Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP

Molecular and Cellular Biology

Volumn 24, Issue 17, 2004, Pages 7707-7719

  Kemper, Jongsook Kim ^a   Kim, Hwajin ^a   Miao, Ji ^b   Bhalla, Sonali ^a   Bae, Yangjin ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BILE ACID; PROTEIN BRM; PROTEIN SHP; RECEPTOR PROTEIN; TRANSCRIPTION FACTOR SIN3A; UNCLASSIFIED DRUG;

ARTICLE; BILE ACID SYNTHESIS; CHOLESTEROL METABOLISM; CHROMATIN STRUCTURE; CYP7A1 GENE; FEEDBACK SYSTEM; GENE; GENE EXPRESSION REGULATION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYLTRANSFERASES; ADENOSINE TRIPHOSPHATASES; BILE ACIDS AND SALTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DROSOPHILA PROTEINS; FEEDBACK, BIOCHEMICAL; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; HUMANS; MACROMOLECULAR SUBSTANCES; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 4344601668     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.17.7707-7719.2004     Document Type: Article

References (56)

1. Bae, Y., J. K. Kemper, and B. Kemper. 2004. Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP). DNA Cell Biol. 23:81-91.
2. Borgius, L. J., K. R. Steffensen, J. A. Gustafsson, and E. Treuter. 2002. Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP. J. Biol. Chem. 277:49761-49766.
3. Brendel, C., K. Schoonjans, O. A. Botrugno, E. Treuter, and J. Auwerx. 2002. The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity. Mol. Endocrinol. 16:2065-2076.
4. Burakov, D., L. Crofts, C. Chang, and L. Freedman. 2002. Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. J. Biol. Chem. 277:14359-14362.
5. Chen, F., L. Ma, P. A. Dawson, C. J. Sinal, E. Sehayek, F. J. Gonzalez, J. Breslow, M. Ananthanarayanan. and B. L. Shneider. 2003. Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. J. Biol. Chem. 278:19909-19916.
6. Chiang, J. Y. L., R. Kimmel, C. Weinberger, and D. Stroup. 2000. Farnesoid X receptor responds to bile acids and represses cholesterol 7a-hydroxylase gene (CYP7A1) transcription. J. Biol. Chem. 275:10918-10924.
7. Chiang, J. Y. L., and D. Stroup. 1994. Identification and characterization of a putative bile acid-responsive element in cholesterol 7a-hydroxylase gene promoter. J. Biol. Chem. 269:17502-17507.
8. De Fabiani, E., N. Mitro, A. Anzulovich, A. Pinelli, G. Galli, and M. Crestani. 2001. The negative effects of bile acids and tumor necrosis factor-α on the transcription of cholesterol 7-α hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4. J. Biol. Chem. 276:30708-30716.
9. de la Serna, I. L., K. A. Carlson, and A. N. Imbalzano. 2001. Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat. Genet. 27:187-190.
10. de la Serna, I. L., K. Roy, K. A. Carlson, and A. N. Imbalzano. 2001. MyoD can induce cell cycle arrest but not muscle differentiation in the presence of dominant negative SWI/SNF chromatin remodeling enzymes. J. Biol. Chem. 276:41486-41491.
11. del Castillo-Olivares, A., and G. Gil. 2000. Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7a-hydroxylase transcription. Nucleic Acids Res. 28:3587-3593.
12. Denson, L. A., E. Sturm, W. Echevarria, T. L. Zimmerman, M. Makishima, D. J. Mangelsdorf, and S. J. Karpen. 2001. The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Gastroenterology 121:140-147.
13. DiRenzo, J., Y. Shang, M. Phelan, S. Sif, M. Myers, R. Kingston, and M. Brown. 2000. BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Mol. Cell. Biol. 20:7541-7549.
14. Fryer, C. J., and T. K. Archer. 1998. Chromatin remodeling by the glucocorticoid receptor requires the BRG1 complex. Nature 393:88-91.
