-
1
-
-
0001536516
-
The action of certain esters and ethers of choline, and their relation to muscarine
-
Dale H. The action of certain esters and ethers of choline, and their relation to muscarine. J. Pharmacol. Exp. Ther. 1914, 6:147-190.
-
(1914)
J. Pharmacol. Exp. Ther.
, vol.6
, pp. 147-190
-
-
Dale, H.1
-
2
-
-
9644295236
-
Über humorale Übertragbarkeit der Herznervenwirkung. X. Mitteilung
-
(German)
-
Loewi O., Navratil E. Über humorale Übertragbarkeit der Herznervenwirkung. X. Mitteilung. Pflugers Arch. 1926, 214:678-688. (in German).
-
(1926)
Pflugers Arch.
, vol.214
, pp. 678-688
-
-
Loewi, O.1
Navratil, E.2
-
3
-
-
77952692954
-
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
-
Changeux J.P. Nicotine addiction and nicotinic receptors: lessons from genetically modified mice. Nat. Rev. Neurosci. 2010, 11:389-401.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 389-401
-
-
Changeux, J.P.1
-
4
-
-
34547111135
-
Agents acting at the neuromuscular junction and autonomic ganglia
-
McGraw-Hill, L.L. Brunton (Ed.)
-
Taylor P. Agents acting at the neuromuscular junction and autonomic ganglia. Goodman and Gilman's the Pharmacological Basis of Therapeutics 2006, 217-236. McGraw-Hill. 11th edn. L.L. Brunton (Ed.).
-
(2006)
Goodman and Gilman's the Pharmacological Basis of Therapeutics
, pp. 217-236
-
-
Taylor, P.1
-
5
-
-
84878984984
-
Mesolimbic dopamine and habenulo-interpeduncular pathways in nicotine withdrawal
-
Dani J.A., De Biasi M. Mesolimbic dopamine and habenulo-interpeduncular pathways in nicotine withdrawal. Cold Spring Harb. Perspect. Med. 2013, 3:a012138.
-
(2013)
Cold Spring Harb. Perspect. Med.
, vol.3
, pp. a012138
-
-
Dani, J.A.1
De Biasi, M.2
-
6
-
-
84901604202
-
Connections of nicotine to cancer
-
Grando S.A. Connections of nicotine to cancer. Nat. Rev. Cancer 2014, 14:419-429.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 419-429
-
-
Grando, S.A.1
-
7
-
-
84867127593
-
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior
-
Picciotto M.R., et al. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron 2012, 76:116-129.
-
(2012)
Neuron
, vol.76
, pp. 116-129
-
-
Picciotto, M.R.1
-
8
-
-
0037318283
-
Neurobiology of butyrylcholinesterase
-
Darvesh S., et al. Neurobiology of butyrylcholinesterase. Nat. Rev. Neurosci. 2003, 4:131-138.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 131-138
-
-
Darvesh, S.1
-
9
-
-
0035320772
-
Acetylcholinesterase - new roles for an old actor
-
Soreq H., Seidman S. Acetylcholinesterase - new roles for an old actor. Nat. Rev. Neurosci. 2001, 2:294-302.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 294-302
-
-
Soreq, H.1
Seidman, S.2
-
10
-
-
84883711652
-
Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex
-
Kolisnyk B., et al. Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex. J. Neurosci. 2013, 33:14908-14920.
-
(2013)
J. Neurosci.
, vol.33
, pp. 14908-14920
-
-
Kolisnyk, B.1
-
11
-
-
58249113980
-
Mammalian nicotinic acetylcholine receptors: from structure to function
-
Albuquerque E.X., et al. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev. 2009, 89:73-120.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 73-120
-
-
Albuquerque, E.X.1
-
12
-
-
84872800015
-
Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors
-
Ruiz de Azua I., et al. Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors. Life Sci. 2012, 91:986-991.
-
(2012)
Life Sci.
, vol.91
, pp. 986-991
-
-
Ruiz de Azua, I.1
-
13
-
-
0034004554
-
Identification and characterization of the high-affinity choline transporter
-
Okuda T., et al. Identification and characterization of the high-affinity choline transporter. Nat. Neurosci. 2000, 3:120-125.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 120-125
-
-
Okuda, T.1
-
14
-
-
84924369505
-
Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells
-
Moussaieff A., et al. Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells. Cell Metab. 2015, 21:392-402.
