Wogonin Induced Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Human Malignant Neuroblastoma Cells Via IRE1α-Dependent Pathway

Journal of Molecular Neuroscience

Volumn 56, Issue 3, 2015, Pages 652-662

  Ge, Wenliang ^a   Yin, Qiyou ^a   Xian, Hua ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; IRE1 ; Malignant neuroblastoma; Mitochondrial dysfunction; Wogonin

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 12; CASPASE 3; CASPASE 4; CASPASE 8; CASPASE 9; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN IRE1; PROTEIN IRE1 ALPHA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; WOGONIN; ANTINEOPLASTIC AGENT; ERN1 PROTEIN, HUMAN; FLAVANONE DERIVATIVE; MAP3K5 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL VIABILITY; DOSE RESPONSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; MITOCHONDRION; NEUROBLASTOMA; NEUROBLASTOMA CELL LINE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; DRUG EFFECTS; GENETICS; METABOLISM; TUMOR CELL LINE;

SCUTELLARIA BAICALENSIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FLAVANONES; HUMANS; MAP KINASE KINASE 4; MAP KINASE KINASE KINASE 5; MITOCHONDRIA; NEUROBLASTOMA; PROTEIN-SERINE-THREONINE KINASES; TNF RECEPTOR-ASSOCIATED FACTOR 2;

EID: 84931564533     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0530-9     Document Type: Article

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