메뉴 건너뛰기




Volumn 16, Issue 4, 2015, Pages 485-501

A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults

Author keywords

Aging; Drosophila; Oxidative stress; SOD1; SOD2

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MYOCYTE ENHANCER FACTOR 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; DROSOPHILA PROTEIN; PROTEIN AGGREGATE;

EID: 84933676370     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-015-9570-3     Document Type: Article
Times cited : (52)

References (49)
  • 1
    • 71549124077 scopus 로고    scopus 로고
    • Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates
    • COI: 1:CAS:528:DC%2BD1MXhsV2msbbO, PID: 19815008
    • Agrawal L, Louboutin JP, Marusich E, Reyes BA, Van Bockstaele EJ, Strayer DS (2010) Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res 1306:116–130. doi:10.1016/j.brainres.2009.09.113
    • (2010) Brain Res , vol.1306 , pp. 116-130
    • Agrawal, L.1    Louboutin, J.P.2    Marusich, E.3    Reyes, B.A.4    Van Bockstaele, E.J.5    Strayer, D.S.6
  • 2
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • COI: 1:CAS:528:DC%2BD2MXitVWnurg%3D, PID: 15734681
    • Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120:483–495. doi:10.1016/j.cell.2005.02.001
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • COI: 1:CAS:528:DyaK3MXktVGqur8%3D, PID: 2010041
    • Baynes JW (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40:405–412. doi:10.2337/diab.40.4.405
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 72949108454 scopus 로고    scopus 로고
    • Modelling Parkinson’s disease in Drosophila
    • COI: 1:CAS:528:DC%2BD1MXhsFClurrK
    • Botella JA, Bayersdorfer F, Gmeiner F, Schneuwly S (2009) Modelling Parkinson’s disease in Drosophila. NeuroMol Med 11:268–280. doi:10.1007/s12017-009-8098-6
    • (2009) NeuroMol Med , vol.11 , pp. 268-280
    • Botella, J.A.1    Bayersdorfer, F.2    Gmeiner, F.3    Schneuwly, S.4
  • 5
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: mechanisms, mutation, and disease
    • COI: 1:CAS:528:DC%2BD3sXltFeru78%3D, PID: 12832285
    • Cooke MS, Evans MD, Dizdaroglu M, Lunec J (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 17:1195–1214
    • (2003) FASEB J , vol.17 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 6
    • 84855394783 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction, and aging
    • Cui H, Kong Y, Zhang H (2011) Oxidative stress, mitochondrial dysfunction, and aging. J Signal Transduct 2012:13. doi:10.1155/2012/646354
    • (2011) J Signal Transduct , vol.2012 , pp. 13
    • Cui, H.1    Kong, Y.2    Zhang, H.3
  • 7
    • 0035890871 scopus 로고    scopus 로고
    • Selectivity of protein oxidative damage during aging in Drosophila melanogaster
    • COI: 1:CAS:528:DC%2BD3MXovVCltbs%3D, PID: 11696009
    • Das N, Levine RL, Orr WC, Sohal RS (2001) Selectivity of protein oxidative damage during aging in Drosophila melanogaster. Biochem J 360:209–216
    • (2001) Biochem J , vol.360 , pp. 209-216
    • Das, N.1    Levine, R.L.2    Orr, W.C.3    Sohal, R.S.4
  • 8
    • 78650918920 scopus 로고    scopus 로고
    • FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
    • COI: 1:CAS:528:DC%2BC3cXhsVygsLfJ, PID: 21111239
    • Demontis F, Perrimon N (2010) FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 143:813–825. doi:10.1016/j.cell.2010.10.007
    • (2010) Cell , vol.143 , pp. 813-825
    • Demontis, F.1    Perrimon, N.2
  • 9
    • 0036741796 scopus 로고    scopus 로고
