Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis

Brain

Volumn 138, Issue 6, 2015, Pages 1531-1547

  Van Luijn, Marvin M ^a   Kreft, Karim L ^a   Jongsma, Marlieke L ^b   Mes, Steven W ^a   Wierenga Wolf, Annet F ^a   Van Meurs, Marjan ^a   Melief, Marie José ^a   Van Der Kant, Rik ^b   Janssen, Lennert ^b   Janssen, Hans ^b   Tan, Rusung ^c,d   Priatel, John J ^d   Neefjes, Jacques ^b   Laman, Jon D ^a   Hintzen, Rogier Q ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c SIDRA MEDICAL AND RESEARCH CENTER   (Qatar)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antigen presentation; Autoimmune disease; C type lectin; Human leukocyte antigen; Immunogenetics

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; HLA ANTIGEN CLASS 2; VITAMIN D; CLEC16A PROTEIN, HUMAN; GLUCOSE TRANSPORTER; LECTIN; RILP PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA;

ADULT; AGED; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; BIOGENESIS; CELL INFILTRATION; CELL MIGRATION; CLEC16A GENE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; ENDOSOME; FEMALE; GENE; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LEUKOCYTE; MAJOR CLINICAL STUDY; MONOCYTE; MULTIPLE SCLEROSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; UPREGULATION; WHITE MATTER; ADOLESCENT; BIOSYNTHESIS; CASE CONTROL STUDY; CELL CULTURE; DRUG EFFECTS; GENE SILENCING; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PHYSIOLOGY; PROTEIN TRANSPORT; ULTRASTRUCTURE; YOUNG ADULT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; AGED; ANTIGEN-PRESENTING CELLS; CASE-CONTROL STUDIES; CELLS, CULTURED; DENDRITIC CELLS; ENDOSOMES; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENETIC PREDISPOSITION TO DISEASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LECTINS, C-TYPE; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MONOSACCHARIDE TRANSPORT PROTEINS; MULTIPLE SCLEROSIS; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; UP-REGULATION; VITAMIN D; WHITE MATTER; YOUNG ADULT;

EID: 84933553560     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awv080     Document Type: Article

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