메뉴 건너뛰기




Volumn 122, Issue 4, 2015, Pages 908-920

Spinal Peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ANALGESIC AGENT; IRON; IRON CHELATING AGENT; ISONIAZID DERIVATIVE; MANGANESE SUPEROXIDE DISMUTASE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PEROXYNITRITE; REMIFENTANIL; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; CATION TRANSPORT PROTEIN; IRON REGULATORY FACTOR; PEROXYNITROUS ACID; PIPERIDINE DERIVATIVE; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2;

EID: 84932083350     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000562     Document Type: Article
Times cited : (39)

References (64)
  • 1
    • 33645509700 scopus 로고    scopus 로고
    • Opioid-induced hyperalgesia: A qualitative systematic review
    • Angst MS, Clark JD: Opioid-induced hyperalgesia: A qualitative systematic review. Anesthesio logy 2006; 104:570-87
    • (2006) Anesthesio Logy , vol.104 , pp. 570-587
    • Angst, M.S.1    Clark, J.D.2
  • 2
    • 0142196082 scopus 로고    scopus 로고
    • Shortterm infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal
    • Angst MS, Koppert W, Pahl I, Clark DJ, Schmelz M: Shortterm infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal. Pain 2003; 106:49-57
    • (2003) Pain , vol.106 , pp. 49-57
    • Angst, M.S.1    Koppert, W.2    Pahl, I.3    Clark, D.J.4    Schmelz, M.5
  • 3
    • 33645523617 scopus 로고    scopus 로고
    • Opioid-induced hyperalgesia in a murine model of postoperative pain: Role of nitric oxide generated from the inducible nitric oxide synthase
    • Célérier E, González JR, Maldonado R, Cabañero D, Puig MM: Opioid-induced hyperalgesia in a murine model of postoperative pain: Role of nitric oxide generated from the inducible nitric oxide synthase. Anesthesio logy 2006; 104:546-55
    • (2006) Anesthesio Logy , vol.104 , pp. 546-555
    • Célérier, E.1    González, J.R.2    Maldonado, R.3    Cabañero, D.4    Puig, M.M.5
  • 5
    • 0142165206 scopus 로고    scopus 로고
    • Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans
    • Koppert W, Angst M, Alsheimer M, Sittl R, Albrecht S, Schüttler J, Schmelz M: Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans. Pain 2003; 106:91-9
    • (2003) Pain , vol.106 , pp. 91-99
    • Koppert, W.1    Angst, M.2    Alsheimer, M.3    Sittl, R.4    Albrecht, S.5    Schüttler, J.6    Schmelz, M.7
  • 7
    • 84904654274 scopus 로고    scopus 로고
    • Intraoperative use of remifentanil and opioid induced hyperalgesia/acute opioid tolerance: Systematic review
    • Kim SH, Stoicea N, Soghomonyan S, Bergese SD: Intraoperative use of remifentanil and opioid induced hyperalgesia/acute opioid tolerance: Systematic review. Front Pharmacol 2014; 5:108
    • (2014) Front Pharmacol , vol.5 , pp. 108
    • Kim, S.H.1    Stoicea, N.2    Soghomonyan, S.3    Bergese, S.D.4
  • 8
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87:1620-4
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 10
    • 84860247101 scopus 로고    scopus 로고
    • Reactive nitroxidative species and nociceptive processing: Determining the roles for nitric oxide, superoxide, and peroxynitrite in pain
    • Little JW, Doyle T, Salvemini D: Reactive nitroxidative species and nociceptive processing: Determining the roles for nitric oxide, superoxide, and peroxynitrite in pain. Amino Acids 2012; 42:75-94
    • (2012) Amino Acids , vol.42 , pp. 75-94
    • Little, J.W.1    Doyle, T.2    Salvemini, D.3
  • 13
    • 79851510995 scopus 로고    scopus 로고
    • Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats
    • Doyle T, Finley A, Chen Z, Salvemini D: Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats. Pain 2011; 152:643-8
    • (2011) Pain , vol.152 , pp. 643-648
    • Doyle, T.1    Finley, A.2    Chen, Z.3    Salvemini, D.4
  • 14
    • 84886259398 scopus 로고    scopus 로고
    • Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase
    • Janes K, Doyle T, Bryant L, Esposito E, Cuzzocrea S, Ryerse J, Bennett GJ, Salvemini D: Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase. Pain 2013; 154:2432-40
    • (2013) Pain , vol.154 , pp. 2432-2440
    • Janes, K.1    Doyle, T.2    Bryant, L.3    Esposito, E.4    Cuzzocrea, S.5    Ryerse, J.6    Bennett, G.J.7    Salvemini, D.8
  • 15
    • 4344647033 scopus 로고    scopus 로고
