Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase

Journal of Biological Chemistry

Volumn 274, Issue 52, 1999, Pages 37125-37130

  Shiota, Chiyo ^a   Coffey, Jack ^b   Grimsby, Joseph ^b   Grippo, Joseph F ^b   Magnuson, Mark A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Hoffman La Roche Department of Metabolic Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLUCOKINASE; HYBRID PROTEIN; LEPTOMYCIN B; REGULATOR PROTEIN; SIGNAL PEPTIDE;

ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL NUCLEUS; GLUCOKINASE; HELA CELLS; HUMANS; LIVER; PROTEIN SORTING SIGNALS; PROTEINS;

EID: 0033601256     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.52.37125     Document Type: Article

References (49)

1. Printz, R. L., Magnuson, M. A., and Granner, D. K. (1993) Annu. Rev. Nutr 13, 463-496
2. O'Doherty, R. M., Lehman, D. L., Seoane, J., Gomez-Foix, A. M., Guinovart, J. J., and Newgard, C. B. (1996) J. Biol. Chem. 271, 20524-20530
3. Ferre, T., Riu, E., Bosch, F., and Valera, A. (1996) FASEB J. 10, 1213-1218
4. Hariharan, N., Farrelly, D., Hagan, D., Hillyer, D., Arbeeny, C., Sabrah, T., Treloar, A., Brown, K., Kalinowski, S., and Mookhtiar, K. (1997) Diabetes 46, 11-16
5. Niswender, K. D., Shiota, M., Postic, C., Cherrington, A. D., and Magnuson, M. A. (1997) J. Biol. Chem. 272, 22570-22575
6. Postic, C., Shiota, M., Niswender, K. D., Jetton, T. L., Chen, Y., Moates, J. M., Shelton, K. D., Lindner, J., Cherrington, A. D., and Magnuson, M. A. (1999) J. Biol. Chem. 274, 305-315
7. Iynedjian, P. B., Ucla, C., and Mach, B. (1987) J. Biol. Chem. 262, 6032-6038
8. Iynedjian, P. B., Gjinovci, A., and Renold, A. E. (1988) J. Biol. Chem. 263, 740-744
9. Magnuson, M. A., Andreone, T. L., Printz, R. L., Koch, S., and Granner, D. K. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 4838-4842
10. Bedoya, F. J., Matschinsky, F. M., Shimizu, T., O'Neil, J. J., and Appel, M. C. (1986) J. Biol. Chem. 261, 10760-10764
11. Van Schaflingen, E., Vandercammen, A., Detheux, M., and Davies, D. R. (1992) Adv. Enzyme Regul. 32, 133-148
12. Vandercammen, A., and Van Schaftingen, E. (1993) Biochem. J. 294, 551-556
13. Van Schaftingen, E. (1989) Eur. J. Biochem. 179, 179-184
14. Agius, L., and Peak, M. (1993) Biochem. J. 296, 785-796
15. Agius, L., Peak, M., and Van Schaftingen, E. (1995) Biochem. J. 309, 711-713
16. Brown, K. S., Kalinowski, S. S., Megill, J. H., Durham, S. K., and Mookhtiar, K. A. (1997) Diabetes 46, 179-186
17. Toyoda, Y., Miwa, I., Kamiya, M., Ogiso, S., Nonogaki, T., Aoki, S., and Okuda, J. (1994) Biochem. Biophys. Res. Commun. 204, 252-256
18. Toyoda, Y., Miwa, I., Kamiya, M., Ogiso, S., Nonogaki, T., Aoki, S., and Okuda, J. (1995) Histochem. Cell Biol. 103, 31-38
19. Feldherr, C. M., Kallenbach, E., and Schultz, N. (1984) J. Cell Biol. 99, 2216-2222
20. Dworetzky, S. I., and Feldherr, C. M. (1988) J. Cell Biol. 106, 575-584
21. Peters, R. (1986) Biochim. Biophys. Acta 864, 305-359
22. Gerace, L. (1992) Curr. Opin. Cell Biol. 4, 637-645
23. Gerace, L. (1995) Cell 82, 341-344
24. Ullman, K. S., Powers, M. A., and Forbes, D. J. (1997) Cell 90, 967-970
