메뉴 건너뛰기




Volumn 47, Issue 3, 2012, Pages 416-427

Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA

Author keywords

Acetylcholine; Cholinergic interneuron; Conditional knock out; Dystonia; DYT1; Electrophysiology; TorsinA

Indexed keywords

ACETYLCHOLINE; DOPAMINE; DOPAMINE 2 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUTANT PROTEIN; TORSIN A PROTEIN; UNCLASSIFIED DRUG;

EID: 84863422091     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.04.015     Document Type: Article
Times cited : (71)

References (55)
  • 1
    • 78650149431 scopus 로고    scopus 로고
    • EFNS guidelines on diagnosis and treatment of primary dystonias
    • Albanese A., et al. EFNS guidelines on diagnosis and treatment of primary dystonias. Eur. J. Neurol. 2011, 18:5-18.
    • (2011) Eur. J. Neurol. , vol.18 , pp. 5-18
    • Albanese, A.1
  • 2
    • 0032754787 scopus 로고    scopus 로고
    • Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain
    • Augood S.J., et al. Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain. Ann. Neurol. 1999, 46:761-769.
    • (1999) Ann. Neurol. , vol.46 , pp. 761-769
    • Augood, S.J.1
  • 3
    • 0142026884 scopus 로고    scopus 로고
    • Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain
    • Augood S., et al. Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain. Brain Res. 2003, 986:12-21.
    • (2003) Brain Res. , vol.986 , pp. 12-21
    • Augood, S.1
  • 4
    • 34447303772 scopus 로고    scopus 로고
    • Dopamine release is impaired in a mouse model of DYT1 dystonia
    • Balcioglu A., et al. Dopamine release is impaired in a mouse model of DYT1 dystonia. J. Neurochem. 2007, 102:783-788.
    • (2007) J. Neurochem. , vol.102 , pp. 783-788
    • Balcioglu, A.1
  • 5
    • 0034668915 scopus 로고    scopus 로고
    • Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons
    • Bennett B.D., et al. Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons. J. Neurosci. 2000, 20:8493-8503.
    • (2000) J. Neurosci. , vol.20 , pp. 8493-8503
    • Bennett, B.D.1
  • 6
    • 23644432048 scopus 로고    scopus 로고
    • Modulatory action of metabotropic glutamate receptor (mGluR) 5 on mGluR1 function in striatal cholinergic interneurons
    • Bonsi P., et al. Modulatory action of metabotropic glutamate receptor (mGluR) 5 on mGluR1 function in striatal cholinergic interneurons. Neuropharmacology 2005, 49(Suppl. 1):104-113.
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. 1 , pp. 104-113
    • Bonsi, P.1
  • 7
    • 34250191571 scopus 로고    scopus 로고
    • Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors
    • Bonsi P., et al. Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors. Neuropsychopharmacology 2007, 32:1840-1854.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1840-1854
    • Bonsi, P.1
  • 8
    • 0034879921 scopus 로고    scopus 로고
    • TorsinA: movement at many levels
    • Breakefield X., et al. TorsinA: movement at many levels. Neuron 2001, 31:9-12.
    • (2001) Neuron , vol.31 , pp. 9-12
    • Breakefield, X.1
  • 9
    • 39449138688 scopus 로고    scopus 로고
    • The pathophysiological basis of dystonias
    • Breakefield X., et al. The pathophysiological basis of dystonias. Nat. Rev. Neurosci. 2008, 9:222-234.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 222-234
    • Breakefield, X.1
  • 10
    • 0022625203 scopus 로고
    • Torsion dystonia: a double-blind, prospective trial of high-dosage trihexyphenidyl
    • Burke R., et al. Torsion dystonia: a double-blind, prospective trial of high-dosage trihexyphenidyl. Neurology 1986, 36:160-164.
    • (1986) Neurology , vol.36 , pp. 160-164
    • Burke, R.1
  • 11
    • 0032527772 scopus 로고    scopus 로고
    • Muscarinic IPSPs in rat striatal cholinergic interneurones
    • Calabresi P., et al. Muscarinic IPSPs in rat striatal cholinergic interneurones. J. Physiol. 1998, 510(Pt 2):421-427.
    • (1998) J. Physiol. , vol.510 , Issue.PART 2 , pp. 421-427
    • Calabresi, P.1
  • 12
    • 67650718740 scopus 로고    scopus 로고
    • Abnormal structure-function relationships in hereditary dystonia
    • Carbon M., Eidelberg D. Abnormal structure-function relationships in hereditary dystonia. Neuroscience 2009, 164:220-229.
    • (2009) Neuroscience , vol.164 , pp. 220-229
    • Carbon, M.1    Eidelberg, D.2
  • 13
    • 39749188707 scopus 로고    scopus 로고
    • Microstructural white matter changes in primary torsion dystonia
