Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation

Nature Materials

Volumn 14, Issue 7, 2015, Pages 696-701

  Schmidt, Nathan W ^a   Jin, Fan ^a,b   Lande, Roberto ^c,d   Curk, Tine ^e   Xian, Wujing ^a   Lee, Calvin ^a   Frasca, Loredana ^c,d   Frenkel, Daan ^e   Dobnikar, Jure ^e,f,g   Gilliet, Michel ^c   Wong, Gerard C L ^a  

^a Engineering IV   (United States)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f JO EF STEFAN INSTITUTE   (Slovenia)

^g BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; CHEMICAL ACTIVATION; CRYSTALLINE MATERIALS; DNA; IMMUNE SYSTEM; INTERFERONS; MICROORGANISMS; PEPTIDES; POLYPEPTIDES; X RAY SCATTERING;

ANTIMICROBIAL PEPTIDE; AUTOIMMUNE DISEASE; CATIONIC MOLECULES; DOUBLE-STRANDED DNA (DS-DNA); LIQUID CRYSTALLINE; PLASMACYTOID DENDRITIC CELLS; TOLL-LIKE RECEPTORS; TYPE I INTERFERONS;

BIOINFORMATICS;

ALPHA INTERFERON; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; DNA; INTERFERON; OLIGONUCLEOTIDE; TLR9 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 9;

CHEMISTRY; COMPUTER SIMULATION; CPG ISLAND; CRYSTALLIZATION; CYTOLOGY; DENDRITIC CELL; ENDOSOME; HUMAN; LIQUID CRYSTAL; METABOLISM; MONTE CARLO METHOD; RADIATION SCATTERING; STATIC ELECTRICITY; X RAY;

ANTIMICROBIAL CATIONIC PEPTIDES; COMPUTER SIMULATION; CPG ISLANDS; CRYSTALLIZATION; DENDRITIC CELLS; DNA; ENDOSOMES; HUMANS; INTERFERON TYPE I; INTERFERON-ALPHA; LIQUID CRYSTALS; MONTE CARLO METHOD; OLIGONUCLEOTIDES; SCATTERING, RADIATION; STATIC ELECTRICITY; TOLL-LIKE RECEPTOR 9; X-RAYS;

EID: 84932192810     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat4298     Document Type: Article

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