Identification and analysis of novel R308K mutation in glucokinase of type 2 diabetic patient and its kinetic correlation

Biotechnology and Applied Biochemistry

Volumn 61, Issue 5, 2014, Pages 572-581

  Yellapu, Nanda Kumar ^a   Valasani, Koteswara Rao ^b   Pasupuleti, Santhosh Kumar ^c   Gopal, Sowjenya ^c   Potukuchi Venkata Gurunadha Krishna, Sarma ^c   Matcha, Bhaskar ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b UNIVERSITY OF KANSAS   (United States)

^c SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

enzyme activity; glucokinase; MODY2; molecular docking; molecular dynamics

Indexed keywords

ENZYMES; GENES; GLUCOSE; KINETICS; MOLECULAR DYNAMICS;

AUTOSOMAL DOMINANTS; GLUCOKINASE; GLUCOSE 6 PHOSPHATES; GLUCOSE HOMEOSTASIS; HUMAN LIVER TISSUES; MATURITY-ONSET DIABETES OF THE YOUNG; MODY2; MOLECULAR DOCKING;

ENZYME ACTIVITY;

AMMONIUM SULFATE; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATE; HYDROGEN; HYDROXYL GROUP;

AGAR GEL ELECTROPHORESIS; AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ELUTION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME PURIFICATION; EXON; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; HYDROGEN BOND; LIVER BIOPSY; LIVER HOMOGENATE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIMULATION; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; LIVER; METABOLISM; MOLECULAR GENETICS; MUTATION; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; DIABETES MELLITUS, TYPE 2; GLUCOKINASE; GLUCOSE; HUMANS; KINETICS; LIVER; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ALIGNMENT;

EID: 84931385138     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1209     Document Type: Article

References (52)

