-a promising option for orally less efficient drugs. J Control Release. 2006;114(1):15-40.
    • (2006) J Control Release , vol.114 , Issue.1 , pp. 15-40
    • Sudhakar, Y.1    Kuotsu, K.2    Bandyopadhyay, A.K.3
  • 17
    • 0035895143 scopus 로고    scopus 로고
    • Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin
    • 1:CAS:528:DC%2BD3MXmvFKrsA%3D%3D 11165086
    • Morishita M, Barichello JM, Takayama K, Chiba Y, Tokiwa S, Nagai T. Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin. Int J Pharm. 2001;212(2):289-93.
    • (2001) Int J Pharm , vol.212 , Issue.2 , pp. 289-293
    • Morishita, M.1    Barichello, J.M.2    Takayama, K.3    Chiba, Y.4    Tokiwa, S.5    Nagai, T.6
  • 18
    • 84859436289 scopus 로고    scopus 로고
    • Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): A potential approach for buccal delivery of macromolecules
    • 1:CAS:528:DC%2BC38XktFShu7Y%3D 22405987
    • Giovino C, Ayensu I, Tetteh J, Boateng JS. Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): a potential approach for buccal delivery of macromolecules. Int J Pharm. 2012;428(1-2):143-51.
    • (2012) Int J Pharm , vol.428 , Issue.1-2 , pp. 143-151
    • Giovino, C.1    Ayensu, I.2    Tetteh, J.3    Boateng, J.S.4
  • 19
    • 84881528437 scopus 로고    scopus 로고
    • An integrated buccal delivery system combining chitosan films impregnated with peptide loaded PEG-b-PLA nanoparticles
    • 1:CAS:528:DC%2BC3sXhslWhsL%2FJ 23928054
    • Giovino C, Ayensu I, Tetteh J, Boateng JS. An integrated buccal delivery system combining chitosan films impregnated with peptide loaded PEG-b-PLA nanoparticles. Colloids Surf B: Biointerfaces. 2013;112:9-15.
    • (2013) Colloids Surf B: Biointerfaces , vol.112 , pp. 9-15
    • Giovino, C.1    Ayensu, I.2    Tetteh, J.3    Boateng, J.S.4
  • 20
    • 66249125953 scopus 로고    scopus 로고
    • Preparation and evaluation of chitosan-ethylenediaminetetraacetic acid hydrogel films for the mucoadhesive transbuccal delivery of insulin
    • Cui F, He C, He M, Tang C, Yin L, Qian F, et al. Preparation and evaluation of chitosan-ethylenediaminetetraacetic acid hydrogel films for the mucoadhesive transbuccal delivery of insulin. J Biomed Mater Res. 2009;89(4):1063-71.
    • (2009) J Biomed Mater Res , vol.89 , Issue.4 , pp. 1063-1071
    • Cui, F.1    He, C.2    He, M.3    Tang, C.4    Yin, L.5    Qian, F.6
  • 21
    • 84877575080 scopus 로고    scopus 로고
    • Protein-coated nanoparticles embedded in films as delivery platforms
    • 1:CAS:528:DC%2BC3sXos1KnsLw%3D 23647676
    • Morales JO, Ross AC, McConville JT. Protein-coated nanoparticles embedded in films as delivery platforms. J Pharm Pharmacol. 2013;65(6):827-38.
    • (2013) J Pharm Pharmacol , vol.65 , Issue.6 , pp. 827-838
    • Morales, J.O.1    Ross, A.C.2    McConville, J.T.3
  • 22
    • 84861600027 scopus 로고    scopus 로고
    • In vitro characterisation of chitosan based xerogels for potential buccal delivery of proteins
    • 1:CAS:528:DC%2BC38XmslOjtb4%3D 24750883
    • Ayensu I, Mitchell JC, Boateng JS. In vitro characterisation of chitosan based xerogels for potential buccal delivery of proteins. Carbohydr Polym. 2012;89(3):935-41.
    • (2012) Carbohydr Polym , vol.89 , Issue.3 , pp. 935-941
    • Ayensu, I.1    Mitchell, J.C.2    Boateng, J.S.3
  • 23
    • 40049090999 scopus 로고    scopus 로고
    • Electrospinning: Applications in drug delivery and tissue engineering
    • 1:CAS:528:DC%2BD1cXivFKntrw%3D 18281090
    • Sill TJ, von Recum HA. Electrospinning: applications in drug delivery and tissue engineering. Biomaterials. 2008;29(13):1989-2006.