    • Carbon M., et al. Microstructural white matter changes in primary torsion dystonia. Mov. Disord. 2008, 23:234-239.
    • (2008) Mov. Disord. , vol.23 , pp. 234-239
    • Carbon, M.1
  • 14
    • 27744567561 scopus 로고    scopus 로고
    • Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystonia
    • Dang M., et al. Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystonia. Exp. Neurol. 2005, 196:452-463.
    • (2005) Exp. Neurol. , vol.196 , pp. 452-463
    • Dang, M.1
  • 15
    • 33751019482 scopus 로고    scopus 로고
    • Motor deficits and hyperactivity in Dyt1 knockdown mice
    • Dang M., et al. Motor deficits and hyperactivity in Dyt1 knockdown mice. Neurosci. Res. 2006, 56:470-474.
    • (2006) Neurosci. Res. , vol.56 , pp. 470-474
    • Dang, M.1
  • 16
    • 81355146404 scopus 로고    scopus 로고
    • An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 DeltaGAG knock-in mice
    • Dang M.T., et al. An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 DeltaGAG knock-in mice. Behav. Brain Res. 2012, 226:465-472.
    • (2012) Behav. Brain Res. , vol.226 , pp. 465-472
    • Dang, M.T.1
  • 17
    • 14544267529 scopus 로고    scopus 로고
    • Accelerated Barnes maze test in mice for assessment of stress effects on memory
    • Dawood M.Y., et al. Accelerated Barnes maze test in mice for assessment of stress effects on memory. Ann. N. Y. Acad. Sci. 2004, 1032:304-307.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1032 , pp. 304-307
    • Dawood, M.Y.1
  • 18
    • 78149498710 scopus 로고    scopus 로고
    • Characterization of Atp1a3 mutant mice as a model of rapid-onset dystonia with parkinsonism
    • Deandrade M.P., et al. Characterization of Atp1a3 mutant mice as a model of rapid-onset dystonia with parkinsonism. Behav. Brain Res. 2011, 216:659-665.
    • (2011) Behav. Brain Res. , vol.216 , pp. 659-665
    • Deandrade, M.P.1
  • 19
    • 33846437442 scopus 로고    scopus 로고
    • Abnormalities in motor cortical plasticity differentiate manifesting and nonmanifesting DYT1 carriers
    • Edwards M., et al. Abnormalities in motor cortical plasticity differentiate manifesting and nonmanifesting DYT1 carriers. Mov. Disord. 2006, 21:2181-2186.
    • (2006) Mov. Disord. , vol.21 , pp. 2181-2186
    • Edwards, M.1
  • 20
    • 0016905990 scopus 로고
    • Definition of dystonia and classification of the dystonic states
    • Fahn S., Eldridge R. Definition of dystonia and classification of the dystonic states. Adv. Neurol. 1976, 14:1-5.
    • (1976) Adv. Neurol. , vol.14 , pp. 1-5
    • Fahn, S.1    Eldridge, R.2
  • 21
    • 0038123157 scopus 로고    scopus 로고
    • Impaired sequence learning in carriers of the DYT1 dystonia mutation
    • Ghilardi M.F., et al. Impaired sequence learning in carriers of the DYT1 dystonia mutation. Ann. Neurol. 2003, 54:102-109.
    • (2003) Ann. Neurol. , vol.54 , pp. 102-109
    • Ghilardi, M.F.1
  • 22
    • 1642290757 scopus 로고    scopus 로고
    • Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia
    • Gonzalez-Alegre P., Paulson H. Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia. J. Neurosci. 2004, 24:2593-2601.
    • (2004) J. Neurosci. , vol.24 , pp. 2593-2601
    • Gonzalez-Alegre, P.1    Paulson, H.2
  • 23
    • 29144460260 scopus 로고    scopus 로고
    • Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope
    • Goodchild R.E., et al. Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope. Neuron 2005, 48:923-932.
    • (2005) Neuron , vol.48 , pp. 923-932
    • Goodchild, R.E.1
  • 24
    • 65949083775 scopus 로고    scopus 로고
    • TorsinA and dystonia: from nuclear envelope to synapse
    • Granata A., et al. TorsinA and dystonia: from nuclear envelope to synapse. J. Neurochem. 2009, 109:1596-1609.
    • (2009) J. Neurochem. , vol.109 , pp. 1596-1609
    • Granata, A.1
  • 25
    • 34447641630 scopus 로고    scopus 로고
    • Overexpression of human wildtype torsinA and human DeltaGAG torsinA in a transgenic mouse model causes phenotypic abnormalities
    • Grundmann K., et al. Overexpression of human wildtype torsinA and human DeltaGAG torsinA in a transgenic mouse model causes phenotypic abnormalities. Neurobiol. Dis. 2007, 27:190-206.
    • (2007) Neurobiol. Dis. , vol.27 , pp. 190-206
    • Grundmann, K.1
  • 26
    • 70449685575 scopus 로고    scopus 로고
    • Characterization of transgenic mouse lines expressing Cre recombinase in the retina
    • Ivanova E., et al. Characterization of transgenic mouse lines expressing Cre recombinase in the retina. Neuroscience 2010, 165:233-243.
