-
2
-
-
84896690513
-
Prevalence of childhood and adult obesity in the United States 2011-2012
-
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 2014;311(8):806-14
-
(2014)
JAMA
, vol.311
, Issue.8
, pp. 806-814
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
3
-
-
84933578904
-
-
WHO
-
WHO. 2015.www.who.int/mediacentre/factsheets/fs311/en/index.html.
-
(2015)
-
-
-
4
-
-
84884225090
-
Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries
-
Boutayeb A, Boutayeb S, Boutayeb W. Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries. Int J Equity Health 2013;12:60
-
(2013)
Int J Equity Health
, vol.12
, pp. 60
-
-
Boutayeb, A.1
Boutayeb, S.2
Boutayeb, W.3
-
5
-
-
84871784819
-
Association of all-cause mortality with overweight and obesity using standard body mass index categories: A systematic review and meta-analysis
-
Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 2013;309(1):71-82
-
(2013)
JAMA
, vol.309
, Issue.1
, pp. 71-82
-
-
Flegal, K.M.1
Kit, B.K.2
Orpana, H.3
Graubard, B.I.4
-
6
-
-
84890547453
-
The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications
-
Madsbad S. The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications. Diabetes obes Metab 2014;16(1):9-21
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.1
, pp. 9-21
-
-
Madsbad, S.1
-
7
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup A, Rossner S, Van Gaal L, et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009; 374(9701):1606-16
-
(2009)
Lancet
, vol.374
, Issue.9701
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
-
8
-
-
84887840117
-
Weight maintenance and additional weight loss with liraglutide after low-calorie-dietinduced weight loss: The SCALE Maintenance randomized study
-
Wadden TA, Hollander P, Klein S, et al. Weight maintenance and additional weight loss with liraglutide after low-calorie-dietinduced weight loss: the SCALE Maintenance randomized study. Int J Obes (Lond) 2013;37(11):1443-51.
-
(2013)
Int J Obes (Lond)
, vol.37
, Issue.11
, pp. 1443-1451
-
-
Wadden, T.A.1
Hollander, P.2
Klein, S.3
-
9
-
-
79955649140
-
Pharmacology, efficacy and safety of liraglutide in the management of type 2 diabetes
-
Neumiller JJ, Sonnett TE, Wood LD, et al. Pharmacology, efficacy and safety of liraglutide in the management of type 2 diabetes. Diabetes Metab Syndr Obes 2010;3:215-26
-
(2010)
Diabetes Metab Syndr Obes
, vol.3
, pp. 215-226
-
-
Neumiller, J.J.1
Sonnett, T.E.2
Wood, L.D.3
-
10
-
-
84929963055
-
-
FDA [Last accessed 23 December 2014]
-
FDA. FDA approves weight-management drug Saxenda. 2014.www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427913.htm [Last accessed 23 December 2014]
-
(2014)
FDA Approves Weight-management Drug Saxenda
-
-
-
11
-
-
84933578905
-
-
[Last accessed 23 March 2015]
-
Nordisk N. Company Announcement. 2015.www.novonordisk.com/bin/getPDF.1905678.pdf [Last accessed 23 March 2015]
-
(2015)
Company Announcement
-
-
Nordisk, N.1
-
12
-
-
78650660194
-
Diabesity: An overview of a rising epidemic
-
Farag YM, Gaballa MR. Diabesity: an overview of a rising epidemic. Nephrol Dial Transplant 2011;26(1):28-35
-
(2011)
Nephrol Dial Transplant
, vol.26
, Issue.1
, pp. 28-35
-
-
Farag, Y.M.1
Gaballa, M.R.2
-
13
-
-
84910028337
-
Therapies for inter-relating diabetes and obesity-GLP-1 and obesity
-
Iepsen EW, Torekov SS, Holst JJ. Therapies for inter-relating diabetes and obesity-GLP-1 and obesity. Expert Opin Pharmacother 2014;15(17):2487-500
-
(2014)
Expert Opin Pharmacother
, vol.15
, Issue.17
, pp. 2487-2500
-
-
Iepsen, E.W.1
Torekov, S.S.2
Holst, J.J.3
-
14
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev 2007;87(4):1409-39
-
(2007)
Physiol Rev
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
15
-
-
15044354562
-
Glucagon-related peptide 1 (GLP-1): Hormone and neurotransmitter
-
Larsen PJ, Holst JJ. Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter. Regul Pept 2005;128(2): 97-107
-
(2005)
Regul Pept
, vol.128
, Issue.2
, pp. 97-107
-
-
Larsen, P.J.1
Holst, J.J.2
-
16
-
-
16344374278
-
Glucagon-like peptide 1(GLP-1) in biology and pathology
-
Meier JJ, Nauck MA. Glucagon-like peptide 1(GLP-1) in biology and pathology. Diabetes Metab Res Rev 2005;21(2):91-117
-
(2005)
Diabetes Metab Res Rev
, vol.21
, Issue.2
, pp. 91-117
-
-
Meier, J.J.1
Nauck, M.A.2
-
17
-
-
79956296360
-
Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes
-
Torekov SS, Kipnes MS, Harley RE, et al. Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes. Diabetes obes Metab 2011; 13(7):639-43
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.7
, pp. 639-643
-
-
Torekov, S.S.1
Kipnes, M.S.2
Harley, R.E.3
-
18
-
-
84898800517
-
Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus
-
Torekov SS, Holst JJ, Ehlers MR. Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus. Diabetes obes Metab 2014;16(5):451-6
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.5
, pp. 451-456
-
-
Torekov, S.S.1
Holst, J.J.2
Ehlers, M.R.3
-
19
-
-
19344375318
-
Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
-
Chelikani PK, Haver AC, Reidelberger RD. Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats. Am J Physiol 2005;288(6):R1695-706
-
(2005)
Am J Physiol
, vol.288
, Issue.6
, pp. R1695-R1706
-
-
Chelikani, P.K.1
Haver, A.C.2
Reidelberger, R.D.3
-
20
-
-
0029859220
