-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
-
Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136(5):E359-86
-
(2015)
Int J Cancer
, vol.136
, Issue.5
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
-
2
-
-
84859212951
-
Hepatocellular carcinoma
-
Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet 2012;379(9822):1245-55
-
(2012)
Lancet
, vol.379
, Issue.9822
, pp. 1245-1255
-
-
Forner, A.1
Llovet, J.M.2
Bruix, J.3
-
3
-
-
84860240078
-
Targeted therapy of hepatocellular carcinoma: Present and future
-
Chan SL, Yeo W. Targeted therapy of hepatocellular carcinoma: present and future. J Gastroenterol Hepatol 2012;27(5):862-72
-
(2012)
J Gastroenterol Hepatol
, vol.27
, Issue.5
, pp. 862-872
-
-
Chan, S.L.1
Yeo, W.2
-
4
-
-
58749090909
-
New utility of an old marker: Serial alpha-fetoprotein measurement in predicting radiologic response and survival of patients with hepatocellular carcinoma undergoing systemic chemotherapy
-
Chan SL, Mo FK, Johnson PJ, et al. New utility of an old marker: serial alpha-fetoprotein measurement in predicting radiologic response and survival of patients with hepatocellular carcinoma undergoing systemic chemotherapy. J Clin Oncol 2009;27(3):446-52
-
(2009)
J Clin Oncol
, vol.27
, Issue.3
, pp. 446-452
-
-
Chan, S.L.1
Mo, F.K.2
Johnson, P.J.3
-
5
-
-
84891587587
-
Randomized, multicenter, open-label study of oxaliplatin plus fluorouracil/ leucovorin versus doxorubicin as palliative chemotherapy in patients with advanced hepatocellular carcinoma from Asia
-
Qin S, Bai Y, Lim HY, et al. Randomized, multicenter, open-label study of oxaliplatin plus fluorouracil/ leucovorin versus doxorubicin as palliative chemotherapy in patients with advanced hepatocellular carcinoma from Asia. J Clin Oncol 2013;31(28):3501-8
-
(2013)
J Clin Oncol
, vol.31
, Issue.28
, pp. 3501-3508
-
-
Qin, S.1
Bai, Y.2
Lim, H.Y.3
-
6
-
-
84908556046
-
Drug development for hepatocellular carcinoma: Knowing the past helps to understand the future
-
Chan SL. Drug development for hepatocellular carcinoma: knowing the past helps to understand the future. Oncologist 2014;19(11):1115-17
-
(2014)
Oncologist
, vol.19
, Issue.11
, pp. 1115-1117
-
-
Chan, S.L.1
-
7
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359(4):378-90
-
(2008)
N Engl J Med
, vol.359
, Issue.4
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
8
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A Phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A Phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009;10(1):25-34
-
(2009)
Lancet Oncol
, vol.10
, Issue.1
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
9
-
-
84871986560
-
Medical therapies for hepatocellular carcinoma: A critical view of the evidence
-
Villanueva A, Hernandez-Gea V, Llovet JM. Medical therapies for hepatocellular carcinoma: A critical view of the evidence. Nat Rev Gastroenterol Hepatol 2013;10(1):34-42
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, Issue.1
, pp. 34-42
-
-
Villanueva, A.1
Hernandez-Gea, V.2
Llovet, J.M.3
-
10
-
-
84896977908
-
Development of systemic therapy for hepatocellular carcinoma at 2013: Updates and insights
-
Chan SL, Yeo W. Development of systemic therapy for hepatocellular carcinoma at 2013: updates and insights. World J Gastroenterol 2014;20(12):3135-45
-
(2014)
World J Gastroenterol
, vol.20
, Issue.12
, pp. 3135-3145
-
-
Chan, S.L.1
Yeo, W.2
-
11
-
-
79959214127
-
Phase II study of the mitogen-activated protein kinase 1/2 inhibitor selumetinib in patients with advanced hepatocellular carcinoma
-
O'Neil BH, Goff LW, Kauh JS, et al. Phase II study of the mitogen-activated protein kinase 1/2 inhibitor selumetinib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2011;29(17):2350-6
-
(2011)
J Clin Oncol
, vol.29
, Issue.17
, pp. 2350-2356
-
-
O'neil, B.H.1
Goff, L.W.2
Kauh, J.S.3
-
12
-
-
84903593280
-
Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: The EVOLVE-1 randomized clinical trial
-
Zhu AX, Kudo M, Assenat E, et al. Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: The EVOLVE-1 randomized clinical trial. Jama 2014;312(1):57-67
-
(2014)
Jama
, vol.312
, Issue.1
, pp. 57-67
-
-
Zhu, A.X.1
Kudo, M.2
Assenat, E.3
-
13
-
-
84892493984
-
A Phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma
-
Abou-Alfa GK, Capanu M, O'Reilly EM, et al. A Phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma. J Hepatol 2014;60(2):319-24
-
(2014)
J Hepatol
, vol.60
, Issue.2
, pp. 319-324
-
-
Abou-Alfa, G.K.1
Capanu, M.2
O'reilly, E.M.3
-
14
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard C, Amaddeo G, Imbeaud S, et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 2012;44(6):694-8
-
(2012)
Nat Genet
, vol.44
, Issue.6
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
-
15
-
-
84862976633
-
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
-
Fujimoto A, Totoki Y, Abe T, et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 2012;44(7):760-4
-
(2012)
Nat Genet
, vol.44
, Issue.7
, pp. 760-764
-
-
Fujimoto, A.1
Totoki, Y.2
Abe, T.3
-
16
-
-
0034807926
-
The processing and utilization of hepatocyte growth factor/ scatter factor following partial hepatectomy in the rat
-
Pediaditakis P, Lopez-Talavera JC, Petersen B, et al. The processing and utilization of hepatocyte growth factor/ scatter factor following partial hepatectomy in the rat. Hepatology 2001;34(4 Pt 1):688-93
-
(2001)
Hepatology
, vol.34
, Issue.4
, pp. 688-693
-
-
Pediaditakis, P.1
Lopez-Talavera, J.C.2
Petersen, B.3
-
17
-
-
0021241398
-
Molecular cloning of a new transforming gene from a chemically transformed human cell line
-
Cooper CS, Park M, Blair DG, et al. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 1984;311(5981):29-33
-
(1984)
Nature
, vol.311
, Issue.5981
, pp. 29-33
-
-
Cooper, C.S.1
Park, M.2
Blair, D.G.3
-
18
-
-
84856152266
-
Targeting MET in cancer: Rationale and progress
-
Gherardi E, Birchmeier W, Birchmeier C, et al. Targeting MET in cancer: rationale and progress. Nat Rev Cancer 2012;12(2):89-103
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.2
, pp. 89-103
-
-
Gherardi, E.1
Birchmeier, W.2
Birchmeier, C.3
-
19
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh CG, Factor VM, Sanchez A, et al. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci USA 2004;101(13):4477-82
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.13
, pp. 4477-4482
-
-
Huh, C.G.1
Factor, V.M.2
Sanchez, A.3
-
20
-
-
33745220780
-
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
-
Kaposi-Novak P, Lee JS, Gomez-Quiroz L, et al. Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest 2006;116(6):1582-95
-
(2006)
J Clin Invest
, vol.116
, Issue.6
, pp. 1582-1595
-
-
Kaposi-Novak, P.1
Lee, J.S.2
Gomez-Quiroz, L.3
-
21
-
-
0033867263
-
U-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma
-
Tavian D, De Petro G, Benetti A, et al. u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma. Int J Cancer 2000;87(5):644-9
-
(2000)
Int J Cancer
, vol.87
, Issue.5
, pp. 644-649
-
-
Tavian, D.1
De Petro, G.2
Benetti, A.3
-
22
-
-
84892549017
-
Met as a therapeutic target in HCC: Facts and hopes
-
Giordano S, Columbano A. Met as a therapeutic target in HCC: facts and hopes. J Hepatol 2014;60(2):442-52
-
(2014)
J Hepatol
, vol.60
, Issue.2
, pp. 442-452
-
-
Giordano, S.1
Columbano, A.2
-
23
-
-
80052033164
-
C-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma
-
You H, Ding W, Dang H, et al. c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma. Hepatology 2011;54(3):879-89
-
(2011)
Hepatology
, vol.54
, Issue.3
, pp. 879-889
-
-
You, H.1
Ding, W.2
Dang, H.3
-
24
-
-
70350230210
-
Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases
-
Qian F, Engst S, Yamaguchi K, et al. Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases. Cancer Res 2009;69(20):8009-16
