The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis

Journal of Immunology

Volumn 188, Issue 4, 2012, Pages 1874-1883

  Kreft, Karim L ^a   Verbraak, Evert ^a   Wierenga Wolf, Annet F ^a   Van Meurs, Marjan ^a   Oostra, Ben A ^a   Laman, Jon D ^a   Hintzen, Rogier Q ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANZYME A; GRANZYME B; INTERLEUKIN 7 RECEPTOR ALPHA; MESSENGER RNA; STAT5 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION;

ADOLESCENT; ADULT; AGED; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GRANZYMES; HUMANS; INTERLEUKIN-7; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MULTIPLE SCLEROSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN-7; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR;

EID: 84856871924     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102559     Document Type: Article

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