-
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M, Larsen PJ, Goke R, et al.Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996;271(4 Pt 2): R848-56
-
(1996)
Am J Physiol
, vol.271
, Issue.4
, pp. R848-R856
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Goke, R.3
-
21
-
-
0029903111
-
Glucagon-like peptide i receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide i
-
Orskov C, Poulsen SS, Moller M, Holst JJ. Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996;45(6):832-5
-
(1996)
Diabetes
, vol.45
, Issue.6
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
22
-
-
84907495472
-
The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss
-
Secher A, Jelsing J, Baquero AF, et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. J Clin Invest 2014;124(10):4473-88
-
(2014)
J Clin Invest
, vol.124
, Issue.10
, pp. 4473-4488
-
-
Secher, A.1
Jelsing, J.2
Baquero, A.F.3
-
23
-
-
80155165170
-
The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1
-
Hayes MR, Kanoski SE, De Jonghe BC, et al. The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1. Am J Physiol 2011;301(5):R1479-85
-
(2011)
Am J Physiol
, vol.301
, Issue.5
, pp. R1479-R1485
-
-
Hayes, M.R.1
Kanoski, S.E.2
De Jonghe, B.C.3
-
24
-
-
77953724336
-
Role of the glucagon-like-peptide-1 receptor in the control of energy balance
-
Hayes MR, De Jonghe BC, Kanoski SE. Role of the glucagon-like-peptide-1 receptor in the control of energy balance. Physiol Behav 2010;100(5):503-10
-
(2010)
Physiol Behav
, vol.100
, Issue.5
, pp. 503-510
-
-
Hayes, M.R.1
De Jonghe, B.C.2
Kanoski, S.E.3
-
25
-
-
79953758204
-
Glucagon-like peptide 1 and the brain: Central actions-central sources
-
Trapp S, Hisadome K. Glucagon-like peptide 1 and the brain: central actions-central sources Auton Neurosci 2011;161(1-2):14-19
-
(2011)
Auton Neurosci
, vol.161
, Issue.1-2
, pp. 14-19
-
-
Trapp, S.1
Hisadome, K.2
-
26
-
-
0030967436
-
Central administration of glucagon-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat
-
Larsen PJ, Tang-Christensen M, Jessop DS. Central administration of glucagon-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 1997;138(10):4445-55
-
(1997)
Endocrinology
, vol.138
, Issue.10
, pp. 4445-4455
-
-
Larsen, P.J.1
Tang-Christensen, M.2
Jessop, D.S.3
-
27
-
-
0041307370
-
Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons
-
Vrang N, Phifer CB, Corkern MM, Berthoud HR. Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons. American J Physiol 2003;285(2): R470-8
-
(2003)
American J Physiol
, vol.285
, Issue.2
, pp. R470-R478
-
-
Vrang, N.1
Phifer, C.B.2
Corkern, M.M.3
Berthoud, H.R.4
-
28
-
-
80054035293
-
Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake
-
Dossat AM, Lilly N, Kay K, Williams DL. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. J Neurosci 2011;31(41):14453-7
-
(2011)
J Neurosci
, vol.31
, Issue.41
, pp. 14453-14457
-
-
Dossat, A.M.1
Lilly, N.2
Kay, K.3
Williams, D.L.4
-
29
-
-
13644268431
-
The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem
-
Alvarez E, Martinez MD, Roncero I, et al. The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem. J Neurochem 2005;92(4):798-806
-
(2005)
J Neurochem
, vol.92
, Issue.4
, pp. 798-806
-
-
Alvarez, E.1
Martinez, M.D.2
Roncero, I.3
-
30
-
-
0022461548
-
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
-
Nauck MA, Homberger E, Siegel EG, et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 1986;63(2):492-8
-
(1986)
J Clin Endocrinol Metab
, vol.63
, Issue.2
, pp. 492-498
-
-
Nauck, M.A.1
Homberger, E.2
Siegel, E.G.3
-
31
-
-
84860242081
-
Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
-
Knop FK, Aaboe K, Vilsboll T, et al. Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity. Diabetes obes Metab 2012;14(6):500-10
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.6
, pp. 500-510
-
-
Knop, F.K.1
Aaboe, K.2
Vilsboll, T.3
-
32
-
-
48449093468
-
Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
-
Muscelli E, Mari A, Casolaro A, et al. Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. Diabetes 2008;57(5):1340-8
-
(2008)
Diabetes
, vol.57
, Issue.5
, pp. 1340-1348
-
-
Muscelli, E.1
Mari, A.2
Casolaro, A.3
-
33
-
-
84962109423
-
Glucagon-like peptide-1 (GLP-1) response to oral glucose is reduced in pre-diabetes, screen-detected type 2 diabetes and obesity, and influenced by sex: The ADDITION-PRO Study
-
Faerch K, Torekov SS, Vistisen D, et al. Glucagon-like peptide-1 (GLP-1) response to oral glucose is reduced in pre-diabetes, screen-detected type 2 diabetes and obesity, and influenced by sex: The ADDITION-PRO Study. Diabetes 2015
-
(2015)
Diabetes
-
-
Faerch, K.1
Torekov, S.S.2
Vistisen, D.3
-
34
-
-
84862305704
-
Emerging role of GLP-1 receptor agonists in the treatment of obesity
-
Neff LM, Kushner RF, Emerging role of GLP-1 receptor agonists in the treatment of obesity. Diabetes Metab Syndr Obes 2010;3:263-73
-
(2010)
Diabetes Metab Syndr Obes
, vol.3
, pp. 263-273
-
-
Neff, L.M.1
Kushner, R.F.2
-
35
-
-
84865984023
-
Patient-reported outcomes in trials of incretin-based therapies in patients with type 2 diabetes mellitus
-
Davies M, Speight J. Patient-reported outcomes in trials of incretin-based therapies in patients with type 2 diabetes mellitus. Diabetes obes Metab 2012;14(10):882-892
