Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

Hepatology

Volumn 56, Issue 1, 2012, Pages 108-117

  Lee, Jiyoung ^a   Seok, Sunmi ^a   Yu, Pengfei ^b   Kim, Kyungsu ^b   Smith, Zachary ^a   Rivas Astroza, Marcelo ^b   Zhong, Sheng ^b   Kemper, Jongsook Kim ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; AMINO ACID; FARNESOID X RECEPTOR; MESSENGER RNA; RNA POLYMERASE II;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE ACTIVATION; GENE REPRESSION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HYPOXIA; INFLAMMATION; INTRON; LIVER; LIVER CELL; LIVER FUNCTION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BINDING; RNA PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BINDING SITES; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENOME; LIVER; MALE; MICE; MICE, INBRED BALB C; OBESITY; RANDOM ALLOCATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84863512181     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25609     Document Type: Article

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