-
1
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
JT Mendell, and EN Olson MicroRNAs in stress signaling and human disease Cell 148 2012 1172 1187
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
2
-
-
84899658554
-
MicroRNAs in cardiovascular diseases: Current knowledge and the road ahead
-
G Condorelli, MV Latronico, and E Cavarretta microRNAs in cardiovascular diseases: current knowledge and the road ahead J Am Coll Cardiol 63 2014 2177 2187
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2177-2187
-
-
Condorelli, G.1
Latronico, M.V.2
Cavarretta, E.3
-
3
-
-
84873817376
-
MicroRNAs in cardiovascular disease: From pathogenesis to prevention and treatment
-
D Quiat, and EN Olson MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment J Clin Invest 123 2013 11 18
-
(2013)
J Clin Invest
, vol.123
, pp. 11-18
-
-
Quiat, D.1
Olson, E.N.2
-
4
-
-
84910080839
-
The emerging role of microRNAs in cardiovascular disease
-
L Maegdefessel The emerging role of microRNAs in cardiovascular disease J Intern Med 276 2014 633 644
-
(2014)
J Intern Med
, vol.276
, pp. 633-644
-
-
Maegdefessel, L.1
-
5
-
-
51349141401
-
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
-
E van Rooij, LB Sutherland, JE Thatcher, JM DiMaio, RH Naseem, and WS Marshall Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis Proc Natl Acad Sci U S A 105 2008 13027 13032
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13027-13032
-
-
Van Rooij, E.1
Sutherland, L.B.2
Thatcher, J.E.3
Dimaio, J.M.4
Naseem, R.H.5
Marshall, W.S.6
-
6
-
-
44349191959
-
Everything you wanted to know about small RNA but were afraid to ask
-
SD Boyd Everything you wanted to know about small RNA but were afraid to ask Lab Invest 88 2008 569 578
-
(2008)
Lab Invest
, vol.88
, pp. 569-578
-
-
Boyd, S.D.1
-
7
-
-
84922422451
-
In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA
-
G La Rocca, SH Olejniczak, AJ Gonzalez, D Briskin, JA Vidigal, and L Spraggon In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA Proc Natl Acad Sci U S A 112 2015 767 772
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 767-772
-
-
La Rocca, G.1
Olejniczak, S.H.2
Gonzalez, A.J.3
Briskin, D.4
Vidigal, J.A.5
Spraggon, L.6
-
8
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
DP Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
9
-
-
84925883377
-
MiRWalk database for miRNA-target interactions
-
H Dweep, N Gretz, and C Sticht miRWalk database for miRNA-target interactions Methods Mol Biol 1182 2014 289 305
-
(2014)
Methods Mol Biol
, vol.1182
, pp. 289-305
-
-
Dweep, H.1
Gretz, N.2
Sticht, C.3
-
10
-
-
84891818318
-
MiRBase: Annotating high confidence microRNAs using deep sequencing data
-
A Kozomara, and S Griffiths-Jones miRBase: annotating high confidence microRNAs using deep sequencing data Nucleic Acids Res 42 2014 D68 D73
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D68-D73
-
-
Kozomara, A.1
Griffiths-Jones, S.2
-
11
-
-
84924388328
-
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs
-
E Londin, P Loher, AG Telonis, K Quann, P Clark, and Y Jing Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs Proc Natl Acad Sci U S A 112 2015 E1106 E1115
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. E1106-E1115
-
-
Londin, E.1
Loher, P.2
Telonis, A.G.3
Quann, K.4
Clark, P.5
Jing, Y.6
-
12
-
-
84864448111
-
High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
-
G Mullokandov, A Baccarini, A Ruzo, AD Jayaprakash, N Tung, and B Israelow High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries Nat Methods 9 2012 840 846
-
(2012)
Nat Methods
, vol.9
, pp. 840-846
-
-
Mullokandov, G.1
Baccarini, A.2
Ruzo, A.3
Jayaprakash, A.D.4
Tung, N.5
Israelow, B.6
-
13
-
-
80055108220
-
MicroRNA profiling of diverse endothelial cell types
-
MN McCall, OA Kent, J Yu, K Fox-Talbot, AL Zaiman, and MK Halushka MicroRNA profiling of diverse endothelial cell types BMC Med Genomics 4 2011 78
-
(2011)
BMC Med Genomics
, vol.4
, pp. 78
-
-
McCall, M.N.1
Kent, O.A.2
Yu, J.3
