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Volumn 148, Issue 1-2, 2012, Pages 273-284

Gene regulatory logic for reading the sonic hedgehog signaling gradient in the vertebrate neural tube

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR;

EID: 84856094426     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.10.047     Document Type: Article
Times cited : (356)

References (72)
  • 1
    • 4043122029 scopus 로고    scopus 로고
    • Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning
    • DOI 10.1016/j.cell.2004.07.023, PII S0092867404007111
    • S. Ahn, and A.L. Joyner Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning Cell 118 2004 505 516 (Pubitemid 39485669)
    • (2004) Cell , vol.118 , Issue.4 , pp. 505-516
    • Ahn, S.1    Joyner, A.L.2
  • 2
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: Theory and experimental approaches
    • DOI 10.1038/nrg2102, PII NRG2102
    • U. Alon Network motifs: theory and experimental approaches Nat. Rev. Genet. 8 2007 450 461 (Pubitemid 46789247)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.6 , pp. 450-461
    • Alon, U.1
  • 5
    • 0033560895 scopus 로고    scopus 로고
    • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
    • DOI 10.1038/19315
    • J. Briscoe, L. Sussel, P. Serup, D. Hartigan-O'Connor, T.M. Jessell, J.L. Rubenstein, and J. Ericson Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling Nature 398 1999 622 627 (Pubitemid 29183690)
    • (1999) Nature , vol.398 , Issue.6728 , pp. 622-627
    • Briscoe, J.1    Sussel, L.2    Serup, P.3    Hartigan-O'Connor, D.4    Jessell, T.M.5    Rubenstein, J.L.R.6    Ericson, J.7
  • 6
    • 0034640087 scopus 로고    scopus 로고
    • A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
    • J. Briscoe, A. Pierani, T.M. Jessell, and J. Ericson A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube Cell 101 2000 435 445
    • (2000) Cell , vol.101 , pp. 435-445
    • Briscoe, J.1    Pierani, A.2    Jessell, T.M.3    Ericson, J.4
  • 7
    • 42549109108 scopus 로고    scopus 로고
    • Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning
    • DOI 10.1242/dev.013086
    • C.E. Chamberlain, J. Jeong, C. Guo, B.L. Allen, and A.P. McMahon Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning Development 135 2008 1097 1106 (Pubitemid 351578138)
    • (2008) Development , vol.135 , Issue.6 , pp. 1097-1106
    • Chamberlain, C.E.1    Jeong, J.2    Guo, C.3    Allen, B.L.4    McMahon, A.P.5
  • 8
    • 0030297553 scopus 로고    scopus 로고
    • Dual roles for patched in sequestering and transducing Hedgehog
    • DOI 10.1016/S0092-8674(00)81374-4
    • Y. Chen, and G. Struhl Dual roles for patched in sequestering and transducing Hedgehog Cell 87 1996 553 563 (Pubitemid 26374328)
    • (1996) Cell , vol.87 , Issue.3 , pp. 553-563
    • Chen, Y.1    Struhl, G.2
  • 9
    • 0034696445 scopus 로고    scopus 로고
    • How to make a biological switch
    • DOI 10.1006/jtbi.2000.1068
    • J.L. Cherry, and F.R. Adler How to make a biological switch J. Theor. Biol. 203 2000 117 133 (Pubitemid 30662944)
    • (2000) Journal of Theoretical Biology , vol.203 , Issue.2 , pp. 117-133
    • Cherry, J.L.1    Adler, F.R.2
  • 10
    • 0032486433 scopus 로고    scopus 로고
    • Teratogen-mediated inhibition of target tissue response to Shh signaling
    • DOI 10.1126/science.280.5369.1603
    • M.K. Cooper, J.A. Porter, K.E. Young, and P.A. Beachy Teratogen-mediated inhibition of target tissue response to Shh signaling Science 280 1998 1603 1607 (Pubitemid 28277705)
