메뉴 건너뛰기




Volumn 35, Issue 3, 2013, Pages 427-440

Cerebrovascular reactivity to carbon dioxide in alzheimer's disease

Author keywords

Alzheimer's disease; carbon dioxide; cognitive impairment; vascular; vasoreactivity

Indexed keywords

ACETAZOLAMIDE; AMYLOID BETA PROTEIN; CARBON DIOXIDE; CHOLINERGIC RECEPTOR STIMULATING AGENT; ENDOTHELIN 1; MESSENGER RNA; MYOCARDIN; SERUM RESPONSE FACTOR; THROMBIN; XENON 133;

EID: 84880249296     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-122011     Document Type: Review
Times cited : (105)

References (113)
  • 1
    • 66149099232 scopus 로고    scopus 로고
    • Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: Mechanisms of regulation, measurement, and interpretation
    • Anslie PN, Duffin J (2009) Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: Mechanisms of regulation, measurement, and interpretation. Am J Physiol Regul Integr Comp Physiol 296, R1473-R1495.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296
    • Anslie, P.N.1    Duffin, J.2
  • 3
    • 51749106599 scopus 로고    scopus 로고
    • Interaction between the ventilatory and cerebrovascular responses to hypo- and hypercapnia at rest and during exercise
    • Ogoh S, Hayashi N, Inagaki M, Anslie PN, Miyamoto T (2008) Interaction between the ventilatory and cerebrovascular responses to hypo- and hypercapnia at rest and during exercise. J Physiol 586, 4327-4338.
    • (2008) J Physiol , vol.586 , pp. 4327-4338
    • Ogoh, S.1    Hayashi, N.2    Inagaki, M.3    Anslie, P.N.4    Miyamoto, T.5
  • 4
    • 84864781003 scopus 로고    scopus 로고
    • Low residual CBF variability in Alzheimer's disease after correction for CO(2) effect
    • Rodell AB, Aanerud J, Braendgaard H, Gjedde A (2012) Low residual CBF variability in Alzheimer's disease after correction for CO(2) effect. Front Neuroenergetic 4, 8.
    • (2012) Front Neuroenergetic , vol.4 , pp. 8
    • Rodell, A.B.1    Aanerud, J.2    Braendgaard, H.3    Gjedde, A.4
  • 5
    • 19744367632 scopus 로고    scopus 로고
    • Human cerebral circulation: Positron emission tomography studies
    • Ito H, Kanno I, Fukuda H (2005) Human cerebral circulation: Positron emission tomography studies. Ann Nucl Med 19, 65-74.
    • (2005) Ann Nucl Med , vol.19 , pp. 65-74
    • Ito, H.1    Kanno, I.2    Fukuda, H.3
  • 6
    • 33847717428 scopus 로고    scopus 로고
    • Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing
    • Claassen JA, Zhang R, Fu Q, Witkowski S, Levine L, BD (2007) Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing. J Appl Physiol 102, 870-877.
    • (2007) J Appl Physiol , vol.102 , pp. 870-877
    • Claassen, J.A.1    Zhang, R.2    Fu, Q.3    Witkowski, S.4    Levine, L.B.D.5
  • 8
    • 34848909043 scopus 로고    scopus 로고
    • Human cerebrovascular and ventilatory CO2 reactivity to end-tidal, arterial and internal jugular vein PCO2
    • Peebles K, Celi L, McGrattan K, Murrell C, Thomas K, Ainslie PN (2007) Human cerebrovascular and ventilatory CO2 reactivity to end-tidal, arterial and internal jugular vein PCO2. J Physiol 584, 347-357.
    • (2007) J Physiol , vol.584 , pp. 347-357
    • Peebles, K.1    Celi, L.2    McGrattan, K.3    Murrell, C.4    Thomas, K.5    Ainslie, P.N.6
  • 9
    • 0038380275 scopus 로고    scopus 로고
    • Hypercapnic acidosis activates KATP channels in vascular smooth muscles
    • Wang X,Wu J, Li L, Chen F,Wang R, Jiang C (2003) Hypercapnic acidosis activates KATP channels in vascular smooth muscles. Circ Res 92, 1225-1232.
    • (2003) Circ Res , vol.92 , pp. 1225-1232
    • Wang, X.1    Wu, J.2    Li, L.3    Chen, F.4    Wang, R.5    Jiang, C.6
  • 10
    • 0031956920 scopus 로고    scopus 로고
    • Carbon dioxide and the cerebral circulation
    • Brian JE (1998) Carbon dioxide and the cerebral circulation. Anesthesiology 88, 1365-1386.
