-
1
-
-
0033599038
-
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL, Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O'Rahilly S (1999) Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402:880-883
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
Agostini, M.4
Schwabe, J.W.5
Soos, M.A.6
Maslen, G.L.7
Williams, T.D.8
Lewis, H.9
Schafer, A.J.10
Chatterjee, V.K.11
O'Rahilly, S.12
-
2
-
-
0029745382
-
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: Binding and activation correlate with antidiabetic actions in db/db mice
-
Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG, Leibowitz MD (1996) Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137:4189-4195
-
(1996)
Endocrinology
, vol.137
, pp. 4189-4195
-
-
Berger, J.1
Bailey, P.2
Biswas, C.3
Cullinan, C.A.4
Doebber, T.W.5
Hayes, N.S.6
Saperstein, R.7
Smith, R.G.8
Leibowitz, M.D.9
-
3
-
-
0029550376
-
Long-term effects of fluoxetine on glycemic control in obese patients with non-insulin-dependent diabetes mellitus or glucose intolerance: Influence on muscle glycogen synthase and insulin receptor kinase activity
-
Breum L, Bjerre U, Bak JF, Jacobsen S, Astrup A (1995) Long-term effects of fluoxetine on glycemic control in obese patients with non-insulin-dependent diabetes mellitus or glucose intolerance: influence on muscle glycogen synthase and insulin receptor kinase activity. Metabolism 44:1570-1576
-
(1995)
Metabolism
, vol.44
, pp. 1570-1576
-
-
Breum, L.1
Bjerre, U.2
Bak, J.F.3
Jacobsen, S.4
Astrup, A.5
-
5
-
-
0032846879
-
Mechanism of fluoxetine block of cloned voltage-activated potassium channel Kv1.3
-
Choi JS, Hahn SJ, Rhie DJ, Yoon SH, Jo YH, Kim MS (1999) Mechanism of fluoxetine block of cloned voltage-activated potassium channel Kv1.3. J Pharmacol Exp Ther 291:1-6
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1-6
-
-
Choi, J.S.1
Hahn, S.J.2
Rhie, D.J.3
Yoon, S.H.4
Jo, Y.H.5
Kim, M.S.6
-
6
-
-
0031928230
-
Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance
-
Dal Ponte DB, Fogt DL, Jacob S, Henriksen EJ (1998) Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance. Metabolism 47:982-987
-
(1998)
Metabolism
, vol.47
, pp. 982-987
-
-
Dal Ponte, D.B.1
Fogt, D.L.2
Jacob, S.3
Henriksen, E.J.4
-
7
-
-
0030768949
-
Block of human cardiac Kv1.5 channels by loratadine: Voltage-, time- and use-dependent block at concentrations above therapeutic levels
-
Delpon E, Valenzuela C, Gay P, Franqueza L, Snyders DJ, Tamargo J (1997) Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels. Cardiovasc Res 35:341-350
-
(1997)
Cardiovasc Res
, vol.35
, pp. 341-350
-
-
Delpon, E.1
Valenzuela, C.2
Gay, P.3
Franqueza, L.4
Snyders, D.J.5
Tamargo, J.6
-
8
-
-
0035967936
-
Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle
-
Eto K, Ohya Y, Nakamura Y, Abe I, Fujishima M (2001) Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. Eur J Pharmacol 423:1-7
-
(2001)
Eur J Pharmacol
, vol.423
, pp. 1-7
-
-
Eto, K.1
Ohya, Y.2
Nakamura, Y.3
Abe, I.4
Fujishima, M.5
-
9
-
-
0030438721
-
Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, with an animal scale-up approach
-
Izumi T, Enomoto S, Hosiyama K, Sasahara K, Shibukawa A, Nakagawa T, Sugiyama Y (1996) Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, with an animal scale-up approach. J Pharmacol Exp Ther 277:1630-1641
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 1630-1641
