Serotonin regulates innate immune responses of colon epithelial cells through Nox2-derived reactive oxygen species

Free Radical Biology and Medicine

Volumn 69, Issue , 2014, Pages 377-389

  Regmi, Sushil Chandra ^a   Park, Su Young ^a   Ku, Sae Kwang ^b   Kim, Jung Ae ^a  

^a Yeungnam University   (South Korea)

^b Daegu Hany University   (South Korea)

Author keywords

5 HT; Free radicals; Inflammatory bowel disease; Innate immune response; Nox2; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; ACID; ANTIOXIDANT; APOCYNIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PROTEIN P67; PYRROLIDINE DITHIOCARBAMATE; RAC PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RS 39604; SEROTONIN; SEROTONIN ANTAGONIST; SMALL INTERFERING RNA; TRINITROBENZENESULFONIC ACID; TROPISETRON; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL STRAIN CACO 2; COLITIS; COLON INJURY; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME INDUCTION; EPITHELIUM CELL; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; KNOCKOUT MOUSE; LOW DRUG DOSE; MONOCYTE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WILD TYPE;

5-HT; FREE RADICALS; INFLAMMATORY BOWEL DISEASE; INNATE IMMUNE RESPONSE; NOX2; REACTIVE OXYGEN SPECIES;

ANIMALS; CACO-2 CELLS; CELL ADHESION; COLITIS; COLON; EPITHELIAL CELLS; HT29 CELLS; HUMANS; IMMUNITY, INNATE; INFLAMMATORY BOWEL DISEASES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; REACTIVE OXYGEN SPECIES; SEROTONIN; SIGNAL TRANSDUCTION;

EID: 84895522834     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.02.003     Document Type: Article

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