    • GAL4 system in Drosophila: a fly geneticist’s swiss army knife
    • COI: 1:CAS:528:DC%2BD38XosFKnsrk%3D, PID: 12324939
    • Duffy JB (2002) GAL4 system in Drosophila: a fly geneticist’s swiss army knife. Genesis 34:1–15. doi:10.1002/gene.10150
    • (2002) Genesis , vol.34
    • Duffy, J.B.1
  • 10
    • 0346100684 scopus 로고    scopus 로고
    • A Sod2 null mutation confers severely reduced adult life span in Drosophila
    • COI: 1:CAS:528:DC%2BD2cXnvFOktg%3D%3D, PID: 14704205
    • Duttaroy A, Paul A, Kundu M, Belton A (2003) A Sod2 null mutation confers severely reduced adult life span in Drosophila. Genetics 165:2295–2299
    • (2003) Genetics , vol.165 , pp. 2295-2299
    • Duttaroy, A.1    Paul, A.2    Kundu, M.3    Belton, A.4
  • 11
    • 25144463436 scopus 로고    scopus 로고
    • Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster
    • COI: 1:CAS:528:DC%2BD2MXoslKgtLk%3D, PID: 15853766
    • Ferguson M, Mockett RJ, Shen Y, Orr WC, Sohal RS (2005) Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster. Biochem J 390:501–511. doi:10.1042/bj20042130
    • (2005) Biochem J , vol.390 , pp. 501-511
    • Ferguson, M.1    Mockett, R.J.2    Shen, Y.3    Orr, W.C.4    Sohal, R.S.5
  • 12
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • COI: 1:CAS:528:DC%2BD3cXotFGltb0%3D, PID: 11089981
    • Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408:239–247. doi:10.1038/35041687
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 13
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
    • COI: 1:CAS:528:DyaK1MXislGrs7w%3D, PID: 10212301
    • Fujimura M, Morita-Fujimura Y, Kawase M, Copin JC, Calagui B, Epstein CJ, Chan PH (1999) Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci 19:3414–3422
    • (1999) J Neurosci , vol.19 , pp. 3414-3422
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3    Copin, J.C.4    Calagui, B.5    Epstein, C.J.6    Chan, P.H.7
  • 14
    • 66749126389 scopus 로고    scopus 로고
    • Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?
    • COI: 1:CAS:528:DC%2BD1MXptFehtLY%3D, PID: 19411855
    • Gems D, Doonan R (2009) Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong? Cell Cycle 8:1681–1687. doi:10.4161/cc.8.11.8595
    • (2009) Cell Cycle , vol.8 , pp. 1681-1687
    • Gems, D.1    Doonan, R.2
  • 15
    • 70350170145 scopus 로고    scopus 로고
    • Mitochondrial superoxide radicals differentially affect muscle activity and neural function
    • COI: 1:CAS:528:DC%2BD1MXhtlWksbbL, PID: 19546321
    • Godenschwege T, Forde R, Davis CP, Paul A, Beckwith K, Duttaroy A (2009) Mitochondrial superoxide radicals differentially affect muscle activity and neural function. Genetics 183:175–184. doi:10.1534/genetics.109.103515
    • (2009) Genetics , vol.183 , pp. 175-184
    • Godenschwege, T.1    Forde, R.2    Davis, C.P.3    Paul, A.4    Beckwith, K.5    Duttaroy, A.6
  • 16
    • 0029824431 scopus 로고    scopus 로고
    • Antioxidants in human health and disease
    • COI: 1:CAS:528:DyaK28XksFKrtbY%3D, PID: 8839918
    • Halliwell B (1996) Antioxidants in human health and disease. Annu Rev Nutr 16:33–50. doi:10.1146/annurev.nu.16.070196.000341
    • (1996) Annu Rev Nutr , vol.16 , pp. 33-50
    • Halliwell, B.1
  • 18
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • COI: 1:STN:280:DyaG28%2FosVygsw%3D%3D, PID: 13332224
    • Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298–300
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 19
    • 0015319592 scopus 로고
    • The biologic clock: the mitochondria?