-
(2009)
Cancer Res
, vol.69
, Issue.20
, pp. 8009-8016
-
-
Qian, F.1
Engst, S.2
Yamaguchi, K.3
-
25
-
-
83355166909
-
Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
-
Yakes FM, Chen J, Tan J, et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther 2011;10(12):2298-308
-
(2011)
Mol Cancer Ther
, vol.10
, Issue.12
, pp. 2298-2308
-
-
Yakes, F.M.1
Chen, J.2
Tan, J.3
-
26
-
-
84890283023
-
Developing biomarkers to predict benefit from HGF/MET pathway inhibitors
-
Koeppen H, Rost S, Yauch RL. Developing biomarkers to predict benefit from HGF/MET pathway inhibitors. J Pathol 2014;232(2):210-18
-
(2014)
J Pathol
, vol.232
, Issue.2
, pp. 210-218
-
-
Koeppen, H.1
Rost, S.2
Yauch, R.L.3
-
27
-
-
0011280342
-
Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction
-
Wilks AF. Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction. Proc Natl Acad Sci USA 1989;86(5):1603-7
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.5
, pp. 1603-1607
-
-
Wilks, A.F.1
-
28
-
-
0024989359
-
Tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
-
Firmbach-Kraft I, Byers M, Shows T, et al. tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 1990;5(9):1329-36
-
(1990)
Oncogene
, vol.5
, Issue.9
, pp. 1329-1336
-
-
Firmbach-Kraft, I.1
Byers, M.2
Shows, T.3
-
29
-
-
84904638434
-
The molecular regulation of Janus kinase (JAK) activation
-
Babon JJ, Lucet IS, Murphy JM, et al. The molecular regulation of Janus kinase (JAK) activation. Biochem J 2014;462(1):1-13
-
(2014)
Biochem J
, vol.462
, Issue.1
, pp. 1-13
-
-
Babon, J.J.1
Lucet, I.S.2
Murphy, J.M.3
-
30
-
-
33645976174
-
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
-
Calvisi DF, Ladu S, Gorden A, et al. Ubiquitous activation of Ras and Jak/Stat pathways in human HCC. Gastroenterology 2006;130(4):1117-28
-
(2006)
Gastroenterology
, vol.130
, Issue.4
, pp. 1117-1128
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
-
31
-
-
27144433826
-
Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
-
Niwa Y, Kanda H, Shikauchi Y, et al. Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene 2005;24(42):6406-17
-
(2005)
Oncogene
, vol.24
, Issue.42
, pp. 6406-6417
-
-
Niwa, Y.1
Kanda, H.2
Shikauchi, Y.3
-
32
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa H, Matsubara K, Qian GS, et al. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet 2001;28(1):29-35
-
(2001)
Nat Genet
, vol.28
, Issue.1
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
-
33
-
-
0032566516
-
HBx protein of hepatitis B virus activates Jak1-STAT signaling
-
Lee YH, Yun Y. HBx protein of hepatitis B virus activates Jak1-STAT signaling. J Biol Chem 1998;273(39):25510-15
-
(1998)
J Biol Chem
, vol.273
, Issue.39
, pp. 25510-25515
-
-
Lee, Y.H.1
Yun, Y.2
-
34
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S, Kantarjian H, Mesa RA, et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med 2010;363(12):1117-27
-
(2010)
N Engl J Med
, vol.363
, Issue.12
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
-
35
-
-
84887132275
-
Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro
-
Wilson GS, Tian A, Hebbard L, et al. Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro. Cancer Lett 2013;341(2):224-30
-
(2013)
Cancer Lett
, vol.341
, Issue.2
, pp. 224-230
-
-
Wilson, G.S.1
Tian, A.2
Hebbard, L.3
-
36
-
-
84883718528
-
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
-
Kan Z, Zheng H, Liu X, et al. Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res 2013;23(9):1422-33
-
(2013)
Genome Res
, vol.23
, Issue.9
, pp. 1422-1433
-
-
Kan, Z.1
Zheng, H.2
Liu, X.3
-
37
-
-
34848866633
-
Liver-specific activities of FGF19 require Klotho beta
-
Lin BC, Wang M, Blackmore C, et al. Liver-specific activities of FGF19 require Klotho beta. J Biol Chem 2007;282(37):27277-84
-
(2007)
J Biol Chem
, vol.282
, Issue.37
, pp. 27277-27284
-
-