Fox-Talbot, K.4
Zaiman, A.L.5
Halushka, M.K.6
-
14
-
-
84903975854
-
Lessons from miR-143/145: The importance of cell-type localization of miRNAs
-
OA Kent, MN McCall, TC Cornish, and MK Halushka Lessons from miR-143/145: the importance of cell-type localization of miRNAs Nucleic Acids Res 42 2014 7528 7538
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 7528-7538
-
-
Kent, O.A.1
McCall, M.N.2
Cornish, T.C.3
Halushka, M.K.4
-
15
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
P Landgraf, M Rusu, R Sheridan, A Sewer, N Iovino, and A Aravin A mammalian microRNA expression atlas based on small RNA library sequencing Cell 129 2007 1401 1414
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
Sewer, A.4
Iovino, N.5
Aravin, A.6
-
17
-
-
85013222187
-
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
-
KW Witwer, EI Buzas, LT Bemis, A Bora, C Lasser, and J Lotvall Standardization of sample collection, isolation and analysis methods in extracellular vesicle research J Extracellular Vesicles 2 2013 10.3402/jev.v2i0.20360
-
(2013)
J Extracellular Vesicles
, vol.2
-
-
Witwer, K.W.1
Buzas, E.I.2
Bemis, L.T.3
Bora, A.4
Lasser, C.5
Lotvall, J.6
-
18
-
-
85016448020
-
Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the International Society for Extracellular Vesicles
-
J Lotvall, AF Hill, F Hochberg, EI Buzas, D Di Vizio, and C Gardiner Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles J Extracellular Vesicles 3 2014 26913
-
(2014)
J Extracellular Vesicles
, vol.3
, pp. 26913
-
-
Lotvall, J.1
Hill, A.F.2
Hochberg, F.3
Buzas, E.I.4
Di Vizio, D.5
Gardiner, C.6
-
19
-
-
84904396495
-
MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells
-
IS Okoye, SM Coomes, VS Pelly, S Czieso, V Papayannopoulos, and T Tolmachova MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells Immunity 41 2014 89 103
-
(2014)
Immunity
, vol.41
, pp. 89-103
-
-
Okoye, I.S.1
Coomes, S.M.2
Pelly, V.S.3
Czieso, S.4
Papayannopoulos, V.5
Tolmachova, T.6
-
20
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
PS Mitchell, RK Parkin, EM Kroh, BR Fritz, SK Wyman, and EL Pogosova-Agadjanyan Circulating microRNAs as stable blood-based markers for cancer detection Proc Natl Acad Sci U S A 105 2008 10513 10518
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
Fritz, B.R.4
Wyman, S.K.5
Pogosova-Agadjanyan, E.L.6
-
21
-
-
84859464569
-
Blood cell origin of circulating microRNAs: A cautionary note for cancer biomarker studies
-
CC Pritchard, E Kroh, B Wood, JD Arroyo, KJ Dougherty, and MM Miyaji Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies Cancer Prev Res (Phila) 5 2012 492 497
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 492-497
-
-
Pritchard, C.C.1
Kroh, E.2
Wood, B.3
Arroyo, J.D.4
Dougherty, K.J.5
Miyaji, M.M.6
-
22
-
-
84859892863
-
MicroRNA profiling: Approaches and considerations
-
CC Pritchard, HH Cheng, and M Tewari MicroRNA profiling: approaches and considerations Nat Rev Genet 13 2012 358 369
-
(2012)
Nat Rev Genet
, vol.13
, pp. 358-369
-
-
Pritchard, C.C.1
Cheng, H.H.2
Tewari, M.3
-
23
-
-
84878757129
-
Plasma processing conditions substantially influence circulating microRNA biomarker levels
-
HH Cheng, HS Yi, Y Kim, EM Kroh, JW Chien, and KD Eaton Plasma processing conditions substantially influence circulating microRNA biomarker levels PLoS One 8 2013 e64795
-
(2013)
PLoS One
, vol.8
, pp. e64795
-
-
Cheng, H.H.1
Yi, H.S.2
Kim, Y.3
Kroh, E.M.4
Chien, J.W.5
Eaton, K.D.6
-
24
-
-
84896277946
-
A critical evaluation of microRNA biomarkers in non-neoplastic disease
-
BA Haider, AS Baras, MN McCall, JA Hertel, TC Cornish, and MK Halushka A critical evaluation of microRNA biomarkers in non-neoplastic disease PLoS One 9 2014 e89565
-
(2014)
PLoS One
, vol.9
, pp. e89565
-
-
Haider, B.A.1
Baras, A.S.2
McCall, M.N.3
Hertel, J.A.4
Cornish, T.C.5
Halushka, M.K.6
-
25
-
-
84924260735
-
Utility of circulating microRNAs as clinical biomarkers for cardiovascular diseases
-