    • Harman D (1972) The biologic clock: the mitochondria? J Am Geriatr Soc 4:145–147
    • (1972) J Am Geriatr Soc , vol.4 , pp. 145-147
    • Harman, D.1
  • 20
    • 70350439125 scopus 로고    scopus 로고
    • Overexpression of Mn superoxide dismutase does not increase life span in mice
    • Jang YC, Pérez VI, Song W et al (2009) Overexpression of Mn superoxide dismutase does not increase life span in mice. J Gerontol Ser A 11:1114–1125. doi:10.1093/gerona/glp100
    • (2009) J Gerontol Ser A , vol.11 , pp. 1114-1125
    • Jang, Y.C.1    Pérez, V.I.2    Song, W.3
  • 21
    • 79958180629 scopus 로고    scopus 로고
    • Identification of Drosophila SOD3 and its protective role against phototoxic damage to cells
    • COI: 1:CAS:528:DC%2BC3MXnsVShsbY%3D, PID: 21635891
    • Jung I, Kim TY, Kim-Ha J (2011) Identification of Drosophila SOD3 and its protective role against phototoxic damage to cells. FEBS Lett 585:1973–1978. doi:10.1016/j.febslet.2011.05.033
    • (2011) FEBS Lett , vol.585 , pp. 1973-1978
    • Jung, I.1    Kim, T.Y.2    Kim-Ha, J.3
  • 22
    • 0036192957 scopus 로고    scopus 로고
    • Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals stroke
    • COI: 1:CAS:528:DC%2BD38XisVKktrs%3D
    • Kim GW, Kondo T, Noshita N, Chan PH (2002) Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals stroke. J Cereb Circ 33:809–815
    • (2002) J Cereb Circ , vol.33 , pp. 809-815
    • Kim, G.W.1    Kondo, T.2    Noshita, N.3    Chan, P.H.4
  • 23
    • 0037136563 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    • COI: 1:CAS:528:DC%2BD38XntFSgs7k%3D, PID: 12239572
    • Kops GJ, Dansen TB, Poldermanet PE et al (2002) Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419:316–321. doi:10.1038/nature01036
    • (2002) Nature , vol.419 , pp. 316-321
    • Kops, G.J.1    Dansen, T.B.2    Poldermanet, P.E.3
  • 24
    • 12344276944 scopus 로고    scopus 로고
    • Superoxide dismutase evolution and life span regulation
    • COI: 1:CAS:528:DC%2BD2MXms1Oqug%3D%3D, PID: 15664623
    • Landis GN, Tower J (2005) Superoxide dismutase evolution and life span regulation. Mech Ageing Dev 126:365–379. doi:10.1016/j.mad.2004.08.012
    • (2005) Mech Ageing Dev , vol.126 , pp. 365-379
    • Landis, G.N.1    Tower, J.2
  • 25
    • 73749085674 scopus 로고    scopus 로고
    • When a theory of aging ages badly
    • COI: 1:CAS:528:DC%2BC3cXis1Wquw%3D%3D, PID: 19730800
    • Lapointe J, Hekimi S (2010) When a theory of aging ages badly. Cell Mol Life Sci 67:1–8. doi:10.1007/s00018-009-0138-8
    • (2010) Cell Mol Life Sci , vol.67
    • Lapointe, J.1    Hekimi, S.2
  • 26
    • 67649366540 scopus 로고    scopus 로고
    • Sod2 knockdown in the musculature has whole-organism consequences in Drosophila
    • COI: 1:CAS:528:DC%2BD1MXhtVSnt7nE, PID: 19545620
    • Martin I, Jones MA, Rhodenizer D, Zheng J, Warrick JM, Seroude L, Grotewiel M (2009) Sod2 knockdown in the musculature has whole-organism consequences in Drosophila. Free Radic Biol Med 47:803–813. doi:10.1016/j.freeradbiomed.2009.06.021
    • (2009) Free Radic Biol Med , vol.47 , pp. 803-813
    • Martin, I.1    Jones, M.A.2    Rhodenizer, D.3    Zheng, J.4    Warrick, J.M.5    Seroude, L.6    Grotewiel, M.7