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.10
, pp. 882-892
-
-
Davies, M.1
Speight, J.2
-
36
-
-
34548034895
-
Effect of renal impairment on the pharmacokinetics of exenatide
-
Linnebjerg H, Kothare PA, Park S, et al. Effect of renal impairment on the pharmacokinetics of exenatide. Br J Clin Pharmacol 2007;64(3):317-27
-
(2007)
Br J Clin Pharmacol
, vol.64
, Issue.3
, pp. 317-327
-
-
Linnebjerg, H.1
Kothare, P.A.2
Park, S.3
-
37
-
-
77955887980
-
Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: A randomized double-blind placebo-controlled trial
-
Ratner RE, Rosenstock J, Boka G. Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial. Diabetic Med 2010;27(9):1024-32
-
(2010)
Diabetic Med
, vol.27
, Issue.9
, pp. 1024-1032
-
-
Ratner, R.E.1
Rosenstock, J.2
Boka, G.3
-
38
-
-
84870054636
-
GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nature reviews
-
Meier JJ. GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nature reviews. Endocrinology 2012;8(12):728-42
-
(2012)
Endocrinology
, vol.8
, Issue.12
, pp. 728-742
-
-
Meier, J.J.1
-
39
-
-
81155154236
-
Liraglutide: A review of its use in the management of type 2 diabetes mellitus
-
Perry CM. Liraglutide: a review of its use in the management of type 2 diabetes mellitus. Drugs 2011;71(17):2347-73
-
(2011)
Drugs
, vol.71
, Issue.17
, pp. 2347-2373
-
-
Perry, C.M.1
-
40
-
-
70349095558
-
Liraglutide: A review of its use in type 2 diabetes mellitus
-
Croom KF, McCormack PL. Liraglutide: a review of its use in type 2 diabetes mellitus. Drugs 2009;69(14):1985-2004
-
(2009)
Drugs
, vol.69
, Issue.14
, pp. 1985-2004
-
-
Croom, K.F.1
McCormack, P.L.2
-
41
-
-
79960741385
-
Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists liraglutide and exendin-4
-
Kanoski SE, Fortin SM, Arnold M, et al. Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4. Endocrinology 2011;152(8):3103-12
-
(2011)
Endocrinology
, vol.152
, Issue.8
, pp. 3103-3112
-
-
Kanoski, S.E.1
Fortin, S.M.2
Arnold, M.3
-
42
-
-
84902208322
-
Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect
-
Sisley S, Gutierrez-Aguilar R, Scott M, et al. Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. J Clin Invest 2014;124(6):2456-63
-
(2014)
J Clin Invest
, vol.124
, Issue.6
, pp. 2456-2463
-
-
Sisley, S.1
Gutierrez-Aguilar, R.2
Scott, M.3
-
43
-
-
79960839795
-
The contribution of serotonin 5-HT2C and melanocortin-4 receptors to the satiety signaling of glucagon-like peptide 1 and liraglutide a glucagon-like peptide 1 receptor agonist in mice
-
Nonogaki K, Suzuki M, Sanuki M, et al. The contribution of serotonin 5-HT2C and melanocortin-4 receptors to the satiety signaling of glucagon-like peptide 1 and liraglutide, a glucagon-like peptide 1 receptor agonist, in mice. Biochem Biophys Res Commun 2011;411(2):445-8
-
(2011)
Biochem Biophys Res Commun
, vol.411
, Issue.2
, pp. 445-448
-
-
Nonogaki, K.1
Suzuki, M.2
Sanuki, M.3
-
44
-
-
77649187436
-
Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: A link between diabetes and Alzheimer's disease
-
McClean PL, Gault VA, Harriott P, Holscher C. Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease. Eur J Pharmacol 2010;630(1-3):158-62
-
(2010)
Eur J Pharmacol
, vol.630
, Issue.1-3
, pp. 158-162
-
-
McClean, P.L.1
Gault, V.A.2
Harriott, P.3
Holscher, C.4
-
45
-
-
84904468017
-
Glucagon-like Peptide-1 receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake and motivation to feed
-
Alhadeff AL, Baird JP, Swick JC, et al. Glucagon-like Peptide-1 receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake and motivation to feed. Neuropsychopharmacology 2014;39(9): 2233-43
-
(2014)
Neuropsychopharmacology
, vol.39
, Issue.9
, pp. 2233-2243
-
-
Alhadeff, A.L.1
Baird, J.P.2
Swick, J.C.3
-
46
-
-
84907495079
-
GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK
-
Beiroa D, Imbernon M, Gallego R, et al. GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. Diabetes 2014; 63(10):3346-58
-
(2014)
Diabetes
, vol.63
, Issue.10
, pp. 3346-3358
-
-
Beiroa, D.1
Imbernon, M.2
Gallego, R.3
-
47
-
-
84928926835
-
Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
-
Iepsen EW, Lundgren J, Dirksen C, et al. Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. Int J Obes (Lond) 2014
-
(2014)
Int J Obes (Lond)
-
-
Iepsen, E.W.1
Lundgren, J.2
Dirksen, C.3
-
48
-
-
84901593760
-
Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: Differences and similarities
-
Lund A, Knop FK, Vilsboll T. Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities. Eur J Intern Med 2014;25(5):407-14
-
(2014)
Eur J Intern Med
, vol.25
, Issue.5
, pp. 407-414
-
-
Lund, A.1
Knop, F.K.2
Vilsboll, T.3
-
49
-
-
84976585919
-
-
A/. NN Available from [Last accessed 19 December 2014]
-
A/. NN. Victoza: EU summary of product characteristics. 2014. Available from: www. ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/001026/WC500050017.pdf [Last accessed 19 December 2014]
-
(2014)
Victoza: EU Summary of Product Characteristics
-
-
-
50
-
-
84933578907
-
-
Information NNASVlroi-Up Available from [Last accessed 19 December 2014]
-
Information NNASVlroi-Up. 2013. Available from: www.novo-pi.com/victoza. pdf [Last accessed 19 December 2014]
-
(2013)
-
-
-
51
-
-
69949163754
-
Exenatide and liraglutide: Different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results