AA Kondkar, and KK Abu-Amero Utility of circulating microRNAs as clinical biomarkers for cardiovascular diseases BioMed Res Int 2015 2015 821823
-
(2015)
BioMed Res Int
, vol.2015
, pp. 821823
-
-
Kondkar, A.A.1
Abu-Amero, K.K.2
-
26
-
-
78549270354
-
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction
-
Y D'Alessandra, P Devanna, F Limana, S Straino, A Di Carlo, and PG Brambilla Circulating microRNAs are new and sensitive biomarkers of myocardial infarction Eur Heart J 31 2010 2765 2773
-
(2010)
Eur Heart J
, vol.31
, pp. 2765-2773
-
-
D'Alessandra, Y.1
Devanna, P.2
Limana, F.3
Straino, S.4
Di Carlo, A.5
Brambilla, P.G.6
-
27
-
-
77954161288
-
Circulating microRNA: A novel potential biomarker for early diagnosis of acute myocardial infarction in humans
-
GK Wang, JQ Zhu, JT Zhang, Q Li, Y Li, and J He Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans Eur Heart J 31 2010 659 666
-
(2010)
Eur Heart J
, vol.31
, pp. 659-666
-
-
Wang, G.K.1
Zhu, J.Q.2
Zhang, J.T.3
Li, Q.4
Li, Y.5
He, J.6
-
28
-
-
79952783637
-
Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease
-
MF Corsten, R Dennert, S Jochems, T Kuznetsova, Y Devaux, and L Hofstra Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease Circ Cardiovasc Genet 3 2010 499 506
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 499-506
-
-
Corsten, M.F.1
Dennert, R.2
Jochems, S.3
Kuznetsova, T.4
Devaux, Y.5
Hofstra, L.6
-
29
-
-
84856112345
-
Relationship between the temporal profile of plasma microRNA and left ventricular remodeling in patients after myocardial infarction
-
MR Zile, SM Mehurg, JE Arroyo, RE Stroud, SM DeSantis, and FG Spinale Relationship between the temporal profile of plasma microRNA and left ventricular remodeling in patients after myocardial infarction Circ Cardiovasc Genet 4 2011 614 619
-
(2011)
Circ Cardiovasc Genet
, vol.4
, pp. 614-619
-
-
Zile, M.R.1
Mehurg, S.M.2
Arroyo, J.E.3
Stroud, R.E.4
Desantis, S.M.5
Spinale, F.G.6
-
30
-
-
79955622637
-
MiRNAs as serum biomarkers for Duchenne muscular dystrophy
-
D Cacchiarelli, I Legnini, J Martone, V Cazzella, A D'Amico, and E Bertini miRNAs as serum biomarkers for Duchenne muscular dystrophy EMBO Mol Med 3 2011 258 265
-
(2011)
EMBO Mol Med
, vol.3
, pp. 258-265
-
-
Cacchiarelli, D.1
Legnini, I.2
Martone, J.3
Cazzella, V.4
D'Amico, A.5
Bertini, E.6
-
31
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
H Valadi, K Ekstrom, A Bossios, M Sjostrand, JJ Lee, and JO Lotvall Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Nat Cell Biol 9 2007 654 659
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
32
-
-
77950889558
-
Functional delivery of viral miRNAs via exosomes
-
DM Pegtel, K Cosmopoulos, DA Thorley-Lawson, MA van Eijndhoven, ES Hopmans, and JL Lindenberg Functional delivery of viral miRNAs via exosomes Proc Natl Acad Sci U S A 107 2010 6328 6333
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 6328-6333
-
-
Pegtel, D.M.1
Cosmopoulos, K.2
Thorley-Lawson, D.A.3
Van Eijndhoven, M.A.4
Hopmans, E.S.5
Lindenberg, J.L.6
-
33
-
-
84922527336
-
Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells
-
ML Squadrito, C Baer, F Burdet, C Maderna, GD Gilfillan, and R Lyle Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells Cell Rep 8 2014 1432 1446
-
(2014)
Cell Rep
, vol.8
, pp. 1432-1446
-
-
Squadrito, M.L.1
Baer, C.2
Burdet, F.3
Maderna, C.4
Gilfillan, G.D.5
Lyle, R.6
-
34
-
-
84862908547
-
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
-
A Montecalvo, AT Larregina, WJ Shufesky, DB Stolz, ML Sullivan, and JM Karlsson Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes Blood 119 2012 756 766
-
(2012)
Blood
, vol.119
, pp. 756-766
-
-
Montecalvo, A.1
Larregina, A.T.2
Shufesky, W.J.3
Stolz, D.B.4
Sullivan, M.L.5
Karlsson, J.M.6
-
35
-
-
84884490899
-
Activated platelets can deliver mRNA regulatory Ago2∗microRNA complexes to endothelial cells via microparticles
-
B Laffont, A Corduan, H Ple, AC Duchez, N Cloutier, and E Boilard Activated platelets can deliver mRNA regulatory Ago2∗microRNA complexes to endothelial cells via microparticles Blood 122 2013 253 261
