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Volumn 12, Issue 107, 2015, Pages

Semi-adaptive response and noise attenuation in bone morphogenetic protein signalling

Author keywords

Activation time; Adaptive response; Negative feedback; Noise attenuation; Response speed; Smad phosphorylation

Indexed keywords

BONE; CHEMICAL ACTIVATION; ECONOMIC AND SOCIAL EFFECTS; ENZYME ACTIVITY; PHOSPHORYLATION; PROTEINS;

EID: 84930707383     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2015.0258     Document Type: Article
Times cited : (3)

References (40)
  • 1
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BL. 1996 Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10, 1580-1594. (doi:10.1101/gad.10.13.1580)
    • (1996) Genes Dev. , vol.10 , pp. 1580-1594
    • Hogan, B.L.1
  • 2
    • 0030792319 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in the nervous system
    • Mehler MF, Mabie PC, Zhang D, Kessler JA. 1997 Bone morphogenetic proteins in the nervous system. Trends Neurosci. 20, 309-317. (doi:10.1016/S0166-2236(96)01046-6)
    • (1997) Trends Neurosci. , vol.20 , pp. 309-317
    • Mehler, M.F.1    Mabie, P.C.2    Zhang, D.3    Kessler, J.A.4
  • 3
    • 28944448921 scopus 로고    scopus 로고
    • Molecular genetics of axis formation in zebrafish
    • Schier AF, Talbot WS. 2005 Molecular genetics of axis formation in zebrafish. Annu. Rev. Genet. 39, 561-613. (doi:10.1146/annurev.genet.37.110801.143752)
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 561-613
    • Schier, A.F.1    Talbot, W.S.2
  • 4
    • 0026451642 scopus 로고
    • Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo
    • Ferguson EL, Anderson KV. 1992 Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461. (doi:10.1016/0092-8674(92)90514-D)
    • (1992) Cell , vol.71 , pp. 451-461
    • Ferguson, E.L.1    Anderson, K.V.2
  • 5
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • Shi Y, Massague J. 2003 Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113, 685-700. (doi:10.1016/S0092-8674(03)00432-X)
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 6
    • 27644494876 scopus 로고    scopus 로고
    • Smad transcription factors
    • Massague J, Seoane J, Wotton D. 2005 Smad transcription factors. Genes Dev. 19, 2783-2810. (doi:10.1101/gad.1350705)
    • (2005) Genes Dev. , vol.19 , pp. 2783-2810
    • Massague, J.1    Seoane, J.2    Wotton, D.3
  • 7
    • 33846011104 scopus 로고    scopus 로고
    • Regulation of Smad activities
    • Xu L. 2006 Regulation of Smad activities. Biochim. Biophys. Acta 1759, 503-513. (doi:10.1016/j.bbaexp.2006.11.001)
    • (2006) Biochim. Biophys. Acta , vol.1759 , pp. 503-513
    • Xu, L.1
  • 8
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-β signaling through Smads
    • Feng X-H, Derynck R. 2005 Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693. (doi:10.1146/annurev.cellbio.21.022404.142018)
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 659-693
    • Feng, X.-H.1    Derynck, R.2
  • 9
    • 33846688094 scopus 로고    scopus 로고
    • Balancing BMP signaling through integrated inputs into the Smad1 linker
    • Sapkota G, Alarcon C, Spagnoli FM, Brivanlou AH, Massague J. 2007 Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol. Cell 25, 441-454. (doi:10.1016/j.molcel.2007.01.006)
    • (2007) Mol. Cell , vol.25 , pp. 441-454
    • Sapkota, G.1    Alarcon, C.2    Spagnoli, F.M.3    Brivanlou, A.H.4    Massague, J.5
  • 10
    • 33747044916 scopus 로고    scopus 로고
    • Unique players in the BMP pathway: Small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling
    • Knockaert M, Sapkota G, Alarcon C, Massague J, Brivanlou AH. 2006 Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proc. Natl Acad. Sci. USA 103, 11 940-11 945. (doi:10.1073/pnas.0605133103)