  • 27
    • 34250810151 scopus 로고    scopus 로고
    • Age-related changes in climbing behavior and neural circuit physiology in Drosophila
    • COI: 1:STN:280:DC%2BD2s3jsVemtA%3D%3D, PID: 17443824
    • Martinez VG, Javadi CS, Ngo E, Ngo L, Lagow RD, Zhang B (2007) Age-related changes in climbing behavior and neural circuit physiology in Drosophila. Dev Neurobiol 67:778–791. doi:10.1002/dneu.20388
    • (2007) Dev Neurobiol , vol.67 , pp. 778-791
    • Martinez, V.G.1    Javadi, C.S.2    Ngo, E.3    Ngo, L.4    Lagow, R.D.5    Zhang, B.6
  • 28
    • 51649090972 scopus 로고    scopus 로고
    • Aging enhances indirect flight muscle fiber performance yet decreases flight ability in Drosophila
    • COI: 1:CAS:528:DC%2BD1cXhtVGqsrzJ, PID: 18515368
    • Miller MS, Bedrin NG, Callahan DM et al (2008) Aging enhances indirect flight muscle fiber performance yet decreases flight ability in Drosophila. Biophys J 95:2391–2401. doi:10.1529/biophysj.108.130005
    • (2008) Biophys J , vol.95 , pp. 2391-2401
    • Miller, M.S.1    Bedrin, N.G.2    Callahan, D.M.3
  • 29
    • 0037438869 scopus 로고    scopus 로고
    • Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity
    • COI: 1:CAS:528:DC%2BD3sXotVah, PID: 12521602
    • Mockett RJ, Bayne AC, Kwong LK, Orr WC, Sohal RS (2003) Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. Free Radic Biol Med 34:207–217
    • (2003) Free Radic Biol Med , vol.34 , pp. 207-217
    • Mockett, R.J.1    Bayne, A.C.2    Kwong, L.K.3    Orr, W.C.4    Sohal, R.S.5
  • 30
    • 78650169712 scopus 로고    scopus 로고
    • Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster
    • COI: 1:CAS:528:DC%2BC3cXhsFGgs73M, PID: 20923705
    • Mockett RJ, Sohal BH, Sohal RS (2010) Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster. Free Radic Biol Med 49:2028–2031. doi:10.1016/j.freeradbiomed.2010.09.029
    • (2010) Free Radic Biol Med , vol.49 , pp. 2028-2031
    • Mockett, R.J.1    Sohal, B.H.2    Sohal, R.S.3
  • 31
    • 0031974368 scopus 로고    scopus 로고
    • Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency
    • COI: 1:CAS:528:DyaK1cXjtVKquw%3D%3D, PID: 9412501
    • Murakami K, Kondo T, Kawase M, Li Y, Sato S, Chen SF, Chan PH (1998) Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci 18:205–213
    • (1998) J Neurosci , vol.18 , pp. 205-213
    • Murakami, K.1    Kondo, T.2    Kawase, M.3    Li, Y.4    Sato, S.5    Chen, S.F.6    Chan, P.H.7
  • 32
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • COI: 1:CAS:528:DyaK2cXhvVOlsr4%3D
    • Orr WC, Sohal RS (1994) Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science (New York, NY) 263:1128–1130
    • (1994) Science (New York, NY) , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 33
    • 0038712734 scopus 로고    scopus 로고
    • Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster
    • COI: 1:CAS:528:DC%2BD3sXltlKqsr4%3D, PID: 12743125
    • Orr WC, Mockett RJ, Benes JJ, Sohal RS (2003) Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J Biol Chem 278:26418–26422. doi:10.1074/jbc.M303095200
    • (2003) J Biol Chem , vol.278 , pp. 26418-26422
    • Orr, W.C.1    Mockett, R.J.2    Benes, J.J.3    Sohal, R.S.4
  • 34
    • 0031864164 scopus 로고    scopus 로고
    • Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
    • COI: 1:CAS:528:DyaK1cXls1Crurg%3D, PID: 9620775
    • Parkes TL, Elia AJ, Dickinson D, Hilliker AJ, Phillips JP, Boulianne GL (1998) Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat Genet 19:171–174. doi:10.1038/534
    • (1998) Nat Genet , vol.19 , pp. 171-174
    • Parkes, T.L.1    Elia, A.J.2    Dickinson, D.3    Hilliker, A.J.4    Phillips, J.P.5    Boulianne, G.L.6
  • 35
    • 37549056972 scopus 로고    scopus 로고
    • Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging
    • COI: 1:CAS:528:DC%2BD1cXhtlWitQ%3D%3D, PID: 18078670
    • Paul A, Belton A, Nag S, Martin I, Grotewiel MS, Duttaroy A (2007) Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging. Mech Ageing Dev 128:706–716. doi:10.1016/j.mad.2007.10.013
    • (2007) Mech Ageing Dev , vol.128 , pp. 706-716
    • Paul, A.1    Belton, A.2    Nag, S.3    Martin, I.4    Grotewiel, M.S.5    Duttaroy, A.6
  • 37
    • 0031666402 scopus 로고    scopus 로고
    • Ectopic gene expression in Drosophila using GAL4 system
    • COI: 1:CAS:528:DyaK1cXjtFant7w%3D, PID: 9608508
    • Phelps CB, Brand AH (1998) Ectopic gene expression in Drosophila using GAL4 system. Methods 14:367–379. doi:10.1006/meth.1998.0592
    • (1998) Methods , vol.14 , pp. 367-379
    • Phelps, C.B.1    Brand, A.H.2
  • 38
    • 0024547664 scopus 로고
    • Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity
    • Phillips JP, Campbell SD, Michaud D, Charbonneau M, Hilliker AJ (1989) Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc Natl Acad Sci USA 8:2761–2765
    • (1989) Proc Natl Acad Sci USA , vol.8 , pp. 2761-2765
    • Phillips, J.P.1    Campbell, S.D.2    Michaud, D.3    Charbonneau, M.4    Hilliker, A.J.5
  • 39
    • 84880514122 scopus 로고    scopus 로고
    • Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
    • COI: 1:CAS:528:DC%2BC3sXhtlCku7nM, PID: 23521918
    • Rahman MM, Sykiotis GP, Nishimura M, Bodmer R, Bohmann D (2013) Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell 12:554–562
    • (2013) Aging Cell , vol.12 , pp. 554-562
    • Rahman, M.M.1    Sykiotis, G.P.2    Nishimura, M.3    Bodmer, R.4    Bohmann, D.5
  • 40
    • 0025362247 scopus 로고
    • Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span
    • COI: 1:CAS:528:DyaK3cXksFKnur4%3D, PID: 2112250
    • Seto NO, Hayashi S, Tener GM (1990) Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span. Proc Natl Acad Sci USA 87:4270–4274
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4270-4274
    • Seto, N.O.1    Hayashi, S.2    Tener, G.M.3
  • 41
    • 79952659906 scopus 로고    scopus 로고
    • The free-radical damage theory: accumulating evidence against a simple link of oxidative stress to ageing and lifespan
    • PID: 21290398
    • Speakman JR, Selman C (2011) The free-radical damage theory: accumulating evidence against a simple link of oxidative stress to ageing and lifespan. BioEssays 33:255–259. doi:10.1002/bies.201000132
    • (2011) BioEssays , vol.33 , pp. 255-259
    • Speakman, J.R.1    Selman, C.2
  • 42
    • 0032908347 scopus 로고    scopus 로고
    • FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
    • COI: 1:CAS:528:DyaK1MXhvFOmsw%3D%3D, PID: 9858546
