메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 84877844222     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064318     Document Type: Article
Times cited : (73)

References (73)
  • 1
    • 0025770134 scopus 로고
    • The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease
    • Price JL, Davis PB, Morris JC, White DL, (1991) The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging 12: 295-312.
    • (1991) Neurobiol Aging , vol.12 , pp. 295-312
    • Price, J.L.1    Davis, P.B.2    Morris, J.C.3    White, D.L.4
  • 3
    • 0021256895 scopus 로고
    • Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner GG, Wong CW, (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120: 885-890.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 4
    • 0022724941 scopus 로고
    • Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
    • Ihara Y, Nukina N, Miura R, Ogawara M, (1986) Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J Biochem 99: 1807-1810.
    • (1986) J Biochem , vol.99 , pp. 1807-1810
    • Ihara, Y.1    Nukina, N.2    Miura, R.3    Ogawara, M.4
  • 5
    • 0022744803 scopus 로고
    • Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
    • Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, et al. (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A 83: 4913-4917.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 4913-4917
    • Grundke-Iqbal, I.1    Iqbal, K.2    Tung, Y.C.3    Quinlan, M.4    Wisniewski, H.M.5
  • 6
    • 0009364134 scopus 로고
    • Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease
    • Kosik KS, Joachim CL, Selkoe DJ, (1986) Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease. Proc Natl Acad Sci U S A 83: 4044-4048.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 4044-4048
    • Kosik, K.S.1    Joachim, C.L.2    Selkoe, D.J.3
  • 7
  • 8
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-beta protein assembly in the brain impairs memory
    • Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, et al. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-357.
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesne, S.1    Koh, M.T.2    Kotilinek, L.3    Kayed, R.4    Glabe, C.G.5
  • 9
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
    • Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, et al. (2002) Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416: 535-539.
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5
  • 10
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, et al. (2011) Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association 7: 280-292.
    • (2011) Alzheimer's & Dementia: The Journal of the Alzheimer's Association , vol.7 , pp. 280-292
    • Sperling, R.A.1    Aisen, P.S.2    Beckett, L.A.3    Bennett, D.A.4    Craft, S.5
  • 11
    • 33846466652 scopus 로고    scopus 로고
    • Plaques, tangles, and memory loss in mouse models of neurodegeneration
    • Eriksen JL, Janus CG, (2007) Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behav Genet 37: 79-100.
    • (2007) Behav Genet , vol.37 , pp. 79-100
    • Eriksen, J.L.1    Janus, C.G.2
  • 12
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
    • Palop JJ, Mucke L, (2010) Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 13: 812-818.
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 13
    • 78049283756 scopus 로고    scopus 로고
    • Transsynaptic progression of amyloid-beta-induced neuronal dysfunction within the entorhinal-hippocampal network
    • Harris JA, Devidze N, Verret L, Ho K, Halabisky B, et al. (2010) Transsynaptic progression of amyloid-beta-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron 68: 428-441.
    • (2010) Neuron , vol.68 , pp. 428-441
    • Harris, J.A.1    Devidze, N.2    Verret, L.3    Ho, K.4    Halabisky, B.5
  • 15
    • 78651278360 scopus 로고    scopus 로고
    • A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation
    • Noebels J, (2011) A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia 52 Suppl 1: 39-46.
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 1 , pp. 39-46
    • Noebels, J.1
  • 16
    • 63849180498 scopus 로고    scopus 로고
    • Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy
    • Minkeviciene R, Rheims S, Dobszay MB, Zilberter M, Hartikainen J, et al. (2009) Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci 29: 3453-3462.
    • (2009) J Neurosci , vol.29 , pp. 3453-3462
    • Minkeviciene, R.1    Rheims, S.2    Dobszay, M.B.3    Zilberter, M.4    Hartikainen, J.5
  • 17
    • 80052619181 scopus 로고    scopus 로고
    • Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease
    • Brown JT, Chin J, Leiser SC, Pangalos MN, Randall AD, (2011) Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease. Neurobiology of aging 32: 2109 e2101-2114.
