Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2rγnull humanized mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 29, 2010, Pages 13022-13027

  Shultz, Leonard D ^a   Saito, Yoriko ^b   Najima, Yuho ^b   Tanaka, Satoshi ^c   Ochi, Toshiki ^d   Tomizawa, Mariko ^b   Doi, Takehiko ^b   Sone, Akiko ^b   Suzuki, Nahoko ^b   Fujiwara, Hiroshi ^d   Yasukawa, Masaki ^d   Ishikawa, Fumihiko ^b  

^a JACKSON LABORATORY   (United States)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c Nippon Becton Dickinson   (Japan)

^d EHIME UNIVERSITY   (Japan)

Author keywords

Epstein Barr virus; HLA restriction; Human immunology; T cell development

Indexed keywords

HLA ANTIGEN CLASS 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS INFECTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL;

ANIMALS; ANIMALS, NEWBORN; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CYTOTOXICITY, IMMUNOLOGIC; EPSTEIN-BARR VIRUS INFECTIONS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HERPESVIRUS 4, HUMAN; HLA-A2 ANTIGEN; HUMANS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; MICE; MICE, INBRED NOD; MICE, SCID; SPECIES SPECIFICITY; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC;

HUMAN HERPESVIRUS 4; MUS;

EID: 77955599615     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1000475107     Document Type: Article

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