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Volumn 100, Issue 5, 2010, Pages 503-510

Role of the glucagon-like-peptide-1 receptor in the control of energy balance

Author keywords

[No Author keywords available]

Indexed keywords

6 [[2 [[2 (2 CYANO 1 PYRROLIDINYL) 2 OXOETHYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ANTIOBESITY AGENT; EXENDIN 4; EXENDIN 9; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; INCRETIN; LEPTIN; LIRAGLUTIDE; PEPTIDE YY [3-36]; UNCLASSIFIED DRUG;

EID: 77953724336     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2010.02.029     Document Type: Article
Times cited : (142)

References (127)
  • 1
    • 0034967893 scopus 로고    scopus 로고
    • The entero-insular axis in type 2 diabetes-incretins as therapeutic agents
    • Creutzfeldt W. The entero-insular axis in type 2 diabetes-incretins as therapeutic agents. Exp Clin Endocrinol Diabetes 2001, 109(Suppl 2):S288-S303.
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , Issue.SUPPL. 2
    • Creutzfeldt, W.1
  • 2
    • 0025343831 scopus 로고
    • Both amidated and nonamidated forms of glucagon-like peptide I are synthesized in the rat intestine and the pancreas
    • Mojsov S., Kopczynski M.G., Habener J.F. Both amidated and nonamidated forms of glucagon-like peptide I are synthesized in the rat intestine and the pancreas. J Biol Chem 1990, 265:8001-8008.
    • (1990) J Biol Chem , vol.265 , pp. 8001-8008
    • Mojsov, S.1    Kopczynski, M.G.2    Habener, J.F.3
  • 3
    • 70349560878 scopus 로고    scopus 로고
    • Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones
    • Kokrashvili Z., Mosinger B., Margolskee R.F. Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones. Am J Clin Nutr 2009, 90:822S-825S.
    • (2009) Am J Clin Nutr , vol.90
    • Kokrashvili, Z.1    Mosinger, B.2    Margolskee, R.F.3
  • 4
    • 0031029936 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
    • Larsen P.J., Tang-Christensen M., Holst J.J., Orskov C. Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem. Neuroscience 1997, 77:257-270.
    • (1997) Neuroscience , vol.77 , pp. 257-270
    • Larsen, P.J.1    Tang-Christensen, M.2    Holst, J.J.3    Orskov, C.4
  • 5
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • Goke R., Larsen P.J., Mikkelsen J.D., Sheikh S.P. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995, 7:2294-2300.
    • (1995) Eur J Neurosci , vol.7 , pp. 2294-2300
    • Goke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 6
    • 0033545166 scopus 로고    scopus 로고
    • Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
    • Merchenthaler I., Lane M., Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol 1999, 403:261-280.
    • (1999) J Comp Neurol , vol.403 , pp. 261-280
    • Merchenthaler, I.1    Lane, M.2    Shughrue, P.3
  • 7
    • 47949104953 scopus 로고    scopus 로고
    • Caudal brainstem processing is sufficient for behavioral, sympathetic and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
    • Hayes M.R., Skibicka K.P., Grill H.J. Caudal brainstem processing is sufficient for behavioral, sympathetic and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation. Endocrinology 2008.
    • (2008) Endocrinology
    • Hayes, M.R.1    Skibicka, K.P.2    Grill, H.J.3
  • 8
    • 0036896243 scopus 로고    scopus 로고
    • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
    • Kinzig K.P., D'Alessio D.A., Seeley R.J. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002, 22:10470-10476.
    • (2002) J Neurosci , vol.22 , pp. 10470-10476
    • Kinzig, K.P.1    D'Alessio, D.A.2    Seeley, R.J.3
  • 9
    • 0038520993 scopus 로고    scopus 로고
    • Peptides that regulate food intake: glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats
    • Schick R.R., Zimmermann J.P., vorm Walde T., Schusdziarra V. Peptides that regulate food intake: glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats. Am J Physiol Regul Integr Comp Physiol 2003, 284:R1427-R1435.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Schick, R.R.1    Zimmermann, J.P.2    vorm Walde, T.3    Schusdziarra, V.4
  • 10
    • 18144381593 scopus 로고    scopus 로고
    • The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway
    • Abbott C.R., Monteiro M., Small C.J., Sajedi A., Smith K.L., Parkinson J.R., et al. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res 2005, 1044:127-131.
    • (2005) Brain Res , vol.1044 , pp. 127-131
    • Abbott, C.R.1    Monteiro, M.2    Small, C.J.3    Sajedi, A.4    Smith, K.L.5    Parkinson, J.R.6
  • 11
    • 19344375318 scopus 로고    scopus 로고
    • Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
    • Chelikani P.K., Haver A.C., Reidelberger R.D. Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 2005, 288:R1695-R1706.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 14
    • 31044456099 scopus 로고    scopus 로고
    • Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
    • Knauf C., Cani P.D., Perrin C., Iglesias M.A., Maury J.F., Bernard E., et al. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage. J Clin Invest 2005, 115:3554-3563.
    • (2005) J Clin Invest , vol.115 , pp. 3554-3563
    • Knauf, C.1    Cani, P.D.2    Perrin, C.3    Iglesias, M.A.4    Maury, J.F.5    Bernard, E.6
  • 15
    • 0024836493 scopus 로고
    • Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide
    • Komatsu R., Matsuyama T., Namba M., Watanabe N., Itoh H., Kono N., et al. Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide. Diabetes 1989, 38:902-905.