Lin, B.C.1
Wang, M.2
Blackmore, C.3
-
38
-
-
77957376253
-
Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse
-
Fon Tacer K, Bookout AL, Ding X, et al. Research resource: comprehensive expression atlas of the fibroblast growth factor system in adult mouse. Mol Endocrinol 2010;24(10):2050-64
-
(2010)
Mol Endocrinol
, vol.24
, Issue.10
, pp. 2050-2064
-
-
Fon Tacer, K.1
Bookout, A.L.2
Ding, X.3
-
40
-
-
0036086285
-
A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
-
Nicholes K, Guillet S, Tomlinson E, et al. A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. Am J Pathol 2002;160(6):2295-307
-
(2002)
Am J Pathol
, vol.160
, Issue.6
, pp. 2295-2307
-
-
Nicholes, K.1
Guillet, S.2
Tomlinson, E.3
-
41
-
-
84856565638
-
Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma
-
Miura S, Mitsuhashi N, Shimizu H, et al. Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma. BMC Cancer 2012;12:56
-
(2012)
BMC Cancer
, vol.12
, pp. 56
-
-
Miura, S.1
Mitsuhashi, N.2
Shimizu, H.3
-
42
-
-
84866171951
-
Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models
-
French DM, Lin BC, Wang M, et al. Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models. PLoS One 2012;7(5):e36713
-
(2012)
PLoS One
, vol.7
, Issue.5
, pp. e36713
-
-
French, D.M.1
Lin, B.C.2
Wang, M.3
-
43
-
-
37849029159
-
Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
-
Desnoyers LR, Pai R, Ferrando RE, et al. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene 2008;27(1):85-97
-
(2008)
Oncogene
, vol.27
, Issue.1
, pp. 85-97
-
-
Desnoyers, L.R.1
Pai, R.2
Ferrando, R.E.3
-
44
-
-
84933280522
-
First isoform selective inhibitor of FGFR4 for the treatment of genomically defined patients with hepatocellular carcinoma
-
AACR Annual Meeting LB-324
-
Hagel M, Miduturu C, Sheets M, et al. First isoform selective inhibitor of FGFR4 for the treatment of genomically defined patients with hepatocellular carcinoma. Cancer Res 2014;74(AACR Annual Meeting):LB-324
-
(2014)
Cancer Res
, vol.74
-
-
Hagel, M.1
Miduturu, C.2
Sheets, M.3
-
45
-
-
84931086428
-
Characterisation of AZ709, a potent and selective inhibitor of Fibroblast Growth Factor Receptor 4 (FGFR4)
-
Mooney L, Shea K, Cross S, et al. Characterisation of AZ709, a potent and selective inhibitor of Fibroblast Growth Factor Receptor 4 (FGFR4). NCRI Cancer Conference 2013;B211
-
(2013)
NCRI Cancer Conference
, pp. B211
-
-
Mooney, L.1
Shea, K.2
Cross, S.3
-
46
-
-
84902547039
-
Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; Translational safety considerations
-
Mellor HR. Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations. Liver Int 2014;34(6):e1-9
-
(2014)
Liver Int
, vol.34
, Issue.6
, pp. e1-9
-
-
Mellor, H.R.1
-
47
-
-
63949083417
-
Spontaneous regression of hepatocellular carcinoma: Three case reports and a categorized review of the literature
-
Oquinena S, Inarrairaegui M, Vila JJ, et al. Spontaneous regression of hepatocellular carcinoma: three case reports and a categorized review of the literature. Dig Dis Sci 2009;54(5):1147-53
-
(2009)
Dig Dis Sci
, vol.54
, Issue.5
, pp. 1147-1153
-
-
Oquinena, S.1
Inarrairaegui, M.2
Vila, J.J.3
-
48
-
-
79952701792
-
Potential of immunotherapy for hepatocellular carcinoma
-
Breous E, Thimme R. Potential of immunotherapy for hepatocellular carcinoma. J Hepatol 2011;54(4):830-4
-
(2011)
J Hepatol
, vol.54
, Issue.4
, pp. 830-834
-
-
Breous, E.1
Thimme, R.2
-
49
-
-
84864651241
-
A study of circulating interleukin 10 in prognostication of unresectable hepatocellular carcinoma
-
Chan SL, Mo FK, Wong CS, et al. A study of circulating interleukin 10 in prognostication of unresectable hepatocellular carcinoma. Cancer 2012;118(16):3984-92
-
(2012)
Cancer
, vol.118
, Issue.16
, pp. 3984-3992
-
-
Chan, S.L.1
Mo, F.K.2
Wong, C.S.3
-
50
-
-
0035056017
-
CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
-
