Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Ouyang, Huafang ^a   Qin, Yi ^a   Liu, Yanfeng ^b   Xie, Youhua ^a,b   Liu, Jing ^b  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HISTONE DEACETYLASE 2; NUCLEOSOME REMODELING AND HISTONE DEACETYLASE; PROX1 PROTEIN; RETINOBLASTOMA BINDING PROTEIN 2; RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CYP7A1 PROTEIN, HUMAN; HISTONE DEACETYLASE; HISTONE DEMETHYLASE; HOMEODOMAIN PROTEIN; KDM1A PROTEIN, HUMAN; PROSPERO-RELATED HOMEOBOX 1 PROTEIN; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; CELL STRAIN HEPG2; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEMETHYLATION; EPIGENETIC REPRESSION; EPIGENETICS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL; MASS SPECTROMETRY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; RNA ISOLATION; ANIMAL; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HEPG2 CELL LINE; METABOLISM; PROMOTER REGION;

PROSPERO;

ANIMALS; BILE ACIDS AND SALTS; CELL LINE; CHOLESTEROL 7-ALPHA-HYDROXYLASE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HEP G2 CELLS; HISTONE DEMETHYLASES; HOMEODOMAIN PROTEINS; HUMANS; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84876553118     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062192     Document Type: Article

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