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.11 , pp. 940-11945
    • Knockaert, M.1    Sapkota, G.2    Alarcon, C.3    Massague, J.4    Brivanlou, A.H.5
  • 11
    • 33747053414 scopus 로고    scopus 로고
    • Central roles of the roof plate in telencephalic development and holoprosencephaly
    • Cheng X, Hsu C-M, Currle DS, Hu JS, Barkovich AJ, Monuki ES. 2006 Central roles of the roof plate in telencephalic development and holoprosencephaly. J. Neurosci. 26, 7640-7649. (doi:10.1523/JNEUROSCI.0714-06.2006)
    • (2006) J. Neurosci. , vol.26 , pp. 7640-7649
    • Cheng, X.1    Hsu, C.-M.2    Currle, D.S.3    Hu, J.S.4    Barkovich, A.J.5    Monuki, E.S.6
  • 13
    • 84856094426 scopus 로고    scopus 로고
    • Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube
    • Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V. 2012 Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell 148, 273-284. (doi:10.1016/j.cell.2011.10.047)
    • (2012) Cell , vol.148 , pp. 273-284
    • Balaskas, N.1    Ribeiro, A.2    Panovska, J.3    Dessaud, E.4    Sasai, N.5    Page, K.M.6    Briscoe, J.7    Ribes, V.8
  • 14
    • 84876294515 scopus 로고    scopus 로고
    • Visualization of an endogenous retinoic acid gradient across embryonic development
    • Shimozono S, Iimura T, Kitaguchi T, Higashijima S-I, Miyawaki A. 2013 Visualization of an endogenous retinoic acid gradient across embryonic development. Nature 496, 363-366. (doi:10.1038/nature12037)
    • (2013) Nature , vol.496 , pp. 363-366
    • Shimozono, S.1    Iimura, T.2    Kitaguchi, T.3    Higashijima, S.-I.4    Miyawaki, A.5
  • 15
    • 84872662531 scopus 로고    scopus 로고
    • Dynamics and precision in retinoic acid morphogen gradients
    • Schilling TF, Nie Q, Lander AD. 2012 Dynamics and precision in retinoic acid morphogen gradients. Curr. Opin. Genet. Dev. 22, 562-569. (doi:10.1016/j.gde.2012.11.012.Dynamics)
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 562-569
    • Schilling, T.F.1    Nie, Q.2    Lander, A.D.3
  • 16
    • 84866977110 scopus 로고    scopus 로고
    • Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain
    • Zhang L, Radtke K, Zheng L, Cai AQ, Schilling TF, Nie Q. 2012 Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain. Mol. Syst. Biol. 8, 613. (doi:10.1038/msb.2012.45)
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 613
    • Zhang, L.1    Radtke, K.2    Zheng, L.3    Cai, A.Q.4    Schilling, T.F.5    Nie, Q.6
  • 18
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-βsignaling
    • Massague J, Chen YG. 2000 Controlling TGF-βsignaling. Genes Dev. 14, 627-644. (doi:10.1101/gad.14.6.627)
    • (2000) Genes Dev. , vol.14 , pp. 627-644
    • Massague, J.1    Chen, Y.G.2
  • 19
    • 84893359901 scopus 로고    scopus 로고
    • Characterization of negative feedback network motifs in the TGF-β signaling pathway
    • Nicklas D, Saiz L. 2013 Characterization of negative feedback network motifs in the TGF-β signaling pathway. PLoS ONE 8, e83531. (doi:10.1371/journal.pone.0083531)
    • (2013) PLoS ONE , vol.8
    • Nicklas, D.1    Saiz, L.2
  • 20
    • 84892594912 scopus 로고    scopus 로고
    • Role of miR-17 family in the negative feedback loop of bone morphogenetic protein signaling in neuron
    • Sun Q, Mao S, Li H, Zen K, Zhang C-Y, Li L. 2013 Role of miR-17 family in the negative feedback loop of bone morphogenetic protein signaling in neuron. PLoS ONE 8, e83067. (doi:10.1371/journal.pone.0083067)
    • (2013) PLoS ONE , vol.8
    • Sun, Q.1    Mao, S.2    Li, H.3    Zen, K.4    Zhang, C.-Y.5    Li, L.6
  • 21
    • 0029267491 scopus 로고
    • Dynamical behaviour of biological regulatory networks - I. Biological role of feedback loops and practical use of the concept of the loop-characteristic state