    • Superoxide-mediated nitration of spinal manganese superoxide dismutase: A novel pathway in N-methyl-D-aspartate-mediated hyperalgesia
    • Muscoli C, Mollace V, Wheatley J, Masini E, Ndengele M, Wang ZQ, Salvemini D: Superoxide-mediated nitration of spinal manganese superoxide dismutase: A novel pathway in N-methyl-D-aspartate-mediated hyperalgesia. Pain 2004; 111:96-103
    • (2004) Pain , vol.111 , pp. 96-103
    • Muscoli, C.1    Mollace, V.2    Wheatley, J.3    Masini, E.4    Ndengele, M.5    Wang, Z.Q.6    Salvemini, D.7
  • 17
    • 84878794004 scopus 로고    scopus 로고
    • Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance
    • Little JW, Cuzzocrea S, Bryant L, Esposito E, Doyle T, Rausaria S, Neumann WL, Salvemini D: Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance. Pain 2013; 154:978-86
    • (2013) Pain , vol.154 , pp. 978-986
    • Little, J.W.1    Cuzzocrea, S.2    Bryant, L.3    Esposito, E.4    Doyle, T.5    Rausaria, S.6    Neumann, W.L.7    Salvemini, D.8
  • 18
    • 77956365461 scopus 로고    scopus 로고
    • Recent advances in hydrogen research as a therapeutic medical gas
    • Huang CS, Kawamura T, Toyoda Y, Nakao A: Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res 2010; 44:971-82
    • (2010) Free Radic Res , vol.44 , pp. 971-982
    • Huang, C.S.1    Kawamura, T.2    Toyoda, Y.3    Nakao, A.4
  • 20
    • 84863648677 scopus 로고    scopus 로고
    • Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide
    • Hanaoka T, Kamimura N, Yokota T, Takai S, Ohta S: Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide. Med Gas Res 2011; 1:18
    • (2011) Med Gas Res , vol.1 , pp. 18
    • Hanaoka, T.1    Kamimura, N.2    Yokota, T.3    Takai, S.4    Ohta, S.5
  • 22
    • 77950596200 scopus 로고    scopus 로고
    • Hydrogenrich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress
    • Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ: Hydrogenrich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Res 2010; 1328:152-61
    • (2010) Brain Res , vol.1328 , pp. 152-161
    • Li, J.1    Wang, C.2    Zhang, J.H.3    Cai, J.M.4    Cao, Y.P.5    Sun, X.J.6
  • 23
    • 84862776559 scopus 로고    scopus 로고
    • Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats
    • Zhan Y, Chen C, Suzuki H, Hu Q, Zhi X, Zhang JH: Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Crit Care Med 2012; 40:1291-6
    • (2012) Crit Care Med , vol.40 , pp. 1291-1296
    • Zhan, Y.1    Chen, C.2    Suzuki, H.3    Hu, Q.4    Zhi, X.5    Zhang, J.H.6
  • 24
    • 29144450958 scopus 로고    scopus 로고
    • Divalent metal transporter 1
    • Mims MP, Prchal JT: Divalent metal transporter 1. Hematology 2005; 10:339-45
    • (2005) Hematology , vol.10 , pp. 339-345
    • Mims, M.P.1    Prchal, J.T.2
  • 25
    • 0037126002 scopus 로고    scopus 로고
    • Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
    • Hubert N, Hentze MW: Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function. Proc Natl Acad Sci USA 2002; 99:12345-50
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12345-12350
    • Hubert, N.1    Hentze, M.W.2
  • 26
    • 84887212418 scopus 로고    scopus 로고
    • L-DOPA neurotoxicity is mediated by up-regulation of DMT1-IRE expression
    • Du F, Qian ZM, Zhu L, Wu XM, Yung WH, Tsim TY, Ke Y: L-DOPA neurotoxicity is mediated by up-regulation of DMT1-IRE expression. PLoS One 2009; 4:e4593
    • (2009) PLoS One , vol.4 , pp. e4593
    • Du, F.1    Qian, Z.M.2    Zhu, L.3    Wu, X.M.4    Yung, W.H.5    Tsim, T.Y.6    Ke, Y.7
  • 27
    • 0038491413 scopus 로고    scopus 로고
    • Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor
    • Touret N, Furuya W, Forbes J, Gros P, Grinstein S: Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem 2003; 278:25548-57
    • (2003) J Biol Chem , vol.278 , pp. 25548-25557
    • Touret, N.1    Furuya, W.2    Forbes, J.3    Gros, P.4    Grinstein, S.5
  • 28
    • 67650474704 scopus 로고    scopus 로고
    • Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells
    • Zhang S, Wang J, Song N, Xie J, Jiang H: Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells. Neurobiol Aging 2009; 30:1466-76
    • (2009) Neurobiol Aging , vol.30 , pp. 1466-1476
    • Zhang, S.1    Wang, J.2    Song, N.3    Xie, J.4    Jiang, H.5
  • 33
    • 67649739079 scopus 로고    scopus 로고
    • Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis
    • Altamura S, Muckenthaler MU: Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis. J Alzheimers Dis 2009; 16:879-95
    • (2009) J Alzheimers Dis , vol.16 , pp. 879-895
    • Altamura, S.1    Muckenthaler, M.U.2
  • 34
    • 58849116869 scopus 로고    scopus 로고
    • Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis
    • Jeong SY, Rathore KI, Schulz K, Ponka P, Arosio P, David S: Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2009; 29:610-9
    • (2009) J Neurosci , vol.29 , pp. 610-619
    • Jeong, S.Y.1    Rathore, K.I.2    Schulz, K.3    Ponka, P.4    Arosio, P.5    David, S.6
  • 35
    • 84872846956 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 contributes to remifentanil-induced postoperative hyperalgesia via regulating N-methyl-D-aspartate receptor trafficking
    • Yuan Y, Wang JY, Yuan F, Xie KL, Yu YH, Wang GL : Glycogen synthase kinase-3 contributes to remifentanil-induced postoperative hyperalgesia via regulating N-methyl-D-aspartate receptor trafficking. Anesth Analg 2013; 116:473-81
    • (2013) Anesth Analg , vol.116 , pp. 473-481
    • Yuan, Y.1    Wang, J.Y.2    Yuan, F.3    Xie, K.L.4    Yu, Y.H.5    Wang, G.L.6
  • 36
    • 84885775906 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 prevents remifentanil-induced hyperalgesia via regulating the expression and function of spinal N-methyl-D-aspartate receptors in vivo and vitro
    • Li Y, Wang H, Xie K, Wang C, Yang Z, Yu Y, Wang G: Inhibition of glycogen synthase kinase-3 prevents remifentanil-induced hyperalgesia via regulating the expression and function of spinal N-methyl-D-aspartate receptors in vivo and vitro. PLoS One 2013; 8:e77790
    • (2013) PLoS One , vol.8 , pp. e77790
    • Li, Y.1    Wang, H.2    Xie, K.3    Wang, C.4    Yang, Z.5    Yu, Y.6    Wang, G.7
  • 40
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • Smith MA, Harris PL, Sayre LM, Perry G: Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA 1997; 94:9866-8
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 41
    • 79954603488 scopus 로고    scopus 로고
    • Effects of formaldehyde inhalation on zinc, copper and iron concentrations in liver and kidney of male rats
    • Ozen OA, Kus I, Bakirdere S, Sarsilmaz M, Yaman M: Effects of formaldehyde inhalation on zinc, copper and iron concentrations in liver and kidney of male rats. Biol Trace Elem Res 2011; 140:177-85
    • (2011) Biol Trace Elem Res , vol.140 , pp. 177-185
    • Ozen, O.A.1    Kus, I.2    Bakirdere, S.3    Sarsilmaz, M.4    Yaman, M.5
  • 42
    • 0032147208 scopus 로고    scopus 로고
    • Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species
    • Ischiropoulos H: Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys 1998; 356:1-11
    • (1998) Arch Biochem Biophys , vol.356 , pp. 1-11
    • Ischiropoulos, H.1
  • 43
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
    • Szabó C, Ischiropoulos H, Radi R: Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 2007; 6:662-80
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 662-680
    • Szabó, C.1    Ischiropoulos, H.2    Radi, R.3
  • 45
    • 0029942939 scopus 로고    scopus 로고
    • Characterization of a rat model of incisional pain
    • Brennan TJ, Vandermeulen EP, Gebhart GF: Characterization of a rat model of incisional pain. Pain 1996; 64:493-501
    • (1996) Pain , vol.64 , pp. 493-501
    • Brennan, T.J.1    Vandermeulen, E.P.2    Gebhart, G.F.3
  • 46
    • 84857370967 scopus 로고    scopus 로고
    • Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization
    • Barrière DA, Rieusset J, Chanteranne D, Busserolles J, Chauvin MA, Chapuis L, Salles J, Dubray C, Morio B: Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization. Pain 2012; 153:553-61
    • (2012) Pain , vol.153 , pp. 553-561
    • Barrière, D.A.1    Rieusset, J.2    Chanteranne, D.3    Busserolles, J.4    Chauvin, M.A.5    Chapuis, L.6    Salles, J.7    Dubray, C.8    Morio, B.9
  • 47
    • 79960451991 scopus 로고    scopus 로고
    • Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia
    • Chu C, Levine E, Gear RW, Bogen O, Levine JD: Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia. Pain 2011; 152:1832-7
    • (2011) Pain , vol.152 , pp. 1832-1837