-
(2015)
Cell Metab.
, vol.21
, pp. 392-402
-
-
Moussaieff, A.1
-
15
-
-
84903294091
-
Identification of distinct ChAT neurons and activity-dependent control of postnatal SVZ neurogenesis
-
Paez-Gonzalez P., et al. Identification of distinct ChAT neurons and activity-dependent control of postnatal SVZ neurogenesis. Nat. Neurosci. 2014, 17:934-942.
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 934-942
-
-
Paez-Gonzalez, P.1
-
16
-
-
84910092406
-
IDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging
-
Renier N., et al. iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell 2014, 159:896-910.
-
(2014)
Cell
, vol.159
, pp. 896-910
-
-
Renier, N.1
-
17
-
-
84901313542
-
Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes
-
Cho H.H., et al. Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS Genet. 2014, 10:e1004280.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004280
-
-
Cho, H.H.1
-
18
-
-
84879294704
-
Tlx3 controls cholinergic transmitter and peptide phenotypes in a subset of prenatal sympathetic neurons
-
Huang T., et al. Tlx3 controls cholinergic transmitter and peptide phenotypes in a subset of prenatal sympathetic neurons. J. Neurosci. 2013, 33:10667-10675.
-
(2013)
J. Neurosci.
, vol.33
, pp. 10667-10675
-
-
Huang, T.1
-
19
-
-
84859195359
-
Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system
-
Jensen M., et al. Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system. Cell 2012, 149:173-187.
-
(2012)
Cell
, vol.149
, pp. 173-187
-
-
Jensen, M.1
-
20
-
-
84910019860
-
Optogenetic studies of nicotinic contributions to cholinergic signaling in the central nervous system
-
Jiang L., et al. Optogenetic studies of nicotinic contributions to cholinergic signaling in the central nervous system. Rev. Neurosci. 2014, 25:755-771.
-
(2014)
Rev. Neurosci.
, vol.25
, pp. 755-771
-
-
Jiang, L.1
-
21
-
-
78649442213
-
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex
-
Morishita H., et al. Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science 2010, 330:1238-1240.
-
(2010)
Science
, vol.330
, pp. 1238-1240
-
-
Morishita, H.1
-
22
-
-
84867711270
-
The ly-6 protein, Lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium
-
Fu X.W., et al. The ly-6 protein, Lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012, 303:L661-L668.
-
(2012)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.303
, pp. L661-L668
-
-
Fu, X.W.1
-
23
-
-
84865791576
-
Cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity
-
Gu Z., et al. Cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity. J. Neurosci. 2012, 32:12337-12348.
-
(2012)
J. Neurosci.
, vol.32
, pp. 12337-12348
-
-
Gu, Z.1
-
24
-
-
84857494906
-
Astrocytes mediate in vivo cholinergic-induced synaptic plasticity
-
Navarrete M., et al. Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol. 2012, 10:e1001259.
-
(2012)
PLoS Biol.
, vol.10
, pp. e1001259
-
-
Navarrete, M.1
-
25
-
-
84887649697
-
A cholinergic trigger drives learning-induced plasticity at hippocampal synapses
-
Mitsushima D., et al. A cholinergic trigger drives learning-induced plasticity at hippocampal synapses. Nat. Commun. 2013, 4:2760.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2760
-
-
Mitsushima, D.1
-
26
-
-
83055160837
-
Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo
-
Takata N., et al. Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo. J. Neurosci. 2011, 31:18155-18165.
-
(2011)
J. Neurosci.
, vol.31
, pp. 18155-18165
-
-
Takata, N.1
-
27
-
-
40749093330
-
Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders
-
Michalk A., et al. Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders. Am. J. Hum. Genet. 2008, 82:464-476.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 464-476
-
-
Michalk, A.1
-
28
-
-
70349565939
-
Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis
-
Sabatelli M., et al. Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis. Hum. Mol. Genet. 2009, 18:3997-4006.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3997-4006
-
-
Sabatelli, M.1
-
29
-
-
84863422091
-
Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA
-
Sciamanna G., et al. Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA. Neurobiol. Dis. 2012, 47:416-427.
-
(2012)
Neurobiol. Dis.