Chambers CA, Kuhns MS, Egen JG, et al. CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu Rev Immunol 2001;19:565-94
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 565-594
-
-
Chambers, C.A.1
Kuhns, M.S.2
Egen, J.G.3
-
51
-
-
38549089084
-
The reverse stop-signal model for CTLA4 function
-
Rudd CE. The reverse stop-signal model for CTLA4 function. Nat Rev Immunol 2008;8(2):153-60
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.2
, pp. 153-160
-
-
Rudd, C.E.1
-
52
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12(4):252-64
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
53
-
-
82255192901
-
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
-
Walker LS, Sansom DM. The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol 2011;11(12):852-63
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 852-863
-
-
Walker, L.S.1
Sansom, D.M.2
-
54
-
-
76049092889
-
Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma
-
Kirkwood JM, Lorigan P, Hersey P, et al. Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma. Clin Cancer Res 2010;16(3):1042-8
-
(2010)
Clin Cancer Res
, vol.16
, Issue.3
, pp. 1042-1048
-
-
Kirkwood, J.M.1
Lorigan, P.2
Hersey, P.3
-
55
-
-
84879141840
-
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
-
Sangro B, Gomez-Martin C, de la Mata M, et al. A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C. J Hepatol 2013;59(1):81-8
-
(2013)
J Hepatol
, vol.59
, Issue.1
, pp. 81-88
-
-
Sangro, B.1
Gomez-Martin, C.2
De La Mata, M.3
-
56
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y, Kawasaki A, Nishimura H, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996;8(5):765-72
-
(1996)
Int Immunol
, vol.8
, Issue.5
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
-
57
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe AH, Wherry EJ, Ahmed R, et al. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007;8(3):239-45
-
(2007)
Nat Immunol
, vol.8
, Issue.3
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
-
58
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir ME, Liang SC, Guleria I, et al. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 2006;203(4):883-95
-
(2006)
J Exp Med
, vol.203
, Issue.4
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
-
59
-
-
42449147063
-
PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma
-
Yamamoto R, Nishikori M, Kitawaki T, et al. PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma. Blood 2008;111(6):3220-4
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3220-3224
-
-
Yamamoto, R.1
Nishikori, M.2
Kitawaki, T.3
-
60
-
-
34250177269
-
PD-1 is expressed by tumorinfiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
-
Thompson RH, Dong H, Lohse CM, et al. PD-1 is expressed by tumorinfiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res 2007;13(6):1757-61
-
(2007)
Clin Cancer Res
, vol.13
, Issue.6
, pp. 1757-1761
-
-
Thompson, R.H.1
Dong, H.2
Lohse, C.M.3
-
61
-
-
33847611968
-
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
-
Hamanishi J, Mandai M, Iwasaki M, et al. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci USA 2007;104(9):3360-5
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3360-3365
-
-
Hamanishi, J.1
Mandai, M.2
Iwasaki, M.3
-
62
-
-
34247532726
-
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
-
Nomi T, Sho M, Akahori T, et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin Cancer Res 2007;13(7):2151-7
-
(2007)
Clin Cancer Res
, vol.13
, Issue.7
, pp. 2151-2157
-
-
Nomi, T.1
Sho, M.2
Akahori, T.3
-
63
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013;369(2):134-44
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
64
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366(26):2443-54
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
65
-
-
78449243490
-
Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy
-
Callahan MK, Wolchok JD, Allison JP. Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy. Semin Oncol 2010;37(5):473-84