    • (2011) Neurobiology of Aging , vol.32
    • Brown, J.T.1    Chin, J.2    Leiser, S.C.3    Pangalos, M.N.4    Randall, A.D.5
  • 18
    • 84934441665 scopus 로고    scopus 로고
    • Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling
    • Palop JJ, Mucke L, Roberson ED, (2011) Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. Methods in molecular biology 670: 245-262.
    • (2011) Methods in Molecular Biology , vol.670 , pp. 245-262
    • Palop, J.J.1    Mucke, L.2    Roberson, E.D.3
  • 20
    • 79952386386 scopus 로고    scopus 로고
    • Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels
    • Ziyatdinova S, Gurevicius K, Kutchiashvili N, Bolkvadze T, Nissinen J, et al. (2011) Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels. Epilepsy research 94: 75-85.
    • (2011) Epilepsy Research , vol.94 , pp. 75-85
    • Ziyatdinova, S.1    Gurevicius, K.2    Kutchiashvili, N.3    Bolkvadze, T.4    Nissinen, J.5
  • 21
    • 84860334015 scopus 로고    scopus 로고
    • Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
    • Verret L, Mann EO, Hang GB, Barth AM, Cobos I, et al. (2012) Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 149: 708-721.
    • (2012) Cell , vol.149 , pp. 708-721
    • Verret, L.1    Mann, E.O.2    Hang, G.B.3    Barth, A.M.4    Cobos, I.5
  • 22
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
    • Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, et al. (2008) Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321: 1686-1689.
    • (2008) Science , vol.321 , pp. 1686-1689
    • Busche, M.A.1    Eichhoff, G.2    Adelsberger, H.3    Abramowski, D.4    Wiederhold, K.H.5
  • 23
    • 77952521799 scopus 로고    scopus 로고
    • Alzheimer's disease and neuronal network activity
    • Gleichmann M, Mattson MP, (2010) Alzheimer's disease and neuronal network activity. Neuromolecular Med 12: 44-47.
    • (2010) Neuromolecular Med , vol.12 , pp. 44-47
    • Gleichmann, M.1    Mattson, M.P.2
  • 24
    • 0348048773 scopus 로고    scopus 로고
    • Neocortical seizures: initiation, development and cessation
    • Timofeev I, Steriade M, (2004) Neocortical seizures: initiation, development and cessation. Neuroscience 123: 299-336.
    • (2004) Neuroscience , vol.123 , pp. 299-336
    • Timofeev, I.1    Steriade, M.2
  • 25
    • 0030054677 scopus 로고    scopus 로고
    • Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus
    • Avoli M, Louvel J, Kurcewicz I, Pumain R, Barbarosie M, (1996) Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus. J Physiol 493(Pt 3): 707-717.
    • (1996) J Physiol , vol.493 , Issue.Pt 3 , pp. 707-717
    • Avoli, M.1    Louvel, J.2    Kurcewicz, I.3    Pumain, R.4    Barbarosie, M.5
  • 26
    • 0021199729 scopus 로고
    • Feed-forward inhibition in the hippocampal formation
    • Buzsaki G, (1984) Feed-forward inhibition in the hippocampal formation. Prog Neurobiol 22: 131-153.
    • (1984) Prog Neurobiol , vol.22 , pp. 131-153
    • Buzsaki, G.1
  • 28
    • 3042523540 scopus 로고    scopus 로고
    • Neuronal oscillations in cortical networks
    • Buzsaki G, Draguhn A, (2004) Neuronal oscillations in cortical networks. Science 304: 1926-1929.
    • (2004) Science , vol.304 , pp. 1926-1929
    • Buzsaki, G.1    Draguhn, A.2
  • 29
    • 8344243726 scopus 로고    scopus 로고
    • VSDI: a new era in functional imaging of cortical dynamics
    • Grinvald A, Hildesheim R, (2004) VSDI: a new era in functional imaging of cortical dynamics. Nat Rev Neurosci 5: 874-885.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 874-885
    • Grinvald, A.1    Hildesheim, R.2
  • 30
    • 33751109475 scopus 로고    scopus 로고
    • Massive and specific dysregulation of direct cortical input to the hippocampus in temporal lobe epilepsy
    • Ang CW, Carlson GC, Coulter DA, (2006) Massive and specific dysregulation of direct cortical input to the hippocampus in temporal lobe epilepsy. J Neurosci 26: 11850-11856.
