Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway

Journal of Neuroscience

Volumn 32, Issue 32, 2012, Pages 10797-10808

  Little, Joshua W ^a   Chen, Zhoumou ^a   Doyle, Timothy ^a   Porreca, Frank ^b   Ghaffari, Mahsa ^c   Bryant, Leesa ^a   Neumann, William L ^c   Salvemini, Daniela ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; DELTA OPIATE RECEPTOR; ENKEPHALIN; GLIAL FIBRILLARY ACIDIC PROTEIN; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NEURON SPECIFIC NUCLEAR PROTEIN; OPIATE; OPIATE RECEPTOR; PEROXYNITRITE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HYPERALGESIA; IMMUNOFLUORESCENCE TEST; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; CARRAGEENAN; CELL LINE, TRANSFORMED; CHROMATOGRAPHY, LIQUID; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCHEMICAL TECHNIQUES; ENKEPHALIN, METHIONINE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MEDULLA OBLONGATA; METALLOPORPHYRINS; MICROINJECTIONS; NEUROGLIA; NEURONS; OPIOID PEPTIDES; PAIN; PAIN MEASUREMENT; PEROXYNITROUS ACID; PHOSPHOPYRUVATE HYDRATASE; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84864844175     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6345-11.2012     Document Type: Article

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