    • (1998) Anesthesiology , vol.88 , pp. 1365-1386
    • Brian, J.E.1
  • 11
    • 0037446709 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of cerebral blood flow in humans: Chemoregulation versus mechanoregulation
    • Lavi S, Egbarya R, Lavi R, Jacob G (2003) Role of nitric oxide in the regulation of cerebral blood flow in humans: Chemoregulation versus mechanoregulation. Circulation 107, 1901-1905.
    • (2003) Circulation , vol.107 , pp. 1901-1905
    • Lavi, S.1    Egbarya, R.2    Lavi, R.3    Jacob, G.4
  • 12
    • 33749353561 scopus 로고    scopus 로고
    • Impaired cerebral CO2 vasoreactivity: Association with endothelial dysfunction
    • Lavi S, Gaitini D, Milloul V, Jacob G (2006) Impaired cerebral CO2 vasoreactivity: Association with endothelial dysfunction. Am J Physiol Heart Circ Physiol 291, H1856-H1861.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Lavi, S.1    Gaitini, D.2    Milloul, V.3    Jacob, G.4
  • 13
    • 0026446244 scopus 로고
    • Cerebral vasoconstriction in response to hypocapnia is maintained after ischemia/reperfusion injury in newborn pigs
    • Mirro R, Lowery-Smith R, Armstead WR, Shibata M, Zuckerman LS, Leffler CW (1992) Cerebral vasoconstriction in response to hypocapnia is maintained after ischemia/reperfusion injury in newborn pigs. Stroke 23, 1613-1616.
    • (1992) Stroke , vol.23 , pp. 1613-1616
    • Mirro, R.1    Lowery-Smith, R.2    Armstead, W.R.3    Shibata, M.4    Zuckerman, L.S.5    Leffler, C.W.6
  • 14
    • 72749126062 scopus 로고    scopus 로고
    • Cerebral blood flow during exercise: Mechanisms of regulation
    • Ogoh S, Anslie PN (2009) Cerebral blood flow during exercise: Mechanisms of regulation. J Appl Physiol 107, 1370-1380.
    • (2009) J Appl Physiol , vol.107 , pp. 1370-1380
    • Ogoh, S.1    Anslie, P.N.2
  • 15
    • 33751016765 scopus 로고    scopus 로고
    • Global cerebral blood flow in relation to cognitive performance and reserve in subjects with mild memory deficits
    • Boles Ponto LL, MagnottaVA,Moser DJ, Duff KM, Schultz SK (2006) Global cerebral blood flow in relation to cognitive performance and reserve in subjects with mild memory deficits. Mol Imaging Biol 8, 363-372.
    • (2006) Mol Imaging Biol , vol.8 , pp. 363-372
    • Boles Ponto, L.L.1    Magnotta, V.A.2    Moser, D.J.3    Duff, K.M.4    Schultz, S.K.5
  • 16
    • 0024565352 scopus 로고
    • SPECT study of cerebral blood flow reactivity after acetazolamide in patients with transient ischemic attacks
    • Chollet F, Celsis P, Clanet M, Guirard-Chaumeil B, Rascol A, Marc-Vergnes JP (1989) SPECT study of cerebral blood flow reactivity after acetazolamide in patients with transient ischemic attacks. Stroke 20, 458-464.
    • (1989) Stroke , vol.20 , pp. 458-464
    • Chollet, F.1    Celsis, P.2    Clanet, M.3    Guirard-Chaumeil, B.4    Rascol, A.5    Marc-Vergnes, J.P.6
  • 18
    • 79551616004 scopus 로고    scopus 로고
    • Effects of physiological aging and cerebrovascular risk factors on the hemodynamic response to brain activation: A functional transcranial doppler study
    • Groschel K, Terborg C, Riecker A, Witte OW, Kastrup A (2007) Effects of physiological aging and cerebrovascular risk factors on the hemodynamic response to brain activation: A functional transcranial doppler study. Clin Neurophysiol 118, e35-e36.
    • (2007) Clin Neurophysiol , vol.118
    • Groschel, K.1    Terborg, C.2    Riecker, A.3    Witte, O.W.4    Kastrup, A.5
  • 19
    • 0345074108 scopus 로고    scopus 로고
    • Cerebrovascular reactivity in hypertensive and healthy adolescents: TCD With vasodilatory challenge
    • Settakis G, Pall D, Molnar C, Bereczki D, Csiba L, Fulesdi B (2003) Cerebrovascular reactivity in hypertensive and healthy adolescents: TCD With vasodilatory challenge. J Neuroimaging 13, 106-112.