    • (1989) Diabetes , vol.38 , pp. 902-905
    • Komatsu, R.1    Matsuyama, T.2    Namba, M.3    Watanabe, N.4    Itoh, H.5    Kono, N.6
  • 16
    • 47949104953 scopus 로고    scopus 로고
    • Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
    • Hayes M.R., Skibicka K.P., Grill H.J. Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation. Endocrinology 2008, 149:4059-4068.
    • (2008) Endocrinology , vol.149 , pp. 4059-4068
    • Hayes, M.R.1    Skibicka, K.P.2    Grill, H.J.3
  • 17
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes M.R., Bradley L., Grill H.J. Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 2009, 150:2654-2659.
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 18
    • 33845518516 scopus 로고    scopus 로고
    • Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
    • Williams D.L., Baskin D.G., Schwartz M.W. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes 2006, 55:3387-3393.
    • (2006) Diabetes , vol.55 , pp. 3387-3393
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 19
    • 17844399596 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors
    • Holst J.J., Deacon C.F. Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors. Diabetologia 2005, 48:612-615.
    • (2005) Diabetologia , vol.48 , pp. 612-615
    • Holst, J.J.1    Deacon, C.F.2
  • 20
    • 67649636449 scopus 로고    scopus 로고
    • Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
    • Ruttimann E.B., Arnold M., Hillebrand J.J., Geary N., Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009, 150:1174-1181.
    • (2009) Endocrinology , vol.150 , pp. 1174-1181
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 21
    • 0023008693 scopus 로고
    • Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing
    • Mojsov S., Heinrich G., Wilson I.B., Ravazzola M., Orci L., Habener J.F. Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem 1986, 261:11880-11889.
    • (1986) J Biol Chem , vol.261 , pp. 11880-11889
    • Mojsov, S.1    Heinrich, G.2    Wilson, I.B.3    Ravazzola, M.4    Orci, L.5    Habener, J.F.6
  • 22
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst J.J. The physiology of glucagon-like peptide 1. Physiol Rev 2007, 87:1409-1439.
    • (2007) Physiol Rev , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 24
    • 0033304603 scopus 로고    scopus 로고
    • The glucagon-like peptides
    • Kieffer T.J., Habener J.F. The glucagon-like peptides. Endocr Rev 1999, 20:876-913.
    • (1999) Endocr Rev , vol.20 , pp. 876-913
    • Kieffer, T.J.1    Habener, J.F.2
  • 25
    • 0026510891 scopus 로고
    • Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man
    • Eissele R., Goke R., Willemer S., Harthus H.P., Vermeer H., Arnold R., et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest 1992, 22:283-291.
    • (1992) Eur J Clin Invest , vol.22 , pp. 283-291
    • Eissele, R.1    Goke, R.2    Willemer, S.3    Harthus, H.P.4    Vermeer, H.5    Arnold, R.6
  • 27
    • 68649103260 scopus 로고    scopus 로고
    • T1r3 and alpha-gustducin in gut regulate secretion of glucagon-like peptide-1
    • Kokrashvili Z., Mosinger B., Margolskee R.F. T1r3 and alpha-gustducin in gut regulate secretion of glucagon-like peptide-1. Ann N Y Acad Sci 2009, 1170:91-94.
    • (2009) Ann N Y Acad Sci , vol.1170 , pp. 91-94
    • Kokrashvili, Z.1    Mosinger, B.2    Margolskee, R.F.3
  • 29
    • 2542497121 scopus 로고    scopus 로고
    • Gastrointestinal mechanisms of satiation for food
    • Ritter R.C. Gastrointestinal mechanisms of satiation for food. Physiol Behav 2004, 81:249-273.
    • (2004) Physiol Behav , vol.81 , pp. 249-273
    • Ritter, R.C.1
  • 30
    • 77953716554 scopus 로고    scopus 로고
    • Evidence that intestinal GLP-1 plays a physiological role in satiety
    • Williams D.L., Baskin D.G., Schwartz M.W. Evidence that intestinal GLP-1 plays a physiological role in satiety. Endocrinology 2008.
    • (2008) Endocrinology
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 31
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L., Klein E.J., Han J., Zhang B., Mac S.M., Poon T.H., et al. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab 2006, 8:436-447.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5    Poon, T.H.6
  • 32
    • 74549177233 scopus 로고    scopus 로고
    • A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus
    • Montanya E., Sesti G. A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus. Clin Ther 2009, 31:2472-2488.
    • (2009) Clin Ther , vol.31 , pp. 2472-2488
    • Montanya, E.1    Sesti, G.2
  • 33
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • Buse J.B., Rosenstock J., Sesti G., Schmidt W.E., Montanya E., Brett J.H., et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009, 374:39-47.
    • (2009) Lancet , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3    Schmidt, W.E.4    Montanya, E.5    Brett, J.H.6
  • 34
    • 34748898831 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
    • Vahl T.P., Tauchi M., Durler T.S., Elfers E.E., Fernandes T.M., Bitner R.D., et al. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 2007, 148:4965-4973.