    • Sun J, Tower J (1999) FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol Cell Biol 19:216–228
    • (1999) Mol Cell Biol , vol.19 , pp. 216-228
    • Sun, J.1    Tower, J.2
  • 43
    • 0035989388 scopus 로고    scopus 로고
    • Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
    • COI: 1:CAS:528:DC%2BD38Xlsl2itr0%3D, PID: 12072463
    • Sun J, Folk D, Bradley TJ, Tower J (2002) Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophilamelanogaster. Genetics 161:661–672
    • (2002) Genetics , vol.161 , pp. 661-672
    • Sun, J.1    Folk, D.2    Bradley, T.J.3    Tower, J.4
  • 44
    • 37749024370 scopus 로고    scopus 로고
    • Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
    • COI: 1:CAS:528:DC%2BD1cXhtFyjtL0%3D, PID: 18194654
    • Sykiotis GP, Bohmann D (2008) Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Dev Cell 14:76–85
    • (2008) Dev Cell , vol.14 , pp. 76-85
    • Sykiotis, G.P.1    Bohmann, D.2
  • 45
    • 79956297118 scopus 로고    scopus 로고
    • Coordinated expression of cell death genes regulates neuroblast apoptosis
    • COI: 1:CAS:528:DC%2BC3MXosVSlt7k%3D
    • Tan Y, Yamada-Mabuchiet M, Arya A et al (2011) Coordinated expression of cell death genes regulates neuroblast apoptosis. Development (Cambridge, England) 138:2197–2206
    • (2011) Development (Cambridge, England) , vol.138 , pp. 2197-2206
    • Tan, Y.1    Yamada-Mabuchiet, M.2    Arya, A.3
  • 46
    • 77955379588 scopus 로고    scopus 로고
    • Increased apoptosis of myoblasts in Drosophila model for the Walker–Warburg syndrome
    • PID: 20644630
    • Ueyama M, Akimoto Y, Ichimiya T, Ueda R, Kawakami H, Aigaki T, Nishihara S (2010) Increased apoptosis of myoblasts in Drosophila model for the Walker–Warburg syndrome. PLoS One 5:e11557. doi:10.1371/journal.pone.0011557
    • (2010) PLoS One , vol.5 , pp. e11557
    • Ueyama, M.1    Akimoto, Y.2    Ichimiya, T.3    Ueda, R.4    Kawakami, H.5    Aigaki, T.6    Nishihara, S.7
  • 47
    • 61449184625 scopus 로고    scopus 로고
    • Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans
    • PID: 19197346
    • Van Raamsdonk JM, Hekimi S (2009) Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. PLoS Genet 5:e1000361. doi:10.1371/journal.pgen.1000361
    • (2009) PLoS Genet , vol.5 , pp. e1000361
    • Van Raamsdonk, J.M.1    Hekimi, S.2
  • 48
    • 0036667555 scopus 로고    scopus 로고
    • Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
    • COI: 1:CAS:528:DC%2BD38Xlt12kur8%3D, PID: 12126755
    • Zelko IN, Mariani TJ, Folz RJ (2002) Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 33:337–349
    • (2002) Free Radic Biol Med , vol.33 , pp. 337-349
    • Zelko, I.N.1    Mariani, T.J.2    Folz, R.J.3
  • 49
    • 0033825627 scopus 로고    scopus 로고
    • Oxidative stress and genetics in the pathogenesis of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3cXmtVGntbk%3D, PID: 10964596
    • Zhang Y, Dawson VL, Dawson TM (2000) Oxidative stress and genetics in the pathogenesis of Parkinson’s disease. Neurobiol Dis 7:240–250
    • (2000) Neurobiol Dis , vol.7 , pp. 240-250
    • Zhang, Y.1    Dawson, V.L.2    Dawson, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.