1. Matschinsky, F. M., (1996) Diabetes 45, 223-241.
2. Iynedjian, P. B., Pilot, P. R., Nouspikel, T., Milburn, J. L., Quaade, C., Hughes, S., Ucla, C., and, Newgard, C. B., (1989) Proc. Natl. Acad. Sci. USA 86, 7838-7842.
3. Jetton, T. L., Shiota, M., Knobel, S. M., Piston, D. W., Cherrington, A. D., and, Magnuson, M. A., (2001) Int. J. Exp. Diabetes Res. 2, 173-186.
4. Shiota, C., Coffey, J., Grimsby, J., Grippo, J. F., and, Magnuson, M. A., (1999) J. Biol. Chem. 274, 37125-37130.
5. Cárdenas, M. L., Cornish, B. A., and, Ureta, T., (1998) Biochim. Biophys. Acta 1401, 242-264.
6. Matschinsky, F. M., Magnuson, M. A., Zelent, D., Jetton, T. L., Doliba, N., Han, Y., Taub, R., and, Grimsby, J., (2006) Diabetes 55, 1-12.
7. Lin, S. X., and, Neet, K. E., (1990) J. Biol. Chem. 265, 9670-9675.
8. Froguel, P., Zouali, H., Vionnet, N., Velho, G., Vaxillaire, M., Sun, F., Lesage, S., Stoffel, M., Takeda, J., Passa, P., Permutt, M. A., Beckmann, J. S., Bell, G. I., and, Cohen, D., (1993) N. Engl. J. Med. 328, 697-702.
9. Hager, J., Blanche, H., Sun, F., Vaxillaire, N. V., Poller, W., Cohen, D., Czernichow, P., Velho, G., Robert, J. J., Cohen, N., and, Froguel, P., (1994) Diabetes 43, 730-733.
10. Stoffel, M., Froguel, P., Takeda, J., Zouali, H., Vionnet, N., Nishi, S., Weber, I. T., Harrison, R. W., Pilkis, S. J., and, Lesage, S., (1992) Proc. Natl. Acad. Sci. USA 89, 7698-7702.
11. Sun, F., Knebelmann, B., Pueyo, M. E., Zouali, H., Lesage, S., Vaxillaire, M., Passa, P., Cohen, D., Velho, G., and, Antignac, C., (1993) J. Clin. Invest. 92, 1174-1180.
12. Vionnet, N., Stoffel, M., Takeda, J., Yasuda, K., Bell, G. I., Zouali, H., Lesage, S., Velho, G., Iris, F., Passa, P., Froguel, P. H., and, Cohen, D., (1992) Nature 356, 721-722.
13. Zouali, H., Vaxillaire, M., Lesage, S., Sun, F., Velho, G., Vionnet, N., Chiu, K., Passa, P., Permutt, A., Demenais, F., Cohen, D., Beckmann, J., and, Froguel, P., (1993) Diabetes 42, 1238-1245.
14. Bell, G. I., Pilkis, S. J., Weber, I. T., and, Polonsky, K. S., (1996) Annu. Rev. Physiol. 58, 171-186.
15. Velho, G., Blanche, H., Vaxillaire, M., Bellanne-Chantelot, C., Pardini, V. C., Timsit, J., Passa, P., Deschamps, I., Robert, J. J., Weber, I. T., Marotta, D., Pilkis, S. J., Lipkind, G. M., Bell, G. I., and, Froguel, P., (1997) Diabetologia 40, 217-224.
16. Glaser, B., Kesavan, P., Heyman, M., Davis, E., Cuesta, A., Buchs, A., Stanley, C. A., Thornton, P. S., Permutt, M. A., Matschinsky, F. M., and, Herold, K. C., (1998) N. Engl. J. Med. 338, 226-230.
17. Kesavan, P., Wang, L., Davis, E., Cuesta, A., Sweet, I., Niswender, K., Magnuson, M. A., and, Matschinsky, F. M., (1997) Biochem. J. 322, 57-63.
18. Gidh-Jain, M., Takeda, J., Xu, L. Z., Lange, A. J., Vionnet, N., Stoffel, M., Froguel, P., Velho, G., Sun, F., and, Cohen, D., (1993) Proc. Natl. Acad. Sci. USA 90, 1932-1936.
19. Burke, C. V., Buettger, C. W., Davis, E. A., McClane, S. J., Matschinsky, F. M., and, Raper, S. E., (1999) Biochem. J. 342, 345-352.
20. Gloyn, A. L., Odili, S., Zelent, D., Buettger, C., Castleden, H. A., Steele, A. M., Stride, A., Shiota, C., Magnuson, M. A., Lorini, R., Annunzio, G., Stanley, C. A., Kwagh, J., Schaftingeni, E. V., Cunha, M. V. D., Barbetti, F., Dunten, P., Han, Y., Grimsby, J., Taub, R., Ellard, S., Hattersley, A. T., and, Matschinsky, F. M., (2005) J. Biol. Chem. 280, 14105-14113.
