Characterization and mutational analysis of the RecQ core of the bloom syndrome protein

Journal of Molecular Biology

Volumn 330, Issue 1, 2003, Pages 29-42

  Janscak, Pavel ^a,b   Garcia, Patrick L ^b   Hamburger, Fabienne ^a   Makuta, Yoko ^c   Shiraishi, Kouya ^c   Imai, Yukiho ^c   Ikeda, Hideo ^c   Bickle, Thomas A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c Medinet Medical Institute   (Japan)

Author keywords

Bloom syndrome; DNA helicase; Genomic instability; Illegitimate recombination; Mutagenesis

Indexed keywords

BLOOM SYNDROME PROTEIN; HELICASE; PROTEIN; RECQ HELICASE; UNCLASSIFIED DRUG; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ADENOSINE 5'-O-(3-THIOTRIPHOSPHATE); ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; DRUG DERIVATIVE; MAGNESIUM; RECOMBINANT PROTEIN; RECQ PROTEIN, E COLI; RECQL PROTEIN, HUMAN;

ARTICLE; BLOOM SYNDROME; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; ESCHERICHIA COLI; GEL FILTRATION; GENE DELETION; GENE MUTATION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; BIOCHEMISTRY; CHEMISTRY; ENZYME SPECIFICITY; GENETIC RECOMBINATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SOLUTION AND SOLUBILITY; STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BIOCHEMISTRY; DNA HELICASES; ESCHERICHIA COLI; HUMANS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; RECQ HELICASES; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0038004735     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00534-5     Document Type: Article

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