    • (2007) Endocrinology , vol.148 , pp. 4965-4973
    • Vahl, T.P.1    Tauchi, M.2    Durler, T.S.3    Elfers, E.E.4    Fernandes, T.M.5    Bitner, R.D.6
  • 35
  • 36
    • 0033696456 scopus 로고    scopus 로고
    • Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms
    • Balkan B., Li X. Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms. Am J Physiol Regul Integr Comp Physiol 2000, 279:R1449-R1454.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Balkan, B.1    Li, X.2
  • 37
    • 0942287326 scopus 로고    scopus 로고
    • Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice
    • Ahren B. Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice. Am J Physiol Regul Integr Comp Physiol 2004, 286:R269-R272.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Ahren, B.1
  • 38
    • 0030572882 scopus 로고    scopus 로고
    • The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein
    • Nishizawa M., Nakabayashi H., Uchida K., Nakagawa A., Niijima A. The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein. J Auton Nerv Syst 1996, 61:149-154.
    • (1996) J Auton Nerv Syst , vol.61 , pp. 149-154
    • Nishizawa, M.1    Nakabayashi, H.2    Uchida, K.3    Nakagawa, A.4    Niijima, A.5
  • 39
    • 0025036101 scopus 로고
    • Central and peripheral vagal transport of cholecystokinin binding sites occurs in afferent fibers
    • Moran T.H., Norgren R., Crosby R.J., McHugh P.R. Central and peripheral vagal transport of cholecystokinin binding sites occurs in afferent fibers. Brain Res 1990, 526:95-102.
    • (1990) Brain Res , vol.526 , pp. 95-102
    • Moran, T.H.1    Norgren, R.2    Crosby, R.J.3    McHugh, P.R.4
  • 40
    • 17944365214 scopus 로고    scopus 로고
    • A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans
    • Verdich C., Flint A., Gutzwiller J.P., Naslund E., Beglinger C., Hellstrom P.M., et al. A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans. J Clin Endocrinol Metab 2001, 86:4382-4389.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4382-4389
    • Verdich, C.1    Flint, A.2    Gutzwiller, J.P.3    Naslund, E.4    Beglinger, C.5    Hellstrom, P.M.6
  • 41
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A., Raben A., Astrup A., Holst J.J. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998, 101:515-520.
    • (1998) J Clin Invest , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 42
    • 34548390977 scopus 로고    scopus 로고
    • The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
    • Scott K.A., Moran T.H. The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size. Am J Physiol Regul Integr Comp Physiol 2007, 293:R983-R987.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Scott, K.A.1    Moran, T.H.2
  • 43
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller J.P., Drewe J., Goke B., Schmidt H., Rohrer B., Lareida J., et al. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999, 276:R1541-R1544.
    • (1999) Am J Physiol , vol.276
    • Gutzwiller, J.P.1    Drewe, J.2    Goke, B.3    Schmidt, H.4    Rohrer, B.5    Lareida, J.6
  • 45
    • 74249117374 scopus 로고    scopus 로고
    • Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus
    • Freeman J.S. Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus. Cleve Clin J Med 2009, 76(Suppl 5):S12-S19.
    • (2009) Cleve Clin J Med , vol.76 , Issue.SUPPL. 5
    • Freeman, J.S.1
  • 46
    • 0036107064 scopus 로고    scopus 로고
    • Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice
    • Reimer M.K., Holst J.J., Ahren B. Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice. Eur J Endocrinol 2002, 146:717-727.
    • (2002) Eur J Endocrinol , vol.146 , pp. 717-727
    • Reimer, M.K.1    Holst, J.J.2    Ahren, B.3
  • 47
    • 0029958404 scopus 로고    scopus 로고
    • Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
    • Scrocchi L.A., Brown T.J., MaClusky N., Brubaker P.L., Auerbach A.B., Joyner A.L., et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996, 2:1254-1258.
    • (1996) Nat Med , vol.2 , pp. 1254-1258
    • Scrocchi, L.A.1    Brown, T.J.2    MaClusky, N.3    Brubaker, P.L.4    Auerbach, A.B.5    Joyner, A.L.6
  • 48
    • 0031731090 scopus 로고    scopus 로고
    • Effects of aging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 receptor -/- mice
    • Scrocchi L.A., Drucker D.J. Effects of aging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 receptor -/- mice. Endocrinology 1998, 139:3127-3132.
    • (1998) Endocrinology , vol.139 , pp. 3127-3132
    • Scrocchi, L.A.1    Drucker, D.J.2
  • 49
    • 11144244302 scopus 로고    scopus 로고
    • The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice
    • Lachey J.L., D'Alessio D.A., Rinaman L., Elmquist J.K., Drucker D.J., Seeley R.J. The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice. Endocrinology 2005, 146:458-462.
    • (2005) Endocrinology , vol.146 , pp. 458-462
    • Lachey, J.L.1    D'Alessio, D.A.2    Rinaman, L.3    Elmquist, J.K.4    Drucker, D.J.5    Seeley, R.J.6
  • 50
    • 77953703177 scopus 로고    scopus 로고
    • Pro-glucoagon-producing neurons in the nucleus of the solitary tract (NTS) are differentially regulated by leptin in mice and rats
    • Huo L., Grill H.J., Bjorbaek C. Pro-glucoagon-producing neurons in the nucleus of the solitary tract (NTS) are differentially regulated by leptin in mice and rats. Obesity (Nasso program abstract supplement) 2006, 14:A14.
