Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates

European Journal of Medicinal Chemistry

Volumn 71, Issue , 2014, Pages 31-35

  Faccone, Diego ^a   Veliz, Omar ^a   Corso, Alejandra ^a   Noguera, Martin ^c   Martínez, Melina ^b   Payes, Cristian ^b,c   Semorile, Liliana ^b   Maffía, Paulo Cesar ^b,c  

^a INSTITUTO NACIONAL DE ENFERMEDADES INFECCIOSAS   (Argentina)

^b UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Antimicrobial; Cationic; Peptides; Resistance

Indexed keywords

ANTIMICROBIAL CATIONIC PEPTIDE; OMIGANAN; CATION; CATIONIC ALPHA HELICAL PEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ERYTHROCYTE; HUMAN; HUMAN CELL; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; PHYSICAL CHEMISTRY; ALPHA HELIX; BACTERIUM ISOLATION; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; HEMOLYSIS; KLEBSIELLA PNEUMONIAE; NONHUMAN; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS COHNII; STAPHYLOCOCCUS WARNERI; STRUCTURE ANALYSIS; WILD TYPE;

ANTIMICROBIAL; CATIONIC; PEPTIDES; RESISTANCE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; BACTERIAL INFECTIONS; CIRCULAR DICHROISM; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA;

EID: 84887635502     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.10.065     Document Type: Article

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