    • (2006) J Neurosci , vol.26 , pp. 11850-11856
    • Ang, C.W.1    Carlson, G.C.2    Coulter, D.A.3
  • 31
    • 79954474953 scopus 로고    scopus 로고
    • Hippocampal microcircuit dynamics probed using optical imaging approaches
    • Coulter DA, Yue C, Ang CW, Weissinger F, Goldberg E, et al. (2011) Hippocampal microcircuit dynamics probed using optical imaging approaches. J Physiol 589: 1893-1903.
    • (2011) J Physiol , vol.589 , pp. 1893-1903
    • Coulter, D.A.1    Yue, C.2    Ang, C.W.3    Weissinger, F.4    Goldberg, E.5
  • 32
    • 52449096449 scopus 로고    scopus 로고
    • Propagating waves of activity in the neocortex: what they are, what they do
    • Wu JY, Xiaoying H, Chuan Z, (2008) Propagating waves of activity in the neocortex: what they are, what they do. Neuroscientist 14: 487-502.
    • (2008) Neuroscientist , vol.14 , pp. 487-502
    • Wu, J.Y.1    Xiaoying, H.2    Chuan, Z.3
  • 34
    • 34247222730 scopus 로고    scopus 로고
    • Multimodal fast optical interrogation of neural circuitry
    • Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, et al. (2007) Multimodal fast optical interrogation of neural circuitry. Nature 446: 633-639.
    • (2007) Nature , vol.446 , pp. 633-639
    • Zhang, F.1    Wang, L.P.2    Brauner, M.3    Liewald, J.F.4    Kay, K.5
  • 35
    • 84863993867 scopus 로고    scopus 로고
    • beta-Adrenergic modulation of spontaneous spatiotemporal activity patterns and synchrony in hyperexcitable hippocampal circuits
    • Hazra A, Rosenbaum R, Bodmann B, Cao S, Josic K, et al. (2012) beta-Adrenergic modulation of spontaneous spatiotemporal activity patterns and synchrony in hyperexcitable hippocampal circuits. J Neurophysiol 108: 658-671.
    • (2012) J Neurophysiol , vol.108 , pp. 658-671
    • Hazra, A.1    Rosenbaum, R.2    Bodmann, B.3    Cao, S.4    Josic, K.5
  • 36
    • 34548264782 scopus 로고    scopus 로고
    • Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
    • Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, et al. (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55: 697-711.
    • (2007) Neuron , vol.55 , pp. 697-711
    • Palop, J.J.1    Chin, J.2    Roberson, E.D.3    Wang, J.4    Thwin, M.T.5
  • 37
    • 65249091454 scopus 로고    scopus 로고
    • Epilepsy and cognitive impairments in Alzheimer disease
    • Palop JJ, Mucke L, (2009) Epilepsy and cognitive impairments in Alzheimer disease. Arch Neurol 66: 435-440.
    • (2009) Arch Neurol , vol.66 , pp. 435-440
    • Palop, J.J.1    Mucke, L.2
  • 38
    • 78651506630 scopus 로고    scopus 로고
    • Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease
    • Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, et al. (2011) Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. J Neurosci 31: 700-711.
    • (2011) J Neurosci , vol.31 , pp. 700-711
    • Roberson, E.D.1    Halabisky, B.2    Yoo, J.W.3    Yao, J.4    Chin, J.5
  • 39
    • 26244453388 scopus 로고    scopus 로고
    • Exploratory activity and spatial learning in 12-month-old APP(695)SWE/co+PS1/DeltaE9 mice with amyloid plaques
    • Lalonde R, Kim HD, Maxwell JA, Fukuchi K, (2005) Exploratory activity and spatial learning in 12-month-old APP(695)SWE/co+PS1/DeltaE9 mice with amyloid plaques. Neurosci Lett 390: 87-92.