, vol.47
, pp. 416-427
-
-
Sciamanna, G.1
-
30
-
-
33749459915
-
CHRND mutation causes a congenital myasthenic syndrome by impairing co-clustering of the acetylcholine receptor with rapsyn
-
Muller J.S., et al. CHRND mutation causes a congenital myasthenic syndrome by impairing co-clustering of the acetylcholine receptor with rapsyn. Brain 2006, 129:2784-2793.
-
(2006)
Brain
, vol.129
, pp. 2784-2793
-
-
Muller, J.S.1
-
31
-
-
84863539303
-
Myasthenic syndrome AChR alpha C-loop mutant disrupts initiation of channel gating
-
Shen X.M., et al. Myasthenic syndrome AChR alpha C-loop mutant disrupts initiation of channel gating. J. Clin. Invest. 2012, 122:2613-2621.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2613-2621
-
-
Shen, X.M.1
-
32
-
-
84905195127
-
Disposed to distraction: genetic variation in the cholinergic system influences distractibility but not time-on-task effects
-
Berry A.S., et al. Disposed to distraction: genetic variation in the cholinergic system influences distractibility but not time-on-task effects. J. Cogn. Neurosci. 2014, 26:1981-1991.
-
(2014)
J. Cogn. Neurosci.
, vol.26
, pp. 1981-1991
-
-
Berry, A.S.1
-
33
-
-
80052969033
-
Choline transporter gene variation is associated with attention-deficit hyperactivity disorder
-
English B.A., et al. Choline transporter gene variation is associated with attention-deficit hyperactivity disorder. J. Neurodev. Disord. 2009, 1:252-263.
-
(2009)
J. Neurodev. Disord.
, vol.1
, pp. 252-263
-
-
English, B.A.1
-
34
-
-
33750481892
-
Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function
-
Neumann S.A., et al. Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function. Biol. Psychiatry 2006, 60:1155-1162.
-
(2006)
Biol. Psychiatry
, vol.60
, pp. 1155-1162
-
-
Neumann, S.A.1
-
35
-
-
84863821582
-
Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons
-
Threlfell S., et al. Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons. Neuron 2012, 75:58-64.
-
(2012)
Neuron
, vol.75
, pp. 58-64
-
-
Threlfell, S.1
-
36
-
-
84864314299
-
Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing
-
Cachope R., et al. Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing. Cell Rep. 2012, 2:33-41.
-
(2012)
Cell Rep.
, vol.2
, pp. 33-41
-
-
Cachope, R.1
-
37
-
-
84896732524
-
Dopamine neurons control striatal cholinergic neurons via regionally heterogeneous dopamine and glutamate signaling
-
Chuhma N., et al. Dopamine neurons control striatal cholinergic neurons via regionally heterogeneous dopamine and glutamate signaling. Neuron 2014, 81:901-912.
-
(2014)
Neuron
, vol.81
, pp. 901-912
-
-
Chuhma, N.1
-
38
-
-
84906535672
-
Phasic dopaminergic activity exerts fast control of cholinergic interneuron firing via sequential NMDA, D2, and D1 receptor activation
-
Wieland S., et al. Phasic dopaminergic activity exerts fast control of cholinergic interneuron firing via sequential NMDA, D2, and D1 receptor activation. J. Neurosci. 2014, 34:11549-11559.
-
(2014)
J. Neurosci.
, vol.34
, pp. 11549-11559
-
-
Wieland, S.1
-
39
-
-
84880344454
-
Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
-
Yang Y., et al. Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:12078-12083.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 12078-12083
-
-
Yang, Y.1
-
40
-
-
84874506923
-
Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior
-
Mineur Y.S., et al. Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:3573-3578.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 3573-3578
-
-
Mineur, Y.S.1
-
41
-
-
84896549341
-
SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission
-
Wu M., et al. SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission. Curr. Biol. 2014, 24:621-629.
-
(2014)
Curr. Biol.
, vol.24
, pp. 621-629
-
-
Wu, M.1
-
42
-
-
84885381952
-
1914G variant of BCHE gene associated with enzyme activity, obesity and triglyceride levels
-
Lima J.K., et al. 1914G variant of BCHE gene associated with enzyme activity, obesity and triglyceride levels. Gene 2013, 532:24-26.