-
(2013)
Blood
, vol.122
, pp. 253-261
-
-
Laffont, B.1
Corduan, A.2
Ple, H.3
Duchez, A.C.4
Cloutier, N.5
Boilard, E.6
-
36
-
-
84890907806
-
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
-
C Villarroya-Beltri, C Gutierrez-Vazquez, F Sanchez-Cabo, D Perez-Hernandez, J Vazquez, and N Martin-Cofreces Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs Nat Commun 4 2013 2980
-
(2013)
Nat Commun
, vol.4
, pp. 2980
-
-
Villarroya-Beltri, C.1
Gutierrez-Vazquez, C.2
Sanchez-Cabo, F.3
Perez-Hernandez, D.4
Vazquez, J.5
Martin-Cofreces, N.6
-
37
-
-
84899998574
-
MiR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export
-
MB Hudson, ME Woodworth-Hobbs, B Zheng, JA Rahnert, MA Blount, and JL Gooch miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export Am J Physiol Cell Physiol 306 2014 C551 C558
-
(2014)
Am J Physiol Cell Physiol
, vol.306
, pp. C551-C558
-
-
Hudson, M.B.1
Woodworth-Hobbs, M.E.2
Zheng, B.3
Rahnert, J.A.4
Blount, M.A.5
Gooch, J.L.6
-
38
-
-
79953301730
-
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
-
KC Vickers, BT Palmisano, BM Shoucri, RD Shamburek, and AT Remaley MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins Nat Cell Biol 13 2011 423 433
-
(2011)
Nat Cell Biol
, vol.13
, pp. 423-433
-
-
Vickers, K.C.1
Palmisano, B.T.2
Shoucri, B.M.3
Shamburek, R.D.4
Remaley, A.T.5
-
39
-
-
84907906605
-
Quantitative and stoichiometric analysis of the microRNA content of exosomes
-
JR Chevillet, Q Kang, IK Ruf, HA Briggs, LN Vojtech, and SM Hughes Quantitative and stoichiometric analysis of the microRNA content of exosomes Proc Natl Acad Sci U S A 111 2014 14888 14893
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 14888-14893
-
-
Chevillet, J.R.1
Kang, Q.2
Ruf, I.K.3
Briggs, H.A.4
Vojtech, L.N.5
Hughes, S.M.6
-
40
-
-
84860470959
-
Invisible vesicles swarm within the iceberg
-
P Harrison, and C Gardiner Invisible vesicles swarm within the iceberg J Thromb Haemost 10 2012 916 918
-
(2012)
J Thromb Haemost
, vol.10
, pp. 916-918
-
-
Harrison, P.1
Gardiner, C.2
-
41
-
-
84883426378
-
Cardiomyocyte protection by GATA-4 gene engineered mesenchymal stem cells is partially mediated by translocation of miR-221 in microvesicles
-
B Yu, M Gong, Y Wang, RW Millard, Z Pasha, and Y Yang Cardiomyocyte protection by GATA-4 gene engineered mesenchymal stem cells is partially mediated by translocation of miR-221 in microvesicles PLoS One 8 2013 e73304
-
(2013)
PLoS One
, vol.8
, pp. e73304
-
-
Yu, B.1
Gong, M.2
Wang, Y.3
Millard, R.W.4
Pasha, Z.5
Yang, Y.6
-
42
-
-
77449127999
-
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
-
A Zernecke, K Bidzhekov, H Noels, E Shagdarsuren, L Gan, and B Denecke Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection Sci Signal 2 2009 ra81
-
(2009)
Sci Signal
, vol.2
, pp. ra81
-
-
Zernecke, A.1
Bidzhekov, K.2
Noels, H.3
Shagdarsuren, E.4
Gan, L.5
Denecke, B.6
-
43
-
-
34447525068
-
HSP60 trafficking in adult cardiac myocytes: Role of the exosomal pathway
-
S Gupta, and AA Knowlton HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway Am J Physiol Heart Circ Physiol 292 2007 H3052 H3056
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H3052-H3056
-
-
Gupta, S.1
Knowlton, A.A.2
-
44
-
-
84898476721
-
Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
-
W Zhou, MY Fong, Y Min, G Somlo, L Liu, and MR Palomares Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis Cancer Cell 25 2014 501 515
-
(2014)
Cancer Cell
, vol.25
, pp. 501-515
-
-
Zhou, W.1
Fong, M.Y.2
Min, Y.3
Somlo, G.4
Liu, L.5
Palomares, M.R.6
-
45
-
-
84876248584
-
Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis
-
N Kosaka, H Iguchi, K Hagiwara, Y Yoshioka, F Takeshita, and T Ochiya Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis J Biol Chem 288 2013 10849 10859
-
(2013)
J Biol Chem
, vol.288
, pp. 10849-10859
-
-
Kosaka, N.1
Iguchi, H.2
Hagiwara, K.3
Yoshioka, Y.4
Takeshita, F.5
Ochiya, T.6
-
46
-
-
79955070767
-