    • (2006) Obesity (Nasso program abstract supplement) , vol.14
    • Huo, L.1    Grill, H.J.2    Bjorbaek, C.3
  • 51
    • 34447506584 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons
    • Wan S., Coleman F.H., Travagli R.A. Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons. Am J Physiol Gastrointest Liver Physiol 2007, 292:G1474-G1482.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Wan, S.1    Coleman, F.H.2    Travagli, R.A.3
  • 52
    • 0034639946 scopus 로고    scopus 로고
    • The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor
    • Nishizawa M., Nakabayashi H., Kawai K., Ito T., Kawakami S., Nakagawa A., et al. The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor. J Auton Nerv Syst 2000, 80:14-21.
    • (2000) J Auton Nerv Syst , vol.80 , pp. 14-21
    • Nishizawa, M.1    Nakabayashi, H.2    Kawai, K.3    Ito, T.4    Kawakami, S.5    Nakagawa, A.6
  • 53
    • 77953713440 scopus 로고    scopus 로고
    • Intrameal Hepatic-Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 (GLP-1) Reduce Spontaneous Meal Size in the Rat via Different Mechanisms
    • Ruttimann E.B., Arnold M., Hillebrand J.J., Geary N., Langhans W. Intrameal Hepatic-Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 (GLP-1) Reduce Spontaneous Meal Size in the Rat via Different Mechanisms. Endocrinology 2008.
    • (2008) Endocrinology
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 55
    • 0346995398 scopus 로고    scopus 로고
    • Sensory circumventricular organs: central roles in integrated autonomic regulation
    • Cottrell G.T., Ferguson A.V. Sensory circumventricular organs: central roles in integrated autonomic regulation. Regul Pept 2004, 117:11-23.
    • (2004) Regul Pept , vol.117 , pp. 11-23
    • Cottrell, G.T.1    Ferguson, A.V.2
  • 56
    • 77949837737 scopus 로고    scopus 로고
    • Lesions of Area Postrema and Subfornical Organ Alter Exendin-4-Induced Brain Activation without Preventing the Hypophagic Effect of the Glp-1 Receptor Agonist
    • Baraboi E.D., Smith P., Ferguson A.V., Richard D. Lesions of Area Postrema and Subfornical Organ Alter Exendin-4-Induced Brain Activation without Preventing the Hypophagic Effect of the Glp-1 Receptor Agonist. Am J Physiol Regul Integr Comp Physiol. 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol.
    • Baraboi, E.D.1    Smith, P.2    Ferguson, A.V.3    Richard, D.4
  • 58
    • 70249091762 scopus 로고    scopus 로고
    • Comparison of weight loss and body composition changes with four surgical procedures
    • Strain G.W., Gagner M., Pomp A., Dakin G., Inabnet W.B., Hsieh J., et al. Comparison of weight loss and body composition changes with four surgical procedures. Surg Obes Relat Dis 2009, 5:582-587.
    • (2009) Surg Obes Relat Dis , vol.5 , pp. 582-587
    • Strain, G.W.1    Gagner, M.2    Pomp, A.3    Dakin, G.4    Inabnet, W.B.5    Hsieh, J.6
  • 59
    • 68949094297 scopus 로고    scopus 로고
    • Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial
    • Peterli R., Wolnerhanssen B., Peters T., Devaux N., Kern B., Christoffel-Courtin C., et al. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg 2009, 250:234-241.
    • (2009) Ann Surg , vol.250 , pp. 234-241
    • Peterli, R.1    Wolnerhanssen, B.2    Peters, T.3    Devaux, N.4    Kern, B.5    Christoffel-Courtin, C.6
  • 60
    • 42249100525 scopus 로고    scopus 로고
    • Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study
    • Karamanakos S.N., Vagenas K., Kalfarentzos F., Alexandrides T.K. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg 2008, 247:401-407.
    • (2008) Ann Surg , vol.247 , pp. 401-407
    • Karamanakos, S.N.1    Vagenas, K.2    Kalfarentzos, F.3    Alexandrides, T.K.4
  • 61
    • 77953693358 scopus 로고    scopus 로고
    • The Management of Mood Disorders with Anti-depressant Medications After Bariatric Surgery. Current Psychiatry (in press).
    • Sarwer DB, Faulconbridge LF, Steffen KJ, Roerig JL, Mitchell JE. The Management of Mood Disorders with Anti-depressant Medications After Bariatric Surgery. Current Psychiatry (in press).
    • Sarwer, D.B.1    Faulconbridge, L.F.2    Steffen, K.J.3    Roerig, J.L.4    Mitchell, J.E.5
  • 62
    • 77649136496 scopus 로고    scopus 로고
    • Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of action
    • Rubino F., Schauer P.R., Kaplan L.M., Cummings D.E. Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of action. Annu Rev Med 2010, 61:393-411.
    • (2010) Annu Rev Med , vol.61 , pp. 393-411
    • Rubino, F.1    Schauer, P.R.2    Kaplan, L.M.3    Cummings, D.E.4
  • 63
    • 61549094077 scopus 로고    scopus 로고
    • Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis
    • e5
    • Buchwald H., Estok R., Fahrbach K., Banel D., Jensen M.D., Pories W.J., et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009, 122:248-256. e5.
    • (2009) Am J Med , vol.122 , pp. 248-256
    • Buchwald, H.1    Estok, R.2    Fahrbach, K.3    Banel, D.4    Jensen, M.D.5    Pories, W.J.6
  • 64
  • 65
    • 70349506347 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats
    • Stylopoulos N., Hoppin A.G., Kaplan L.M. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity (Silver Spring) 2009, 17:1839-1847.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1839-1847
    • Stylopoulos, N.1    Hoppin, A.G.2    Kaplan, L.M.3
  • 67
    • 36048950771 scopus 로고    scopus 로고
    • Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding
    • Korner J., Bessler M., Inabnet W., Taveras C., Holst J.J. Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding. Surg Obes Relat Dis 2007, 3:597-601.