-
Madsbad S. Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results. Best Pract Res Clin Endocrinol Metabol 2009;23(4):463-77
-
(2009)
Best Pract Res Clin Endocrinol Metabol
, vol.23
, Issue.4
, pp. 463-477
-
-
Madsbad, S.1
-
53
-
-
79953040963
-
An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future
-
Madsbad S, Kielgast U, Asmar M, et al. An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future. Diabetes obes Metab 2011;13(5): 394-407
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.5
, pp. 394-407
-
-
Madsbad, S.1
Kielgast, U.2
Asmar, M.3
-
54
-
-
74549177233
-
A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus
-
Montanya E, Sesti G. A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus. Clin Therap 2009;31(11):2472-88
-
(2009)
Clin Therap
, vol.31
, Issue.11
, pp. 2472-2488
-
-
Montanya, E.1
Sesti, G.2
-
55
-
-
33745276226
-
An open-label, parallel group study investigating the effects of age and gender on the pharmacokinetics of the once-daily glucagon-like peptide-1 analogue liraglutide
-
Damholt B, Golor G, Wierich W, et al. An open-label, parallel group study investigating the effects of age and gender on the pharmacokinetics of the once-daily glucagon-like peptide-1 analogue liraglutide. J Clin Pharmacol 2006;46(6):635-41
-
(2006)
J Clin Pharmacol
, vol.46
, Issue.6
, pp. 635-641
-
-
Damholt, B.1
Golor, G.2
Wierich, W.3
-
56
-
-
0035081369
-
No reactive hypoglycaemia in Type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose
-
Vilsboll T, Krarup T, Madsbad S, Holst JJ. No reactive hypoglycaemia in Type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose. Diabetic Med 2001;18(2):144-9
-
(2001)
Diabetic Med
, vol.18
, Issue.2
, pp. 144-149
-
-
Vilsboll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
57
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
-
Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009; 374(9683):39-47
-
(2009)
Lancet
, vol.374
, Issue.9683
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
-
58
-
-
84907291964
-
Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease
-
Idorn T, Knop FK, Jorgensen MB, et al. Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease. J Clin Endocrinol Metab 2014; 99(7):2457-66
-
(2014)
J Clin Endocrinol Metab
, vol.99
, Issue.7
, pp. 2457-2466
-
-
Idorn, T.1
Knop, F.K.2
Jorgensen, M.B.3
-
59
-
-
84907519425
-
Liraglutide's safety tolerability pharmacokinetics and pharmacodynamics in pediatric type 2 diabetes: A randomized double-blind placebo-controlled trial
-
Klein DJ, Battelino T, Chatterjee DJ, et al. Liraglutide's safety, tolerability, pharmacokinetics, and pharmacodynamics in pediatric type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Technol Therap 2014;16(10): 679-87
-
(2014)
Diabetes Technol Therap
, vol.16
, Issue.10
, pp. 679-687
-
-
Klein, D.J.1
Battelino, T.2
Chatterjee, D.J.3
-
60
-
-
84885309586
-
Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus
-
Consoli A, Formoso G. Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus Diabetes obes Metab 2013;15(11):967-77
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.11
, pp. 967-977
-
-
Consoli, A.1
Formoso, G.2
-
61
-
-
62449129181
-
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)
-
Marre M, Shaw J, Brandle M, et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU). Diabetic Med 2009;26(3): 268-78
-
(2009)
Diabetic Med
, vol.26
, Issue.3
, pp. 268-278
-
-
Marre, M.1
Shaw, J.2
Brandle, M.3
-
62
-
-
70450190143
-
Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue
-
Jendle J, Nauck MA, Matthews DR, et al. Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes obes Metab 2009;11(12):1163-72
-
(2009)
Diabetes Obes Metab
, vol.11
, Issue.12
, pp. 1163-1172
-
-
Jendle, J.1
Nauck, M.A.2
Matthews, D.R.3
-
63
-
-
84873085581
-
Long-term efficacy and safety comparison of liraglutide glimepiride and placebo all in combination with metformin in type 2 diabetes: 2-year results from the LEAD-2 study
-
Nauck M, Frid A, Hermansen K, et al. Long-term efficacy and safety comparison of liraglutide, glimepiride and placebo, all in combination with metformin in type 2 diabetes: 2-year results from the LEAD-2 study. Diabetes obes Metab 2013; 15(3):204-12
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.3
, pp. 204-212
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
64
-
-
59449101432
-
Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel-treatment trial
-
Garber A, Henry R, Ratner R, et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial. Lancet 2009;373(9662):473-81
-
(2009)
Lancet
, vol.373
, Issue.9662
, pp. 473-481
-
-
Garber, A.1
Henry, R.2
Ratner, R.3
-
65
-
-
79951906623
-
Liraglutide a once-daily human glucagon-like peptide 1 analogue provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes
-
Garber A, Henry RR, Ratner R, et al. Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes. Diabetes obes Metab 2011;13(4):348-56
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.4
, pp. 348-356
-
-
Garber, A.1
Henry, R.R.2
Ratner, R.3
-
66
-
-
67650066860
-
Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met +TZD)
-
Zinman B, Gerich J, Buse JB, et al. Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met +TZD). Diabetes Care 2009;32(7):1224-30
-
(2009)
Diabetes Care
, vol.32
, Issue.7