-
(2013)
Gene
, vol.532
, pp. 24-26
-
-
Lima, J.K.1
-
43
-
-
80053593864
-
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit
-
Rosas-Ballina M., et al. Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science 2011, 334:98-101.
-
(2011)
Science
, vol.334
, pp. 98-101
-
-
Rosas-Ballina, M.1
-
44
-
-
71749084011
-
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase
-
Shaked I., et al. MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity 2009, 31:965-973.
-
(2009)
Immunity
, vol.31
, pp. 965-973
-
-
Shaked, I.1
-
45
-
-
33745712914
-
The sympathetic control of blood pressure
-
Guyenet P.G. The sympathetic control of blood pressure. Nat. Rev. Neurosci. 2006, 7:335-346.
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 335-346
-
-
Guyenet, P.G.1
-
46
-
-
33846552537
-
Reduced nicotinic receptor function in sympathetic ganglia is responsible for the hypothermia in the acetylcholinesterase knockout mouse
-
Sun M., et al. Reduced nicotinic receptor function in sympathetic ganglia is responsible for the hypothermia in the acetylcholinesterase knockout mouse. J. Physiol. 2007, 578:751-764.
-
(2007)
J. Physiol.
, vol.578
, pp. 751-764
-
-
Sun, M.1
-
47
-
-
0038282995
-
The pharmacology of nitric oxide in the peripheral nervous system of blood vessels
-
Toda N., Okamura T. The pharmacology of nitric oxide in the peripheral nervous system of blood vessels. Pharmacol. Rev. 2003, 55:271-324.
-
(2003)
Pharmacol. Rev.
, vol.55
, pp. 271-324
-
-
Toda, N.1
Okamura, T.2
-
48
-
-
84893655220
-
+ dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity
-
+ dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity. J. Neuroimmunol. 2014, 267:43-49.
-
(2014)
J. Neuroimmunol.
, vol.267
, pp. 43-49
-
-
Fujii, T.1
-
49
-
-
84885948423
-
Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis
-
Song P., et al. Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis. J. Neurochem. 2013, 126:451-461.
-
(2013)
J. Neurochem.
, vol.126
, pp. 451-461
-
-
Song, P.1
-
50
-
-
77957914369
-
Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE
-
Howard T.D., et al. Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. Environ. Health Perspect. 2010, 118:1395-1399.
-
(2010)
Environ. Health Perspect.
, vol.118
, pp. 1395-1399
-
-
Howard, T.D.1
-
51
-
-
0032574973
-
Acute stress facilitates long-lasting changes in cholinergic gene expression
-
Kaufer D., et al. Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature 1998, 393:373-377.
-
(1998)
Nature
, vol.393
, pp. 373-377
-
-
Kaufer, D.1
-
52
-
-
0025778840
-
Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein
-
Sussman J.L., et al. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science 1991, 253:872-879.
-
(1991)
Science
, vol.253
, pp. 872-879
-
-
Sussman, J.L.1
-
53
-
-
70350571641
-
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
-
Hibbs R.E., et al. Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor. EMBO J. 2009, 28:3040-3051.
-
(2009)
EMBO J.
, vol.28
, pp. 3040-3051
-
-
Hibbs, R.E.1
-
54
-
-
84455188824
-
Choline phosphorylation and regulation of transcription of choline kinase alpha in hypoxia
-
Bansal A., et al. Choline phosphorylation and regulation of transcription of choline kinase alpha in hypoxia. J. Lipid Res. 2012, 53:149-157.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 149-157
-
-
Bansal, A.1
-
55
-
-
84876935461
-
Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2)
-
Zhou G., et al. Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2). J. Biol. Chem. 2013, 288:11940-11948.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 11940-11948
-
-
Zhou, G.1
-
56
-
-
84893182785
-
Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption
-
Slimak M.A., et al. Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption. Front. Hum. Neurosci. 2014, 8:12.
-
(2014)
Front. Hum. Neurosci.
, vol.8
, pp. 12
-
-
Slimak, M.A.1
-
57
-
-
84866354794
-
The CHRNA5-A3-B4 gene cluster in nicotine addiction
-
Berrettini W.H., Doyle G.A. The CHRNA5-A3-B4 gene cluster in nicotine addiction. Mol. Psychiatry 2012, 17:856-866.