-
-
Izumi, T.1
Enomoto, S.2
Hosiyama, K.3
Sasahara, K.4
Shibukawa, A.5
Nakagawa, T.6
Sugiyama, Y.7
-
10
-
-
0033004825
-
Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes
-
Knock GA, Mishra SK, Aaronson PI (1999) Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes. Eur J Pharmacol 368:103-109
-
(1999)
Eur J Pharmacol
, vol.368
, pp. 103-109
-
-
Knock, G.A.1
Mishra, S.K.2
Aaronson, P.I.3
-
11
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
13
-
-
0347785490
-
+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion
-
+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion. J Biol Chem 277:44938-44945
-
(2002)
J Biol Chem
, vol.277
, pp. 44938-44945
-
-
MacDonald, P.E.1
Sewing, S.2
Wang, J.3
Joseph, J.W.4
Smukler, S.R.5
Sakellaropoulos, G.6
Wang, J.7
Saleh, M.C.8
Chan, C.B.9
Tsushima, R.G.10
Salapatek, A.M.11
Wheeler, M.B.12
-
14
-
-
10544227302
-
+ channels. Role in stimulus-secretion coupling
-
+ channels. Role in stimulus-secretion coupling. J Biol Chem 271:32241-32246
-
(1996)
J Biol Chem
, vol.271
, pp. 32241-32246
-
-
Roe, M.W.1
Worley III, J.F.2
Mittal, A.A.3
Kuznetsov, A.4
DasGupta, S.5
Mertz, R.J.6
Witherspoon III, S.M.7
Blair, N.8
Lancaster, M.E.9
McIntyre, M.S.10
Shehee, W.R.11
Dukes, I.D.12
Philipson, L.H.13
-
15
-
-
0029130666
-
Determinants of antiarrhythmic drug action. Electrostatic and hydrophobic components of block of the human cardiac hKv1.5 channel
-
Snyders DJ, Yeola SW (1995) Determinants of antiarrhythmic drug action. Electrostatic and hydrophobic components of block of the human cardiac hKv1.5 channel. Circ Res 77:575-583
-
(1995)
Circ Res
, vol.77
, pp. 575-583
-
-
Snyders, D.J.1
Yeola, S.W.2
-
16
-
-
0029790924
-
Class III antiarrhythmic effects of zatebradine. Time-, state-, use-, and voltage-dependent block of hKv1.5 channels
-
Valenzuela C, Delpon E, Franqueza L, Gay P, Perez O, Tamargo J, Snyders DJ (1996) Class III antiarrhythmic effects of zatebradine. Time-, state-, use-, and voltage-dependent block of hKv1.5 channels. Circulation 94:562-570
-
(1996)
Circulation
, vol.94
, pp. 562-570
-
-
Valenzuela, C.1
Delpon, E.2
Franqueza, L.3
Gay, P.4
Perez, O.5
Tamargo, J.6
Snyders, D.J.7
-
17
-
-
0036343675
-
Rosiglitazone: A review of its use in the management of type 2 diabetes mellitus
-
Wagstaff AJ, Goa KL (2002) Rosiglitazone: a review of its use in the management of type 2 diabetes mellitus. Drugs 62:1805-1837
-
(2002)
Drugs
, vol.62
, pp. 1805-1837
-
-
Wagstaff, A.J.1
Goa, K.L.2
-
18
-
-
0030062325
-
The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
-
Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM (1996) The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 39:665-668
-
(1996)
J Med Chem
, vol.39
, pp. 665-668
-
-
Willson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
Wiethe, R.W.4
Correa, I.D.5
Prakash, S.R.6
Beck, K.D.7
Moore, L.B.8
Kliewer, S.A.9
Lehmann, J.M.10
-
19
-
-
1542357667
-
The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity
-
Xu J, Wang P, Li Y, Li G, Kaczmarek LK, Wu Y, Koni PA, Flavell RA, Desir GV (2004) The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity. Proc Natl Acad Sci USA 101:3112-3117
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3112-3117
-
-
Xu, J.1
Wang, P.2
Li, Y.3
Li, G.4
Kaczmarek, L.K.5
Wu, Y.6
Koni, P.A.7
Flavell, R.A.8
Desir, G.V.9
|