Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations

Journal of Biological Chemistry

Volumn 281, Issue 52, 2006, Pages 40201-40207

  Heredia, Vladi V ^a   Carlson, Thomas J ^a   Garcia, Erin ^a   Sun, Shaoxian ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE (GK); GLUCOKINASE REGULATORY PROTEIN (GKRP); PROTEIN-PROTEIN INTERACTION;

CONFORMATIONS; ENZYMES; GLUCOSE; REACTION KINETICS;

BIOCHEMISTRY;

APOENZYME; GLUCOKINASE; GLUCOKINASE REGULATORY PROTEIN; GLUCOSE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME REGULATION; HYPOGLYCEMIA; KINETICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STEADY STATE;

ALLOSTERIC SITE; AMINO ACID SUBSTITUTION; APOENZYMES; BINDING, COMPETITIVE; CARRIER PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLUCOKINASE; GLUCOSE; HUMANS; KINETICS; POINT MUTATION; POLYMORPHISM, GENETIC; SPECTROPHOTOMETRY;

EID: 33846006251     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607987200     Document Type: Article

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