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 856-866
-
-
Berrettini, W.H.1
Doyle, G.A.2
-
58
-
-
79953246461
-
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake
-
Fowler C.D., et al. Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature 2011, 471:597-601.
-
(2011)
Nature
, vol.471
, pp. 597-601
-
-
Fowler, C.D.1
-
59
-
-
70349659834
-
Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions
-
Greenbaum L., Lerer B. Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions. Mol. Psychiatry 2009, 14:912-945.
-
(2009)
Mol. Psychiatry
, vol.14
, pp. 912-945
-
-
Greenbaum, L.1
Lerer, B.2
-
60
-
-
65349161502
-
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
-
Wang J.C., et al. Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Mol. Psychiatry 2009, 14:501-510.
-
(2009)
Mol. Psychiatry
, vol.14
, pp. 501-510
-
-
Wang, J.C.1
-
61
-
-
79955658475
-
Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula
-
Frahm S., et al. Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula. Neuron 2011, 70:522-535.
-
(2011)
Neuron
, vol.70
, pp. 522-535
-
-
Frahm, S.1
-
62
-
-
84891390520
-
Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors
-
Henderson B.J., et al. Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors. J. Gen. Physiol. 2014, 143:51-66.
-
(2014)
J. Gen. Physiol.
, vol.143
, pp. 51-66
-
-
Henderson, B.J.1
-
63
-
-
84890125171
-
Alzheimer disease therapy - moving from amyloid-β to Tau
-
Giacobini E., Gold G. Alzheimer disease therapy - moving from amyloid-β to Tau. Nat. Rev. Neurol. 2013, 9:677-686.
-
(2013)
Nat. Rev. Neurol.
, vol.9
, pp. 677-686
-
-
Giacobini, E.1
Gold, G.2
-
64
-
-
84924041785
-
Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study
-
Gray S.L., et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. JAMA Intern. Med. 2015, 175:401-407.
-
(2015)
JAMA Intern. Med.
, vol.175
, pp. 401-407
-
-
Gray, S.L.1
-
65
-
-
0034711312
-
Is RE1/NRSE a common cis-regulatory sequence for ChAT and VAChT genes?
-
De Gois S., et al. Is RE1/NRSE a common cis-regulatory sequence for ChAT and VAChT genes?. J. Biol. Chem. 2000, 275:36683-36690.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36683-36690
-
-
De Gois, S.1
-
66
-
-
84871822255
-
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4
-
Sailaja B.S., et al. Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E3687-E3695.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. E3687-E3695
-
-
Sailaja, B.S.1
-
67
-
-
33645988822
-
Virtues and woes of AChE alternative splicing in stress-related neuropathologies
-
Meshorer E., Soreq H. Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends Neurosci. 2006, 29:216-224.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 216-224
-
-
Meshorer, E.1
Soreq, H.2
-
68
-
-
84893675797
-
Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders
-
Nadorp B., Soreq H. Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders. Front. Mol. Neurosci. 2014, 7:9.
-
(2014)
Front. Mol. Neurosci.
, vol.7
, pp. 9
-
-
Nadorp, B.1
Soreq, H.2
-
69
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
70
-
-
84924388328
-
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs
-
Londin E., et al. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Proc. Natl. Acad. Sci. U.S.A. 2015, 112:E1106-E1115.
-
(2015)
Proc. Natl. Acad. Sci. U.S.A.
, vol.112
, pp. E1106-E1115
-
-
Londin, E.1
-
71
-
-
84905645822
-
Competing targets of microRNA-608 affect anxiety and hypertension
-
Hanin G., et al. Competing targets of microRNA-608 affect anxiety and hypertension. Hum. Mol. Genet. 2014, 23:4569-4580.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 4569-4580
-
-
Hanin, G.1
-
72
-
-
84899513644
-
Global coevolution of human microRNAs and their target genes
-
Barbash S., et al. Global coevolution of human microRNAs and their target genes. Mol. Biol. Evol. 2014, 31:1237-1247.
-
(2014)
Mol. Biol. Evol.
, vol.31
, pp. 1237-1247
-
-
Barbash, S.1
-
73
-
-
84884959481
-
Alteration of the microRNA network during the progression of Alzheimer's disease
-
Lau P., et al. Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol. Med. 2013, 5:1613-1634.
