Tuning the non-equilibrium state of a drug-encapsulated poly(ethylene glycol) hydrogel for stem and progenitor cell mobilization

Biomaterials

Volumn 32, Issue 7, 2011, Pages 2004-2012

  Liang, Youyun ^a,b   Jensen, Tor W ^a   Roy, Edward J ^a   Cha, Chaenyung ^a   DeVolder, Ross J ^a   Kohman, Richie E ^a   Zhang, Bao Zhong ^a   Textor, Kyle B ^a   Rund, Lauretta A ^a   Schook, Lawrence B ^a   Tong, Yen Wah ^b   Kong, Hyunjoon ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Degradation rate; Granulocyte colony stimulating factor (GCSF); Michael Addition; Poly(ethyleneimine); Rigidity

Indexed keywords

BIODEGRADABLE HYDROGELS; BRANCHED ARCHITECTURE; BULK PLASTICS; CONTROLLABLE DEGRADATION; DEGRADATION RATE; DRUG MOLECULES; DRUG-RELEASE RATE; ENDOTHELIAL PROGENITOR CELLS; GRANULOCYTE-COLONY STIMULATING FACTOR; INITIAL ELASTIC MODULUS; INTRAMUSCULAR ADMINISTRATION; KEY FACTORS; MICHAEL-ADDITION; MOLECULAR THERAPY; MONONUCLEAR CELLS; NON EQUILIBRIUM; NONEQUILIBRIUM STATE; POLY(ETHYLENE GLYCOL) HYDROGEL; POLY(ETHYLENEIMINE); POLYETHYLENE GLYCOL DIACRYLATE; PROGENITOR CELL; THERAPEUTIC EFFICACY;

CONTROLLABILITY; CONTROLLED DRUG DELIVERY; DEGRADATION; DRUG PRODUCTS; DRUG THERAPY; ELASTIC MODULI; ENDOTHELIAL CELLS; ETHYLENE; ETHYLENE GLYCOL; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RIGIDITY; STEM CELLS; STIFFNESS;

HYDROGELS;

GRANULOCYTE COLONY STIMULATING FACTOR; MACROGOL; PLASTIC; POLYETHYLENEIMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DEGRADATION; DRUG RELEASE; ENCAPSULATION; EXPERIMENTAL PIG; FEMALE; HYDROGEL; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RIGIDITY; STEM CELL MOBILIZATION; YOUNG MODULUS;

ANIMALS; CHICK EMBRYO; CHICKENS; DRUG DELIVERY SYSTEMS; FEMALE; HYDROGEL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; POLYETHYLENE GLYCOLS; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; STEM CELLS;

EID: 78650993581     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.11.021     Document Type: Article

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