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Volumn 29, Issue 1, 2015, Pages 8-14

Gut feeling: MicroRNA discriminators of the intestinal TLR9-cholinergic links

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Intestinal inflammation; MicroRNA; Non neuronal acetylcholine; Toll Like Receptor 9

Indexed keywords

ANTIINFLAMMATORY AGENT; APTAMER; BL 7040; CHOLINESTERASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEN 101; MICRORNA; MICRORNA 129 5P; MICRORNA 132; MICRORNA 186; MICRORNA 200C; NITRIC OXIDE; ODN 1826; ODN 2088; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; ACETYLCHOLINE; ACETYLCHOLINESTERASE; OLIGONUCLEOTIDE; PROTEIN BINDING; TLR9 PROTEIN, MOUSE;

EID: 84946496970     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.04.058     Document Type: Article
Times cited : (15)

References (39)
  • 1
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • R. Medzhitov Origin and physiological roles of inflammation Nature 454 2008 428 435
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 2
    • 84870038215 scopus 로고    scopus 로고
    • The vagus nerve and the inflammatory reflex-linking immunity and metabolism
    • V.A. Pavlov, and K.J. Tracey The vagus nerve and the inflammatory reflex-linking immunity and metabolism Nat. Rev. Endocrinol. 8 2012 743 754
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 743-754
    • Pavlov, V.A.1    Tracey, K.J.2
  • 3
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • S. Vallabhapurapu, and M. Karin Regulation and function of NF-kappaB transcription factors in the immune system Annu. Rev. Immunol. 27 2009 693 733
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 4
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • G.M. Barton, J.C. Kagan, and R. Medzhitov Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA Nat. Immunol. 7 2006 49 56
    • (2006) Nat. Immunol. , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 5
    • 35748964708 scopus 로고    scopus 로고
    • Toll-like receptors 7, 8, and 9: Linking innate immunity to autoimmunity
    • A.M. Krieg, and J. Vollmer Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity Immunol. Rev. 220 2007 251 269
    • (2007) Immunol. Rev. , vol.220 , pp. 251-269
    • Krieg, A.M.1    Vollmer, J.2
  • 6
    • 33751551466 scopus 로고    scopus 로고
    • Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
    • J. Lee, J.H. Mo, K. Katakura, I. Alkalay, A.N. Rucker, Y.T. Liu, and et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells Nat. Cell Biol. 8 2006 1327 1336
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1327-1336
    • Lee, J.1    Mo, J.H.2    Katakura, K.3    Alkalay, I.4    Rucker, A.N.5    Liu, Y.T.6
  • 7
    • 33645841633 scopus 로고    scopus 로고
    • IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9
    • K. Hoshino, T. Sugiyama, M. Matsumoto, T. Tanaka, M. Saito, H. Hemmi, and et al. IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9 Nature 440 2006 949 953
    • (2006) Nature , vol.440 , pp. 949-953
    • Hoshino, K.1    Sugiyama, T.2    Matsumoto, M.3    Tanaka, T.4    Saito, M.5    Hemmi, H.6
  • 8
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • A.M. Krieg Therapeutic potential of Toll-like receptor 9 activation Nat. Rev. Drug Discov. 5 2006 471 484
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 10
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • G. Bonizzi, and M. Karin The two NF-kappaB activation pathways and their role in innate and adaptive immunity Trends Immunol. 25 2004 280 288
    • (2004) Trends Immunol. , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 11
    • 59749097591 scopus 로고    scopus 로고
    • Rel/NF-kappaB family member RelA regulates NK1.1 - To NK1.1 + transition as well as IL-15-induced expansion of NKT cells
    • S. Vallabhapurapu, I. Powolny-Budnicka, M. Riemann, R.M. Schmid, S. Paxian, K. Pfeffer, and et al. Rel/NF-kappaB family member RelA regulates NK1.1 - to NK1.1 + transition as well as IL-15-induced expansion of NKT cells Eur. J. Immunol. 38 2008 3508 3519
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3508-3519
    • Vallabhapurapu, S.1    Powolny-Budnicka, I.2    Riemann, M.3    Schmid, R.M.4    Paxian, S.5    Pfeffer, K.6
  • 12
    • 42149110830 scopus 로고    scopus 로고