    • (2005) Neurosci Lett , vol.390 , pp. 87-92
    • Lalonde, R.1    Kim, H.D.2    Maxwell, J.A.3    Fukuchi, K.4
  • 40
    • 77952875375 scopus 로고    scopus 로고
    • Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1deltaE9-deleted transgenic mice model of ss-amyloidosis
    • Volianskis A, Kostner R, Molgaard M, Hass S, Jensen MS, (2010) Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1deltaE9-deleted transgenic mice model of ss-amyloidosis. Neurobiol Aging 31: 1173-1187.
    • (2010) Neurobiol Aging , vol.31 , pp. 1173-1187
    • Volianskis, A.1    Kostner, R.2    Molgaard, M.3    Hass, S.4    Jensen, M.S.5
  • 41
    • 0034668168 scopus 로고    scopus 로고
    • Quantification of optical signals with electrophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices
    • Tominaga T, Tominaga Y, Yamada H, Matsumoto G, Ichikawa M, (2000) Quantification of optical signals with electrophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices. J Neurosci Methods 102: 11-23.
    • (2000) J Neurosci Methods , vol.102 , pp. 11-23
    • Tominaga, T.1    Tominaga, Y.2    Yamada, H.3    Matsumoto, G.4    Ichikawa, M.5
  • 42
    • 39449091602 scopus 로고    scopus 로고
    • In vitro functional imaging in brain slices using fast voltage-sensitive dye imaging combined with whole-cell patch recording
    • Carlson GC, Coulter DA, (2008) In vitro functional imaging in brain slices using fast voltage-sensitive dye imaging combined with whole-cell patch recording. Nat Protoc 3: 249-255.
    • (2008) Nat Protoc , vol.3 , pp. 249-255
    • Carlson, G.C.1    Coulter, D.A.2
  • 43
    • 79954562389 scopus 로고    scopus 로고
    • Neurogliaform cells in the molecular layer of the dentate gyrus as feed-forward gamma-aminobutyric acidergic modulators of entorhinal-hippocampal interplay
    • Armstrong C, Szabadics J, Tamas G, Soltesz I, (2011) Neurogliaform cells in the molecular layer of the dentate gyrus as feed-forward gamma-aminobutyric acidergic modulators of entorhinal-hippocampal interplay. J Comp Neurol 519: 1476-1491.
    • (2011) J Comp Neurol , vol.519 , pp. 1476-1491
    • Armstrong, C.1    Szabadics, J.2    Tamas, G.3    Soltesz, I.4
  • 46
    • 84866539183 scopus 로고    scopus 로고
    • Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: From animal models to human findings
    • D′Amelio M, Rossini PM, (2012) Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: From animal models to human findings. Prog Neurobiol.
    • (2012) Prog Neurobiol
    • DAmelio, M.1    Rossini, P.M.2
  • 48
    • 77952484484 scopus 로고    scopus 로고
    • Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?
    • Palop JJ, Mucke L, (2010) Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? Neuromolecular Med 12: 48-55.
    • (2010) Neuromolecular Med , vol.12 , pp. 48-55
    • Palop, J.J.1    Mucke, L.2
  • 49
    • 84860151537 scopus 로고    scopus 로고
    • Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease
    • Lee SH, Kim KR, Ryu SY, Son S, Hong HS, et al. (2012) Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease. J Neurosci 32: 5953-5963.
    • (2012) J Neurosci , vol.32 , pp. 5953-5963
    • Lee, S.H.1    Kim, K.R.2    Ryu, S.Y.3    Son, S.4    Hong, H.S.5
  • 50
    • 79151475030 scopus 로고    scopus 로고
    • Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice
    • Gengler S, Hamilton A, Holscher C, (2010) Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice. PLoS One 5: e9764.