15. Goodwin, B., S. A. Jones, R. R. Price, M. A. Watson, D. D. McKee, L. B. Moore, C. Galardi, J. G. Wilson, M. C. Lewis, M. E. Roth, P. R. Maloney, T. M. Wilson, and S. A. Kliewer. 2000. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol. Cell 6:517-526.
16. Gupta, S., T. Stravitz, P. Dent, and P. Hylemon. 2001. Down-regulation of cholesterol 7 a-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-jun N-terminal kinase pathway. J. Biol. Chem. 276:15816-15822.
17. Hayhurst, G., Y. Lee, G. Lambert, J. Ward, and F. J. Gonzalez. 2001. Hepatocyte nuclear factor 4a (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol. Cell. Biol. 21:1393-1403.
18. Ho, M., R. Yu, and J. L. Jameson. 1997. DAX-1 inhibits SF-1 mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita. Mol. Cell. Biol. 17:1476-1483.
19. Johansson, L., J. S. Thomsen, A. E. Damdimopoulos, G. Spyrou, J.-A. Gustafsson, and E. Treuter. 1999. The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERα and ERβ. J. Biol. Chem. 274:345-353.
20. Kadam, S., and B. M. Emerson. 2003. Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. Mol. Cell 11:377-389.
21. Kadonaga, J. 1998. Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines. Cell 92:307-315.
22. Kerr, T., S. Saeki, M. Schneider, K. Schaefer, S. Burdy, T. Redder, B. Shan, D. Russell, and M. Schwaez. 2002. Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis. Dev. Cell 2:713-720.
23. Kim, J., and B. Kemper. 1997. Phenobarbital alters protein binding to the CYP2B1/2 phenobarbital-responsive unit in native chromatin. J. Biol. Chem. 272:29423-29426.
24. Kim, J., L. N. Petz, Y. S. Ziegler, J. R. Wood, S. J. Potthoff, and A. M. Nardulli. 2000. Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells. J. Steroid Biochem. Mol. Biol. 74:157-168.
25. Kim, J., I. Rivera-Rivera, and B. Kemper. 2000. Tissue-chromatin structure of the CYP2B1 phenobarbital-responsive unit and proximal promoter and modulation by phenobarbital. Nucleic Acids Res. 28:1126-1132.
26. Kornberg, R. D., and Y. Lorch. 1999. Twenty five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 98:285-294.
27. Kraus, W. L., and J. Wong. 2002. Nuclear receptor-dependent transcription with chromatin. Is it all about enzymes? Eur. J. Biochem. 269:2275-2283.
28. Lee, H. K., Y. K. Lee, S. H. Park, Y. S. Kim, J. W. Lee, H. B. Kwon, J. Soh, D. D. Moore, and H. S. Choi. 1998. Structure and expression of the orphan nuclear receptor SHP gene. J. Biol. Chem. 273:14398-14402.
29. Lee, Y, H. Dell, D. H. Dowhan, M. Hadzopoulou-Cladaras, and D. D. Moore. 2000. The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression. Mol. Cell. Biol. 20:187-195.
30. Lee, Y., and D. D. Moore. 2002. Dual mechanism for repression of the monomeric orphan receptor liver receptor homologous protein-1 (LRH-1) by the orphan small heterodimer partner (SHP). J. Biol. Chem. 277:2463-2467.
31. Lomvardas, S., and D. Thanos. 2001. Nucleosome sliding via TBP DNA binding in vivo. Cell 106:685-696.
32. Lu, T., M. Makishima, J. Repa, K. Schoonjans, T. A. Kerr, J. Auwerx, and D. J. Mangelsdorf. 2000. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol. Cell 6:507-515.
33. Makishima, M., A. Y. Okamoto, J. J. Repa, H. Tu, M. Learned, A. Luk, M. V. Hull, K. D. Lustig, D. J. Mangelsdorf, and B. Shan. 1999. Identification of a nuclear receptor for bile acids. Science 284:1362-1365.
34. McPherson, C., E. Shim, D. Friedman, and K. Zaret. 1993. An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array. Cell 75:387-397.
35. Min, G., H. Kim, Y. Bae, L. Petz, and J. K. Kemper. 2002. Inhibitory crosstalk between estrogen receptor (ER) and constitutive activated androstane receptor (CAR). J. Biol. Chem. 277:34626-34633.