    • Control of canonical NF-kappaB activation through the NIK-IKK complex pathway
    • B. Zarnegar, S. Yamazaki, J.Q. He, and G. Cheng Control of canonical NF-kappaB activation through the NIK-IKK complex pathway Proc. Natl. Acad. Sci. U. S. A. 105 2008 3503 3508
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 3503-3508
    • Zarnegar, B.1    Yamazaki, S.2    He, J.Q.3    Cheng, G.4
  • 13
    • 56349164239 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
    • B.J. Zarnegar, Y. Wang, D.J. Mahoney, P.W. Dempsey, H.H. Cheung, J. He, and et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK Nat. Immunol. 9 2008 1371 1378
    • (2008) Nat. Immunol. , vol.9 , pp. 1371-1378
    • Zarnegar, B.J.1    Wang, Y.2    Mahoney, D.J.3    Dempsey, P.W.4    Cheung, H.H.5    He, J.6
  • 14
    • 18244401355 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production
    • Y. Pollak, A. Gilboa, O. Ben-Menachem, T. Ben-Hur, H. Soreq, and R. Yirmiya Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production Ann. Neurol. 57 2005 741 745
    • (2005) Ann. Neurol. , vol.57 , pp. 741-745
    • Pollak, Y.1    Gilboa, A.2    Ben-Menachem, O.3    Ben-Hur, T.4    Soreq, H.5    Yirmiya, R.6
  • 15
    • 33645738965 scopus 로고    scopus 로고
    • Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis
    • M. Pick, C. Perry, T. Lapidot, C. Guimaraes-Sternberg, E. Naparstek, V. Deutsch, and et al. Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis Blood 107 2006 3397 3406
    • (2006) Blood , vol.107 , pp. 3397-3406
    • Pick, M.1    Perry, C.2    Lapidot, T.3    Guimaraes-Sternberg, C.4    Naparstek, E.5    Deutsch, V.6
  • 16
    • 34548863106 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation
    • S.W. Tas, M.J. Vervoordeldonk, N. Hajji, J.H. Schuitemaker, K.F. van der Sluijs, M.J. May, and et al. Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation Blood 110 2007 1540 1549
    • (2007) Blood , vol.110 , pp. 1540-1549
    • Tas, S.W.1    Vervoordeldonk, M.J.2    Hajji, N.3    Schuitemaker, J.H.4    Van Der Sluijs, K.F.5    May, M.J.6
  • 17
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kappaB activation
    • P. Puccetti, and U. Grohmann IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation Nat. Rev. Immunol. 7 2007 817 823
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 18
    • 71749084011 scopus 로고    scopus 로고
    • MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase
    • I. Shaked, A. Meerson, Y. Wolf, R. Avni, D. Greenberg, A. Gilboa-Geffen, and et al. MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase Immunity 31 2009 965 973
    • (2009) Immunity , vol.31 , pp. 965-973
    • Shaked, I.1    Meerson, A.2    Wolf, Y.3    Avni, R.4    Greenberg, D.5    Gilboa-Geffen, A.6
  • 19
    • 3142755799 scopus 로고    scopus 로고
    • Combinatorial complexity of 5′ alternative acetylcholinesterase transcripts and protein products
    • E. Meshorer, D. Toiber, D. Zurel, I. Sahly, A. Dori, E. Cagnano, and et al. Combinatorial complexity of 5′ alternative acetylcholinesterase transcripts and protein products J. Biol. Chem. 279 2004 29740 29751
    • (2004) J. Biol. Chem. , vol.279 , pp. 29740-29751
    • Meshorer, E.1    Toiber, D.2    Zurel, D.3    Sahly, I.4    Dori, A.5    Cagnano, E.6
  • 21
    • 84857167112 scopus 로고    scopus 로고
    • Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFkappaB pathway
    • G. Zimmerman, G. Shaltiel, S. Barbash, J. Cohen, C.J. Gasho, S. Shenhar-Tsarfaty, and et al. Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFkappaB pathway Transl. Psychiatry 2 2012 e78
    • (2012) Transl. Psychiatry , vol.2 , pp. e78
    • Zimmerman, G.1    Shaltiel, G.2    Barbash, S.3    Cohen, J.4    Gasho, C.J.5    Shenhar-Tsarfaty, S.6
  • 22
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • K.J. Tracey The inflammatory reflex Nature 420 2002 853 859
    • (2002) Nature , vol.420 , pp. 853-859
    • Tracey, K.J.1
  • 23
    • 0035320772 scopus 로고    scopus 로고
    • Acetylcholinesterase - New roles for an old actor
    • H. Soreq, and S. Seidman Acetylcholinesterase - new roles for an old actor Nat. Rev. Neurosci. 2 2001 294 302
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 294-302
    • Soreq, H.1    Seidman, S.2
  • 24