    • (2007) Surg Obes Relat Dis , vol.3 , pp. 597-601
    • Korner, J.1    Bessler, M.2    Inabnet, W.3    Taveras, C.4    Holst, J.J.5
  • 68
    • 0033565253 scopus 로고    scopus 로고
    • The enteric nervous system: a second brain
    • 5-8, 41-2 passim
    • Gershon M.D. The enteric nervous system: a second brain. Hosp Pract (Minneap) 1999, 34:31-32. 5-8, 41-2 passim.
    • (1999) Hosp Pract (Minneap) , vol.34 , pp. 31-32
    • Gershon, M.D.1
  • 69
    • 2342481083 scopus 로고    scopus 로고
    • Sensory mechanisms: transmitters, modulators and reflexes
    • Raybould H.E., Cooke H.J., Christofi F.L. Sensory mechanisms: transmitters, modulators and reflexes. Neurogastroenterol Motil 2004, 16(Suppl 1):60-63.
    • (2004) Neurogastroenterol Motil , vol.16 , Issue.SUPPL. 1 , pp. 60-63
    • Raybould, H.E.1    Cooke, H.J.2    Christofi, F.L.3
  • 70
    • 70350380343 scopus 로고    scopus 로고
    • Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism
    • Kindel T.L., Yoder S.M., Seeley R.J., D'Alessio D.A., Tso P. Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. J Gastrointest Surg 2009, 13:1762-1772.
    • (2009) J Gastrointest Surg , vol.13 , pp. 1762-1772
    • Kindel, T.L.1    Yoder, S.M.2    Seeley, R.J.3    D'Alessio, D.A.4    Tso, P.5
  • 71
    • 33845940661 scopus 로고    scopus 로고
    • GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects
    • Morinigo R., Lacy A.M., Casamitjana R., Delgado S., Gomis R., Vidal J. GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects. Obes Surg 2006, 16:1594-1601.
    • (2006) Obes Surg , vol.16 , pp. 1594-1601
    • Morinigo, R.1    Lacy, A.M.2    Casamitjana, R.3    Delgado, S.4    Gomis, R.5    Vidal, J.6
  • 72
    • 33646411242 scopus 로고    scopus 로고
    • Glucagon-like peptide-1, peptide YY, hunger, and satiety after gastric bypass surgery in morbidly obese subjects
    • Morinigo R., Moize V., Musri M., Lacy A.M., Navarro S., Marin J.L., et al. Glucagon-like peptide-1, peptide YY, hunger, and satiety after gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab 2006, 91:1735-1740.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1735-1740
    • Morinigo, R.1    Moize, V.2    Musri, M.3    Lacy, A.M.4    Navarro, S.5    Marin, J.L.6
  • 74
    • 23844446798 scopus 로고    scopus 로고
    • Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system
    • Osaka T., Endo M., Yamakawa M., Inoue S. Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system. Peptides 2005, 26:1623-1631.
    • (2005) Peptides , vol.26 , pp. 1623-1631
    • Osaka, T.1    Endo, M.2    Yamakawa, M.3    Inoue, S.4
  • 75
    • 0036307872 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
    • Yamamoto H., Lee C.E., Marcus J.N., Williams T.D., Overton J.M., Lopez M.E., et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest 2002, 110:43-52.
    • (2002) J Clin Invest , vol.110 , pp. 43-52
    • Yamamoto, H.1    Lee, C.E.2    Marcus, J.N.3    Williams, T.D.4    Overton, J.M.5    Lopez, M.E.6
  • 76
    • 0032714917 scopus 로고    scopus 로고
    • Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats
    • Barragan J.M., Eng J., Rodriguez R., Blazquez E. Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats. Am J Physiol 1999, 277:E784-E791.
    • (1999) Am J Physiol , vol.277
    • Barragan, J.M.1    Eng, J.2    Rodriguez, R.3    Blazquez, E.4
  • 77
    • 0030583731 scopus 로고    scopus 로고
    • Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats
    • Barragan J.M., Rodriguez R.E., Eng J., Blazquez E. Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats. Regul Pept 1996, 67:63-68.
    • (1996) Regul Pept , vol.67 , pp. 63-68
    • Barragan, J.M.1    Rodriguez, R.E.2    Eng, J.3    Blazquez, E.4
  • 78
    • 33748118597 scopus 로고    scopus 로고
    • Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures
    • Mack C.M., Moore C.X., Jodka C.M., Bhavsar S., Wilson J.K., Hoyt J.A., et al. Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures. Int J Obes (Lond) 2006, 30:1332-1340.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1332-1340
    • Mack, C.M.1    Moore, C.X.2    Jodka, C.M.3    Bhavsar, S.4    Wilson, J.K.5    Hoyt, J.A.6
  • 79
    • 0017887676 scopus 로고
    • Projections from the nucleus of the solitary tract in the rat
    • Norgren R. Projections from the nucleus of the solitary tract in the rat. Neuroscience 1978, 3:207-218.
    • (1978) Neuroscience , vol.3 , pp. 207-218
    • Norgren, R.1
  • 80
    • 0015885866 scopus 로고
    • Ascending central gustatory pathways
    • Norgren R., Leonard C.M. Ascending central gustatory pathways. J Comp Neurol 1973, 150:217-237.