    • (2003) J Neuroimaging , vol.13 , pp. 106-112
    • Settakis, G.1    Pall, D.2    Molnar, C.3    Bereczki, D.4    Csiba, L.5    Fulesdi, B.6
  • 21
    • 79959835757 scopus 로고    scopus 로고
    • Cerebral autoregulation in Alzheimer's disease
    • Claassen JA, Zhang R (2011) Cerebral autoregulation in Alzheimer's disease. J Cereb Blood Flow Metab 31, 1572-1577.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1572-1577
    • Claassen, J.A.1    Zhang, R.2
  • 22
    • 60949108829 scopus 로고    scopus 로고
    • Blood pressure and the risk for dementia - A double edged sword
    • Kennelly SA, Lawlor B, Kenny RA (2009) Blood pressure and the risk for dementia - A double edged sword. Aging Res Rev 8, 61-70.
    • (2009) Aging Res Rev , vol.8 , pp. 61-70
    • Kennelly, S.A.1    Lawlor, B.2    Kenny, R.A.3
  • 24
    • 25144454460 scopus 로고    scopus 로고
    • Brain white matter hyperintensities: Relative importance of vascular risk factors in nondemented elderly people
    • Murray AD, Staff RT, Shenkin SD, Deary IJ, Starr JM, Whalley LJ (2005) Brain white matter hyperintensities: Relative importance of vascular risk factors in nondemented elderly people. Radiology 237, 251-257.
    • (2005) Radiology , vol.237 , pp. 251-257
    • Murray, A.D.1    Staff, R.T.2    Shenkin, S.D.3    Deary, I.J.4    Starr, J.M.5    Whalley, L.J.6
  • 26
    • 79251507618 scopus 로고    scopus 로고
    • The effects of dietary and nutrient interventions on arterial stiffness: A systematic review
    • Pase MP, Grima NA, Sarris J (2011) The effects of dietary and nutrient interventions on arterial stiffness: A systematic review. Am J Clin Nutr 93, 446-454.
    • (2011) Am J Clin Nutr , vol.93 , pp. 446-454
    • Pase, M.P.1    Grima, N.A.2    Sarris, J.3
  • 27
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer's disease
    • Iadecola C (2004) Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci 5, 347-360.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 347-360
    • Iadecola, C.1
  • 28
    • 66249137528 scopus 로고    scopus 로고
    • Carotid artery ultrasound and echocardiography testing to lower the prevalence of Alzheimer's disease
    • de la Torre JC (2009) Carotid artery ultrasound and echocardiography testing to lower the prevalence of Alzheimer's disease. J Stroke Cerebrovasc Dis 18, 319-328.
    • (2009) J Stroke Cerebrovasc Dis , vol.18 , pp. 319-328
    • De La Torre, J.C.1
  • 29
    • 0035047718 scopus 로고    scopus 로고
    • Cerebral microvascular pathology in aging and Alzheimer's disease
    • Farkas E, Luiten PGM (2001) Cerebral microvascular pathology in aging and Alzheimer's disease. Pro Neurobiol 64, 575-611.
    • (2001) Pro Neurobiol , vol.64 , pp. 575-611
    • Farkas, E.1    Luiten, P.G.M.2
  • 30
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic BV (2011) Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 12, 723-738.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 32
    • 0031447383 scopus 로고    scopus 로고
    • Psychometric properties and factor structure of the Wechsler Memory Scale-Revised in a sample of persons with intractable epilepsy
    • Moore PM, Baker GA (1997) Psychometric properties and factor structure of the Wechsler Memory Scale-Revised in a sample of persons with intractable epilepsy. J Clin Exp Neuropsychol 19, 897-905.
    • (1997) J Clin Exp Neuropsychol , vol.19 , pp. 897-905
    • Moore, P.M.1    Baker, G.A.2
  • 33
    • 0031951913 scopus 로고    scopus 로고
    • Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men
    • Kilander L, Nyman H, Boberg M, Hansson L, Lithell H (1998) Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men. Hypertension 31, 780-786.
    • (1998) Hypertension , vol.31 , pp. 780-786
    • Kilander, L.1    Nyman, H.2    Boberg, M.3    Hansson, L.4    Lithell, H.5
  • 35
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft S, Watson GS (2004) Insulin and neurodegenerative disease: Shared and specific mechanisms. Lancet Neurol 3, 169-178.
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 37
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82, 239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 38
    • 0029670094 scopus 로고    scopus 로고
    • Beta]-Amyloid-mediated vasoactivity and vascular endothelial damage
    • Thomas T, Thomas G, McLendon C, Sutton T, Mullan M (1996) [beta]-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature 380, 168-171.
    • (1996) Nature , vol.380 , pp. 168-171
    • Thomas, T.1    Thomas, G.2    McLendon, C.3    Sutton, T.4    Mullan, M.5
  • 39
    • 0032032969 scopus 로고    scopus 로고
    • Characteristics of the in vitro vasoactivity of beta-amyloid peptides
    • Crawford F, Suo Z, Fang C, MullanM(1998) Characteristics of the in vitro vasoactivity of beta-amyloid peptides. Exp Neurol 150, 159-168.