    • (2008) Biomaterials , vol.29 , Issue.13 , pp. 1989-2006
    • Sill, T.J.1    Von Recum, H.A.2
  • 24
    • 84879889647 scopus 로고    scopus 로고
    • Semi-interpenetrating network (sIPN) gelatin nanofiber scaffolds for oral mucosal drug delivery
    • 1:CAS:528:DC%2BC3sXjsFChtbk%3D 3622783 23416578
    • Aduba Jr DC, Hammer JA, Yuan Q, Yeudall WA, Bowlin GL, Yang H. Semi-interpenetrating network (sIPN) gelatin nanofiber scaffolds for oral mucosal drug delivery. Acta Biomater. 2013;9(5):6576-84.
    • (2013) Acta Biomater , vol.9 , Issue.5 , pp. 6576-6584
    • Aduba, Jr.D.C.1    Hammer, J.A.2    Yuan, Q.3    Yeudall, W.A.4    Bowlin, G.L.5    Yang, H.6
  • 25
    • 77950171559 scopus 로고    scopus 로고
    • Synthesis and characterization of photocurable polyamidoamine dendrimer hydrogels as a versatile platform for tissue engineering and drug delivery
    • 1:CAS:528:DC%2BC3cXhtFKqurg%3D 2849659 20108892
    • Desai PN, Yuan Q, Yang H. Synthesis and characterization of photocurable polyamidoamine dendrimer hydrogels as a versatile platform for tissue engineering and drug delivery. Biomacromolecules. 2010;11(3):666-73.
    • (2010) Biomacromolecules , vol.11 , Issue.3 , pp. 666-673
    • Desai, P.N.1    Yuan, Q.2    Yang, H.3
  • 26
    • 84884372707 scopus 로고    scopus 로고
    • Biodegradable drug-eluting poly[lactic-co-glycol acid] nanofibers for the sustainable delivery of vancomycin to brain tissue: In vitro and in vivo studies
    • 1:CAS:528:DC%2BC3sXhtVeisL3E 3778423 23815098
    • Tseng Y-Y, Kao Y-C, Liao J-Y, Chen W-A, Liu S-J. Biodegradable drug-eluting poly[lactic-co-glycol acid] nanofibers for the sustainable delivery of vancomycin to brain tissue: in vitro and in vivo studies. ACS Chem Neurosci. 2013;4(9):1314-21.
    • (2013) ACS Chem Neurosci , vol.4 , Issue.9 , pp. 1314-1321
    • Tseng, Y.-Y.1    Kao, Y.-C.2    Liao, J.-Y.3    Chen, W.-A.4    Liu, S.-J.5
  • 27
    • 81155152705 scopus 로고    scopus 로고
    • The use of air-flow impedance to control fiber deposition patterns during electrospinning
    • 1:CAS:528:DC%2BC3MXhsVyksb7F 22054536
    • McClure MJ, Wolfe PS, Simpson DG, Sell SA, Bowlin GL. The use of air-flow impedance to control fiber deposition patterns during electrospinning. Biomaterials. 2012;33(3):771-9.
    • (2012) Biomaterials , vol.33 , Issue.3 , pp. 771-779
    • McClure, M.J.1    Wolfe, P.S.2    Simpson, D.G.3    Sell, S.A.4    Bowlin, G.L.5
  • 28
    • 84859463296 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARgamma signaling in human THP-1 macrophages
    • 1:CAS:528:DC%2BC38Xmsl2gtrY%3D 3330710 22275753
    • Xu L, Shen S, Ma Y, Kim JK, Rodriguez-Agudo D, Heuman DM, et al. 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARgamma signaling in human THP-1 macrophages. Am J Physiol Endocrinol Metab. 2012;302(7):E788-99.
    • (2012) Am J Physiol Endocrinol Metab , vol.302 , Issue.7 , pp. 788-799
    • Xu, L.1    Shen, S.2    Ma, Y.3    Kim, J.K.4    Rodriguez-Agudo, D.5    Heuman, D.M.6
  • 29
    • 36549010103 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation
    • 1:CAS:528:DC%2BD1cXnt1Kqsg%3D%3D 2185546 18054552
    • Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, Wolfe MM. Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology. 2007;133(6):1796-805.