    • (1998) Science , vol.280 , Issue.5369 , pp. 1603-1607
    • Cooper, M.K.1    Porter, J.A.2    Young, K.E.3    Beachy, P.A.4
  • 11
    • 0033453239 scopus 로고    scopus 로고
    • Attenuation of green fluorescent protein half-life in mammalian cells
    • P. Corish, and C. Tyler-Smith Attenuation of green fluorescent protein half-life in mammalian cells Protein Eng. 12 1999 1035 1040 (Pubitemid 30011478)
    • (1999) Protein Engineering , vol.12 , Issue.12 , pp. 1035-1040
    • Corish, P.1    Tyler-Smith, C.2
  • 12
    • 78650362376 scopus 로고    scopus 로고
    • Emerging properties of animal gene regulatory networks
    • E.H. Davidson Emerging properties of animal gene regulatory networks Nature 468 2010 911 920
    • (2010) Nature , vol.468 , pp. 911-920
    • Davidson, E.H.1
  • 13
    • 58149481232 scopus 로고    scopus 로고
    • Properties of developmental gene regulatory networks
    • E.H. Davidson, and M.S. Levine Properties of developmental gene regulatory networks Proc. Natl. Acad. Sci. USA 105 2008 20063 20066
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 20063-20066
    • Davidson, E.H.1    Levine, M.S.2
  • 14
    • 36749092279 scopus 로고    scopus 로고
    • Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
    • DOI 10.1038/nature06347, PII NATURE06347
    • E. Dessaud, L.L. Yang, K. Hill, B. Cox, F. Ulloa, A. Ribeiro, A. Mynett, B.G. Novitch, and J. Briscoe Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism Nature 450 2007 717 720 (Pubitemid 350207693)
    • (2007) Nature , vol.450 , Issue.7170 , pp. 717-720
    • Dessaud, E.1    Yang, L.L.2    Hill, K.3    Cox, B.4    Ulloa, F.5    Ribeiro, A.6    Mynett, A.7    Novitch, B.G.8    Briscoe, J.9
  • 16
    • 0024323615 scopus 로고
    • Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen
    • DOI 10.1038/340363a0
    • W. Driever, G. Thoma, and C. Nüsslein-Volhard Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen Nature 340 1989 363 367 (Pubitemid 19191601)
    • (1989) Nature , vol.340 , Issue.6232 , pp. 363-367
    • Driever, W.1    Thoma, G.2    Nusslein-Volhard, C.3
  • 17
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • DOI 10.1038/35002125
    • M.B. Elowitz, and S. Leibler A synthetic oscillatory network of transcriptional regulators Nature 403 2000 335 338 (Pubitemid 30062393)
    • (2000) Nature , vol.403 , Issue.6767 , pp. 335-338
    • Elowitz, M.B.1    Leibier, S.2
  • 18
    • 0031458813 scopus 로고    scopus 로고
    • Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
    • DOI 10.1016/S0092-8674(00)80323-2
    • J. Ericson, P. Rashbass, A. Schedl, S. Brenner-Morton, A. Kawakami, V. van Heyningen, T.M. Jessell, and J. Briscoe Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling Cell 90 1997 169 180 (Pubitemid 28009428)
    • (1997) Cell , vol.90 , Issue.1 , pp. 169-180
    • Ericson, J.1    Rashbass, P.2    Schedl, A.3    Brenner-Morton, S.4    Kawakami, A.5    Van Heyningen, V.6    Jessell, T.M.7    Briscoe, J.8
  • 19
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • DOI 10.1126/science.277.5329.1109
    • L.V. Goodrich, L. Milenković, K.M. Higgins, and M.P. Scott Altered neural cell fates and medulloblastoma in mouse patched mutants Science 277 1997 1109 1113 (Pubitemid 27371635)
    • (1997) Science , vol.277 , Issue.5329 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3    Scott, M.P.4
  • 20
    • 34447099234 scopus 로고    scopus 로고
    • Probing the Limits to Positional Information
    • DOI 10.1016/j.cell.2007.05.025, PII S0092867407006629