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 1613-1634
-
-
Lau, P.1
-
74
-
-
84872293448
-
Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target
-
Shaltiel G., et al. Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target. Brain Struct. Funct. 2013, 218:59-72.
-
(2013)
Brain Struct. Funct.
, vol.218
, pp. 59-72
-
-
Shaltiel, G.1
-
75
-
-
84856696593
-
Immune cells exploit a neural circuit to enter the CNS
-
Tracey K.J. Immune cells exploit a neural circuit to enter the CNS. Cell 2012, 148:392-394.
-
(2012)
Cell
, vol.148
, pp. 392-394
-
-
Tracey, K.J.1
-
76
-
-
84879073845
-
MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease
-
Maharshak N., et al. MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflamm. Bowel Dis. 2013, 19:1346-1353.
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 1346-1353
-
-
Maharshak, N.1
-
77
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
The Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
78
-
-
79952811366
-
Quantum dot labeling of butyrylcholinesterase maintains substrate and inhibitor interactions and cell adherence features
-
Waiskopf N., et al. Quantum dot labeling of butyrylcholinesterase maintains substrate and inhibitor interactions and cell adherence features. ACS Chem. Neurosci. 2011, 2:141-150.
-
(2011)
ACS Chem. Neurosci.
, vol.2
, pp. 141-150
-
-
Waiskopf, N.1
-
79
-
-
80053563273
-
NeurimmiRs: microRNAs in the neuroimmune interface
-
Soreq H., Wolf Y. NeurimmiRs: microRNAs in the neuroimmune interface. Trends Mol. Med. 2011, 17:548-555.
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 548-555
-
-
Soreq, H.1
Wolf, Y.2
-
80
-
-
0037220723
-
Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice
-
Anagnostaras S.G., et al. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat. Neurosci. 2003, 6:51-58.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 51-58
-
-
Anagnostaras, S.G.1
-
81
-
-
0030708762
-
Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice
-
Hamilton S.E., et al. Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:13311-13316.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13311-13316
-
-
Hamilton, S.E.1
-
82
-
-
84866729462
-
Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease
-
Goldberg J.A., et al. Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease. Nat. Neurosci. 2012, 15:1414-1421.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1414-1421
-
-
Goldberg, J.A.1
-
83
-
-
0037122918
-
PRiMA: the membrane anchor of acetylcholinesterase in the brain
-
Perrier A.L., et al. PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron 2002, 33:275-285.
-
(2002)
Neuron
, vol.33
, pp. 275-285
-
-
Perrier, A.L.1
-
84
-
-
45249107304
-
Further observations in congenital myasthenic syndromes
-
Engel A.G., et al. Further observations in congenital myasthenic syndromes. Ann. N. Y. Acad. Sci. 2008, 1132:104-113.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1132
, pp. 104-113
-
-
Engel, A.G.1
-
85
-
-
0027368530
-
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase
-
Harel M., et al. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:9031-9035.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 9031-9035
-
-
Harel, M.1
-
86
-
-
41949132813
-
Acetylcholinesterase inhibitors and Gulf War illnesses
-
Golomb B.A. Acetylcholinesterase inhibitors and Gulf War illnesses. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:4295-4300.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 4295-4300
-
-
Golomb, B.A.1
-
87
-
-
0029863697
-
Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme
-
Inestrosa N.C., et al. Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 1996, 16:881-891.
-
(1996)
Neuron
, vol.16
, pp. 881-891
-
-
Inestrosa, N.C.1
-
88
-
-
37549022563
-
Changes in readthrough acetylcholinesterase expression modulate amyloid-β pathology
-
Berson A., et al. Changes in readthrough acetylcholinesterase expression modulate amyloid-β pathology. Brain 2008, 131:109-119.
-
(2008)
Brain
, vol.131
, pp. 109-119
-
-
Berson, A.1
-
89
-
-
18644371374
-
The k variant of the butyrylcholinesterase gene is associated with reduced phosphorylation of Tau in dementia patients
-
Ballard C., et al. The k variant of the butyrylcholinesterase gene is associated with reduced phosphorylation of Tau in dementia patients. Dement. Geriatr. Cogn. Disord. 2005, 19:357-360.
-
(2005)
Dement. Geriatr. Cogn. Disord.
