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Volumn 2, Issue 3, 2010, Pages

Should the ApoE genotype be a covariate for clinical trials in Alzheimer disease?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; BAPINEUZUMAB; CARRIER PROTEIN; DONEPEZIL; GALANTAMINE; LIPID; PLACEBO; RIVASTIGMINE; ROSIGLITAZONE; TACRINE;

EID: 81755170928     PISSN: None     EISSN: 17589193     Source Type: Journal    
DOI: 10.1186/alzrt39     Document Type: Review
Times cited : (14)

References (15)
  • 1
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    • Apolipoprotein E-episilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • 8669492
    • Apolipoprotein E-episilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN, Am J Pathol 1996 148 2083 2095 8669492
    • (1996) Am J Pathol , vol.148 , pp. 2083-2095
    • Premkumar, D.R.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 2
    • 0031664361 scopus 로고    scopus 로고
    • High frequency of apolipoprotein E ε4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes
    • DOI 10.1006/exnr.1998.6860
    • High frequency of apolipoprotein E epsilo4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Ghebremedhin E, Schultz C, Braak E, Braak H, Exp Neurol 1998 153 152 155 (Pubitemid 28452307)
    • (1998) Experimental Neurology , vol.153 , Issue.1 , pp. 152-155
    • Ghebremedhin, E.1    Schultz, C.2    Braak, E.3    Braak, H.4
  • 7
    • 0031831690 scopus 로고    scopus 로고
    • Microglial activation in Alzheimer disease: Association with APOE genotype
    • Microglial activation in Alzheimer disease: association with APOE genotype. Egensperger R, Kosel S, von Eitzen U, Graeber MB, Brain Pathol 1998 8 439 447 (Pubitemid 28308843)
    • (1998) Brain Pathology , vol.8 , Issue.3 , pp. 439-447
    • Egensperger, R.1    Kosel, S.2    Von Eitzen, U.3    Graeber, M.B.4
  • 9
    • 0036021007 scopus 로고    scopus 로고
    • Presence or absence of at least one ε4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease
    • DOI 10.1097/00008571-200207000-00009
    • Presence or absence of at least one e4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease. Rigaud A-S, Traykov L, Latour F, Couderc R, Moulin F, Forette F, Pharmacogenetics 2002 12 415 420 10.1097/00008571-200207000-00009 (Pubitemid 34816421)
    • (2002) Pharmacogenetics , vol.12 , Issue.5 , pp. 415-420
    • Rigaud, A.-S.1    Traykov, L.2    Latour, F.3    Couderc, R.4    Moulin, F.5    Forette, F.6
  • 11
    • 0035130170 scopus 로고    scopus 로고
    • APOE genotype: No influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease
    • DOI 10.1159/000051238
    • APOE genotype: no influence on galantamine treatment efficacy or on rate of decline in Alzheimer's disease. Aerssens J, Raeymaekers P, Lilienfeld S, Geerts H, Konings F, Parys W, Dement Geriatr Cogn Disord 2001 12 69 77 10.1159/000051238 11173877 (Pubitemid 32149710)
    • (2001) Dementia and Geriatric Cognitive Disorders , vol.12 , Issue.2 , pp. 69-77
    • Aerssens, J.1    Raeymaekers, P.2    Lilienfeld, S.3    Geerts, H.4    Konings, F.5    Parys, W.6
  • 12
    • 57649131090 scopus 로고    scopus 로고
    • The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5791 as a model of safety
    • 10.1038/npp.2008.153 18923406
    • The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5791 as a model of safety. Roses AD, Neuropsychopharmacology 2009 34 6 17 10.1038/npp.2008.153 18923406
    • (2009) Neuropsychopharmacology , vol.34 , pp. 6-17
    • Roses, A.D.1
  • 13
    • 84891830122 scopus 로고    scopus 로고
    • Alzforum http://www.alzforum.org/drg/drc/detail.asp?id=116
    • Drugs in Clinical Trials-Rosiglitazone. Alzforum, http://www.alzforum. org/drg/drc/detail.asp?id=116
    • Drugs in Clinical Trials - Rosiglitazone


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.