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
-
M Mittelbrunn, C Gutierrez-Vazquez, C Villarroya-Beltri, S Gonzalez, F Sanchez-Cabo, and MA Gonzalez Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells Nat Commun 2 2011 282
-
(2011)
Nat Commun
, vol.2
, pp. 282
-
-
Mittelbrunn, M.1
Gutierrez-Vazquez, C.2
Villarroya-Beltri, C.3
Gonzalez, S.4
Sanchez-Cabo, F.5
Gonzalez, M.A.6
-
47
-
-
84868475728
-
MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
-
E van Rooij, and EN Olson MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles Nat Rev Drug Discov 11 2012 860 872
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 860-872
-
-
Van Rooij, E.1
Olson, E.N.2
-
48
-
-
84899128394
-
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
-
C Bang, S Batkai, S Dangwal, SK Gupta, A Foinquinos, and A Holzmann Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy J Clin Invest 124 2014 2136 2146
-
(2014)
J Clin Invest
, vol.124
, pp. 2136-2146
-
-
Bang, C.1
Batkai, S.2
Dangwal, S.3
Gupta, S.K.4
Foinquinos, A.5
Holzmann, A.6
-
49
-
-
84897808834
-
Ischemic preconditioning potentiates the protective effect of stem cells through secretion of exosomes by targeting Mecp2 via miR-22
-
Y Feng, W Huang, M Wani, X Yu, and M Ashraf Ischemic preconditioning potentiates the protective effect of stem cells through secretion of exosomes by targeting Mecp2 via miR-22 PLoS One 9 2014 e88685
-
(2014)
PLoS One
, vol.9
, pp. e88685
-
-
Feng, Y.1
Huang, W.2
Wani, M.3
Yu, X.4
Ashraf, M.5
-
50
-
-
84860157611
-
Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1
-
X Wang, H Zhu, X Zhang, Y Liu, J Chen, and M Medvedovic Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1 Cardiovasc Res 94 2012 379 390
-
(2012)
Cardiovasc Res
, vol.94
, pp. 379-390
-
-
Wang, X.1
Zhu, H.2
Zhang, X.3
Liu, Y.4
Chen, J.5
Medvedovic, M.6
-
51
-
-
84877116748
-
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
-
J Halkein, SP Tabruyn, M Ricke-Hoch, A Haghikia, NQ Nguyen, and M Scherr MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy J Clin Invest 123 2013 2143 2154
-
(2013)
J Clin Invest
, vol.123
, pp. 2143-2154
-
-
Halkein, J.1
Tabruyn, S.P.2
Ricke-Hoch, M.3
Haghikia, A.4
Nguyen, N.Q.5
Scherr, M.6
-
52
-
-
84899980641
-
Exosomes as critical agents of cardiac regeneration triggered by cell therapy
-
AG Ibrahim, K Cheng, and E Marban Exosomes as critical agents of cardiac regeneration triggered by cell therapy Stem Cell Rep 2 2014 606 619
-
(2014)
Stem Cell Rep
, vol.2
, pp. 606-619
-
-
Ibrahim, A.G.1
Cheng, K.2
Marban, E.3
-
53
-
-
84907337461
-
Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction
-
L Barile, V Lionetti, E Cervio, M Matteucci, M Gherghiceanu, and LM Popescu Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction Cardiovasc Res 103 2014 530 541
-
(2014)
Cardiovasc Res
, vol.103
, pp. 530-541
-
-
Barile, L.1
Lionetti, V.2
Cervio, E.3
Matteucci, M.4
Gherghiceanu, M.5
Popescu, L.M.6
-
54
-
-
84872063933
-
AngiomiR-126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: Role for proangiogenic effects and alterations in type 2 diabetics
-
P Mocharla, S Briand, G Giannotti, C Dorries, P Jakob, and F Paneni AngiomiR-126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: role for proangiogenic effects and alterations in type 2 diabetics Blood 121 2013 226 236
-
(2013)
Blood
, vol.121
, pp. 226-236
-
-
Mocharla, P.1
Briand, S.2
Giannotti, G.3
Dorries, C.4
Jakob, P.5
Paneni, F.6
-
55
-
-
77954257796
-
Secreted monocytic miR-150 enhances targeted endothelial cell migration
-
Y Zhang, D Liu, X Chen, J Li, L Li, and Z Bian Secreted monocytic miR-150 enhances targeted endothelial cell migration Mol Cell 39 2010 133 144
-
(2010)
Mol Cell
, vol.39
, pp. 133-144
-
-
Zhang, Y.1
Liu, D.2
Chen, X.3
Li, J.4
Li, L.5
Bian, Z.6
-
56
-
-
84880475762
-
Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells
-
BW van Balkom, OG de Jong, M Smits, J Brummelman, K den Ouden, and PM de Bree Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells Blood 121 2013 3997 4006
-