    • (2007) Gastroenterology , vol.133 , Issue.6 , pp. 1796-1805
    • Song, D.H.1    Getty-Kaushik, L.2    Tseng, E.3    Simon, J.4    Corkey, B.E.5    Wolfe, M.M.6
  • 30
    • 57349087221 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway
    • 1:CAS:528:DC%2BD1cXhsFWgtb7K 2603552 18854425
    • Ma Y, Xu L, Rodriguez-Agudo D, Li X, Heuman DM, Hylemon PB, et al. 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway. Am J Physiol Endocrinol Metab. 2008;295(6):E1369-79.
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , Issue.6 , pp. 1369-1379
    • Ma, Y.1    Xu, L.2    Rodriguez-Agudo, D.3    Li, X.4    Heuman, D.M.5    Hylemon, P.B.6
  • 31
    • 81455136017 scopus 로고    scopus 로고
    • Transbuccal delivery of CNS therapeutic nanoparticles: Synthesis, characterization, and in vitro permeation studies
    • 1:CAS:528:DC%2BC3MXhtFOitL%2FE 3241219 22184511
    • Yuan Q, Fu Y, Kao WJ, Janigro D, Yang H. Transbuccal delivery of CNS therapeutic nanoparticles: synthesis, characterization, and in vitro permeation studies. ACS Chem Neurosci. 2011;2(11):676-83.
    • (2011) ACS Chem Neurosci , vol.2 , Issue.11 , pp. 676-683
    • Yuan, Q.1    Fu, Y.2    Kao, W.J.3    Janigro, D.4    Yang, H.5
  • 32
    • 68149181727 scopus 로고    scopus 로고
    • Drug release kinetics and transport mechanisms from semi-interpenetrating networks of gelatin and poly(ethylene glycol) diacrylate
    • 1:CAS:528:DC%2BD1MXns1Cqsr4%3D 19554430
    • Fu Y, Kao WJ. Drug release kinetics and transport mechanisms from semi-interpenetrating networks of gelatin and poly(ethylene glycol) diacrylate. Pharm Res. 2009;26(9):2115-24.
    • (2009) Pharm Res , vol.26 , Issue.9 , pp. 2115-2124
    • Fu, Y.1    Kao, W.J.2
  • 33
    • 78650993581 scopus 로고    scopus 로고
    • Tuning the non-equilibrium state of a drug-encapsulated poly(ethylene glycol) hydrogel for stem and progenitor cell mobilization
    • 1:CAS:528:DC%2BC3MXmtVOrtg%3D%3D 3021707 21144582
    • Liang Y, Jensen TW, Roy EJ, Cha C, Devolder RJ, Kohman RE, et al. Tuning the non-equilibrium state of a drug-encapsulated poly(ethylene glycol) hydrogel for stem and progenitor cell mobilization. Biomaterials. 2011;32(7):2004-12.
    • (2011) Biomaterials , vol.32 , Issue.7 , pp. 2004-2012
    • Liang, Y.1    Jensen, T.W.2    Roy, E.J.3    Cha, C.4    Devolder, R.J.5    Kohman, R.E.6
  • 34
    • 77950275414 scopus 로고    scopus 로고
    • Mechanical and cell viability properties of crosslinked low- and high-molecular weight poly(ethylene glycol) diacrylate blends
    • Mazzoccoli JP, Feke DL, Baskaran H, Pintauro PN. Mechanical and cell viability properties of crosslinked low- and high-molecular weight poly(ethylene glycol) diacrylate blends. J Biomed Mater Res. 2010;93(2):558-66.
    • (2010) J Biomed Mater Res , vol.93 , Issue.2 , pp. 558-566
    • Mazzoccoli, J.P.1    Feke, D.L.2    Baskaran, H.3    Pintauro, P.N.4
  • 35
    • 5444223013 scopus 로고    scopus 로고
    • Photopolymerization of poly(ethylene glycol) diacrylate on eosin-functionalized surfaces
    • 1:CAS:528:DC%2BD2cXmvFylsLk%3D 15379488
    • Kizilel S, Perez-Luna VH, Teymour F. Photopolymerization of poly(ethylene glycol) diacrylate on eosin-functionalized surfaces. Langmuir. 2004;20(20):8652-8.