    • (1973) J Comp Neurol , vol.150 , pp. 217-237
    • Norgren, R.1    Leonard, C.M.2
  • 81
    • 33749478768 scopus 로고    scopus 로고
    • Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging
    • Chaudhri O.B., Parkinson J.R., Kuo Y.T., Druce M.R., Herlihy A.H., Bell J.D., et al. Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging. Biochem Biophys Res Commun 2006, 350:298-306.
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 298-306
    • Chaudhri, O.B.1    Parkinson, J.R.2    Kuo, Y.T.3    Druce, M.R.4    Herlihy, A.H.5    Bell, J.D.6
  • 82
    • 0037349072 scopus 로고    scopus 로고
    • Entry of exendin-4 into brain is rapid but may be limited at high doses
    • Kastin A.J., Akerstrom V. Entry of exendin-4 into brain is rapid but may be limited at high doses. Int J Obes Relat Metab Disord 2003, 27:313-318.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 313-318
    • Kastin, A.J.1    Akerstrom, V.2
  • 83
    • 34447134870 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 stimulates hypothalamic proopiomelanocortin neurons
    • Ma X., Bruning J., Ashcroft F.M. Glucagon-like peptide 1 stimulates hypothalamic proopiomelanocortin neurons. J Neurosci 2007, 27:7125-7129.
    • (2007) J Neurosci , vol.27 , pp. 7125-7129
    • Ma, X.1    Bruning, J.2    Ashcroft, F.M.3
  • 84
    • 0017887417 scopus 로고
    • Neurological tests and behavioral deficits in chronic thalamic and chronic decerebrate rats
    • Grill H.J., Norgren R. Neurological tests and behavioral deficits in chronic thalamic and chronic decerebrate rats. Brain Res 1978, 143:299-312.
    • (1978) Brain Res , vol.143 , pp. 299-312
    • Grill, H.J.1    Norgren, R.2
  • 85
    • 13344282056 scopus 로고    scopus 로고
    • A role for glucagon-like peptide-1 in the central regulation of feeding
    • Turton M.D., O'Shea D., Gunn I., Beak S.A., Edwards C.M., Meeran K., et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996, 379:69-72.
    • (1996) Nature , vol.379 , pp. 69-72
    • Turton, M.D.1    O'Shea, D.2    Gunn, I.3    Beak, S.A.4    Edwards, C.M.5    Meeran, K.6
  • 86
    • 0032940582 scopus 로고    scopus 로고
    • Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat
    • Meeran K., O'Shea D., Edwards C.M., Turton M.D., Heath M.M., Gunn I., et al. Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat. Endocrinology 1999, 140:244-250.
    • (1999) Endocrinology , vol.140 , pp. 244-250
    • Meeran, K.1    O'Shea, D.2    Edwards, C.M.3    Turton, M.D.4    Heath, M.M.5    Gunn, I.6
  • 87
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes M.R., Bradley L., Grill H.J. Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 2009, 150(6):2654-2659.
    • (2009) Endocrinology , vol.150 , Issue.6 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 88
    • 0036142589 scopus 로고    scopus 로고
    • Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake
    • Grill H.J., Schwartz M.W., Kaplan J.M., Foxhall J.S., Breininger J., Baskin D.G. Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology 2002, 143:239-246.
    • (2002) Endocrinology , vol.143 , pp. 239-246
    • Grill, H.J.1    Schwartz, M.W.2    Kaplan, J.M.3    Foxhall, J.S.4    Breininger, J.5    Baskin, D.G.6
  • 89
    • 33646550541 scopus 로고    scopus 로고
    • Gastric distension enhances CCK-induced Fos-like immunoreactivity in the dorsal hindbrain by activating 5-HT3 receptors
    • Hayes M.R., Covasa M. Gastric distension enhances CCK-induced Fos-like immunoreactivity in the dorsal hindbrain by activating 5-HT3 receptors. Brain Res 2006, 1088:120-130.
    • (2006) Brain Res , vol.1088 , pp. 120-130
    • Hayes, M.R.1    Covasa, M.2
  • 90
    • 34249785695 scopus 로고    scopus 로고
    • Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin
    • Huo L., Maeng L., Bjorbaek C., Grill H.J. Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin. Endocrinology 2007, 148:2189-2197.
    • (2007) Endocrinology , vol.148 , pp. 2189-2197
    • Huo, L.1    Maeng, L.2    Bjorbaek, C.3    Grill, H.J.4
  • 91
    • 0029655821 scopus 로고    scopus 로고
    • The direct and indirect controls of meal size
    • Smith G.P. The direct and indirect controls of meal size. Neurosci Biobehav Rev 1996, 20:41-46.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 41-46
    • Smith, G.P.1
  • 92
    • 0024333756 scopus 로고
    • Ultrastructural demonstration of a gastric monosynaptic vagal circuit in the nucleus of the solitary tract in rat
    • Rinaman L., Card J.P., Schwaber J.S., Miselis R.R. Ultrastructural demonstration of a gastric monosynaptic vagal circuit in the nucleus of the solitary tract in rat. J Neurosci 1989, 9:1985-1996.
    • (1989) J Neurosci , vol.9 , pp. 1985-1996
    • Rinaman, L.1    Card, J.P.2    Schwaber, J.S.3    Miselis, R.R.4
  • 93
    • 77953718453 scopus 로고    scopus 로고
    • The NTS: A portal for visceral afferent signal processing, energy status assessment, and integrator of their combined effects on food intake. Int J Obes..