    • (2010) Neuroscience , vol.165 , pp. 233-243
    • Ivanova, E.1
  • 27
    • 18144430546 scopus 로고    scopus 로고
    • Rodent models for dystonia research: characteristics, evaluation, and utility
    • Jinnah H.A., et al. Rodent models for dystonia research: characteristics, evaluation, and utility. Mov. Disord. 2005, 20:283-292.
    • (2005) Mov. Disord. , vol.20 , pp. 283-292
    • Jinnah, H.A.1
  • 28
    • 0023522211 scopus 로고
    • Dopamine acts on D2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta
    • Lacey M.G., et al. Dopamine acts on D2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta. J. Physiol. 1987, 392:397-416.
    • (1987) J. Physiol. , vol.392 , pp. 397-416
    • Lacey, M.G.1
  • 29
    • 28044469874 scopus 로고    scopus 로고
    • K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons
    • Liss B., et al. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat. Neurosci. 2005, 8:1742-1751.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1742-1751
    • Liss, B.1
  • 30
    • 73949140059 scopus 로고    scopus 로고
    • A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
    • Madisen L., et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat. Neurosci. 2010, 13:133-140.
    • (2010) Nat. Neurosci. , vol.13 , pp. 133-140
    • Madisen, L.1
  • 31
    • 71549148437 scopus 로고    scopus 로고
    • Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine
    • Martella G., et al. Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine. Brain 2009, 132:2336-2349.
    • (2009) Brain , vol.132 , pp. 2336-2349
    • Martella, G.1
  • 32
    • 0028931163 scopus 로고
    • Properties of the hyperpolarization-activated cation current Ih in rat midbrain dopaminergic neurons
    • Mercuri N.B., et al. Properties of the hyperpolarization-activated cation current Ih in rat midbrain dopaminergic neurons. Eur. J. Neurosci. 1995, 7:462-469.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 462-469
    • Mercuri, N.B.1
  • 33
    • 0030611615 scopus 로고    scopus 로고
    • Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice
    • Mercuri N.B., et al. Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice. Neuroscience 1997, 79:323-327.
    • (1997) Neuroscience , vol.79 , pp. 323-327
    • Mercuri, N.B.1
  • 34
    • 77952542997 scopus 로고    scopus 로고
    • Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia
    • Napolitano F., et al. Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia. Neurobiol. Dis. 2010, 38:434-445.
    • (2010) Neurobiol. Dis. , vol.38 , pp. 434-445
    • Napolitano, F.1
  • 35
    • 16944366666 scopus 로고    scopus 로고
    • The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein
    • Ozelius L.J., et al. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat. Genet. 1997, 17:40-48.
    • (1997) Nat. Genet. , vol.17 , pp. 40-48
    • Ozelius, L.J.1
  • 36
    • 77954956971 scopus 로고    scopus 로고
    • Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (DeltaE) TorsinA in transgenic mice
    • Page M.E., et al. Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (DeltaE) TorsinA in transgenic mice. Neurobiol. Dis. 2010, 39:318-326.
    • (2010) Neurobiol. Dis. , vol.39 , pp. 318-326
    • Page, M.E.1
  • 37
    • 67349159339 scopus 로고    scopus 로고
    • Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition
    • Pecho-Vrieseling E., et al. Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature 2009, 459:842-846.
    • (2009) Nature , vol.459 , pp. 842-846
    • Pecho-Vrieseling, E.1
  • 38
    • 0033013554 scopus 로고    scopus 로고
    • 2/glucose deprivation
    • 2/glucose deprivation. J. Neurophysiol. 1999, 81:2508-2516.
    • (1999) J. Neurophysiol. , vol.81 , pp. 2508-2516
    • Pisani, A.1
  • 39
    • 33749984203 scopus 로고    scopus 로고
    • Altered responses to dopaminergic D2 receptor activation and N-type calcium currents in striatal cholinergic interneurons in a mouse model of DYT1 dystonia
    • Pisani A., et al. Altered responses to dopaminergic D2 receptor activation and N-type calcium currents in striatal cholinergic interneurons in a mouse model of DYT1 dystonia. Neurobiol. Dis. 2006, 24:318-325.
    • (2006) Neurobiol. Dis. , vol.24 , pp. 318-325
    • Pisani, A.1
  • 40
    • 0037329443 scopus 로고    scopus 로고
    • TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion
    • Rostasy K., et al. TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion. Neurobiol. Dis. 2003, 12:11-24.