, vol.19
, pp. 357-360
-
-
Ballard, C.1
-
90
-
-
84871567801
-
Further developments with antisense treatment for myasthenia gravis
-
Sussman J., et al. Further developments with antisense treatment for myasthenia gravis. Ann. N. Y. Acad. Sci. 2012, 1275:13-16.
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1275
, pp. 13-16
-
-
Sussman, J.1
-
91
-
-
84857167112
-
Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFκB pathway
-
Zimmerman G., et al. Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFκB pathway. Transl. Psychiatry 2012, 2:e78.
-
(2012)
Transl. Psychiatry
, vol.2
, pp. e78
-
-
Zimmerman, G.1
-
92
-
-
84946496970
-
Gut feeling: microRNA discriminators of the intestinal TLR9-cholinergic links
-
Published online May 20, 2015
-
Nadorp B., Soreq H. Gut feeling: microRNA discriminators of the intestinal TLR9-cholinergic links. Int. Immunopharmacol. 2015, Published online May 20, 2015. 10.1016/j.intimp.2015.04.058.
-
(2015)
Int. Immunopharmacol.
-
-
Nadorp, B.1
Soreq, H.2
-
93
-
-
79960891073
-
Anti-inflammatory effects of nicotine in obesity and ulcerative colitis
-
Lakhan S.E., Kirchgessner A. Anti-inflammatory effects of nicotine in obesity and ulcerative colitis. J. Transl. Med. 2011, 9:129.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 129
-
-
Lakhan, S.E.1
Kirchgessner, A.2
-
94
-
-
84872931968
-
The protective effect of PNU-282987, a selective α7 nicotinic acetylcholine receptor agonist, on the hepatic ischemia-reperfusion injury is associated with the inhibition of high-mobility group box 1 protein expression and nuclear factor κB activation in mice
-
Li F., et al. The protective effect of PNU-282987, a selective α7 nicotinic acetylcholine receptor agonist, on the hepatic ischemia-reperfusion injury is associated with the inhibition of high-mobility group box 1 protein expression and nuclear factor κB activation in mice. Shock 2013, 39:197-203.
-
(2013)
Shock
, vol.39
, pp. 197-203
-
-
Li, F.1
-
95
-
-
84871838396
-
Retooling spare parts: gene duplication and cognition
-
Belgard T.G., Geschwind D.H. Retooling spare parts: gene duplication and cognition. Nat. Neurosci. 2013, 16:6-8.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 6-8
-
-
Belgard, T.G.1
Geschwind, D.H.2
-
96
-
-
84905582433
-
Most genetic risk for autism resides with common variation
-
Gaugler T., et al. Most genetic risk for autism resides with common variation. Nat. Genet. 2014, 46:881-885.
-
(2014)
Nat. Genet.
, vol.46
, pp. 881-885
-
-
Gaugler, T.1
-
97
-
-
84893919352
-
De novo mutations in schizophrenia implicate synaptic networks
-
Fromer M., et al. De novo mutations in schizophrenia implicate synaptic networks. Nature 2014, 506:179-184.
-
(2014)
Nature
, vol.506
, pp. 179-184
-
-
Fromer, M.1
-
98
-
-
84911476411
-
CircRNA biogenesis competes with pre-mRNA splicing
-
Ashwal-Fluss R., et al. circRNA biogenesis competes with pre-mRNA splicing. Mol. Cell 2014, 56:55-66.
-
(2014)
Mol. Cell
, vol.56
, pp. 55-66
-
-
Ashwal-Fluss, R.1
-
99
-
-
84924330592
-
Competition between target sites of regulators shapes post-transcriptional gene regulation
-
Jens M., Rajewsky N. Competition between target sites of regulators shapes post-transcriptional gene regulation. Nat. Rev. Genet. 2015, 16:113-126.
-
(2015)
Nat. Rev. Genet.
, vol.16
, pp. 113-126
-
-
Jens, M.1
Rajewsky, N.2
-
100
-
-
84880118099
-
Proteomics screen to reveal molecular changes mediated by C722G missense mutation in CHRM2 gene
-
Hou D., et al. Proteomics screen to reveal molecular changes mediated by C722G missense mutation in CHRM2 gene. J. Proteomics 2013, 89:39-50.
-
(2013)
J. Proteomics
, vol.89
, pp. 39-50
-
-
Hou, D.1
|