(2013)
Blood
, vol.121
, pp. 3997-4006
-
-
Van Balkom, B.W.1
De Jong, O.G.2
Smits, M.3
Brummelman, J.4
Den Ouden, K.5
De Bree, P.M.6
-
57
-
-
84904768520
-
Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells
-
X Wang, W Huang, G Liu, W Cai, RW Millard, and Y Wang Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells J Mol Cell Cardiol 74 2014 139 150
-
(2014)
J Mol Cell Cardiol
, vol.74
, pp. 139-150
-
-
Wang, X.1
Huang, W.2
Liu, G.3
Cai, W.4
Millard, R.W.5
Wang, Y.6
-
58
-
-
84922105441
-
Identification of therapeutic covariant microRNA clusters in hypoxia-treated cardiac progenitor cell exosomes using systems biology
-
WD Gray, KM French, S Ghosh-Choudhary, JT Maxwell, ME Brown, and MO Platt Identification of therapeutic covariant microRNA clusters in hypoxia-treated cardiac progenitor cell exosomes using systems biology Circ Res 116 2015 255 263
-
(2015)
Circ Res
, vol.116
, pp. 255-263
-
-
Gray, W.D.1
French, K.M.2
Ghosh-Choudhary, S.3
Maxwell, J.T.4
Brown, M.E.5
Platt, M.O.6
-
59
-
-
84908110212
-
Cross talk of combined gene and cell therapy in ischemic heart disease: Role of exosomal microRNA transfer
-
SG Ong, WH Lee, M Huang, D Dey, K Kodo, and V Sanchez-Freire Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer Circulation 130 2014 S60 S69
-
(2014)
Circulation
, vol.130
, pp. S60-S69
-
-
Ong, S.G.1
Lee, W.H.2
Huang, M.3
Dey, D.4
Kodo, K.5
Sanchez-Freire, V.6
-
60
-
-
84857708170
-
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
-
E Hergenreider, S Heydt, K Treguer, T Boettger, AJ Horrevoets, and AM Zeiher Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs Nat Cell Biol 14 2012 249 256
-
(2012)
Nat Cell Biol
, vol.14
, pp. 249-256
-
-
Hergenreider, E.1
Heydt, S.2
Treguer, K.3
Boettger, T.4
Horrevoets, A.J.5
Zeiher, A.M.6
-
61
-
-
84859753308
-
Does the voltage dependent anion channel modulate cardiac ischemia-reperfusion injury?
-
S Das, C Steenbergen, and E Murphy Does the voltage dependent anion channel modulate cardiac ischemia-reperfusion injury? Biochim Biophys Acta 2012 1818 1451 1456
-
(1818)
Biochim Biophys Acta
, vol.2012
, pp. 1451-1456
-
-
Das, S.1
Steenbergen, C.2
Murphy, E.3
-
62
-
-
0022970945
-
Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
-
CE Murry, RB Jennings, and KA Reimer Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium Circulation 74 1986 1124 1136
-
(1986)
Circulation
, vol.74
, pp. 1124-1136
-
-
Murry, C.E.1
Jennings, R.B.2
Reimer, K.A.3
-
63
-
-
57049157046
-
Endogenous microRNAs induced by heat-shock reduce myocardial infarction following ischemia-reperfusion in mice
-
C Yin, X Wang, and RC Kukreja Endogenous microRNAs induced by heat-shock reduce myocardial infarction following ischemia-reperfusion in mice FEBS Lett 582 2008 4137 4142
-
(2008)
FEBS Lett
, vol.582
, pp. 4137-4142
-
-
Yin, C.1
Wang, X.2
Kukreja, R.C.3
-
64
-
-
84855350458
-
Inhibition of miR-15 protects against cardiac ischemic injury
-
TG Hullinger, RL Montgomery, AG Seto, BA Dickinson, HM Semus, and JM Lynch Inhibition of miR-15 protects against cardiac ischemic injury Circ Res 110 2012 71 81
-
(2012)
Circ Res
, vol.110
, pp. 71-81
-
-
Hullinger, T.G.1
Montgomery, R.L.2
Seto, A.G.3
Dickinson, B.A.4
Semus, H.M.5
Lynch, J.M.6
-
65
-
-
0027401466
-
Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion
-
K Przyklenk, B Bauer, M Ovize, RA Kloner, and P Whittaker Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion Circulation 87 1993 893 899
-
(1993)
Circulation
, vol.87
, pp. 893-899
-
-
Przyklenk, K.1
Bauer, B.2
Ovize, M.3
Kloner, R.A.4
Whittaker, P.5
-
66
-
-
84894239930
-
Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles
-
Z Giricz, ZV Varga, T Baranyai, P Sipos, K Paloczi, and A Kittel Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles J Mol Cell Cardiol 68 2014 75 78
-
(2014)
J Mol Cell Cardiol
, vol.68
, pp. 75-78
-
-
Giricz, Z.1
Varga, Z.V.2
Baranyai, T.3
Sipos, P.4
Paloczi, K.5
Kittel, A.6
-
67
-
-
83655193397
-
Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: Implication for therapy in Rett syndrome