    • (2010) PLoS One , vol.5
    • Gengler, S.1    Hamilton, A.2    Holscher, C.3
  • 51
    • 70549106846 scopus 로고    scopus 로고
    • Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses
    • Abramov E, Dolev I, Fogel H, Ciccotosto GD, Ruff E, et al. (2009) Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci 12: 1567-1576.
    • (2009) Nat Neurosci , vol.12 , pp. 1567-1576
    • Abramov, E.1    Dolev, I.2    Fogel, H.3    Ciccotosto, G.D.4    Ruff, E.5
  • 52
    • 34548209899 scopus 로고    scopus 로고
    • The dentate gyrus as a filter or gate: a look back and a look ahead
    • Hsu D, (2007) The dentate gyrus as a filter or gate: a look back and a look ahead. Prog Brain Res 163: 601-613.
    • (2007) Prog Brain Res , vol.163 , pp. 601-613
    • Hsu, D.1
  • 53
    • 0343091552 scopus 로고    scopus 로고
    • Optical recording study of granule cell activities in the hippocampal dentate gyrus of kainate-treated rats
    • Otsu Y, Maru E, Ohata H, Takashima I, Kajiwara R, et al. (2000) Optical recording study of granule cell activities in the hippocampal dentate gyrus of kainate-treated rats. J Neurophysiol 83: 2421-2430.
    • (2000) J Neurophysiol , vol.83 , pp. 2421-2430
    • Otsu, Y.1    Maru, E.2    Ohata, H.3    Takashima, I.4    Kajiwara, R.5
  • 55
    • 31344432875 scopus 로고    scopus 로고
    • Epidemiological and medical aspects of epilepsy in the elderly
    • Cloyd J, Hauser W, Towne A, Ramsay R, Mattson R, et al. (2006) Epidemiological and medical aspects of epilepsy in the elderly. Epilepsy Res 68 Suppl 1: S39-48.
    • (2006) Epilepsy Res , vol.68 , Issue.SUPPL. 1
    • Cloyd, J.1    Hauser, W.2    Towne, A.3    Ramsay, R.4    Mattson, R.5
  • 56
    • 80051927442 scopus 로고    scopus 로고
    • Synapses, NMDA receptor activity and neuronal Abeta production in Alzheimer's disease
    • Bordji K, Becerril-Ortega J, Buisson A, (2011) Synapses, NMDA receptor activity and neuronal Abeta production in Alzheimer's disease. Rev Neurosci 22: 285-294.
    • (2011) Rev Neurosci , vol.22 , pp. 285-294
    • Bordji, K.1    Becerril-Ortega, J.2    Buisson, A.3
  • 57
    • 84862493307 scopus 로고    scopus 로고
    • New developments on the role of NMDA receptors in Alzheimer's disease
    • Malinow R (2011) New developments on the role of NMDA receptors in Alzheimer's disease. Curr Opin Neurobiol.
    • (2011) Curr Opin Neurobiol
    • Malinow, R.1
  • 58
    • 27744588007 scopus 로고    scopus 로고
    • Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
    • Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, et al. (2005) Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nat Neurosci 8: 1343-1349.
    • (2005) Nat Neurosci , vol.8 , pp. 1343-1349
    • Singer, O.1    Marr, R.A.2    Rockenstein, E.3    Crews, L.4    Coufal, N.G.5
  • 59
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh DM, Selkoe DJ, (2004) Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44: 181-193.
    • (2004) Neuron , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 60
    • 84873155644 scopus 로고    scopus 로고
    • Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures
    • Ferreira IL, Bajouco LM, Mota SI, Auberson YP, Oliveira CR, et al. (2011) Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures. Cell Calcium.
    • (2011) Cell Calcium
    • Ferreira, I.L.1    Bajouco, L.M.2    Mota, S.I.3    Auberson, Y.P.4    Oliveira, C.R.5
  • 61
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, et al. (2009) Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63: 178-188.
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1    Laviolette, P.S.2    O'Keefe, K.3    O'Brien, J.4    Rentz, D.M.5
  • 62
    • 80052563319 scopus 로고    scopus 로고
    • Neocortical excitation/inhibition balance in information processing and social dysfunction
    • Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, et al. (2011) Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 477: 171-178.
