Hypoglycaemic effect of a novel insulin buccal formulation on rabbits

Pharmacological Research

Volumn 46, Issue 5, 2002, Pages 459-467

  Xu, Hui Bi ^a   Huang, Kai Xun ^a   Zhu, Yu Shan ^a   Gao, Qiu Hua ^a   Wu, Qing Zhi ^a   Tian, Wei Qun ^a   Sheng, Xi Qun ^a   Chen, Ze Xian ^a   Gao, Zhong Hong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Absorption enhancer; Insulin; Soybean lecithin; Transmucosal delivery

Indexed keywords

ALLOXAN; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; GLUCOSE; INSULIN; PHOSPHATIDYLCHOLINE; STREPTOZOCIN; ANTIDIABETIC AGENT; EXCIPIENT; PROPANEDIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CALCULATION; CHEEK MUCOSA; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG PENETRATION; FEMALE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; TREATMENT OUTCOME; ADSORPTION; ANIMAL; BIOAVAILABILITY; BUCCAL DRUG ADMINISTRATION; CHEMISTRY; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; MOUTH MUCOSA; RAT; SPRAGUE DAWLEY RAT;

ADMINISTRATION, BUCCAL; ADSORPTION; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EXCIPIENTS; FEMALE; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MOUTH MUCOSA; PHOSPHATIDYLCHOLINES; PROPYLENE GLYCOLS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036435734     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043661802002049     Document Type: Article

References (24)

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