Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

Nucleic Acids Research

Volumn 43, Issue 10, 2015, Pages 5221-5235

  Newman, Joseph A ^a   Savitsky, Pavel ^a   Allerston, Charles K ^a,e   Bizard, Anna H ^b   Özer, Özgün ^b   Sarlós, Kata ^b   Liu, Ying ^b   Pardon, Els ^c,d   Steyaert, Jan ^c,d   Hickson, Ian D ^b   Gileadi, Opher ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e DART NEUROSCIENCE LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIMETHOXY 4 METHYLAMPHETAMINE; ANTIBODY; BLOOM SYNDROME HELICASE; DNA; DNA HELICASE; DOUBLE STRANDED DNA; NUCLEOTIDE; RECQ HELICASE; ADENOSINE DIPHOSPHATE; NANOBODY; ZINC;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; GENOME; HRDC DOMAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; CRYSTALLOGRAPHY, X-RAY; DNA; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECQ HELICASES; SINGLE-DOMAIN ANTIBODIES; ZINC;

EID: 84931275195     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv373     Document Type: Article

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