    • (1998) Exp Neurol , vol.150 , pp. 159-168
    • Crawford, F.1    Suo, Z.2    Fang, C.3    Mullan, M.4
  • 40
    • 0032431592 scopus 로고    scopus 로고
    • Enhancement of systemic and pulmonary vasoconstriction by beta-amyloid peptides and its suppression by vasoactive intestinal peptide
    • Said SI, Raza S, Berisha HI (1998) Enhancement of systemic and pulmonary vasoconstriction by beta-amyloid peptides and its suppression by vasoactive intestinal peptide. Ann N Y Acad Sci 865, 582-585.
    • (1998) Ann N Y Acad Sci , vol.865 , pp. 582-585
    • Said, S.I.1    Raza, S.2    Berisha, H.I.3
  • 41
    • 0030583638 scopus 로고    scopus 로고
    • Mechanisms underlying the vascular activity of [beta]-amyloid protein fragment ([beta]A425-35) at the level of skin microvasculature
    • Khalil Z, Chen HB, HelmeRD(1996) Mechanisms underlying the vascular activity of [beta]-amyloid protein fragment ([beta]A425-35) at the level of skin microvasculature. Brain Res 736, 206-216.
    • (1996) Brain Res , vol.736 , pp. 206-216
    • Khalil, Z.1    Chen, H.B.2    Helme, R.D.3
  • 44
    • 0036176504 scopus 로고    scopus 로고
    • Alterations in cerebral blood flowand glucose utilization in mice overexpressing the amyloid precursor protein
    • Niwa K, Kazama K, Younkin SG, Carlson GA, Idecola C (2002) Alterations in cerebral blood flowand glucose utilization in mice overexpressing the amyloid precursor protein. Neurobiol Dis 9, 61-68.
    • (2002) Neurobiol Dis , vol.9 , pp. 61-68
    • Niwa, K.1    Kazama, K.2    Younkin, S.G.3    Carlson, G.A.4    Idecola, C.5
  • 46
    • 84860165011 scopus 로고    scopus 로고
    • Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-beta
    • Palmer JC, Barker R, Kehoe PG, Love S (2012) Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-beta. J Alzheimers Dis 29, 853-861.
    • (2012) J Alzheimers Dis , vol.29 , pp. 853-861
    • Palmer, J.C.1    Barker, R.2    Kehoe, P.G.3    Love, S.4
  • 48
    • 0035816707 scopus 로고    scopus 로고
    • Degradation of the Alzheimer's amyloid beta peptide by endothelinconverting enzyme
    • Eckman EA, Reed DK, Eckman CB (2001) Degradation of the Alzheimer's amyloid beta peptide by endothelinconverting enzyme. J Biol Chem 276, 24540-24548.
    • (2001) J Biol Chem , vol.276 , pp. 24540-24548
    • Eckman, E.A.1    Reed, D.K.2    Eckman, C.B.3
  • 49
    • 67649984550 scopus 로고    scopus 로고
    • Endothelinconverting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta
    • Palmer JC, Baig S, Kehoe PG, Love S (2009) Endothelinconverting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta. Am J Pathol 175, 262-270.
    • (2009) Am J Pathol , vol.175 , pp. 262-270
    • Palmer, J.C.1    Baig, S.2    Kehoe, P.G.3    Love, S.4
  • 50
    • 77957271001 scopus 로고    scopus 로고
    • Endothelin1 is elevated in Alzheimer's disease brain microvessels and is neuroprotective
    • Luo J, Grammas P (2010) Endothelin1 is elevated in Alzheimer's disease brain microvessels and is neuroprotective. J Alzheimers Dis 21, 887-896.
    • (2010) J Alzheimers Dis , vol.21 , pp. 887-896
    • Luo, J.1    Grammas, P.2
  • 51
    • 79957451034 scopus 로고    scopus 로고
    • Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration
    • Madonna R, De Caterina R, Willerson JT, Geng YJ (2011) Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration. Eur Heart J 32, 1190-1196.
    • (2011) Eur Heart J , vol.32 , pp. 1190-1196
    • Madonna, R.1    De Caterina, R.2    Willerson, J.T.3    Geng, Y.J.4
  • 54
    • 33847725166 scopus 로고    scopus 로고
    • The roles of proteinase-activated receptors in the vascular physiology and pathophysiology
    • Hirano K (2007) The roles of proteinase-activated receptors in the vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 27, 27-36.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 27-36
    • Hirano, K.1
  • 55
    • 78349253052 scopus 로고    scopus 로고
    • Current perspective on the role of the thrombin receptor in cerebral vasospasm after subarachnoid hemorrhage
    • Hirano K, Hirano M (2010) Current perspective on the role of the thrombin receptor in cerebral vasospasm after subarachnoid hemorrhage. J Pharmacol Sci 114, 127-133.