-
MD McCauley, T Wang, E Mike, J Herrera, DL Beavers, and TW Huang Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome Sci Transl Med 3 2011 113ra25
-
(2011)
Sci Transl Med
, vol.3
, pp. 113ra25
-
-
McCauley, M.D.1
Wang, T.2
Mike, E.3
Herrera, J.4
Beavers, D.L.5
Huang, T.W.6
-
68
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
RE Amir, IB Van den Veyver, M Wan, CQ Tran, U Francke, and HY Zoghbi Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 Nat Genet 23 1999 185 188
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
69
-
-
84904525967
-
MicroRNA-144 is a circulating effector of remote ischemic preconditioning
-
J Li, S Rohailla, N Gelber, J Rutka, N Sabah, and RA Gladstone MicroRNA-144 is a circulating effector of remote ischemic preconditioning Basic Res Cardiol 109 2014 423
-
(2014)
Basic Res Cardiol
, vol.109
, pp. 423
-
-
Li, J.1
Rohailla, S.2
Gelber, N.3
Rutka, J.4
Sabah, N.5
Gladstone, R.A.6
-
70
-
-
84867186068
-
Microparticle release in remote ischemic conditioning mechanism
-
J Jeanneteau, P Hibert, MC Martinez, S Tual-Chalot, S Tamareille, and A Furber Microparticle release in remote ischemic conditioning mechanism Am J Physiol Heart Circ Physiol 303 2012 H871 H877
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
, pp. H871-H877
-
-
Jeanneteau, J.1
Hibert, P.2
Martinez, M.C.3
Tual-Chalot, S.4
Tamareille, S.5
Furber, A.6
-
71
-
-
84902975038
-
Heart failure with preserved ejection fraction: Mechanisms, clinical features, and therapies
-
K Sharma, and DA Kass Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies Circ Res 115 2014 79 96
-
(2014)
Circ Res
, vol.115
, pp. 79-96
-
-
Sharma, K.1
Kass, D.A.2
-
72
-
-
33947239659
-
The failing heart - An engine out of fuel
-
S Neubauer The failing heart - an engine out of fuel N Engl J Med 356 2007 1140 1151
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
73
-
-
33845317603
-
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
-
E van Rooij, LB Sutherland, N Liu, AH Williams, J McAnally, and RD Gerard A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure Proc Natl Acad Sci U S A 103 2006 18255 18260
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18255-18260
-
-
Van Rooij, E.1
Sutherland, L.B.2
Liu, N.3
Williams, A.H.4
McAnally, J.5
Gerard, R.D.6
-
74
-
-
84859608013
-
Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells
-
A Waldenstrom, N Genneback, U Hellman, and G Ronquist Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells PLoS One 7 2012 e34653
-
(2012)
PLoS One
, vol.7
, pp. e34653
-
-
Waldenstrom, A.1
Genneback, N.2
Hellman, U.3
Ronquist, G.4
-
75
-
-
33846815521
-
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy
-
D Hilfiker-Kleiner, K Kaminski, E Podewski, T Bonda, A Schaefer, and K Sliwa A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy Cell 128 2007 589 600
-
(2007)
Cell
, vol.128
, pp. 589-600
-
-
Hilfiker-Kleiner, D.1
Kaminski, K.2
Podewski, E.3
Bonda, T.4
Schaefer, A.5
Sliwa, K.6
-
77
-
-
84901318452
-
An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration
-
RR Chivukula, G Shi, A Acharya, EW Mills, LR Zeitels, and JL Anandam An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration Cell 157 2014 1104 1116
-
(2014)
Cell
, vol.157
, pp. 1104-1116
-
-
Chivukula, R.R.1
Shi, G.2
Acharya, A.3
Mills, E.W.4
Zeitels, L.R.5
Anandam, J.L.6
-
78
-
-
84930929504
-
TGFbeta triggers miR-143/145 transfer from smooth muscle cells to endothelial cells, thereby modulating vessel stabilization
-
[Epub 2015 Mar 23]
-
M Climent-Salarich, M Quintavalle, M Miragoli, J Chen, G Condorelli, and L Elia TGFbeta triggers miR-143/145 transfer from smooth muscle cells to endothelial cells, thereby modulating vessel stabilization Circ Res 2015 [Epub 2015 Mar 23]
-
(2015)
Circ Res
-
-
Climent-Salarich, M.1
Quintavalle, M.2
Miragoli, M.3
Chen, J.4
Condorelli, G.5
Elia, L.6
-
79
-
-
14844295052
-
Platelet microparticles and soluble P selectin in peripheral artery disease: Relationship to extent of disease and platelet activation markers