    • 53349164200 scopus 로고    scopus 로고
    • Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
    • J.A. Hall, N. Bouladoux, C.M. Sun, E.A. Wohlfert, R.B. Blank, Q. Zhu, and et al. Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses Immunity 29 2008 637 649
    • (2008) Immunity , vol.29 , pp. 637-649
    • Hall, J.A.1    Bouladoux, N.2    Sun, C.M.3    Wohlfert, E.A.4    Blank, R.B.5    Zhu, Q.6
  • 25
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 26
    • 84893675797 scopus 로고    scopus 로고
    • Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders
    • B. Nadorp, and H. Soreq Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders Front. Mol. Neurosci. 7 2014 9
    • (2014) Front. Mol. Neurosci. , vol.7 , pp. 9
    • Nadorp, B.1    Soreq, H.2
  • 27
    • 23844441866 scopus 로고    scopus 로고
    • RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons
    • T. Evron, L.B. Moyal-Segal, N. Lamm, A. Geffen, and H. Soreq RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons Neurodegener. Dis. 2 2005 16 27
    • (2005) Neurodegener. Dis. , vol.2 , pp. 16-27
    • Evron, T.1    Moyal-Segal, L.B.2    Lamm, N.3    Geffen, A.4    Soreq, H.5
  • 29
    • 83055198367 scopus 로고    scopus 로고
    • Activation of the alternative NFkappaB pathway improves disease symptoms in a model of Sjogren's syndrome
    • A. Gilboa-Geffen, Y. Wolf, G. Hanin, N. Melamed-Book, M. Pick, E.R. Bennett, and et al. Activation of the alternative NFkappaB pathway improves disease symptoms in a model of Sjogren's syndrome PLoS One 6 2011 e28727
    • (2011) PLoS One , vol.6 , pp. e28727
    • Gilboa-Geffen, A.1    Wolf, Y.2    Hanin, G.3    Melamed-Book, N.4    Pick, M.5    Bennett, E.R.6
  • 31
    • 33644865015 scopus 로고    scopus 로고
    • MicroRNA modulation of megakaryoblast fate involves cholinergic signaling
    • C. Guimaraes-Sternberg, A. Meerson, I. Shaked, and H. Soreq MicroRNA modulation of megakaryoblast fate involves cholinergic signaling Leuk. Res. 30 2006 583 595
    • (2006) Leuk. Res. , vol.30 , pp. 583-595
    • Guimaraes-Sternberg, C.1    Meerson, A.2    Shaked, I.3    Soreq, H.4
  • 32
    • 0037127007 scopus 로고    scopus 로고
    • Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity
    • E. Meshorer, C. Erb, R. Gazit, L. Pavlovsky, D. Kaufer, A. Friedman, and et al. Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity Science 295 2002 508 512
    • (2002) Science , vol.295 , pp. 508-512
    • Meshorer, E.1    Erb, C.2    Gazit, R.3    Pavlovsky, L.4    Kaufer, D.5    Friedman, A.6
  • 34
    • 29644435705 scopus 로고    scopus 로고
    • Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses
    • D. Grisaru, M. Pick, C. Perry, E.H. Sklan, R. Almog, I. Goldberg, and et al. Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses J. Immunol. 176 2006 27 35
    • (2006) J. Immunol. , vol.176 , pp. 27-35
    • Grisaru, D.1    Pick, M.2    Perry, C.3    Sklan, E.H.4    Almog, R.5    Goldberg, I.6
  • 35
    • 84879073845 scopus 로고    scopus 로고
    • MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease
    • N. Maharshak, S. Shenhar-Tsarfaty, N. Aroyo, N. Orpaz, I. Guberman, J. Canaani, and et al. MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease Inflamm. Bowel Dis. 19 2013 1346 1353
    • (2013) Inflamm. Bowel Dis. , vol.19 , pp. 1346-1353
    • Maharshak, N.1    Shenhar-Tsarfaty, S.2    Aroyo, N.3    Orpaz, N.4    Guberman, I.5    Canaani, J.6
  • 36
    • 33845675368 scopus 로고    scopus 로고
    • Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure
    • R.O. Browne, L.B. Moyal-Segal, D. Zumsteg, Y. David, O. Kofman, A. Berger, and et al. Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure FASEB J. 20 2006 1733 1735
    • (2006) FASEB J. , vol.20 , pp. 1733-1735
    • Browne, R.O.1    Moyal-Segal, L.B.2    Zumsteg, D.3    David, Y.4    Kofman, O.5    Berger, A.6
  • 38
    • 33845673318 scopus 로고    scopus 로고
    • Neuromuscular therapeutics by RNA-targeted suppression of ACHE gene expression
    • A. Dori, and H. Soreq Neuromuscular therapeutics by RNA-targeted suppression of ACHE gene expression Ann. N. Y. Acad. Sci. 1082 2006 77 90
    • (2006) Ann. N. Y. Acad. Sci. , vol.1082 , pp. 77-90
    • Dori, A.1    Soreq, H.2


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