    • Grill HJ, Hayes MR. The NTS: A portal for visceral afferent signal processing, energy status assessment, and integrator of their combined effects on food intake. Int J Obes. 2008.
    • (2008)
    • Grill, H.J.1    Hayes, M.R.2
  • 95
    • 0034507515 scopus 로고    scopus 로고
    • Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function
    • Perfetti R., Merkel P. Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function. Eur J Endocrinol 2000, 143:717-725.
    • (2000) Eur J Endocrinol , vol.143 , pp. 717-725
    • Perfetti, R.1    Merkel, P.2
  • 96
    • 0037073717 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells
    • Gomez E., Pritchard C., Herbert T.P. cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells. J Biol Chem 2002, 277:48146-48151.
    • (2002) J Biol Chem , vol.277 , pp. 48146-48151
    • Gomez, E.1    Pritchard, C.2    Herbert, T.P.3
  • 97
    • 0030963439 scopus 로고    scopus 로고
    • CAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler M.R., Yao H., York R.D., Pan M.G., Rim C.S., Stork P.J. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 1997, 89:73-82.
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.6
  • 98
    • 0033520311 scopus 로고    scopus 로고
    • Differential effects of cAMP in neurons and astrocytes. Role of B-raf
    • Dugan L.L., Kim J.S., Zhang Y., Bart R.D., Sun Y., Holtzman D.M., et al. Differential effects of cAMP in neurons and astrocytes. Role of B-raf. J Biol Chem 1999, 274:25842-25848.
    • (1999) J Biol Chem , vol.274 , pp. 25842-25848
    • Dugan, L.L.1    Kim, J.S.2    Zhang, Y.3    Bart, R.D.4    Sun, Y.5    Holtzman, D.M.6
  • 99
    • 33845972272 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
    • Hurley R.L., Barre L.K., Wood S.D., Anderson K.A., Kemp B.E., Means A.R., et al. Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP. J Biol Chem 2006, 281:36662-36672.
    • (2006) J Biol Chem , vol.281 , pp. 36662-36672
    • Hurley, R.L.1    Barre, L.K.2    Wood, S.D.3    Anderson, K.A.4    Kemp, B.E.5    Means, A.R.6
  • 100
    • 33745204479 scopus 로고    scopus 로고
    • AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
    • Xue B., Kahn B.B. AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol 2006, 574:73-83.
    • (2006) J Physiol , vol.574 , pp. 73-83
    • Xue, B.1    Kahn, B.B.2
  • 101
    • 1842484296 scopus 로고    scopus 로고
    • AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    • Minokoshi Y., Alquier T., Furukawa N., Kim Y.B., Lee A., Xue B., et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004, 428:569-574.
    • (2004) Nature , vol.428 , pp. 569-574
    • Minokoshi, Y.1    Alquier, T.2    Furukawa, N.3    Kim, Y.B.4    Lee, A.5    Xue, B.6
  • 102
    • 55049140818 scopus 로고    scopus 로고
    • Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats
    • Seo S., Ju S., Chung H., Lee D., Park S. Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats. Endocr J 2008, 55:867-874.
    • (2008) Endocr J , vol.55 , pp. 867-874
    • Seo, S.1    Ju, S.2    Chung, H.3    Lee, D.4    Park, S.5
  • 103
    • 0038584871 scopus 로고    scopus 로고
    • Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
    • da Silva Xavier G., Leclerc I., Varadi A., Tsuboi T., Moule S.K., Rutter G.A. Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression. Biochem J 2003, 371:761-774.
    • (2003) Biochem J , vol.371 , pp. 761-774
    • da Silva Xavier, G.1    Leclerc, I.2    Varadi, A.3    Tsuboi, T.4    Moule, S.K.5    Rutter, G.A.6
  • 104
    • 23744515608 scopus 로고    scopus 로고
    • Role of hypothalamic 5'-AMP-activated protein kinase in the regulation of food intake and energy homeostasis
    • Kim M.S., Lee K.U. Role of hypothalamic 5'-AMP-activated protein kinase in the regulation of food intake and energy homeostasis. J Mol Med 2005, 83:514-520.
    • (2005) J Mol Med , vol.83 , pp. 514-520
    • Kim, M.S.1    Lee, K.U.2
  • 105
    • 3142677140 scopus 로고    scopus 로고
    • Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
    • Kim M.S., Park J.Y., Namkoong C., Jang P.G., Ryu J.W., Song H.S., et al. Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 2004, 10:727-733.
    • (2004) Nat Med , vol.10 , pp. 727-733
    • Kim, M.S.1    Park, J.Y.2    Namkoong, C.3    Jang, P.G.4    Ryu, J.W.5    Song, H.S.6
  • 106
    • 26244461692 scopus 로고    scopus 로고
    • Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats
    • Han S.M., Namkoong C., Jang P.G., Park I.S., Hong S.W., Katakami H., et al. Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats. Diabetologia 2005, 48:2170-2178.
