Evaluation of the efficiency of human immune system reconstitution in NSG mice and NSG mice containing a human HLA.A2 transgene using hematopoietic stem cells purified from different sources

Journal of Immunological Methods

Volumn 422, Issue , 2015, Pages 13-21

  Patton, John ^a   Vuyyuru, Raja ^a   Siglin, Amanda ^a   Root, Michael ^a   Manser, Tim ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Hematopoietic stem cells; HLA A2 transgene; Humanized mice

Indexed keywords

CD3 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; HLA A2 ANTIGEN; PTPRC PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL SUSPENSION; CONTROLLED STUDY; DISEASE MODEL; FETUS; FETUS LIVER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE SYSTEM RECONSTITUTION; IMMUNOLOGICAL PROCEDURES; INTESTINE LYMPHATIC TISSUE; LYMPHOID PROGENITOR CELL; MACROPHAGE; MONOCYTE; MOUSE; NATURAL KILLER CELL; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSGENE; UMBILICAL CORD BLOOD; ANIMAL; CHIMERA; CYTOLOGY; FETUS BLOOD; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; KNOCKOUT MOUSE; LIVER; METABOLISM; NONOBESE DIABETIC MOUSE; SCID MOUSE; XENOGRAFT;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ANIMALS; ANTIGENS, CD34; ANTIGENS, CD45; CHIMERA; FETAL BLOOD; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HLA-A2 ANTIGEN; HUMANS; LIVER; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; TRANSPLANTATION, HETEROLOGOUS;

EID: 84930767744     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2015.02.007     Document Type: Article

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