    • (2010) J Pharmacol Sci , vol.114 , pp. 127-133
    • Hirano, K.1    Hirano, M.2
  • 56
    • 78649890216 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in thrombin-induced pulmonary vasoconstriction
    • Maki J, Hirano M, Hoka S, Kanaide H, Hirano K (2010) Involvement of reactive oxygen species in thrombin-induced pulmonary vasoconstriction. Am J Respir Crit Care Med 182, 1435-1444.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1435-1444
    • Maki, J.1    Hirano, M.2    Hoka, S.3    Kanaide, H.4    Hirano, K.5
  • 57
    • 33644905917 scopus 로고    scopus 로고
    • Thrombin and prothrombin are expressed by neurons and glial cells and accumulate in neurofibrillary tangles in Alzheimer disease brain
    • Arai T, Miklossy J, Klegeris A, Guo JP, McGeer PL (2006) Thrombin and prothrombin are expressed by neurons and glial cells and accumulate in neurofibrillary tangles in Alzheimer disease brain. J Neuropathol Exp Neurol 65, 19-25.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 19-25
    • Arai, T.1    Miklossy, J.2    Klegeris, A.3    Guo, J.P.4    McGeer, P.L.5
  • 58
    • 5644248024 scopus 로고    scopus 로고
    • Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial
    • EngelbergH(2004) Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial. Dement Geriatr Cogn Disord 18, 278-298.
    • (2004) Dement Geriatr Cogn Disord , vol.18 , pp. 278-298
    • Engelberg, H.1
  • 60
    • 33646014454 scopus 로고    scopus 로고
    • Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: Implications for disease pathogenesis
    • Grammas P, Samany PG, Thirumangalakudi L (2006) Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: Implications for disease pathogenesis. J Alzheimers Dis 9, 51-58.
    • (2006) J Alzheimers Dis , vol.9 , pp. 51-58
    • Grammas, P.1    Samany, P.G.2    Thirumangalakudi, L.3
  • 61
    • 77950560732 scopus 로고    scopus 로고
    • Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease
    • YinX, right J, allT, Rammas P (2010) Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease. Am J Pathol 176, 1600-1606.
    • (2010) Am J Pathol , vol.176 , pp. 1600-1606
    • Yin, X.1    Right, J.2    All, T.3    Rammas, P.4
  • 62
    • 33646009985 scopus 로고    scopus 로고
    • Cholinergically mediated augmentation of cerebral perfusion in Alzheimer's disease and related cognitive disorders: The cholinergic-vascular hypothesis
    • Claassen JA, Jansen RW (2006) Cholinergically mediated augmentation of cerebral perfusion in Alzheimer's disease and related cognitive disorders: The cholinergic-vascular hypothesis. J Gerontol A Biol Sci Med Sci 61, 267-271.
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , pp. 267-271
    • Claassen, J.A.1    Jansen, R.W.2
  • 63
    • 79955735314 scopus 로고    scopus 로고
    • The cerebrovascular role of the cholinergic neural system in Alzheimer's disease
    • van Beek AH, Claassen JA (2011) The cerebrovascular role of the cholinergic neural system in Alzheimer's disease. Behav Brain Res 221, 537-542.
    • (2011) Behav Brain Res , vol.221 , pp. 537-542
    • Van Beek, A.H.1    Claassen, J.A.2
  • 64
    • 0037186455 scopus 로고    scopus 로고
    • Regulation of cerebral cortical blood flow by the basal forebrain cholinergic fibers and aging
    • Sato A, Sato Y, Uchida S (2002) Regulation of cerebral cortical blood flow by the basal forebrain cholinergic fibers and aging. Auton Neurosci 96, 13-19.
    • (2002) Auton Neurosci , vol.96 , pp. 13-19
    • Sato, A.1    Sato, Y.2    Uchida, S.3
  • 65
    • 0028800951 scopus 로고
    • Cholinergic basal forebrain neurons project to cortical microvessels in the rat: Electron microscopic study with anterogradely transported Phaseolus vulgaris leucoagglutinin and choline acetyltransferase immunocytochemistry
    • Vaucher E, Hamel E (1995) Cholinergic basal forebrain neurons project to cortical microvessels in the rat: Electron microscopic study with anterogradely transported Phaseolus vulgaris leucoagglutinin and choline acetyltransferase immunocytochemistry. J Neurosci 15, 7427-7441.