    • T. Gregor, D.W. Tank, E.F. Wieschaus, and W. Bialek Probing the limits to positional information Cell 130 2007 153 164 (Pubitemid 47031318)
    • (2007) Cell , vol.130 , Issue.1 , pp. 153-164
    • Gregor, T.1    Tank, D.W.2    Wieschaus, E.F.3    Bialek, W.4
  • 21
    • 77954632586 scopus 로고    scopus 로고
    • Modelling the Bicoid gradient
    • O. Grimm, M. Coppey, and E. Wieschaus Modelling the Bicoid gradient Development 137 2010 2253 2264
    • (2010) Development , vol.137 , pp. 2253-2264
    • Grimm, O.1    Coppey, M.2    Wieschaus, E.3
  • 22
    • 4644328190 scopus 로고    scopus 로고
    • Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities
    • DOI 10.1016/j.cell.2004.07.024, PII S0092867404007123
    • B.D. Harfe, P.J. Scherz, S. Nissim, H. Tian, A.P. McMahon, and C.J. Tabin Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities Cell 118 2004 517 528 (Pubitemid 39485670)
    • (2004) Cell , vol.118 , Issue.4 , pp. 517-528
    • Harfe, B.D.1    Scherz, P.J.2    Nissim, S.3    Tian, H.4    McMahon, A.P.5    Tabin, C.J.6
  • 23
    • 66249105640 scopus 로고    scopus 로고
    • Visualisation and quantification of morphogen gradient formation in the zebrafish
    • S.A. Harvey, and J.C. Smith Visualisation and quantification of morphogen gradient formation in the zebrafish PLoS Biol. 7 2009 e1000101
    • (2009) PLoS Biol. , vol.7 , pp. 1000101
    • Harvey, S.A.1    Smith, J.C.2
  • 24
    • 0027478216 scopus 로고
    • A mouse model of Greig cephalopolysyndactyly syndrome: The extra-toes(J) mutation contains an intragenic deletion of the Gli3 gene
    • DOI 10.1038/ng0393-241
    • C.C. Hui, and A.L. Joyner A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene Nat. Genet. 3 1993 241 246 (Pubitemid 23096560)
    • (1993) Nature Genetics , vol.3 , Issue.3 , pp. 241-246
    • Hui, C.1    Joyner, A.L.2
  • 25
    • 41149127885 scopus 로고    scopus 로고
    • Theoretical and experimental approaches to understand morphogen gradients
    • M. Ibañes, and J.C. Izpisúa Belmonte Theoretical and experimental approaches to understand morphogen gradients Mol. Syst. Biol. 4 2008 176
    • (2008) Mol. Syst. Biol. , vol.4 , pp. 176
    • Ibañes, M.1    Izpisúa Belmonte, J.C.2
  • 26
    • 33750815988 scopus 로고    scopus 로고
    • On the dynamic nature of positional information
    • DOI 10.1002/bies.20494
    • J. Jaeger, and J. Reinitz On the dynamic nature of positional information Bioessays 28 2006 1102 1111 (Pubitemid 44714120)
    • (2006) BioEssays , vol.28 , Issue.11 , pp. 1102-1111
    • Jaeger, J.1    Reinitz, J.2
  • 27
    • 13344275921 scopus 로고    scopus 로고
    • Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1
    • DOI 10.1242/dev.01566
    • J. Jeong, and A.P. McMahon Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1 Development 132 2005 143 154 (Pubitemid 40207974)
    • (2005) Development , vol.132 , Issue.1 , pp. 143-154
    • Jeong, J.1    McMahon, A.P.2
  • 28
    • 0034303585 scopus 로고    scopus 로고
    • Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
    • T.M. Jessell Neuronal specification in the spinal cord: inductive signals and transcriptional codes Nat. Rev. Genet. 1 2000 20 29
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 20-29
    • Jessell, T.M.1
  • 29
    • 0026045994 scopus 로고
    • The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos
    • J. Jiang, D. Kosman, Y.T. Ip, and M. Levine The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos Genes Dev. 5 1991 1881 1891 (Pubitemid 21905882)
    • (1991) Genes and Development , vol.5 , Issue.10 , pp. 1881-1891
