Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of α-helix-based peptide amphiphiles

Biomaterials

Volumn 52, Issue 1, 2015, Pages 517-530

  Ma, Zhi ^a   Wei, Dandan ^a   Yan, Ping ^a   Zhu, Xin ^a   Shan, Anshan ^a   Bi, Zhongpeng ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

Antimicrobial peptides; Bactericidal mechanism; Endotoxin; Hybridization; Selectivity; Helix

Indexed keywords

ANTIMICROBIAL AGENTS; BLOOD; CATALYST SELECTIVITY; CELLS; CYTOLOGY; FLUORESCENCE SPECTROSCOPY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; MICROORGANISMS; SCANNING ELECTRON MICROSCOPY;

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; BACTERICIDAL MECHANISMS; ENDOTOXIN; ENDOTOXIN NEUTRALIZATION; HYBRIDIZATION; PHYSIOLOGICAL CONCENTRATIONS; THERAPEUTIC POTENTIALS;

PEPTIDES;

ENDOTOXIN; FOWLICIDIN 2; INORGANIC SALT; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEGRIN 3; PRW4 PEPTIDE; TRITRPTICIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; LIPOPOLYSACCHARIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BACTERIAL CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; ERYTHROCYTE; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HUMAN; HYBRID; IN VITRO STUDY; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; CELL MEMBRANE PERMEABILITY; CHEMISTRY; CIRCULAR DICHROISM; CYTOPLASM; DRUG EFFECTS; HEMOLYSIS; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PERMEABILITY; PROTEIN SECONDARY STRUCTURE; SEPSIS;

BACTERIA (MICROORGANISMS);

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; CYTOPLASM; ENDOTOXINS; ERYTHROCYTES; HEMOLYSIS; HUMANS; LIPOPOLYSACCHARIDES; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PERMEABILITY; PROTEIN STRUCTURE, SECONDARY; SEPSIS;

EID: 84932624204     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.02.063     Document Type: Article

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