    • (1995) J Neurosci , vol.15 , pp. 7427-7441
    • Vaucher, E.1    Hamel, E.2
  • 66
    • 0033821478 scopus 로고    scopus 로고
    • Basal forebrain nitric oxide synthase (NOS)-containing neurons project to microvessels and NOS neurons in the rat neocortex: Cellular basis for cortical blood flow regulation
    • Tong XK, Hamel E (2000) Basal forebrain nitric oxide synthase (NOS)-containing neurons project to microvessels and NOS neurons in the rat neocortex: Cellular basis for cortical blood flow regulation. Eur J Neurosci 12, 2769-2780.
    • (2000) Eur J Neurosci , vol.12 , pp. 2769-2780
    • Tong, X.K.1    Hamel, E.2
  • 67
    • 63149112031 scopus 로고    scopus 로고
    • Cerebral cortical vasodilatation mediated by nicotinic cholinergic receptors: Effects of old age and of chronic nicotine exposure
    • Uchida S, Hotta H (2009) Cerebral cortical vasodilatation mediated by nicotinic cholinergic receptors: Effects of old age and of chronic nicotine exposure. Biol Pharm Bull 32, 341-344.
    • (2009) Biol Pharm Bull , vol.32 , pp. 341-344
    • Uchida, S.1    Hotta, H.2
  • 68
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies P, Maloney AJF (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2, 1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.F.2
  • 69
    • 79954582437 scopus 로고    scopus 로고
    • Revisiting the cholinergic hypothesis in the development of Alzheimer's disease
    • Craig LA, Hong NS, McDonald RJ (2011) Revisiting the cholinergic hypothesis in the development of Alzheimer's disease. Neurosci Biobehav Rev 35, 1397-1409.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1397-1409
    • Craig, L.A.1    Hong, N.S.2    McDonald, R.J.3
  • 70
    • 0242523117 scopus 로고    scopus 로고
    • The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia
    • Lojkowska W, Ryglewicz D, Jedrzejczak T, Minc S, Jakubowska T, Jarosz H, Bochynska A (2003) The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia. J Neurol Sci 216, 119-126.
    • (2003) J Neurol Sci , vol.216 , pp. 119-126
    • Lojkowska, W.1    Ryglewicz, D.2    Jedrzejczak, T.3    Minc, S.4    Jakubowska, T.5    Jarosz, H.6    Bochynska, A.7
  • 71
    • 84862777777 scopus 로고    scopus 로고
    • Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment
    • Li W, Antuono PG, Xie C, Chen G, Jones JL, Ward BD, Franczak MB, Goveas JS, Li SJ (2012) Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment. Neuroimage 60, 1083-1091.
    • (2012) Neuroimage , vol.60 , pp. 1083-1091
    • Li, W.1    Antuono, P.G.2    Xie, C.3    Chen, G.4    Jones, J.L.5    Ward, B.D.6    Franczak, M.B.7    Goveas, J.S.8    Li, S.J.9
  • 72
    • 50249167175 scopus 로고    scopus 로고
    • The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia
    • Imamura K, Wada-Isoe K, Kowa H, Tanabe Y, Nakashima K (2008) The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia. Neurocase 14, 271-275.
    • (2008) Neurocase , vol.14 , pp. 271-275
    • Imamura, K.1    Wada-Isoe, K.2    Kowa, H.3    Tanabe, Y.4    Nakashima, K.5
  • 77
    • 0032938078 scopus 로고    scopus 로고
    • The effects of scopolamine on changes in regional cerebral blood flow during classical conditioning of the human eyeblink response
    • Bahro M, Molchan SE, Sunderland T, Herscovitch P, Schreurs BG (1999) The effects of scopolamine on changes in regional cerebral blood flow during classical conditioning of the human eyeblink response. Neuropsychobiology 39, 187-195.
    • (1999) Neuropsychobiology , vol.39 , pp. 187-195
    • Bahro, M.1    Molchan, S.E.2    Sunderland, T.3    Herscovitch, P.4    Schreurs, B.G.5
  • 78
    • 36448974220 scopus 로고    scopus 로고
    • Influence of galantamine on vasomotor reactivity in Alzheimer's disease and vascular dementia due to cerebral microangiopathy
    • Bar KJ, Boettger MK, Seidler N, Mentzel HJ, Terborg C, SauerH(2007) Influence of galantamine on vasomotor reactivity in Alzheimer's disease and vascular dementia due to cerebral microangiopathy. Stroke 38, 3186-3192.
    • (2007) Stroke , vol.38 , pp. 3186-3192
    • Bar, K.J.1    Boettger, M.K.2    Seidler, N.3    Mentzel, H.J.4    Terborg, C.5    Sauer, H.6
  • 79
    • 84875655895 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature
    • Wyss-Coray T, Rogers J (2012) Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med 2, a006346.