, pp. 1224-1230
-
-
Zinman, B.1
Gerich, J.2
Buse, J.B.3
-
67
-
-
77952309372
-
Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: A 26-week randomised parallel-group open-label trial
-
Pratley RE, Nauck M, Bailey T, et al. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 2010;375(9724): 1447-56
-
(2010)
Lancet
, vol.375
, Issue.9724
, pp. 1447-1456
-
-
Pratley, R.E.1
Nauck, M.2
Bailey, T.3
-
68
-
-
79952755181
-
One year of liraglutide treatment offers sustained and more effective glycaemic control and weight reduction compared with sitagliptin, both in combination with metformin, in patients with type 2 diabetes: A randomised, parallel-group, open-label trial
-
Pratley R, Nauck M, Bailey T, et al. One year of liraglutide treatment offers sustained and more effective glycaemic control and weight reduction compared with sitagliptin, both in combination with metformin, in patients with type 2 diabetes: a randomised, parallel-group, open-label trial. Int J Clin Pract 2011;65(4):397-407
-
(2011)
Int J Clin Pract
, vol.65
, Issue.4
, pp. 397-407
-
-
Pratley, R.1
Nauck, M.2
Bailey, T.3
-
69
-
-
69949117621
-
Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): A randomised controlled trial
-
Russell-Jones D, Vaag A, Schmitz O, et al. Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial. Diabetologia 2009;52(10): 2046-55
-
(2009)
Diabetologia
, vol.52
, Issue.10
, pp. 2046-2055
-
-
Russell-Jones, D.1
Vaag, A.2
Schmitz, O.3
-
70
-
-
84933578908
-
Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes
-
D'Alessio D, Haring HU, Charbonnel B, et al. Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes. Diabetes Obes Metab 2014
-
(2014)
Diabetes Obes Metab
-
-
D'Alessio, D.1
Haring, H.U.2
Charbonnel, B.3
-
71
-
-
84910049684
-
Contribution of liraglutide in the fixed-ratio combination of insulin degludec and liraglutide (IDegLira)
-
Buse JB, Vilsboll T, Thurman J, et al. Contribution of liraglutide in the fixed-ratio combination of insulin degludec and liraglutide (IDegLira). Diabetes Care 2014; 37(11):2926-33
-
(2014)
Diabetes Care
, vol.37
, Issue.11
, pp. 2926-2933
-
-
Buse, J.B.1
Vilsboll, T.2
Thurman, J.3
-
72
-
-
84872084453
-
Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): A randomised open-label study
-
Buse JB, Nauck M, Forst T, et al. Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomised, open-label study. Lancet 2013;381(9861):117-24
-
(2013)
Lancet
, vol.381
, Issue.9861
, pp. 117-124
-
-
Buse, J.B.1
Nauck, M.2
Forst, T.3
-
73
-
-
84878863716
-
Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin
-
Kapitza C, Forst T, Coester HV, et al. Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin. Diabetes obes Metab 2013;15(7):642-9
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.7
, pp. 642-649
-
-
Kapitza, C.1
Forst, T.2
Coester, H.V.3
-
74
-
-
84908177336
-
Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): A randomised open-label phase 3 non-inferiority trial
-
Dungan KM, Povedano ST, Forst T, et al. Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial. Lancet 2014; 384(9951):1349-57
-
(2014)
Lancet
, vol.384
, Issue.9951
, pp. 1349-1357
-
-
Dungan, K.M.1
Povedano, S.T.2
Forst, T.3
-
75
-
-
84899585635
-
Once-weekly albiglutide versus once-daily liraglutide in patients with type 2 diabetes inadequately controlled on oral drugs (HARMONY 7): A randomised open-label multicentre non-inferiority phase 3 study
-
Pratley RE, Nauck MA, Barnett AH, et al. Once-weekly albiglutide versus once-daily liraglutide in patients with type 2 diabetes inadequately controlled on oral drugs (HARMONY 7): a randomised, open-label, multicentre, non-inferiority phase 3 study. Lancet 2014;2(4):289-97
-
(2014)
Lancet
, vol.2
, Issue.4
, pp. 289-297
-
-
Pratley, R.E.1
Nauck, M.A.2
Barnett, A.H.3
-
76
-
-
84862207266
-
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
-
Astrup A, Carraro R, Finer N, et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond) 2012;36(6):843-54
-
(2012)
Int J Obes (Lond)
, vol.36
, Issue.6
, pp. 843-854
-
-
Astrup, A.1
Carraro, R.2
Finer, N.3
-
77
-
-
84933578909
-
-
Press Release Available from
-
Nordisk N. Press Release. 2014. Available from: www.novonordisk.com/bin/getPDF.1868303.pdf
-
(2014)
-
-
Nordisk, N.1
-
78
-
-
84933578910
-
-
ADA oral abstracts-97-OR Available from
-
ADA oral abstracts-97-OR. 2014. Available from: http://diabetes. diabetesjournals.org/content/63/Supplement-1/A1.full.pdf+html
-
(2014)
-
-
-
79
-
-
0030944526
-
Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats
-
Thiele TE, Van Dijk G, Campfield LA, et al. Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats. Am J Physiol 1997;272(2 Pt 2): R726-30
-
(1997)
Am J Physiol
, vol.272
, Issue.2
, pp. R726-R730
-
-
Thiele, T.E.1
Van Dijk, G.2
Campfield, L.A.3
-
80
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
-
Buse JB, Henry RR, Han J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004;27(11):2628-35
-
(2004)
Diabetes Care
, vol.27
, Issue.11
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
-
81
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: The LEAD (liraglutide effect and action in diabetes)-2 study
-
Nauck M, Frid A, Hermansen K, et al. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study. Diabetes Care 2009;32(1):84-90
-
(2009)
Diabetes Care