    • Thomas R, Thieffry D, Kaufman M. 1995 Dynamical behaviour of biological regulatory networks - I. Biological role of feedback loops and practical use of the concept of the loop-characteristic state. Bull. Math. Biol. 57, 247-276. (doi:10.1007/BF02460618)
    • (1995) Bull. Math. Biol. , vol.57 , pp. 247-276
    • Thomas, R.1    Thieffry, D.2    Kaufman, M.3
  • 23
    • 84895746496 scopus 로고    scopus 로고
    • A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain
    • Srinivasan S, Hu JS, Currle DS, Fung ES, Hayes WB, Lander AD, Monuki ES. 2014 A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain. PLoS Comput. Biol. 10, e1003463. (doi:10.1371/journal.pcbi.1003463)
    • (2014) PLoS Comput. Biol. , vol.10
    • Srinivasan, S.1    Hu, J.S.2    Currle, D.S.3    Fung, E.S.4    Hayes, W.B.5    Lander, A.D.6    Monuki, E.S.7
  • 24
    • 77954566837 scopus 로고    scopus 로고
    • A critical quantity for noise attenuation in feedback systems
    • Wang L, Xin J, Nie Q. 2010 A critical quantity for noise attenuation in feedback systems. PLoS Comput. Biol. 6, e1000764. (doi:10.1371/journal.pcbi.1000764)
    • (2010) PLoS Comput. Biol. , vol.6
    • Wang, L.1    Xin, J.2    Nie, Q.3
  • 25
    • 84886449631 scopus 로고    scopus 로고
    • Noise attenuation in the ON and OFF states of biological switches
    • Chen M, Wang L, Liu CC, Nie Q. 2013 Noise attenuation in the ON and OFF states of biological switches. ACS Synth. Biol. 2, 587-593. (doi:10.1021/sb400044g)
    • (2013) ACS Synth. Biol. , vol.2 , pp. 587-593
    • Chen, M.1    Wang, L.2    Liu, C.C.3    Nie, Q.4
  • 26
    • 70350780570 scopus 로고    scopus 로고
    • Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways
    • Alarcon C et al. 2009 Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways. Cell 139, 757-769. (doi:10.1016/j.cell.2009.09.035)
    • (2009) Cell , vol.139 , pp. 757-769
    • Alarcon, C.1
  • 27
    • 65549170041 scopus 로고    scopus 로고
    • Quantitative modeling and analysis of the transforming growth factor β signaling pathway
    • Chung S-W, Miles FL, Sikes RA, Cooper CR, Farach-Carson MC, Ogunnaike BA. 2009 Quantitative modeling and analysis of the transforming growth factor β signaling pathway. Biophys. J. 96, 1733-1750. (doi:10.1016/j.bpj.2008.11.050)
    • (2009) Biophys. J. , vol.96 , pp. 1733-1750
    • Chung, S.-W.1    Miles, F.L.2    Sikes, R.A.3    Cooper, C.R.4    Farach-Carson, M.C.5    Ogunnaike, B.A.6
  • 28
    • 67349239782 scopus 로고    scopus 로고
    • A mathematical model of the stoichiometric control of Smad complex formation in TGF-β signal transduction pathway
    • Nakabayashi J, Sasaki A. 2009 A mathematical model of the stoichiometric control of Smad complex formation in TGF-β signal transduction pathway. J. Theor. Biol. 259, 389-403. (doi:10.1016/j.jtbi.2009.03.036)
    • (2009) J. Theor. Biol. , vol.259 , pp. 389-403
    • Nakabayashi, J.1    Sasaki, A.2
  • 29
    • 44349125602 scopus 로고    scopus 로고
    • Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
    • Schmierer B, Tournier AL, Bates PA, Hill CS. 2008 Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system. Proc. Natl Acad. Sci. USA 105, 6608-6613. (doi:10.1073/pnas.0710134105)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 6608-6613
    • Schmierer, B.1    Tournier, A.L.2    Bates, P.A.3    Hill, C.S.4
  • 30
    • 84860765696 scopus 로고    scopus 로고
    • Secreted, receptor-associated bone morphogenetic protein regulators reduce stochastic noise intrinsic to many extracellular morphogen distributions
    • Karim MS, Buzzard GT, Umulis DM. 2012 Secreted, receptor-associated bone morphogenetic protein regulators reduce stochastic noise intrinsic to many extracellular morphogen distributions. J. R. Soc. Interface 9, 1073-1083. (doi:10.1098/rsif.2011.0547)
    • (2012) J. R. Soc. Interface , vol.9 , pp. 1073-1083