    • (2011) Nature , vol.477 , pp. 171-178
    • Yizhar, O.1    Fenno, L.E.2    Prigge, M.3    Schneider, F.4    Davidson, T.J.5
  • 63
    • 77954887426 scopus 로고    scopus 로고
    • The axon initial segment and the maintenance of neuronal polarity
    • Rasband MN, (2010) The axon initial segment and the maintenance of neuronal polarity. Nat Rev Neurosci 11: 552-562.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 552-562
    • Rasband, M.N.1
  • 65
    • 34249791771 scopus 로고    scopus 로고
    • Na(v)1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation
    • Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, et al. (2007) Na(v)1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J Neurosci 27: 5903-5914.
    • (2007) J Neurosci , vol.27 , pp. 5903-5914
    • Ogiwara, I.1    Miyamoto, H.2    Morita, N.3    Atapour, N.4    Mazaki, E.5
  • 66
    • 84878749435 scopus 로고    scopus 로고
    • BACE1 and presenilin/gamma-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels
    • Sachse CC, Kim YH, Agsten M, Huth T, Alzheimer C, et al. (2013) BACE1 and presenilin/gamma-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels. FASEB J.
    • (2013) FASEB J
    • Sachse, C.C.1    Kim, Y.H.2    Agsten, M.3    Huth, T.4    Alzheimer, C.5
  • 67
    • 84856328977 scopus 로고    scopus 로고
    • Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease
    • Thibault O, Pancani T, Landfield PW, Norris CM, (2012) Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease. Biochim Biophys Acta 1822: 546-549.
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 546-549
    • Thibault, O.1    Pancani, T.2    Landfield, P.W.3    Norris, C.M.4
  • 68
    • 84862261275 scopus 로고    scopus 로고
    • Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice
    • Chakroborty S, Kim J, Schneider C, Jacobson C, Molgo J, et al. (2012) Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice. J Neurosci 32: 8341-8353.
    • (2012) J Neurosci , vol.32 , pp. 8341-8353
    • Chakroborty, S.1    Kim, J.2    Schneider, C.3    Jacobson, C.4    Molgo, J.5
  • 69
    • 77952712188 scopus 로고    scopus 로고
    • The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner
    • Poulin B, Butcher A, McWilliams P, Bourgognon JM, Pawlak R, et al. (2010) The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner. Proc Natl Acad Sci U S A 107: 9440-9445.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9440-9445
    • Poulin, B.1    Butcher, A.2    McWilliams, P.3    Bourgognon, J.M.4    Pawlak, R.5
  • 70
    • 84858183199 scopus 로고    scopus 로고
    • Alzheimer's disease and epilepsy: insight from animal models
    • Scharfman HE, (2012) Alzheimer's disease and epilepsy: insight from animal models. Future Neurol 7: 177-192.
    • (2012) Future Neurol , vol.7 , pp. 177-192
    • Scharfman, H.E.1
  • 71
    • 84872080503 scopus 로고    scopus 로고
    • Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments
    • Culmone V, Migliore M, (2012) Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments. Front Comput Neurosci 6: 52.
    • (2012) Front Comput Neurosci , vol.6 , pp. 52
    • Culmone, V.1    Migliore, M.2
  • 72
    • 62249194824 scopus 로고    scopus 로고
    • Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease
    • Wilcock DM, Vitek MP, Colton CA, (2009) Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. Neuroscience 159: 1055-1069.
    • (2009) Neuroscience , vol.159 , pp. 1055-1069
    • Wilcock, D.M.1    Vitek, M.P.2    Colton, C.A.3
  • 73
    • 84860151537 scopus 로고    scopus 로고
    • Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease
    • Lee SH, Kim KR, Ryu SY, Son S, Hong HS, et al. (2012) Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease. J Neurosci 32: 5953-5963.
    • (2012) J Neurosci , vol.32 , pp. 5953-5963
    • Lee, S.H.1    Kim, K.R.2    Ryu, S.Y.3    Son, S.4    Hong, H.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.