, vol.32
, Issue.1
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
82
-
-
73349102524
-
The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: An overview of the LEAD 1-5 studies
-
Blonde L, Russell-Jones D. The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: an overview of the LEAD 1-5 studies. Diabetes obes Metab 2009;11(Suppl 3): 26-34
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 26-34
-
-
Blonde, L.1
Russell-Jones, D.2
-
83
-
-
84899906592
-
Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults
-
Lean ME, Carraro R, Finer N, et al. Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults. Int J Obes (Lond) 2014;38(5):689-97
-
(2014)
Int J Obes (Lond)
, vol.38
, Issue.5
, pp. 689-697
-
-
Lean, M.E.1
Carraro, R.2
Finer, N.3
-
84
-
-
77950221874
-
Glucagon and glucagon-like peptides 1 and 2
-
Holst JJ. Glucagon and glucagon-like peptides 1 and 2. Results Probl Cell Differ 2010;50:121-35
-
(2010)
Results Probl Cell Differ
, vol.50
, pp. 121-135
-
-
Holst, J.J.1
-
85
-
-
84859103180
-
The effect of glucagon-like peptide 1 on cardiovascular risk. Nature reviews
-
Sivertsen J, Rosenmeier J, Holst JJ, Vilsboll T. The effect of glucagon-like peptide 1 on cardiovascular risk. Nature reviews. Cardiology 2012;9(4):209-22
-
(2012)
Cardiology
, vol.9
, Issue.4
, pp. 209-222
-
-
Sivertsen, J.1
Rosenmeier, J.2
Holst, J.J.3
Vilsboll, T.4
-
86
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways
-
Ban K, Noyan-Ashraf MH, Hoefer J, et al. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways. Circulation2008; 117(18):2340-50
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
-
87
-
-
0027495779
-
GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery
-
Richter G, Feddersen O, Wagner U, et al. GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery. Am J Physiol 1993; 265(4 Pt 1):L374-81
-
(1993)
Am J Physiol
, vol.265
, Issue.4
, pp. L374-L381
-
-
Richter, G.1
Feddersen, O.2
Wagner, U.3
-
88
-
-
84897852105
-
GLP-1 receptor localization in monkey and human tissue: Novel distribution revealed with extensively validated monoclonal antibody
-
Pyke C, Heller RS, Kirk RK, et al. GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody. Endocrinology 2014;155(4): 1280-90
-
(2014)
Endocrinology
, vol.155
, Issue.4
, pp. 1280-1290
-
-
Pyke, C.1
Heller, R.S.2
Kirk, R.K.3
-
89
-
-
84933578911
-
Twelve-month treatment with Liraglutide ameliorates Visceral Adiposity Index and common cardiovascular risk factors in type 2 diabetes outpatients
-
Russo GT, Labate AM, Giandalia A, et al. Twelve-month treatment with Liraglutide ameliorates Visceral Adiposity Index and common cardiovascular risk factors in type 2 diabetes outpatients. J Endocrinol Investig 2014
-
(2014)
J Endocrinol Investig
-
-
Russo, G.T.1
Labate, A.M.2
Giandalia, A.3
-
90
-
-
80052039077
-
Cardiovascular safety of liraglutide assessed in a patient-level pooled analysis of phase 2: 3 liraglutide clinical development studies
-
Marso SP, Lindsey JB, Stolker JM, et al. Cardiovascular safety of liraglutide assessed in a patient-level pooled analysis of phase 2: 3 liraglutide clinical development studies. Diabetes Vasc Dis Res 2011;8(3):237-40
-
(2011)
Diabetes Vasc Dis Res
, vol.8
, Issue.3
, pp. 237-240
-
-
Marso, S.P.1
Lindsey, J.B.2
Stolker, J.M.3
-
91
-
-
84886946727
-
Design of the liraglutide effect and action in diabetes: Evaluation of cardiovascular outcome results (LEADER) trial
-
e825
-
Marso SP, Poulter NR, Nissen SE, et al. Design of the liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results (LEADER) trial. Am Heart J 2013;166(5):823-30; e825
-
(2013)
Am Heart J
, vol.166
, Issue.5
, pp. 823-830
-
-
Marso, S.P.1
Poulter, N.R.2
Nissen, S.E.3
-
92
-
-
79958745412
-
Type 2 diabetes mellitus and renal impairment in a large outpatient electronic medical records database: Rates of diagnosis and antihyperglycemic medication dose adjustment
-
Meyers JL, Candrilli SD, Kovacs B. Type 2 diabetes mellitus and renal impairment in a large outpatient electronic medical records database: rates of diagnosis and antihyperglycemic medication dose adjustment. Postgrad Med 2011;123(3): 133-43
-
(2011)
Postgrad Med
, vol.123
, Issue.3
, pp. 133-143
-
-
Meyers, J.L.1
Candrilli, S.D.2
Kovacs, B.3
-
93
-
-
84933578912
-
-
Available from
-
Available from: www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/000698/WC500051845.pdf
-
-
-
-
94
-
-
84933578913
-
-
Available from
-
Available from: www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/001026/WC500050017.pdf
-
-
-
-
95
-
-
79959692519
-
Mild renal impairment and the efficacy and safety of liraglutide
-
Davidson JA, Brett J, Falahati A, Scott D. Mild renal impairment and the efficacy and safety of liraglutide. Endocr Pract 2011; 17(3):345-55
-
(2011)
Endocr Pract
, vol.17
, Issue.3
, pp. 345-355
-
-
Davidson, J.A.1
Brett, J.2
Falahati, A.3
Scott, D.4
-
96
-
-
84877727819
-
Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: Protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study
-
Idorn T, Knop FK, Jorgensen M, et al. Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study. BMJ open 2013;3:4
-
(2013)
BMJ Open
, vol.3
, pp. 4
-
-
Idorn, T.1
Knop, F.K.2
Jorgensen, M.3
-
97
-
-
84933578914
-
-
www.accessdata.fda.gov/drugsatfda-docs/label/2011/022341s004lbl.pdf98.
