A mathematical model of the stoichiometric control of Smad complex formation in TGF-β signal transduction pathway

Journal of Theoretical Biology

Volumn 259, Issue 2, 2009, Pages 389-403

  Nakabayashi, Jun ^a   Sasaki, Akira ^a,b,c  

^a GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^b INTERNATIONAL INSTITUTE FOR APPLIED SYSTEMS ANALYSIS   (Austria)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Signal transduction; Smad; Stoichiometry of oligomers; Transcriptional complex formation

Indexed keywords

RECEPTOR REGULATED SMAD PROTEIN; SMAD PROTEIN; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

CONCENTRATION (COMPOSITION); CYTOLOGY; NUMERICAL MODEL; PROTEIN; SIGNALING; STOICHIOMETRY;

ANALYTIC METHOD; ARTICLE; CELL COMPARTMENTALIZATION; CELL NUCLEUS; COMPARTMENT MODEL; COMPLEX FORMATION; CYTOPLASM; DIMERIZATION; DISSOCIATION; ENDOTHELIUM CELL; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STOICHIOMETRY;

ANIMALS; CELL NUCLEUS; CYTOPLASM; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 67349239782     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2009.03.036     Document Type: Article

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