    • Chu, C.1    Levine, E.2    Gear, R.W.3    Bogen, O.4    Levine, J.D.5
  • 48
    • 3543008400 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiratory complex i by nitric oxide, peroxynitrite and S-nitrosothiols
    • Brown GC, Borutaite V: Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim Biophys Acta 2004; 1658:44-9
    • (2004) Biochim Biophys Acta , vol.1658 , pp. 44-49
    • Brown, G.C.1    Borutaite, V.2
  • 51
    • 0141458065 scopus 로고    scopus 로고
    • The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review
    • Petrenko AB, Yamakura T, Baba H, Shimoji K: The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review. Anesth Analg 2003; 97:1108-16
    • (2003) Anesth Analg , vol.97 , pp. 1108-1116
    • Petrenko, A.B.1    Yamakura, T.2    Baba, H.3    Shimoji, K.4
  • 52
    • 63849103058 scopus 로고    scopus 로고
    • Role of peroxynitrite in the redox regulation of cell signal transduction pathways
    • Liaudet L, Vassalli G, Pacher P: Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci (Landmark Ed) 2009; 14:4809-14
    • (2009) Front Biosci (Landmark Ed) , vol.14 , pp. 4809-4814
    • Liaudet, L.1    Vassalli, G.2    Pacher, P.3
  • 53
    • 32944457363 scopus 로고    scopus 로고
    • Nitric oxide transcriptionally downregulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB
    • Paradkar PN, Roth JA: Nitric oxide transcriptionally downregulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB. J Neurochem 2006; 96:1768-77
    • (2006) J Neurochem , vol.96 , pp. 1768-1777
    • Paradkar, P.N.1    Roth, J.A.2
  • 54
    • 32944477219 scopus 로고    scopus 로고
    • Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid
    • Paradkar PN, Roth JA: Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid. Biochem J 2006; 394(pt 1):173-83
    • (2006) Biochem J , vol.394 , pp. 173-183
    • Paradkar, P.N.1    Roth, J.A.2
  • 57
    • 1842608845 scopus 로고    scopus 로고
    • Iron metabolism and the IRE/IRP regulatory system: An update
    • Pantopoulos K: Iron metabolism and the IRE/IRP regulatory system: An update. Ann N Y Acad Sci 2004; 1012:1-13
    • (2004) Ann N y Acad Sci , vol.1012 , pp. 1-13
    • Pantopoulos, K.1
  • 58
    • 0025186342 scopus 로고
    • High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: Reversal by intensified chelation
    • Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Ward SE, Agnew JE, Hilson AJ: High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: Reversal by intensified chelation. Acta Haematol 1990; 84:113-7
    • (1990) Acta Haematol , vol.84 , pp. 113-117
    • Aldouri, M.A.1    Wonke, B.2    Hoffbrand, A.V.3    Flynn, D.M.4    Ward, S.E.5    Agnew, J.E.6    Hilson, A.J.7
  • 59
    • 0036569986 scopus 로고    scopus 로고
    • Molecular bases of cellular iron toxicity
    • Eaton JW, Qian M: Molecular bases of cellular iron toxicity. Free Radic Biol Med 2002; 32:833-40
    • (2002) Free Radic Biol Med , vol.32 , pp. 833-840
    • Eaton, J.W.1    Qian, M.2
  • 60
    • 59249086968 scopus 로고    scopus 로고
    • Current status in iron chelation in hemoglobinopathies
    • Cappellini MD, Piga A: Current status in iron chelation in hemoglobinopathies. Curr Mol Med 2008; 8:663-74
    • (2008) Curr Mol Med , vol.8 , pp. 663-674
    • Cappellini, M.D.1    Piga, A.2
  • 62
    • 77953903866 scopus 로고    scopus 로고
    • Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release
    • Xie K, Yu Y, Pei Y, Hou L, Chen S, Xiong L, Wang G: Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. Shock 2010; 34:90-7
    • (2010) Shock , vol.34 , pp. 90-97
    • Xie, K.1    Yu, Y.2    Pei, Y.3    Hou, L.4    Chen, S.5    Xiong, L.6    Wang, G.7
  • 63
    • 84903182527 scopus 로고    scopus 로고
    • Hydrogen-rich saline controls remifentanil-induced hypernociception and NMDA receptor NR1 subunit membrane trafficking through GSK-3 in the DRG in rats
    • Zhang L, Shu R, Wang C, Wang H, Li N, Wang G: Hydrogen-rich saline controls remifentanil-induced hypernociception and NMDA receptor NR1 subunit membrane trafficking through GSK-3 in the DRG in rats. Brain Res Bull 2014; 106:47-55
    • (2014) Brain Res Bull , vol.106 , pp. 47-55
    • Zhang, L.1    Shu, R.2    Wang, C.3    Wang, H.4    Li, N.5    Wang, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.