TGFβ triggers miR-143/145 transfer from smooth muscle cells to endothelial cells, thereby modulating vessel stabilization

Circulation Research

Volumn 116, Issue 11, 2015, Pages 1753-1764

  Climent, Montserrat ^a   Quintavalle, Manuela ^b   Miragoli, Michele ^b,e   Chen, Ju ^f   Condorelli, Gianluigi ^b,c,d   Elia, Leonardo ^b,c  

^a IRCCS MULTIMEDICA   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c Milan Unit   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e UNIVERSITY OF PARMA   (Italy)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Angiogenesis effect; Endothelial cells; microRNAs; Smooth muscle myocytes

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; BETA INTEGRIN; HEXOKINASE; HEXOKINASE II; MATRIGEL; MICRORNA 143; MICRORNA 145; NANOTUBE; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; INTEGRIN BETA8; MICRORNA; MIRN143 MICRORNA, MOUSE; MIRN145 MICRORNA, MOUSE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ESSENTIAL GENE; EX VIVO STUDY; GENE OVEREXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD VESSEL; C57BL MOUSE; CELL COMMUNICATION; CELL CULTURE; CELL SURFACE; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TRANSPORT AT THE CELLULAR LEVEL; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; BENZAMIDES; BIOLOGICAL TRANSPORT; BLOOD VESSELS; BLOTTING, WESTERN; CELL COMMUNICATION; CELL SURFACE EXTENSIONS; CELLS, CULTURED; COCULTURE TECHNIQUES; DIOXOLES; GENE EXPRESSION REGULATION; HEXOKINASE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTEGRIN BETA CHAINS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MYOCYTES, SMOOTH MUSCLE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84930929504     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.305178     Document Type: Article

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