-
(2010)
Semin Oncol
, vol.37
, Issue.5
, pp. 473-484
-
-
Callahan, M.K.1
Wolchok, J.D.2
Allison, J.P.3
-
66
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014;515(7528):563-7
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
-
67
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128(4):683-92
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
68
-
-
44449114668
-
Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells
-
Yoo YG, Na TY, Seo HW, et al. Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells. Oncogene 2008;27(24):3405-13
-
(2008)
Oncogene
, vol.27
, Issue.24
, pp. 3405-3413
-
-
Yoo, Y.G.1
Na, T.Y.2
Seo, H.W.3
-
69
-
-
58149310908
-
Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A
-
Zheng DL, Zhang L, Cheng N, et al. Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. J Hepatol 2009;50(2):377-87
-
(2009)
J Hepatol
, vol.50
, Issue.2
, pp. 377-387
-
-
Zheng, D.L.1
Zhang, L.2
Cheng, N.3
-
70
-
-
1642453460
-
Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101
-
Plumb JA, Finn PW, Williams RJ, et al. Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101. Mol Cancer Ther 2003;2(8):721-8
-
(2003)
Mol Cancer Ther
, vol.2
, Issue.8
, pp. 721-728
-
-
Plumb, J.A.1
Finn, P.W.2
Williams, R.J.3
-
71
-
-
77952240320
-
The preclinical activity of the histone deacetylase inhibitor PXD101 (belinostat) in hepatocellular carcinoma cell lines
-
Ma BB, Sung F, Tao Q, et al. The preclinical activity of the histone deacetylase inhibitor PXD101 (belinostat) in hepatocellular carcinoma cell lines. Invest New Drugs 2010;28(2):107-14
-
(2010)
Invest New Drugs
, vol.28
, Issue.2
, pp. 107-114
-
-
Ma, B.B.1
Sung, F.2
Tao, Q.3
-
72
-
-
84866758581
-
Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: A multicenter Phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group
-
Yeo W, Chung HC, Chan SL, et al. Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: A multicenter Phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group. J Clin Oncol 2012;30(27):3361-7
-
(2012)
J Clin Oncol
, vol.30
, Issue.27
, pp. 3361-3367
-
-
Yeo, W.1
Chung, H.C.2
Chan, S.L.3
-
73
-
-
84885911845
-
Efficacy, safety, tolerability, and PK of the HDAC inhibitor resminostat in sorafenib-refractory hepatocellular carcinoma (HCC): Phase II SHELTER study
-
abstr 4115
-
Bitzer M, Horger M, Lauer UM, et al. Efficacy, safety, tolerability, and PK of the HDAC inhibitor resminostat in sorafenib-refractory hepatocellular carcinoma (HCC): Phase II SHELTER study. J Clin Oncol 2012;30:Suppl; abstr 4115
-
(2012)
J Clin Oncol
, vol.30
-
-
Bitzer, M.1
Horger, M.2
Lauer, U.M.3
-
74
-
-
77950877402
-
HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy
-
Khan O, Fotheringham S, Wood V, et al. HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy. Proc Natl Acad Sci USA 2010;107(14):6532-7
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.14
, pp. 6532-6537
-
-
Khan, O.1
Fotheringham, S.2
Wood, V.3
-
75
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3(10):721-32
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.10
, pp. 721-732
-
-
Semenza, G.L.1
-
76
-
-
73249152662
-
Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery
-
Dai CX, Gao Q, Qiu SJ, et al. Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery. BMC Cancer 2009;9:418
-
(2009)
BMC Cancer
, vol.9
, pp. 418
-
-
Dai, C.X.1
Gao, Q.2
Qiu, S.J.3
-
77
-
-
0346689991
-
Hexokinase II and VEGF expression in liver tumors: Correlation with hypoxiainducible factor 1 alpha and its significance
-
Yasuda S, Arii S, Mori A, et al. Hexokinase II and VEGF expression in liver tumors: correlation with hypoxiainducible factor 1 alpha and its significance. J Hepatol 2004;40(1):117-23
-
(2004)
J Hepatol
, vol.40
, Issue.1
, pp. 117-123
-
-
Yasuda, S.1
Arii, S.2
Mori, A.3
-
78
-
-
84890460358
-
