Farnesoid X Receptor-Induced Lysine-Specific Histone Demethylase Reduces Hepatic Bile Acid Levels and Protects the Liver Against Bile Acid Toxicity

Hepatology

Volumn 62, Issue 1, 2015, Pages 220-231

  Kim, Young Chae ^a   Fang, Sungsoon ^a,b   Byun, Sangwon ^a   Seok, Sunmi ^a   Kemper, Byron ^a   Kemper, Jongsook Kim ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; CYTOCHROME P450; CYTOCHROME P450 8B1; FARNESOID X RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE 1; HISTONE H3; LYSINE; MESSENGER RNA; MESSENGER RNA PRECURSOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RETINOID X RECEPTOR ALPHA; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; AOF2 PROTEIN, MOUSE; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; NUCLEAR RECEPTOR SUBFAMILY 0, GROUP B, MEMBER 2;

ADENOVIRIDAE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID LIVER LEVEL; CONTROLLED STUDY; DEACETYLATION; DETOXIFICATION; DOWN REGULATION; EPIGENETICS; GENE ACTIVATION; GENE EXPRESSION; GENE REPRESSION; HISTONE DEMETHYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; IN VIVO STUDY; INTRON; LIVER LEVEL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; TRANSACTIVATION; ANIMAL; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; KNOCKOUT MOUSE; LIVER; METABOLISM;

ANIMALS; BILE ACIDS AND SALTS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONE DEMETHYLASES; LIVER; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84932625777     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27677     Document Type: Article

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