1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP

European Journal of Pharmacology

Volumn 567, Issue 3, 2007, Pages 193-197

  Park, Byung Chul ^a   Thapa, Dinesh ^a   Lee, Yoon Seok ^a   Kwak, Mi Kyoung ^a   Lee, Eung Seok ^a   Choi, Han Gon ^a   Yong, Chul Soon ^a   Kim, Jung Ae ^a  

^a Yeungnam University   (South Korea)

Author keywords

1 furan 2 yl 3 pyridin 2 yl propenone; MMP 2; MMP 9; MT1 MMP; TIMP

Indexed keywords

1 FURAN 2 YL 3 PYRIDIN 2 YL PROPENONE; ANTINEOPLASTIC AGENT; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID TUMOR;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME PRECURSORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FURANS; GELATINASES; HUMANS; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; PROPANE; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TISSUE INHIBITOR OF METALLOPROTEINASE-1; WOUNDS AND INJURIES;

EID: 34250852876     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.04.014     Document Type: Article

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