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex i
-
Ellinghaus P, Heisler I, Unterschemmann K, et al. BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I. Cancer Med 2013;2(5):611-24
-
(2013)
Cancer Med
, vol.2
, Issue.5
, pp. 611-624
-
-
Ellinghaus, P.1
Heisler, I.2
Unterschemmann, K.3
-
79
-
-
56249131779
-
A RNA antagonist of hypoxiainducible factor-1alpha, EZN-2968, inhibits tumor cell growth
-
Greenberger LM, Horak ID, Filpula D, et al. A RNA antagonist of hypoxiainducible factor-1alpha, EZN-2968, inhibits tumor cell growth. Mol Cancer Ther 2008;7(11):3598-608
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.11
, pp. 3598-3608
-
-
Greenberger, L.M.1
Horak, I.D.2
Filpula, D.3
-
80
-
-
34247160536
-
Role of hypoxia-inducible factor-alpha in hepatitis-B-virus X protein-mediated MDR1 activation
-
Han HK, Han CY, Cheon EP, et al. Role of hypoxia-inducible factor-alpha in hepatitis-B-virus X protein-mediated MDR1 activation. Biochem Biophys Res Commun 2007;357(2):567-73
-
(2007)
Biochem Biophys Res Commun
, vol.357
, Issue.2
, pp. 567-573
-
-
Han, H.K.1
Han, C.Y.2
Cheon, E.P.3
-
81
-
-
2142857253
-
Blocking endogenous glypican-3 expression releases Hep 3B cells from G1 arrest
-
Farooq M, Hwang SY, Park MK, et al. Blocking endogenous glypican-3 expression releases Hep 3B cells from G1 arrest. Mol Cells 2003;15(3):356-60
-
(2003)
Mol Cells
, vol.15
, Issue.3
, pp. 356-360
-
-
Farooq, M.1
Hwang, S.Y.2
Park, M.K.3
-
82
-
-
0035086268
-
Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders
-
Zhu ZW, Friess H, Wang L, et al. Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders. Gut 2001;48(4):558-64
-
(2001)
Gut
, vol.48
, Issue.4
, pp. 558-564
-
-
Zhu, Z.W.1
Friess, H.2
Wang, L.3
-
83
-
-
0038786861
-
Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma
-
Capurro M, Wanless IR, Sherman M, et al. Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma. Gastroenterology 2003;125(1):89-97
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 89-97
-
-
Capurro, M.1
Wanless, I.R.2
Sherman, M.3
-
84
-
-
27944433471
-
The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma
-
Yamauchi N, Watanabe A, Hishinuma M, et al. The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma. Mod Pathol 2005;18(12):1591-8
-
(2005)
Mod Pathol
, vol.18
, Issue.12
, pp. 1591-1598
-
-
Yamauchi, N.1
Watanabe, A.2
Hishinuma, M.3
-
85
-
-
22244480967
-
Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling
-
Capurro MI, Xiang YY, Lobe C, et al. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res 2005;65(14):6245-54
-
(2005)
Cancer Res
, vol.65
, Issue.14
, pp. 6245-6254
-
-
Capurro, M.I.1
Xiang, Y.Y.2
Lobe, C.3
-
86
-
-
49349103711
-
Glypican-3-mediated oncogenesis involves the Insulin-like growth factorsignaling pathway
-
Cheng W, Tseng CJ, Lin TT, et al. Glypican-3-mediated oncogenesis involves the Insulin-like growth factorsignaling pathway. Carcinogenesis 2008;29(7):1319-26
-
(2008)
Carcinogenesis
, vol.29
, Issue.7
, pp. 1319-1326
-
-
Cheng, W.1
Tseng, C.J.2
Lin, T.T.3
-
87
-
-
78650123226
-
Prognostic significance of circumferential cell surface immunoreactivity of glypican-3 in hepatocellular carcinoma
-
Yorita K, Takahashi N, Takai H, et al. Prognostic significance of circumferential cell surface immunoreactivity of glypican-3 in hepatocellular carcinoma. Liver Int 2011;31(1):120-31
-
(2011)
Liver Int
, vol.31
, Issue.1
, pp. 120-131
-
-
Yorita, K.1
Takahashi, N.2
Takai, H.3
-
88
-
-
78650069449
-
Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization
-
Nakano K, Ishiguro T, Konishi H, et al. Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization. Anticancer Drugs 2010;21(10):907-16
-
(2010)
Anticancer Drugs
, vol.21
, Issue.10
, pp. 907-916
-
-
Nakano, K.1
Ishiguro, T.2
Konishi, H.3
-
89
-
-
57149085273
-
Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer
-
