Critical interaction domains between bloom syndrome protein and RAD51

Protein Journal

Volumn 30, Issue 1, 2011, Pages 1-8

  Bergeron, Krystal L ^a   Murphy, Eileen L ^a   Brown, Lily W ^a   Almeida, Karen H ^a  

^a RHODE ISLAND COLLEGE   (United States)

Author keywords

Bloom syndrome; Cancer; Homologous recombination; Protein protein interaction; RAD51

Indexed keywords

BLOOM SYNDROME HELICASE; PEPTIDE FRAGMENT; RAD51 PROTEIN; SINGLE STRANDED DNA;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION;

EID: 79551511152     PISSN: 15723887     EISSN: 18758355     Source Type: Journal    
DOI: 10.1007/s10930-010-9295-8     Document Type: Article

References (26)

1. S Agarwal AA Tafel R Kanaar 2006 DNA double-strand break repair and chromosome translocations DNA Repair (Amst) 5 1075 1081 1:CAS:528: DC%2BD28XptFSrsbc%3D 10.1016/j.dnarep.2006.05.029 (Pubitemid 44291620)
2. CZ Bachrati ID Hickson 2003 RecQ helicases: suppressors of tumorigenesis and premature aging Biochem J 374 577 606 1:CAS:528:DC%2BD3sXntFamsb0%3D 10.1042/BJ20030491 (Pubitemid 37163904)
3. D Branzei M Foiani 2007 RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination Genes Dev 21 3019 3026 1:CAS:528:DC%2BD2sXhsVaht7rL 10.1101/gad.1624707 (Pubitemid 350223520)
4. DV Bugreev X Yu EH Egelman AV Mazin 2007 Novel pro- and anti-recombination activities of the Bloom's syndrome helicase Genes Dev 21 3085 3094 1:CAS:528:DC%2BD2sXhsVaht7vP 10.1101/gad.1609007 (Pubitemid 350223526)
5. CF Chen SJ Brill 2010 An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs EMBO J 29 1713 1725 1:CAS:528:DC%2BC3cXktlynsL4%3D 10.1038/emboj.2010.61
6. CF Cheok CZ Bachrati KL Chan C Ralf L Wu ID Hickson 2005 Roles of the Bloom's syndrome helicase in the maintenance of genome stability Biochem Soc Trans 33 1456 1459 1:CAS:528:DC%2BD2MXhtFCqsLjK 10.1042/BST20051456 (Pubitemid 41779714)
7. AR Davalos J Campisi 2003 Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks J Cell Biol 162 1197 1209 1:CAS:528:DC%2BD3sXnsl2jsLg%3D 10.1083/jcb.200304016 (Pubitemid 37210877)
8. AR Davalos P Kaminker RK Hansen J Campisi 2004 ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation Cell Cycle 3 1579 1586 1:CAS:528: DC%2BD28XjtVersbY%3D
9. T Helleday J Lo DC van Gent BP Engelward 2007 DNA double-strand break repair: from mechanistic understanding to cancer treatment DNA Repair (Amst) 6 923 935 1:CAS:528:DC%2BD2sXmt1yiu7s%3D 10.1016/j.dnarep.2007.02.006 (Pubitemid 46880473)
10. JH Hoeijmakers 2001 Genome maintenance mechanisms for preventing cancer Nature 411 366 374 1:CAS:528:DC%2BD3MXktVSjs74%3D 10.1038/35077232 (Pubitemid 32467046)
11. JH Hoeijmakers 2009 DNA damage, aging, and cancer N Engl J Med 361 1475 1485 1:CAS:528:DC%2BD1MXht1GiurbK 10.1056/NEJMra0804615
12. G Langland J Kordich J Creaney KH Goss K Lillard-Wetherell K Bebenek TA Kunkel J Groden 2001 The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair J Biol Chem 276 30031 30035 1:CAS:528:DC%2BD3MXmtFehsL0%3D 10.1074/jbc.M009664200
13. X Li WD Heyer 2008 Homologous recombination in DNA repair and DNA damage tolerance Cell Res 18 99 113 1:CAS:528:DC%2BD1cXisVSjsw%3D%3D 10.1038/cr.2008.1
14. HW Mankouri ID Hickson 2007 The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'? Trends Biochem Sci 32 538 546 1:CAS:528:DC%2BD2sXhtlGht7zI 10.1016/j.tibs.2007.09.009 (Pubitemid 350123052)
15. FJ Mao JM Sidorova JM Lauper MJ Emond RJ Monnat 2010 The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage Cancer Res 70 6548 6555 1:CAS:528: DC%2BC3cXhtVWqu7nK 10.1158/0008-5472.CAN-10-0475
16. H Nakayama 2002 RecQ family helicases: roles as tumor suppressor proteins Oncogene 21 9008 9021 1:CAS:528:DC%2BD38XpsFShu7o%3D 10.1038/sj.onc.1205959 (Pubitemid 36110829)
17. G Pedrazzi C Perrera H Blaser P Kuster G Marra SL Davies GH Ryu R Freire ID Hiskson J Jiricny I Stagljar 2001 Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1 Nucleic Acids Res 29 4378 4386 1:CAS:528:DC%2BD3MXovFalsL8%3D 10.1093/nar/29.21.4378
18. S Sharma JA Sommers L Wu VA Bohr ID Hickson RM Brosh Jr 2004 Stimulation of flap endonuclease-1 by the Bloom's syndrome protein J Biol Chem 279 9847 9856 1:CAS:528:DC%2BD2cXhvFChtbY%3D 10.1074/jbc.M309898200 (Pubitemid 38372583)
19. P Sung H Klein 2006 Mechanism of homologous recombination: mediators and helicases take on regulatory functions Nat Rev Mol Cell Biol 7 739 750 1:CAS:528:DC%2BD28XpvVCmur8%3D 10.1038/nrm2008 (Pubitemid 44450458)
20. P Sung L Krejci S Van Komen MG Sehorn 2003 Rad51 recombinase and recombination mediators J Biol Chem 278 42729 42732 1:CAS:528: DC%2BD3sXosFSksLY%3D 10.1074/jbc.R300027200 (Pubitemid 37345880)
21. Y Wang D Cortez P Yazdi N Neff SJ Elledge J Qin 2000 BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures Genes Dev 14 927 939 1:CAS:528:DC%2BD3cXivFyltrw%3D
22. SC West 2003 Molecular views of recombination proteins and their control Nat Rev Mol Cell Biol 4 435 445 1:CAS:528:DC%2BD3sXktFOnsrY%3D 10.1038/nrm1127 (Pubitemid 36648589)
23. MC Whitby 2005 Making crossovers during meiosis Biochem Soc Trans 33 1451 1455 1:CAS:528:DC%2BD2MXhtFCqsLjJ 10.1042/BST20051451 (Pubitemid 41779713)
24. L Wu SL Davies NC Levitt ID Hickson 2001 Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51 J Biol Chem 276 19375 19381 1:CAS:528:DC%2BD3MXkt12rtr4%3D 10.1074/jbc.M009471200
25. L Wu SL Davies PS North H Goulaouic JF Riou H Turley KC Gatter ID Hickson 2000 The Bloom's syndrome gene product interacts with topoisomerase III J Biol Chem 275 9636 9644 1:CAS:528:DC%2BD3cXitlCqs7w%3D 10.1074/jbc.275.13.9636 (Pubitemid 30185196)
26. JG Yodh BC Stevens R Kanagaraj P Janscak T Ha 2009 BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation EMBO J 28 405 416 1:CAS:528:DC%2BD1MXosVWlug%3D%3D 10.1038/emboj.2008.298