    • (2012) Cold Spring Harb Perspect Med , vol.2
    • Wyss-Coray, T.1    Rogers, J.2
  • 80
    • 47849100075 scopus 로고    scopus 로고
    • Alzheimer's disease and peripheral infections: The possible contribution from periodontal infections, model and hypothesis
    • Kamer AR, Dasanayake AP, Craig RG, Glodzik-Sobanska L, Brys M, de Leon MJ (2008) Alzheimer's disease and peripheral infections: The possible contribution from periodontal infections, model and hypothesis. J Alzheimers Dis 13, 437-449.
    • (2008) J Alzheimers Dis , vol.13 , pp. 437-449
    • Kamer, A.R.1    Dasanayake, A.P.2    Craig, R.G.3    Glodzik-Sobanska, L.4    Brys, M.5    De Leon, M.J.6
  • 84
    • 0024375061 scopus 로고
    • Alzheimer's disease as a capillary dementia
    • Scheibel AB, Duong T, JacobsR(1989) Alzheimer's disease as a capillary dementia. Ann Med 21, 103-107.
    • (1989) Ann Med , vol.21 , pp. 103-107
    • Scheibel, A.B.1    Duong T, JacobsR.2
  • 85
    • 33745029547 scopus 로고    scopus 로고
    • Prevalence and impact of cerebrovascular pathology in Alzheimer's disease and parkinsonism
    • Jellinger KA, Attems J (2006) Prevalence and impact of cerebrovascular pathology in Alzheimer's disease and parkinsonism. Acta Neurol Scand 114, 38-46.
    • (2006) Acta Neurol Scand , vol.114 , pp. 38-46
    • Jellinger, K.A.1    Attems, J.2
  • 87
    • 0025933618 scopus 로고
    • Morphological changes of blood vessels in the brain with Alzheimer's disease
    • Hashimura T, Kimura T, Miyakawa T (1991) Morphological changes of blood vessels in the brain with Alzheimer's disease. Jpn J Psychiatry Neurol 45, 661-665.
    • (1991) Jpn J Psychiatry Neurol , vol.45 , pp. 661-665
    • Hashimura, T.1    Kimura, T.2    Miyakawa, T.3
  • 88
    • 0030721487 scopus 로고    scopus 로고
    • Brain microvascular changes in Alzheimer's disease and other dementias
    • Buee L, Hof PR, Delacourte A (1997) Brain microvascular changes in Alzheimer's disease and other dementias. Ann N Y Acad Sci 826, 7-24.
    • (1997) Ann N Y Acad Sci , vol.826 , pp. 7-24
    • Buee, L.1    Hof, P.R.2    Delacourte, A.3
  • 89
  • 91
    • 0018870064 scopus 로고
    • Noninvasive regional cerebral blood flow measurements in dementia
    • Yamaguchi F, Meyer JS, Yamamoto M, Sakai F, Shaw T (1980) Noninvasive regional cerebral blood flow measurements in dementia. Arch Neurol 37, 410-418.
    • (1980) Arch Neurol , vol.37 , pp. 410-418
    • Yamaguchi, F.1    Meyer, J.S.2    Yamamoto, M.3    Sakai, F.4    Shaw, T.5
  • 92
    • 0024520258 scopus 로고
    • The effect of acetazolamide on regional cerebral blood flow in patients with Alzheimer's disease or stroke as measured by single-photon emission computed tomography
    • Bonte FJ, Devous MD Sr., Reisch JS, Ajmani AK, Weiner MF, Hom J, Tintner R (1989) The effect of acetazolamide on regional cerebral blood flow in patients with Alzheimer's disease or stroke as measured by single-photon emission computed tomography. Invest Radiol 24, 99-103.
    • (1989) Invest Radiol , vol.24 , pp. 99-103
    • Bonte, F.J.1    Devous Sr., M.D.2    Reisch, J.S.3    Ajmani, A.K.4    Weiner, M.F.5    Hom, J.6    Tintner, R.7
  • 93
    • 0028933502 scopus 로고
    • Cerebrovascular reactivity to acetazolamide in (senile) dementia of Alzheimer's type: Relationship to disease severity
    • Stoppe G, Schultze R, Kogler A, Staedt J, Munz DL, Emrich D, Ruther E (1995) Cerebrovascular reactivity to acetazolamide in (senile) dementia of Alzheimer's type: Relationship to disease severity. Dementia 6, 73-82.
    • (1995) Dementia , vol.6 , pp. 73-82
    • Stoppe, G.1    Schultze, R.2    Kogler, A.3    Staedt, J.4    Munz, D.L.5    Emrich, D.6    Ruther, E.7
  • 96
    • 7944238069 scopus 로고    scopus 로고
    • Regional differences in cerebrovascular reactivity to acetazolamide in Alzheimer's disease
    • Oishi M, Mochizuki Y, Takasu T (1999) Regional differences in cerebrovascular reactivity to acetazolamide in Alzheimer's disease. J Clin Neurosci 6, 380-381.
