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Volumn 76, Issue 2, 2010, Pages 410-420
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Study of surfactant combinations and development of a novel nanoemulsion for minimising variations in bioavailability of ezetimibe
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Author keywords
Ezetimibe; Nanoemulsion; Oral bioavailability; Pseudoternary phase diagram; Solubility; Stability
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Indexed keywords
EZETIMIBE;
NANOEMULSION;
ORAL BIOAVAILABILITY;
PSEUDOTERNARY PHASE DIAGRAM;
PSEUDOTERNARY PHASE DIAGRAMS;
BIOCHEMISTRY;
DISSOLUTION;
OPTIMIZATION;
PHASE DIAGRAMS;
POLYETHYLENE GLYCOLS;
REFRACTIVE INDEX;
SOLUBILITY;
STABILITY;
SURFACE ACTIVE AGENTS;
TERNARY SYSTEMS;
ZETA POTENTIAL;
SUSPENSIONS (FLUIDS);
CHOLESTEROL;
COSURFACTANT;
EZETIMIBE;
NONIONIC SURFACTANT;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
CHOLESTEROL BLOOD LEVEL;
CONTROLLED STUDY;
DOSE RESPONSE;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG DOSAGE FORM COMPARISON;
DRUG FORMULATION;
DRUG RELEASE;
DRUG SOLUBILITY;
DRUG STABILITY;
HYPERLIPIDEMIA;
IN VITRO STUDY;
IN VIVO STUDY;
NANOEMULSION;
NONHUMAN;
PARTICLE SIZE;
PHARMACODYNAMICS;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
PROCESS OPTIMIZATION;
RAT;
REFRACTION INDEX;
ROOM TEMPERATURE;
SHELF LIFE;
SUSPENSION;
TABLET;
THERMODYNAMICS;
THERMOSTABILITY;
TRANSMISSION ELECTRON MICROSCOPY;
VISCOSITY;
ZETA POTENTIAL;
ANIMALS;
AZETIDINES;
CHOLESTEROL;
DRUG STABILITY;
EMULSIONS;
LIPOPROTEINS, HDL;
NANOPARTICLES;
PARTICLE SIZE;
RATS;
RATS, WISTAR;
SOLUBILITY;
SURFACE PROPERTIES;
SURFACE-ACTIVE AGENTS;
THERMODYNAMICS;
TISSUE DISTRIBUTION;
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EID: 75749112825
PISSN: 09277765
EISSN: None
Source Type: Journal
DOI: 10.1016/j.colsurfb.2009.11.021 Document Type: Article |
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Times cited : (218)
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References (25)
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