    • Jiang, J.1    Kosman, D.2    Ip, Y.T.3    Levine, M.4
  • 30
    • 34447526051 scopus 로고    scopus 로고
    • Specifying Positional Information in the Embryo: Looking Beyond Morphogens
    • DOI 10.1016/j.cell.2007.06.038, PII S0092867407008434
    • M. Kerszberg, and L. Wolpert Specifying positional information in the embryo: looking beyond morphogens Cell 130 2007 205 209 (Pubitemid 47081140)
    • (2007) Cell , vol.130 , Issue.2 , pp. 205-209
    • Kerszberg, M.1    Wolpert, L.2
  • 31
    • 33846300352 scopus 로고    scopus 로고
    • Morpheus Unbound: Reimagining the Morphogen Gradient
    • DOI 10.1016/j.cell.2007.01.004, PII S0092867407000517
    • A.D. Lander Morpheus unbound: reimagining the morphogen gradient Cell 128 2007 245 256 (Pubitemid 46123517)
    • (2007) Cell , vol.128 , Issue.2 , pp. 245-256
    • Lander, A.D.1
  • 33
    • 76049111380 scopus 로고    scopus 로고
    • Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila
    • L.M. Liberman, G.T. Reeves, and A. Stathopoulos Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila Proc. Natl. Acad. Sci. USA 106 2009 22317 22322
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 22317-22322
    • Liberman, L.M.1    Reeves, G.T.2    Stathopoulos, A.3
  • 36
    • 0029975823 scopus 로고    scopus 로고
    • Conservation in hedgehog signaling: Induction of a chicken patched homolog by Sonic hedgehog in the developing limb
    • V. Marigo, M.P. Scott, R.L. Johnson, L.V. Goodrich, and C.J. Tabin Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb Development 122 1996 1225 1233 (Pubitemid 26123897)
    • (1996) Development , vol.122 , Issue.4 , pp. 1225-1233
    • Marigo, V.1    Scott, M.P.2    Johnson, R.L.3    Goodrich, L.V.4    Tabin, C.J.5
  • 37
    • 0031679850 scopus 로고    scopus 로고
    • Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
    • M.P. Matise, D.J. Epstein, H.L. Park, K.A. Platt, and A.L. Joyner Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system Development 125 1998 2759 2770 (Pubitemid 28410201)
    • (1998) Development , vol.125 , Issue.15 , pp. 2759-2770
    • Matise, M.P.1    Epstein, D.J.2    Park, H.L.3    Platt, K.A.4    Joyner, A.L.5
  • 38
    • 70349771959 scopus 로고    scopus 로고
    • Dynamic interpretation of hedgehog signaling in the Drosophila wing disc
    • M. Nahmad, and A. Stathopoulos Dynamic interpretation of hedgehog signaling in the Drosophila wing disc PLoS Biol. 7 2009 e1000202
    • (2009) PLoS Biol. , vol.7 , pp. 1000202
    • Nahmad, M.1    Stathopoulos, A.2
  • 39
    • 0035855795 scopus 로고    scopus 로고
    • Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2
    • DOI 10.1016/S0896-6273(01)00407-X
    • B.G. Novitch, A.I. Chen, and T.M. Jessell Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2 Neuron 31 2001 773 789 (Pubitemid 32907373)
    • (2001) Neuron , vol.31 , Issue.5 , pp. 773-789
    • Novitch, B.G.1    Chen, A.I.2    Jessell, T.M.3
  • 41
    • 62649174030 scopus 로고    scopus 로고
    • Anterior-posterior positional information in the absence of a strong Bicoid gradient
    • A. Ochoa-Espinosa, D. Yu, A. Tsirigos, P. Struffi, and S. Small Anterior-posterior positional information in the absence of a strong Bicoid gradient Proc. Natl. Acad. Sci. USA 106 2009 3823 3828
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3823-3828
    • Ochoa-Espinosa, A.1    Yu, D.2    Tsirigos, A.3    Struffi, P.4    Small, S.5
  • 42
    • 0033955777 scopus 로고    scopus 로고
    • Morphogen gradients. A question of time or concentration?