    • (2004) Langmuir , vol.20 , Issue.20 , pp. 8652-8658
    • Kizilel, S.1    Perez-Luna, V.H.2    Teymour, F.3
  • 36
    • 79961187336 scopus 로고    scopus 로고
    • Visible light photoinitiation of mesenchymal stem cell-laden bioresponsive hydrogels
    • 1:CAS:528:DC%2BC3MXhtFSktL%2FP 21761391 discussion 55
    • Bahney CS, Lujan TJ, Hsu CW, Bottlang M, West JL, Johnstone B. Visible light photoinitiation of mesenchymal stem cell-laden bioresponsive hydrogels. Eur Cell Mater. 2011;22:43-55. discussion 55.
    • (2011) Eur Cell Mater , vol.22 , pp. 43-55
    • Bahney, C.S.1    Lujan, T.J.2    Hsu, C.W.3    Bottlang, M.4    West, J.L.5    Johnstone, B.6
  • 37
    • 0037934650 scopus 로고    scopus 로고
    • Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing
    • 1:CAS:528:DC%2BD3sXlt1Wrurg%3D 164627 12808134
    • Jiang ZY, Zhou QL, Coleman KA, Chouinard M, Boese Q, Czech MP. Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing. Proc Natl Acad Sci U S A. 2003;100(13):7569-74.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.13 , pp. 7569-7574
    • Jiang, Z.Y.1    Zhou, Q.L.2    Coleman, K.A.3    Chouinard, M.4    Boese, Q.5    Czech, M.P.6
  • 39
    • 0038354770 scopus 로고    scopus 로고
    • Cell interaction with protein-loaded interpenetrating networks containing modified gelatin and poly(ethylene glycol) diacrylate
    • 1:CAS:528:DC%2BD3sXkvFels7s%3D 12834587
    • Burmania JA, Stevens KR, Kao WJ. Cell interaction with protein-loaded interpenetrating networks containing modified gelatin and poly(ethylene glycol) diacrylate. Biomaterials. 2003;24(22):3921-30.
    • (2003) Biomaterials , vol.24 , Issue.22 , pp. 3921-3930
    • Burmania, J.A.1    Stevens, K.R.2    Kao, W.J.3
  • 40
    • 1942517440 scopus 로고    scopus 로고
    • Tissue adhesiveness and host response of in situ photopolymerizable interpenetrating networks containing methylprednisolone acetate
    • Zilinski JL, Kao WJ. Tissue adhesiveness and host response of in situ photopolymerizable interpenetrating networks containing methylprednisolone acetate. J Biomed Mater Res. 2004;68(2):392-400.
    • (2004) J Biomed Mater Res , vol.68 , Issue.2 , pp. 392-400
    • Zilinski, J.L.1    Kao, W.J.2
  • 41
    • 84863693562 scopus 로고    scopus 로고
    • Effect of soybean-lecithin as an enhancer of buccal mucosa absorption of insulin
    • 22766717
    • Tian W, Hu Q, Xu Y, Xu Y. Effect of soybean-lecithin as an enhancer of buccal mucosa absorption of insulin. Biomed Mater Eng. 2012;22(1-3):171-8.
    • (2012) Biomed Mater Eng , vol.22 , Issue.1-3 , pp. 171-178
    • Tian, W.1    Hu, Q.2    Xu, Y.3    Xu, Y.4
  • 42
    • 0036435734 scopus 로고    scopus 로고
    • Hypoglycaemic effect of a novel insulin buccal formulation on rabbits
    • 1:CAS:528:DC%2BD38Xot12lt7g%3D 12419651
    • Xu HB, Huang KX, Zhu YS, Gao QH, Wu QZ, Tian WQ, et al. Hypoglycaemic effect of a novel insulin buccal formulation on rabbits. Pharmacol Res. 2002;46(5):459-67.
    • (2002) Pharmacol Res , vol.46 , Issue.5 , pp. 459-467
    • Xu, H.B.1    Huang, K.X.2    Zhu, Y.S.3    Gao, Q.H.4    Wu, Q.Z.5    Tian, W.Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.