25. Andreone, T. L., Printz, R. L., Pilkis, S. J., Magnuson, M. A., and Granner, D. K. (1989) J. Biol. Chem. 264, 363-369
26. Liang, Y., Jetton, T. L., Zimmerman, E. C., Najafi, H., Matschinsky, F. M., and Magnuson, M. A. (1991) J. Biol. Chem. 266, 6999-7007
27. Jetton, T. L., Liang, Y., Pettepher, C. C., Zimmerman, E. C., Cox, F. G., Horvath, K., Matschinsky, F. M., and Magnuson, M. A. (1994) J. Biol. Chem. 269, 3641-3654
28. Jetton, T. L., and Magnuson, M. A. (1992) Proc. Natl. Acad. Sci. U. S.A. 89, 2619-2623
29. Fields, S., and Song, O. (1989) Nature 340, 245-246
30. Miller, J. H. (1992) A Short Course in Bacterial Genetics: A Laboratory Manual and Handbook for Escherichia coli and Related Bacteria, p. 74, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
31. Printz, R. L., Koch, S., Potter, L. R., O'Doherty, R. M., Tiesinga, J. J., Moritz, S., and Granner, D. K. (1993) J. Biol. Chem. 268, 5209-5219
32. Kogure, K., Shinohara, Y., and Terada, H. (1993) J. Biol. Chem. 268, 8422-8424
33. Ardehali, H., Printz, R. L., Whitesell, R. R., May, J. M., and Granner, D. K. (1999) J. Biol. Chem. 274, 15986-15989
34. Kogure, K., Yamamoto, K., Majima, E., Shinohara, Y., Yamashita, K., and Terada, H. (1996) J. Biol. Chem. 271, 15230-15236
35. Fischer, U., Huber, J., Boelens, W. C., Mattaj, I. W., and Luhrmann, R. (1995) Cell 82, 475-483
36. Wen, W., Meinkoth, J. L., Tsien, R. Y., and Taylor, S. S. (1995) Cell 82, 463-473
37. Fukuda, M., Gotoh, I., Gotoh, Y., and Nishida, E. (1996) J. Biol. Chem. 271, 20024-20028
38. Wada, A., Fukuda, M., Mishima, M., and Nishida, E. (1998) EMBO J. 17, 1635-1641
39. Nishi, K., Yoshida, M., Fujiwara, D., Nishikawa, M., Horinouchi, S., and Beppu, T. (1994) J. Biol. Chem. 269, 6320-6324
40. Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E. P., Yoneda, Y., Yanagida, M., Horinouchi, S., and Yoshida, M. (1998) Exp. Cell Res. 242, 540-547
41. Mizuno, T., Okamoto, T., Yokoi, M., Izumi, M., Kobayashi, A., Hachiya, T., Tamai, K., Inoue, T., and Hanaoka, F. (1996) Cell. Sci. 109, 2627-2636
42. Jans, D. A., Briggs, L. J., Gustin, S. E., Jans, P., Ford, S., and Young, I. G. (1997) FEBS Lett. 410, 368-372
43. Van Schaftingen, E., and Vandercammen, A. (1989) Eur. J. Biochem. 179, 173-177
44. Vandercammen, A., and Van Schaftingen, E. (1990) Eur. J. Biochem. 191, 483-489
45. Detheux, M., Vandercammen, A., and Van Schaftingen, E. (1991) Eur. J. Biochem. 200, 553-561
46. Gidh-Jain, M., Takeda, J., Xu, L. Z., Lange, A. J., Vionnet, N., Stoffel, M., Froguel, P., Velho, G., Sun, F., Cohen, D., Patel, P., Lo, Y.-M. D., Hattersley, A. T., Luthman, H., Wedell, A., St. Charles, R., Harrison, R. W., Weber, I. T., Bell, G. I., and Pilkis, S. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1932-1936
47. St. Charles, R., Harrison, R. W., Bell, G. I., Pilkis, S. J., and Weber, I. T. (1994) Diabetes 43, 784-791
48. Veiga-da-Cunha, M., Courtois, S., Michel, A., Gosselain, E., and Van Schaftingen, E. (1996) J. Biol. Chem. 27, 6292-6297
49. Veiga-da-Cunha, M., Xu, L. Z. Lee, Y. H., Marotta, D., Pilkis, S. J., and Van Schaftingen, E. (1996) Diabetologia 39, 1173-1179