21. Berman, H. M., Westbrook, J., Feng, Z., Gilliland, G., Bhat, T. N., Weissig, H., Shindyalov, I. N., and, Bourne, P. E., (2000) Nucleic Acids Res. 28, 235-242.
22. Nelson, A. C., Huang, W., and, Moody, D. E., (2001) Drug Metab. Dispos. 29, 319-325.
23. Clore, J. N., Stillman, J., and, Sugerman, H., (2000) Diabetes 49, 969-974.
24. Cardenas, M. L., Rabajille, E., and, Niemeyer, H., (1984) Eur. J. Biochem. 145, 163-171.
25. Belfiore, F., Romeo, F., Iannello, S., and, Salamone, C., (1989) Biochem. Med. Metab. Biol. 41, 77-80.
26. Mahalingam, B., Cuesta-Munoz, A., Davis, E. A., Matschinsky, F. M., Harrison, R. W., and, Weber, I. T., (1999) Diabetes 48, 1698-1705.
27. Kamata, K., Mitsuya, M., Nishimura, T., Eiki, J., and, Nagata, Y., (2004) Structure 12, 429-438.
28. Rozen, S., and, Skaletsky, H., (2000) Methods Mol. Biol. 132, 365-386.
29. Bairoch, A., and, Boeckmann, B., (1992) Nucleic Acids Res. 20, 2019-2022.
30. Thomas, A. H., (1996) J. Comput. Chem. 17, 490-519.
31. Zhang, J., Li, C., Chen, K., Zhu, W., Shen, X., and, Jiang, H., (2006) Proc. Natl. Acad. Sci. USA 103, 13368-13373.
32. Jess, B. S., and, Brian, B. L., (2000) J. Chem. Phys. 112, 3474.
33. Udatha, D. B., Sugaya, N., Olsson, L., and, Panagiotou, G., (2012) Sci. Rep. 2, 323.
34. Brooijmans, N., and, Kuntz, I. D., (2003) Annu. Rev. Biophys. Biomol. Struct. 32, 335-373.
35. Rarey, M., Wefing, S., and, Lengauer, T., (1996) J. Comput. Aided Mol. Des. 10, 41-54.
36. Tame, J. R., (1999) J. Comput. Aided Mol. Des. 13, 99-108.
37. Kumar, Y. N., Kumar, P. S., Sowjenya, G., Rao, V. K., Yeswanth, S., Prasad, U. V., Pradeepkiran, J. A., Sarma, P., and, Bhaskar, M., (2012) Bioinformation 8, 543-547.
38. Valasani, K. R., Hu, G., Chaney, M. O., and, Yan, S. S., (2012) Chem. Biol. Drug. Des. 81, 238-249.
39. Belfiore, F., Romeo, F., Napoli, E., and, Lo Vecchio, L., (1974) Diabetes 23, 293-301.
40. Barzilai, N., and, Rossetti, L., (1993) J. Biol. Chem. 268, 25019-25025.
41. Walsh, R., Martin, E., and, Darvesh, S., (2010) Biochim. Biophys. Acta 1800, 1-5.
42. Iynedjian, P. B., Marie, S., Gjinovci, A., Genin, B., Deng, S. P., Buhler, L., Morel, P., and, Mentha, G., (1995) J. Clin. Invest. 95, 1966-1973.
43. Ferre, T., Pujol, A., Riu, E., Bosch, F., and, Valera, A., (1996) Proc. Natl. Acad. Sci. USA 93, 7225-7230.
44. Miller, S. P., Anand, G. R., Karschnia, E. J., Bell, G. I., LaPorte, D. C., and, Lange, A. J., (1999) Diabetes 48, 1645-1651.
45. Davis, E. A., Cuesta-Munoz, A., Raoul, M., Buettger, C., Sweet, I., Moates, M., Magnuson, M. A., and, Matschinsky, F. M., (1999) Diabetologia 42, 1175-1186.
46. Estalella, I., Garcia-Gimeno, M. A., Marina, A., Castano, L., and, Sanz, P., (2008) J. Hum. Genet. 53, 460-466.
47. Zhang, J., Li, C., Shi, T., Chen, K., Shen, X., and, Jiang, H., (2009) PloS One 4, e6304.
48. Petit, P., Antoine, M., Ferry, G., Boutin, J. A., Lagarde, A., Gluais, L., Vincentelli, R., and, Vuillard, L., (2011) Acta Crystallogr. D. Biol. Crystallogr. 67, 929-935.
49. Kamata, K., Mitsuya, M,., Nishimura, T., Eiki, J., and, Nagata, Y., (2004) Structure 12, 429-438.
50. Nanda Kumar, Y,., Kalpana, K., Koteswara Rao, V., Sarma, P. V. G. K., and, Bhaskar, M., (2013) Biotechnol. Res. Int. 2013, Article ID 264793, doi: 10.1155/2013/264793.
51. Heredia, V. V., Carlson, T. J., Garcia, E., and, Sun, S., (2006) J. Biol. Chem. 281, 40201-40207.
52. Matschinsky, F. M., (2009) Nat. Rev. Drug. Discov. 8, 399-416.