-
-
-
-
98
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
-
Elashoff M, Matveyenko AV, Gier B, et al. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 2011.141(1): 150-6
-
(2011)
Gastroenterology
, vol.141
, Issue.1
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
-
99
-
-
84933578915
-
Is there a link between liraglutide and pancreatitis a post hoc review of pooled and patient-level data from completed liraglutide type 2 diabetes clinical trials
-
Jensen TM, Saha K, Steinberg WM. Is there a link between liraglutide and pancreatitis a post hoc review of pooled and patient-level data from completed liraglutide type 2 diabetes clinical trials. Diabetes Care 2014
-
(2014)
Diabetes Care
-
-
Jensen, T.M.1
Saha, K.2
Steinberg, W.M.3
-
100
-
-
84893813443
-
A prospective claims-based assessment of the risk of pancreatitis and pancreatic cancer with liraglutide compared to other antidiabetic drugs
-
Funch D, Gydesen H, Tornoe K, et al. A prospective, claims-based assessment of the risk of pancreatitis and pancreatic cancer with liraglutide compared to other antidiabetic drugs. Diabetes obes Metab 2014;16(3):273-5
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.3
, pp. 273-275
-
-
Funch, D.1
Gydesen, H.2
Tornoe, K.3
-
101
-
-
84895787341
-
Glucagon-like peptide-1 receptor agonists and pancreatitis: A meta-analysis of randomized clinical trials
-
Monami M, Dicembrini I, Nardini C, et al. Glucagon-like peptide-1 receptor agonists and pancreatitis: a meta-analysis of randomized clinical trials. Diabetes Res Clin Pract 2014;103(2):269-75
-
(2014)
Diabetes Res Clin Pract
, vol.103
, Issue.2
, pp. 269-275
-
-
Monami, M.1
Dicembrini, I.2
Nardini, C.3
-
102
-
-
84942303261
-
Incretin-based therapies and acute pancreatitis risk: A systematic review and meta-analysis of observational studies
-
Giorda CB, Sacerdote C, Nada E, et al. Incretin-based therapies and acute pancreatitis risk: a systematic review and meta-analysis of observational studies. Endocrine 2015;48(2):461-71
-
(2015)
Endocrine
, vol.48
, Issue.2
, pp. 461-471
-
-
Giorda, C.B.1
Sacerdote, C.2
Nada, E.3
-
103
-
-
84872065294
-
Type 2 diabetes mellitus and the risk of acute pancreatitis: A meta-analysis
-
Yang L, He Z, Tang X, Liu J. Type 2 diabetes mellitus and the risk of acute pancreatitis: a meta-analysis. Eur J Gastroenterol Hepatol 2013;25(2):225-31
-
(2013)
Eur J Gastroenterol Hepatol
, vol.25
, Issue.2
, pp. 225-231
-
-
Yang, L.1
He, Z.2
Tang, X.3
Liu, J.4
-
104
-
-
84873263749
-
Impact of diabetes duration and chronic pancreatitis on the association between type 2 diabetes and pancreatic cancer risk
-
Brodovicz KG, Kou TD, Alexander CM, et al. Impact of diabetes duration and chronic pancreatitis on the association between type 2 diabetes and pancreatic cancer risk. Diabetes obes Metab 2012; 14(12):1123-8
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.12
, pp. 1123-1128
-
-
Brodovicz, K.G.1
Kou, T.D.2
Alexander, C.M.3
-
105
-
-
80052559371
-
The safety and tolerability of GLP-1 receptor agonists in the treatment of type 2 diabetes: A review
-
Aroda VR, Ratner R. The safety and tolerability of GLP-1 receptor agonists in the treatment of type 2 diabetes: a review. Diabetes Metab Res Rev 2011;27(6):528-42
-
(2011)
Diabetes Metab Res Rev
, vol.27
, Issue.6
, pp. 528-542
-
-
Aroda, V.R.1
Ratner, R.2
-
106
-
-
84916630493
-
LEADER 3-lipase and amylase activity in subjects with type 2 diabetes: Baseline data from over 9000 subjects in the LEADER Trial
-
Steinberg WM, Nauck MA, Zinman B, et al. LEADER 3-lipase and amylase activity in subjects with type 2 diabetes: baseline data from over 9000 subjects in the LEADER Trial. Pancreas 2014;43(8): 1223-31
-
(2014)
Pancreas
, vol.43
, Issue.8
, pp. 1223-1231
-
-
Steinberg, W.M.1
Nauck, M.A.2
Zinman, B.3
-
107
-
-
84896731936
-
Pancreatic safety of incretin-based drugs-FDA and EMA assessment
-
Egan AG, Blind E, Dunder K, et al. Pancreatic safety of incretin-based drugs-FDA and EMA assessment. N Engl J Med 2014;370(9):794-7
-
(2014)
N Engl J Med
, vol.370
, Issue.9
, pp. 794-797
-
-
Egan, A.G.1
Blind, E.2
Dunder, K.3
-
108
-
-
84869217643
-
Pancreatitis: A potential complication of liraglutide
-
Franks AS, Lee PH, George CM. Pancreatitis: a potential complication of liraglutide Ann Pharmacother 2012;46(11): 1547-53
-
(2012)
Ann Pharmacother