    • (2003) Neurobiol. Dis. , vol.12 , pp. 11-24
    • Rostasy, K.1
  • 41
    • 80052406561 scopus 로고    scopus 로고
    • Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia
    • Sciamanna G., et al. Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia. PLoS One 2011, 6:e24261.
    • (2011) PLoS One , vol.6
    • Sciamanna, G.1
  • 42
    • 20044374519 scopus 로고    scopus 로고
    • Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation
    • Sharma N., et al. Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation. J. Neurosci. 2005, 25:5351-5355.
    • (2005) J. Neurosci. , vol.25 , pp. 5351-5355
    • Sharma, N.1
  • 43
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 1999, 21:70-71.
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 44
    • 79952693973 scopus 로고    scopus 로고
    • Update on the pathology of dystonia
    • Standaert D.G. Update on the pathology of dystonia. Neurobiol. Dis. 2011, 42:148-151.
    • (2011) Neurobiol. Dis. , vol.42 , pp. 148-151
    • Standaert, D.G.1
  • 45
    • 8144230422 scopus 로고    scopus 로고
    • Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant
    • Torres G., et al. Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:15650-15655.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 15650-15655
    • Torres, G.1
  • 46
    • 33644963223 scopus 로고    scopus 로고
    • Developmental patterns of torsinA and torsinB expression
    • Vasudevan A., et al. Developmental patterns of torsinA and torsinB expression. Brain Res. 2006, 1073-1074:139-145.
    • (2006) Brain Res. , pp. 139-145
    • Vasudevan, A.1
  • 47
    • 69749115919 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
    • Wang Z., et al. Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J. Neurosci. 2009, 29:10788-10801.
    • (2009) J. Neurosci. , vol.29 , pp. 10788-10801
    • Wang, Z.1
  • 48
    • 77953264427 scopus 로고    scopus 로고
    • TorsinA and DYT1 dystonia: a synaptopathy?
    • Warner T., et al. TorsinA and DYT1 dystonia: a synaptopathy?. Biochem. Soc. Trans. 2010, 38:452-456.
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 452-456
    • Warner, T.1
  • 49
    • 38849083925 scopus 로고    scopus 로고
    • Motor deficits and hyperactivity in cerebral cortex-specific Dyt1 conditional knockout mice
    • Yokoi F., et al. Motor deficits and hyperactivity in cerebral cortex-specific Dyt1 conditional knockout mice. J. Biochem. 2008, 143:39-47.
    • (2008) J. Biochem. , vol.143 , pp. 39-47
    • Yokoi, F.1
  • 50
    • 80052634773 scopus 로고    scopus 로고
    • Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice
    • Yokoi F., et al. Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice. PLoS One 2011, 6:e24539.
    • (2011) PLoS One , vol.6
    • Yokoi, F.1
  • 51
    • 33750338069 scopus 로고    scopus 로고
    • Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine
    • Zhang L., et al. Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine. Prog. Neuro psychopharmacol. Biol. Psychiatry 2006, 30:1381-1393.
    • (2006) Prog. Neuro psychopharmacol. Biol. Psychiatry , vol.30 , pp. 1381-1393
    • Zhang, L.1
  • 52
    • 34547884686 scopus 로고    scopus 로고
    • Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine
    • Zhang L., et al. Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine. Neuropsychopharmacology 2007, 32:2004-2010.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2004-2010
    • Zhang, L.1
  • 53
    • 41149160099 scopus 로고    scopus 로고
    • Abnormal motor function and dopamine neurotransmission in DYT1 DeltaGAG transgenic mice
    • Zhao Y., et al. Abnormal motor function and dopamine neurotransmission in DYT1 DeltaGAG transgenic mice. Exp. Neurol. 2008, 210:719-730.
    • (2008) Exp. Neurol. , vol.210 , pp. 719-730
    • Zhao, Y.1
  • 54
    • 79952008357 scopus 로고    scopus 로고
    • The DYT1 carrier state increases energy demand in the olivocerebellar network
    • Zhao Y., et al. The DYT1 carrier state increases energy demand in the olivocerebellar network. Neuroscience 2011, 177:183-194.
    • (2011) Neuroscience , vol.177 , pp. 183-194
    • Zhao, Y.1
  • 55
    • 12744279625 scopus 로고    scopus 로고
    • Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1
    • Zucker B., et al. Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Hum. Mol. Genet. 2005, 14:179-189.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 179-189
    • Zucker, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.