    • (2005) Diabetologia , vol.48 , pp. 2170-2178
    • Han, S.M.1    Namkoong, C.2    Jang, P.G.3    Park, I.S.4    Hong, S.W.5    Katakami, H.6
  • 109
    • 40749157994 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide-mediated up-regulation of beta-cell antiapoptotic Bcl-2 gene expression is coordinated by cyclic AMP (cAMP) response element binding protein (CREB) and cAMP-responsive CREB coactivator 2
    • Kim S.J., Nian C., Widenmaier S., McIntosh C.H. Glucose-dependent insulinotropic polypeptide-mediated up-regulation of beta-cell antiapoptotic Bcl-2 gene expression is coordinated by cyclic AMP (cAMP) response element binding protein (CREB) and cAMP-responsive CREB coactivator 2. Mol Cell Biol 2008, 28:1644-1656.
    • (2008) Mol Cell Biol , vol.28 , pp. 1644-1656
    • Kim, S.J.1    Nian, C.2    Widenmaier, S.3    McIntosh, C.H.4
  • 110
    • 23844542825 scopus 로고    scopus 로고
    • Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through extracellular signal-regulated kinase signaling in rat solitary nucleus
    • Sutton G.M., Duos B., Patterson L.M., Berthoud H.R. Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through extracellular signal-regulated kinase signaling in rat solitary nucleus. Endocrinology 2005, 146:3739-3747.
    • (2005) Endocrinology , vol.146 , pp. 3739-3747
    • Sutton, G.M.1    Duos, B.2    Patterson, L.M.3    Berthoud, H.R.4
  • 111
    • 64949116079 scopus 로고    scopus 로고
    • The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake
    • Grill H.J., Hayes M.R. The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake. Int J Obes (Lond) 2009, 33(Suppl 1):S11-S15.
    • (2009) Int J Obes (Lond) , vol.33 , Issue.SUPPL. 1
    • Grill, H.J.1    Hayes, M.R.2
  • 112
    • 72449121795 scopus 로고    scopus 로고
    • Leptin and the systems neuroscience of meal size control
    • Grill H.J. Leptin and the systems neuroscience of meal size control. Front Neuroendocrinol 2010, 31:61-78.
    • (2010) Front Neuroendocrinol , vol.31 , pp. 61-78
    • Grill, H.J.1
  • 113
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud H.R. Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 2002, 26:393-428.
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 393-428
    • Berthoud, H.R.1
  • 114
  • 115
    • 58749086043 scopus 로고    scopus 로고
    • The geometry of leptin action in the brain: more complicated than a simple ARC
    • Myers M.G., Munzberg H., Leinninger G.M., Leshan R.L. The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab 2009, 9:117-123.
    • (2009) Cell Metab , vol.9 , pp. 117-123
    • Myers, M.G.1    Munzberg, H.2    Leinninger, G.M.3    Leshan, R.L.4
  • 116
    • 67849085498 scopus 로고    scopus 로고
    • Leptin taking the path less traveled
    • DiLeone R.J. Leptin taking the path less traveled. Cell Metab 2009, 10:77-78.
    • (2009) Cell Metab , vol.10 , pp. 77-78
    • DiLeone, R.J.1
  • 117
    • 34249853509 scopus 로고    scopus 로고
    • Gut peptide signaling in the controls of food intake
    • Moran T.H. Gut peptide signaling in the controls of food intake. Obesity (Silver Spring) 2006, 14(Suppl 5):250S-253S.
    • (2006) Obesity (Silver Spring) , vol.14 , Issue.SUPPL. 5
    • Moran, T.H.1
  • 118
    • 34347345996 scopus 로고    scopus 로고
    • Brain-adipose tissue neural crosstalk
    • Bartness T.J., Song C.K. Brain-adipose tissue neural crosstalk. Physiol Behav 2007, 91:343-351.
    • (2007) Physiol Behav , vol.91 , pp. 343-351
    • Bartness, T.J.1    Song, C.K.2
  • 119
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice
    • Talsania T., Anini Y., Siu S., Drucker D.J., Brubaker P.L. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 2005, 146:3748-3756.
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 120
  • 121
    • 0031590319 scopus 로고    scopus 로고
    • Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents
    • Goldstone A.P., Mercer J.G., Gunn I., Moar K.M., Edwards C.M., Rossi M., et al. Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents. FEBS Lett 1997, 415:134-138.
    • (1997) FEBS Lett , vol.415 , pp. 134-138
    • Goldstone, A.P.1    Mercer, J.G.2    Gunn, I.3    Moar, K.M.4    Edwards, C.M.5    Rossi, M.6
  • 123
    • 34347406528 scopus 로고    scopus 로고
    • Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat
    • Bojanowska E., Nowak A. Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat. J Physiol Pharmacol 2007, 58:349-360.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 349-360
    • Bojanowska, E.1    Nowak, A.2
  • 125
    • 0031470983 scopus 로고    scopus 로고
    • Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake
    • Matson C.A., Wiater M.F., Kuijper J.L., Weigle D.S. Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake. Peptides 1997, 18:1275-1278.
    • (1997) Peptides , vol.18 , pp. 1275-1278
    • Matson, C.A.1    Wiater, M.F.2    Kuijper, J.L.3    Weigle, D.S.4
  • 127
    • 72649103549 scopus 로고    scopus 로고
    • Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation
    • Hayes M.R., Skibicka K.P., Leichner T.M., Guarnieri D.J., DiLeone R.J., Bence K.K., et al. Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation. Cell Metab 2010, 11:77-83.
    • (2010) Cell Metab , vol.11 , pp. 77-83
    • Hayes, M.R.1    Skibicka, K.P.2    Leichner, T.M.3    Guarnieri, D.J.4    DiLeone, R.J.5    Bence, K.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.