    • (1999) J Clin Neurosci , vol.6 , pp. 380-381
    • Oishi, M.1    Mochizuki, Y.2    Takasu, T.3
  • 97
    • 0021084822 scopus 로고
    • Brain blood flow measured with intravenous 0-15H2O. 2. Implementation and validation
    • Raichle ME, Martin WRW, Herscovitch P, Mintum MA, Markham J (1983) Brain blood flow measured with intravenous 0-15H2O. 2. Implementation and validation. J Nucl Med 24, 790-798.
    • (1983) J Nucl Med , vol.24 , pp. 790-798
    • Raichle, M.E.1    Martin, W.R.W.2    Herscovitch, P.3    Mintum, M.A.4    Markham, J.5
  • 98
    • 0021030757 scopus 로고    scopus 로고
    • Brain blood flow measured with intravenous H2O15. I. Theory and error analysis
    • Herscovitch P, Markham J, Raichle ME (2013) Brain blood flow measured with intravenous H2O15. I. Theory and error analysis. J Nucl Med 24, 782-789.
    • (2013) J Nucl Med , vol.24 , pp. 782-789
    • Herscovitch, P.1    Markham, J.2    Raichle, M.E.3
  • 99
    • 0026561073 scopus 로고
    • Cerebrovascular responsiveness to hypercapnia in Alzheimer's dementia and vascular dementia of the Binswanger type
    • Kuwabara Y, Ichiya Y, Otsuka M, Masuda K, Ichimiya A, Fujishima M (1992) Cerebrovascular responsiveness to hypercapnia in Alzheimer's dementia and vascular dementia of the Binswanger type. Stroke 23, 594-598.
    • (1992) Stroke , vol.23 , pp. 594-598
    • Kuwabara, Y.1    Ichiya, Y.2    Otsuka, M.3    Masuda, K.4    Ichimiya, A.5    Fujishima, M.6
  • 101
    • 0014040424 scopus 로고
    • Effect of contrast material, hypercapnia, hyperventilation, hypertonic glucose and papaverine on the diameter of the cerebral arteries. Angiographic determination in man
    • Huber P, Handa J (1967) Effect of contrast material, hypercapnia, hyperventilation, hypertonic glucose and papaverine on the diameter of the cerebral arteries. Angiographic determination in man. Invest Radiol 2, 17-32.
    • (1967) Invest Radiol , vol.2 , pp. 17-32
    • Huber, P.1    Handa, J.2
  • 102
    • 0037382001 scopus 로고    scopus 로고
    • The emperor has no clothes: Velocity, flow, and the use of TCD
    • GillerCA(2003) The emperor has no clothes: Velocity, flow, and the use of TCD. J Neuroimag 13, 97-98.
    • (2003) J Neuroimag , vol.13 , pp. 97-98
    • Giller, C.A.1
  • 104
    • 67650118648 scopus 로고    scopus 로고
    • Vasoreactivity induced by acetazolamide in patients with vascular dementia versus Alzheimer's disease
    • Likitjaroen Y, Suwanwela NC, Phanthumchinda K (2009) Vasoreactivity induced by acetazolamide in patients with vascular dementia versus Alzheimer's disease. J Neurol Sci 283, 32-35.
    • (2009) J Neurol Sci , vol.283 , pp. 32-35
    • Likitjaroen, Y.1    Suwanwela, N.C.2    Phanthumchinda, K.3
  • 112
    • 0345446720 scopus 로고    scopus 로고
    • Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging
    • Rusinek H, De Santi S, Frid D, Tsui W, Tarshish C, Convit A, de Leon MJ (2003) Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging. Radiology 229, 691-696.
    • (2003) Radiology , vol.229 , pp. 691-696
    • Rusinek, H.1    De Santi, S.2    Frid, D.3    Tsui, W.4    Tarshish, C.5    Convit, A.6    De Leon, M.J.7
  • 113
    • 0028985629 scopus 로고
    • Low CO2 stimulates inositol phosphate turnover and increased inositol 1,4,5-trisphosphate levels in piglet cerebral microvascular smooth muscle cells
    • Albuquerque ML, Lowery-Smith L, Hsu P, Parfenova H, Leffler CW (1995) Low CO2 stimulates inositol phosphate turnover and increased inositol 1,4,5-trisphosphate levels in piglet cerebral microvascular smooth muscle cells. Proc Soc Exp Biol Med 209, 14-19.
    • (1995) Proc Soc Exp Biol Med , vol.209 , pp. 14-19
    • Albuquerque, M.L.1    Lowery-Smith, L.2    Hsu, P.3    Parfenova, H.4    Leffler, C.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.