36. Narlikar, G. J., H. Y. Fan, and R. E. Kingston. 2002. Cooperation between complexes that regulate chromatin structure and transcription. Cell 108:475-487.
37. Nishigori, H., H. Tomura, N. Tonooka, M. Kanamori, S. Yamada, K. Sho, I. Inoue, N. Kikuchi, K. Onigata, I. Kojima, T. Kohama, K. Yamagata, Q. Yang, Y. Matsuzawa, T. Miki, S. Seino, M. Y. Kim, H. S. Choi, Y. K. Lee, D. D. Moore, and J. Takeda. 2001. Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc. Natl. Acad. Sci. USA 98:575-580.
38. Pal, S., R. Yun, A. Datta, L. Lacomis, H. Erdjument-Bromage, J. Kumar, P. Tempst, and S. Sif. 2003. mSin3A/nistone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Mol. Cell. Biol. 23:7475-7487.
39. Peterson, C. L., and J. L. Workman. 2000. Promoter targeting and chromatin remodeling by the SWI/SNF complex. Curr. Opin. Genet. Dev. 10:187-192.
40. Pina, B., U. Bruggemeier, and M. Beato. 1990. Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter. Cell 60:719-731.
41. Reyes, J. C., J. Barra, C. Muchardt, A. Camus, C. Babinet, and M. Yaniv. 1998. Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α). EMBO J. 17:6979-6991.
42. Russell, D. W. 1999. Nuclear orphan receptors control cholesterol catabolism. Cell 97:539-542.
43. Sanyal, S., J. Y. Kim, H. J. Kim, J. Takeda, Y. K. Lee, D. D. Moore, and H. S. Choi. 2002. Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. J. Biol. Chem. 277:1739-1748.
44. Schoonjans, K., J. S. Annicotte, T. Huby, O. A. Botrugno, E. Fayard, Y. Ueda, J. Chapman, and J. Auwerx. 2002. Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I. EMBO Rep. 3:1181-1187.
45. Seol, W., H. Choi, and D. D. Moore. 1996. An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science 272:1336-1339.
46. Seol, W., M. Chung, and D. D. Moore. 1997. Novel receptor interaction and repression domains in the orphan receptor SHP. Mol. Cell. Biol. 17:7126-7131.
47. Shang, Y., X. Hu, J. DiRenzo, M. Lazar, and M. Brown. 2000. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103:843-852.
48. Sif, S., A. J. Saurin, A. N. Imbalzano, and R. E. Kingston. 2001. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. Genes Dev. 15:603-618.
49. Soutoglou, E., and I. Talianidis. 2002. Cordination of PIC assembly and chromatin remodeling during differentiation-induced gene activation. Science 295:1901-1904.
50. Wang, L., Y. Lee, D. Bundman, Y. Han, S. Thevananther, C. Kim, S. Chua, P. Wei, R. Heyman, M. Karin, and D. Moore. 2002. Redundant pathways for negative feedback regulation of bile acid production. Dev. Cell 2:721-731.
51. Workman, J. L., and R. E. Kingston. 1998. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67:545-579.
52. Wu, S., and C. M. Chiang. 2001. Expression and purification of epitope tagged multisubunit protein complexes from mammalian cells, p. 16.22.1-16.22.17. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N. Y.
53. Xue, Y., J. Wong, G. T. Moreno, M. K. Young, J. Cote, and W. Wang. 1998. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell 2:851-861.
54. Yoon, J. C., P. Puigserver, G. Chen, J. Donovan, Z. Wu, J. Rhee, G. Adelmant, J. Stafford, C. R. Kahn, D. K. Granner, C. B. Newgard, and B. M. Spiegelman. 2001. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413:131-138.
55. 1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 101:79-89.
56. Zhang, M., and J. Y. Chiang. 2001. Transcriptional regulation of the human sterol 12α-hydroxylase gene (CYP8B1): roles of hepatocyte nuclear factor 4α in mediating bile acid repression. J. Biol. Chem. 276:41690-41699.