Ishiguro T, Sugimoto M, Kinoshita Y, et al. Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer. Cancer Res 2008;68(23):9832-8
-
(2008)
Cancer Res
, vol.68
, Issue.23
, pp. 9832-9838
-
-
Ishiguro, T.1
Sugimoto, M.2
Kinoshita, Y.3
-
90
-
-
67650474215
-
The expression profile of glypican-3 and its relation to macrophage population in human hepatocellular carcinoma
-
Takai H, Kato A, Kato C, et al. The expression profile of glypican-3 and its relation to macrophage population in human hepatocellular carcinoma. Liver Int 2009;29(7):1056-64
-
(2009)
Liver Int
, vol.29
, Issue.7
, pp. 1056-1064
-
-
Takai, H.1
Kato, A.2
Kato, C.3
-
91
-
-
84908502957
-
Randomized Phase II trial of intravenous RO5137382/GC33 at 1600 mg every other week and placebo in previously treated patients with unresectable advanced hepatocellular carcinoma (HCC; NCT01507168)
-
abstr 4102
-
Yen CJ, Daniele B, Kudo M, et al. Randomized Phase II trial of intravenous RO5137382/GC33 at 1600 mg every other week and placebo in previously treated patients with unresectable advanced hepatocellular carcinoma (HCC; NCT01507168). J Clin Oncol 2014;32(5s):suppl:abstr 4102
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Yen, C.J.1
Daniele, B.2
Kudo, M.3
-
92
-
-
0842325861
-
Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: A method for identifying cancers sensitive to arginine deprivation
-
Dillon BJ, Prieto VG, Curley SA, et al. Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: A method for identifying cancers sensitive to arginine deprivation. Cancer 2004;100(4):826-33
-
(2004)
Cancer
, vol.100
, Issue.4
, pp. 826-833
-
-
Dillon, B.J.1
Prieto, V.G.2
Curley, S.A.3
-
93
-
-
77951903067
-
Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer
-
Delage B, Fennell DA, Nicholson L, et al. Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer. Int J Cancer 2010;126(12):2762-72
-
(2010)
Int J Cancer
, vol.126
, Issue.12
, pp. 2762-2772
-
-
Delage, B.1
Fennell, D.A.2
Nicholson, L.3
-
94
-
-
33846429217
-
Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion
-
Cheng PN, Lam TL, Lam WM, et al. Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion. Cancer Res 2007;67(1):309-17
-
(2007)
Cancer Res
, vol.67
, Issue.1
, pp. 309-317
-
-
Cheng, P.N.1
Lam, T.L.2
Lam, W.M.3
-
95
-
-
79952598775
-
Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis
-
Lam TL, Wong GK, Chow HY, et al. Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis. Pigment Cell Melanoma Res 2011;24(2):366-76
-
(2011)
Pigment Cell Melanoma Res
, vol.24
, Issue.2
, pp. 366-376
-
-
Lam, T.L.1
Wong, G.K.2
Chow, H.Y.3
-
96
-
-
80052271807
-
Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
-
Li M, Zhao H, Zhang X, et al. Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat Genet 2011;43(9):828-9
-
(2011)
Nat Genet
, vol.43
, Issue.9
, pp. 828-829
-
-
Li, M.1
Zhao, H.2
Zhang, X.3
-
97
-
-
84872020299
-
Cancer genome scanning in plasma: Detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
-
Chan KC, Jiang P, Zheng YW, et al. Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing. Clin Chem 2013;59(1):211-24
-
(2013)
Clin Chem
, vol.59
, Issue.1
, pp. 211-224
-
-
Chan, K.C.1
Jiang, P.2
Zheng, Y.W.3
-
98
-
-
84862776817
-
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the Phase III Sorafenib Asia-Pacific trial
-
Cheng AL, Guan Z, Chen Z, et al. Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the Phase III Sorafenib Asia-Pacific trial. Eur J Cancer 2012;48(10):1452-65
-
(2012)
Eur J Cancer
, vol.48
, Issue.10
, pp. 1452-1465
-
-
Cheng, A.L.1
Guan, Z.2
Chen, Z.3
-
99
-
-
84891915708
-
Sunitinib versus sorafenib in advanced hepatocellular cancer: Results of a randomized Phase III trial
-
Cheng AL, Kang YK, Lin DY, et al. Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized Phase III trial. J Clin Oncol 2013;31(32):4067-75
-
(2013)
J Clin Oncol
, vol.31
, Issue.32
, pp. 4067-4075
-
-
Cheng, A.L.1
Kang, Y.K.2
Lin, D.Y.3
|