-
KT Tan, MH Tayebjee, C Lynd, AD Blann, and GY Lip Platelet microparticles and soluble P selectin in peripheral artery disease: relationship to extent of disease and platelet activation markers Ann Med 37 2005 61 66
-
(2005)
Ann Med
, vol.37
, pp. 61-66
-
-
Tan, K.T.1
Tayebjee, M.H.2
Lynd, C.3
Blann, A.D.4
Lip, G.Y.5
-
80
-
-
0033580603
-
Platelet microparticles promote platelet interaction with subendothelial matrix in a glycoprotein IIb/IIIa-dependent mechanism
-
M Merten, R Pakala, P Thiagarajan, and CR Benedict Platelet microparticles promote platelet interaction with subendothelial matrix in a glycoprotein IIb/IIIa-dependent mechanism Circulation 99 1999 2577 2582
-
(1999)
Circulation
, vol.99
, pp. 2577-2582
-
-
Merten, M.1
Pakala, R.2
Thiagarajan, P.3
Benedict, C.R.4
-
81
-
-
0032128299
-
Modulation of monocyte-endothelial cell interactions by platelet microparticles
-
OP Barry, D Pratico, RC Savani, and GA FitzGerald Modulation of monocyte-endothelial cell interactions by platelet microparticles J Clin Invest 102 1998 136 144
-
(1998)
J Clin Invest
, vol.102
, pp. 136-144
-
-
Barry, O.P.1
Pratico, D.2
Savani, R.C.3
Fitzgerald, G.A.4
-
82
-
-
84874230935
-
Circulating microRNAs as novel biomarkers for platelet activation
-
P Willeit, A Zampetaki, K Dudek, D Kaudewitz, A King, and NS Kirkby Circulating microRNAs as novel biomarkers for platelet activation Circ Res 112 2013 595 600
-
(2013)
Circ Res
, vol.112
, pp. 595-600
-
-
Willeit, P.1
Zampetaki, A.2
Dudek, K.3
Kaudewitz, D.4
King, A.5
Kirkby, N.S.6
-
83
-
-
43049159221
-
Circulating endothelial microparticles correlate inversely with endothelial function in patients with ischemic left ventricular dysfunction
-
D Bulut, K Maier, N Bulut-Streich, J Borgel, C Hanefeld, and A Mugge Circulating endothelial microparticles correlate inversely with endothelial function in patients with ischemic left ventricular dysfunction J Card Fail 14 2008 336 340
-
(2008)
J Card Fail
, vol.14
, pp. 336-340
-
-
Bulut, D.1
Maier, K.2
Bulut-Streich, N.3
Borgel, J.4
Hanefeld, C.5
Mugge, A.6
-
84
-
-
33644831131
-
Circulating CD31 +/annexin v + apoptotic microparticles correlate with coronary endothelial function in patients with coronary artery disease
-
N Werner, S Wassmann, P Ahlers, S Kosiol, and G Nickenig Circulating CD31 +/annexin V + apoptotic microparticles correlate with coronary endothelial function in patients with coronary artery disease Arterioscler Thromb Vasc Biol 26 2006 112 116
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 112-116
-
-
Werner, N.1
Wassmann, S.2
Ahlers, P.3
Kosiol, S.4
Nickenig, G.5
-
85
-
-
77957259803
-
Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
-
A Zampetaki, S Kiechl, I Drozdov, P Willeit, U Mayr, and M Prokopi Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes Circ Res 107 2010 810 817
-
(2010)
Circ Res
, vol.107
, pp. 810-817
-
-
Zampetaki, A.1
Kiechl, S.2
Drozdov, I.3
Willeit, P.4
Mayr, U.5
Prokopi, M.6
-
86
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
HL Janssen, HW Reesink, EJ Lawitz, S Zeuzem, M Rodriguez-Torres, and K Patel Treatment of HCV infection by targeting microRNA N Engl J Med 368 2013 1685 1694
-
(2013)
N Engl J Med
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
-
87
-
-
84893628843
-
Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates
-
K Kelnar, HJ Peltier, N Leatherbury, J Stoudemire, and AG Bader Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates Anal Chem 86 2014 1534 1542
-
(2014)
Anal Chem
, vol.86
, pp. 1534-1542
-
-
Kelnar, K.1
Peltier, H.J.2
Leatherbury, N.3
Stoudemire, J.4
Bader, A.G.5
-
88
-
-
84862279805
-
Nuclear miRNA regulates the mitochondrial genome in the heart
-
S Das, M Ferlito, OA Kent, K Fox Talbot, R Wang, and D Liu Nuclear miRNA regulates the mitochondrial genome in the heart Circ Res 110 2012 1596 1603
-
(2012)
Circ Res
, vol.110
, pp. 1596-1603
-
-
Das, S.1
Ferlito, M.2
Kent, O.A.3
Fox Talbot, K.4
Wang, R.5
Liu, D.6
|