, vol.46
, Issue.11
, pp. 1547-1553
-
-
Franks, A.S.1
Lee, P.H.2
George, C.M.3
-
109
-
-
77950228684
-
Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
-
Bjerre Knudsen L, Madsen LW, Andersen S, et al. Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. Endocrinology 2010;151(4): 1473-86
-
(2010)
Endocrinology
, vol.151
, Issue.4
, pp. 1473-1486
-
-
Bjerre Knudsen, L.1
Madsen, L.W.2
Andersen, S.3
-
110
-
-
79952284556
-
GLP-1 and calcitonin concentration in humans: Lack of evidence of calcitonin release from sequential screening in over 5000 subjects with type 2 diabetes or nondiabetic obese subjects treated with the human GLP-1 analog, liraglutide
-
Hegedus L, Moses AC, Zdravkovic M, et al. GLP-1 and calcitonin concentration in humans: lack of evidence of calcitonin release from sequential screening in over 5000 subjects with type 2 diabetes or nondiabetic obese subjects treated with the human GLP-1 analog, liraglutide. J Clin Endocrinol Metabol 2011;96(3):853-60
-
(2011)
J Clin Endocrinol Metabol
, vol.96
, Issue.3
, pp. 853-860
-
-
Hegedus, L.1
Moses, A.C.2
Zdravkovic, M.3
-
111
-
-
79956328908
-
Liraglutide treatment is associated with a low frequency and magnitude of antibody formation with no apparent impact on glycemic response or increased frequency of adverse events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials
-
Buse JB, Garber A, Rosenstock J, et al. Liraglutide treatment is associated with a low frequency and magnitude of antibody formation with no apparent impact on glycemic response or increased frequency of adverse events: results from the Liraglutide Effect and Action in Diabetes (LEAD) trials. J Clin Endocrinol Metabol 2011; 96(6):1695-702
-
(2011)
J Clin Endocrinol Metabol
, vol.96
, Issue.6
, pp. 1695-1702
-
-
Buse, J.B.1
Garber, A.2
Rosenstock, J.3
-
112
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
-
DeFronzo RA, Ratner RE, Han J, et al. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005;28(5): 1092-100
-
(2005)
Diabetes Care
, vol.28
, Issue.5
, pp. 1092-1100
-
-
Defronzo, R.A.1
Ratner, R.E.2
Han, J.3
-
113
-
-
84922005537
-
Efficacy of liraglutide in a real-life cohort
-
Heymann A, Maor Y, Goldstein I, et al. Efficacy of liraglutide in a real-life cohort. Diabetes Ther 2014;5(1):193-206
-
(2014)
Diabetes Ther
, vol.5
, Issue.1
, pp. 193-206
-
-
Heymann, A.1
Maor, Y.2
Goldstein, I.3
-
114
-
-
84905730862
-
Improved real-world glycaemic outcomes with liraglutide versus other incretin-based therapies in type 2 diabetes
-
Lee WC, Dekoven M, Bouchard J, et al. Improved real-world glycaemic outcomes with liraglutide versus other incretin-based therapies in type 2 diabetes. Diabetes obes Metab 2014;16(9):819-26
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.9
, pp. 819-826
-
-
Lee, W.C.1
Dekoven, M.2
Bouchard, J.3
-
115
-
-
79955661908
-
DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
-
Blevins T, Pullman J, Malloy J, et al. DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes. J Clin Endocrinol Metab 2011;96(5): 1301-10
-
(2011)
J Clin Endocrinol Metab
, vol.96
, Issue.5
, pp. 1301-1310
-
-
Blevins, T.1
Pullman, J.2
Malloy, J.3
-
116
-
-
70349664297
-
Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes: A randomized controlled trial exploring weekly, biweekly, and monthly dosing
-
Rosenstock J, Reusch J, Bush M, et al. Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes: a randomized controlled trial exploring weekly, biweekly, and monthly dosing. Diabetes Care 2009;32(10):1880-6
-
(2009)
Diabetes Care
, vol.32
, Issue.10
, pp. 1880-1886
-
-
Rosenstock, J.1
Reusch, J.2
Bush, M.3
-
117
-
-
84933578916
-
Succesfull weight loss maintenance includes long-lasting increases in GLP-1 and PYY
-
Abstract [Epub ahead of print]
-
Iepsen EW, Lundgren J, Pedersen O, et al. Succesfull weight loss maintenance includes long-lasting increases in GLP-1 and PYY. Diabetes, ADA Abstract. 2015[Epub ahead of print]
-
(2015)
Diabetes ADA
-
-
Iepsen, E.W.1
Lundgren, J.2
Pedersen, O.3
-
118
-
-
84933578917
-
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
-
[Epub ahead of print]
-
Iepsen EW, Lundgren J, Hartmann B, et al. GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. J Clin Endocrinol Metab. 2015. [Epub ahead of print]
-
(2015)
J Clin Endocrinol Metab.
-
-
Iepsen, E.W.1
Lundgren, J.2
Hartmann, B.3
|