    • Karim, M.S.1    Buzzard, G.T.2    Umulis, D.M.3
  • 31
    • 33645754505 scopus 로고    scopus 로고
    • Signal processing in the TGF-β superfamily ligand-receptor network
    • Vilar JMG, Jansen R, Sander C. 2006 Signal processing in the TGF-β superfamily ligand-receptor network. PLoS Comput. Biol. 2, e3. (doi:10.1371/journal.pcbi.0020003)
    • (2006) PLoS Comput. Biol. , vol.2 , pp. e3
    • Vilar, J.M.G.1    Jansen, R.2    Sander, C.3
  • 32
    • 84879812351 scopus 로고    scopus 로고
    • Tunable signal processing through a kinase control cycle: The IKK signaling node
    • Behar M, Hoffmann A. 2013 Tunable signal processing through a kinase control cycle: the IKK signaling node. Biophys. J. 105, 231-241. (doi:10.1016/j.bpj.2013.05.013)
    • (2013) Biophys. J. , vol.105 , pp. 231-241
    • Behar, M.1    Hoffmann, A.2
  • 33
    • 84885669414 scopus 로고    scopus 로고
    • The dynamics of signaling as a pharmacological target
    • Behar M, Barken D, Werner SL, Hoffmann A. 2013 The dynamics of signaling as a pharmacological target. Cell 155, 448-461. (doi:10.1016/j.cell.2013.09.018)
    • (2013) Cell , vol.155 , pp. 448-461
    • Behar, M.1    Barken, D.2    Werner, S.L.3    Hoffmann, A.4
  • 34
    • 0036428761 scopus 로고    scopus 로고
    • Negative autoregulation speeds the response times of transcription networks
    • Rosenfeld N, Elowitz MB, Alon U. 2002 Negative autoregulation speeds the response times of transcription networks. J. Mol. Biol. 323, 785-793. (doi:10.1016/S0022-2836(02)00994-4)
    • (2002) J. Mol. Biol. , vol.323 , pp. 785-793
    • Rosenfeld, N.1    Elowitz, M.B.2    Alon, U.3
  • 35
    • 0037376655 scopus 로고    scopus 로고
    • Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell
    • Tyson JJ, Chen KC, Novak B. 2003 Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr. Opin. Cell Biol. 15, 221-231. (doi:10.1016/S0955-0674(03)00017-6)
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 221-231
    • Tyson, J.J.1    Chen, K.C.2    Novak, B.3
  • 36
    • 0016145568 scopus 로고
    • Comparison of classical and autogenous systems of regulation in inducible operons
    • Savageau MA. 1974 Comparison of classical and autogenous systems of regulation in inducible operons. Nature 252, 546-549. (doi:10.1038/252546a0)
    • (1974) Nature , vol.252 , pp. 546-549
    • Savageau, M.A.1
  • 37
    • 0038392724 scopus 로고    scopus 로고
    • Response delays and the structure of transcription networks
    • Rosenfeld N, Alon U. 2003 Response delays and the structure of transcription networks. J. Mol. Biol. 329, 645-654. (doi:10.1016/S0022-2836(03)00506-0)
    • (2003) J. Mol. Biol. , vol.329 , pp. 645-654
    • Rosenfeld, N.1    Alon, U.2
  • 38
    • 0029099367 scopus 로고
    • Direct and continuous assessment by cells of their position in a morphogen gradient
    • Gurdon JB, Mitchell A, Mahony D. 1995 Direct and continuous assessment by cells of their position in a morphogen gradient. Nature 376, 520-521. (doi:10.1038/376520a0)
    • (1995) Nature , vol.376 , pp. 520-521
    • Gurdon, J.B.1    Mitchell, A.2    Mahony, D.3
  • 39
    • 0032524323 scopus 로고    scopus 로고
    • The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
    • Dyson S, Gurdon JB. 1998 The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 93, 557-568. (doi:10.1016/S0092-8674(00)81185-X)
    • (1998) Cell , vol.93 , pp. 557-568
    • Dyson, S.1    Gurdon, J.B.2
  • 40
    • 27744506127 scopus 로고    scopus 로고
    • Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction
    • Jullien J, Gurdon J. 2005 Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction. Genes Dev. 19, 2682-2694. (doi:10.1101/gad.341605)
    • (2005) Genes Dev. , vol.19 , pp. 2682-2694
    • Jullien, J.1    Gurdon, J.2


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