Impaired firing properties of dentate granule neurons in an Alzheimer’s disease animal model are rescued by PPARγ agonism

Journal of Neurophysiology

Volumn 113, Issue 6, 2015, Pages 1712-1726

  Nenov, Miroslav N ^a   Tempia, Filippo ^a   Denner, Larry ^a   Dineley, Kelly T ^a   Laezza, Fernanda ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Alzheimer s disease; Dentate gyrus; Excitability; Patch clamp; Peroxisome proliferator activated receptor

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL MEMBRANE DEPOLARIZATION; CELL POPULATION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE NUCLEUS; DRUG ACTIVITY; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; FEMALE; GRANULE CELL; MALE; MOUSE; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; REFRACTORY PERIOD; SPIKE WAVE; TG2576 MOUSE; ACTION POTENTIAL; AGONISTS; ANIMAL; C57BL MOUSE; COGNITION; CYTOLOGY; DRUG EFFECTS; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACTION POTENTIALS; ALZHEIMER DISEASE; ANIMALS; COGNITION; ENTORHINAL CORTEX; MALE; MICE; MICE, INBRED C57BL; NEURONS; PPAR GAMMA; THIAZOLIDINEDIONES;

EID: 84930840553     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00419.2014     Document Type: Article

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