    • DOI 10.1016/S0168-9525(99)01880-6, PII S0168952599018806
    • F. Pags, and S. Kerridge Morphogen gradients. A question of time or concentration? Trends Genet. 16 2000 40 44 (Pubitemid 30062237)
    • (2000) Trends in Genetics , vol.16 , Issue.1 , pp. 40-44
    • Pages, F.1    Kerridge, S.2
  • 43
    • 34249863319 scopus 로고    scopus 로고
    • A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus
    • Y. Saka, and J.C. Smith A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus BMC Dev. Biol. 7 2007 47
    • (2007) BMC Dev. Biol. , vol.7 , pp. 47
    • Saka, Y.1    Smith, J.C.2
  • 44
    • 0030891148 scopus 로고    scopus 로고
    • A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro
    • H. Sasaki, C. Hui, M. Nakafuku, and H. Kondoh A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro Development 124 1997 1313 1322 (Pubitemid 27190104)
    • (1997) Development , vol.124 , Issue.7 , pp. 1313-1322
    • Sasaki, H.1    Hui, C.-C.2    Nakafuku, M.3    Kondoh, H.4
  • 45
    • 14644401158 scopus 로고    scopus 로고
    • A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube
    • DOI 10.1101/gad.325905
    • D. Stamataki, F. Ulloa, S.V. Tsoni, A. Mynett, and J. Briscoe A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube Genes Dev. 19 2005 626 641 (Pubitemid 40314994)
    • (2005) Genes and Development , vol.19 , Issue.5 , pp. 626-641
    • Stamataki, D.1    Ulloa, F.2    Tsoni, S.V.3    Mynett, A.4    Briscoe, J.5
  • 46
    • 26444591973 scopus 로고    scopus 로고
    • Genomic regulatory networks and animal development
    • DOI 10.1016/j.devcel.2005.09.005, PII S1534580705003400
    • A. Stathopoulos, and M. Levine Genomic regulatory networks and animal development Dev. Cell 9 2005 449 462 (Pubitemid 41430729)
    • (2005) Developmental Cell , vol.9 , Issue.4 , pp. 449-462
    • Stathopoulos, A.1    Levine, M.2
  • 47
    • 0002275384 scopus 로고
    • The dynamics of feedback control circuits in biochemical pathways
    • R. Rosen, F.M. Snell, Academic Press New York
    • J.J. Tyson, and H.G. Othmer The dynamics of feedback control circuits in biochemical pathways R. Rosen, F.M. Snell, Progress in Theoretical Biology Volume 5 1978 Academic Press New York 2 49
    • (1978) Progress in Theoretical Biology , vol.5 , pp. 2-49
    • Tyson, J.J.1    Othmer, H.G.2
  • 49
    • 53549125545 scopus 로고    scopus 로고
    • A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
    • S.A. Vokes, H. Ji, W.H. Wong, and A.P. McMahon A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb Genes Dev. 22 2008 2651 2663
    • (2008) Genes Dev. , vol.22 , pp. 2651-2663
    • Vokes, S.A.1    Ji, H.2    Wong, W.H.3    McMahon, A.P.4
  • 50
    • 51149203927 scopus 로고
    • Canalization of development and the inheritance of acquired characters
    • C.H. Waddington Canalization of development and the inheritance of acquired characters Nature 150 1942 563 565
    • (1942) Nature , vol.150 , pp. 563-565
    • Waddington, C.H.1
  • 53
    • 17744393657 scopus 로고    scopus 로고
    • Peak levels of BMP in the Drosophila embryo control target genes by a feed-forward mechanism
    • DOI 10.1242/dev.01722
    • M. Xu, N. Kirov, and C. Rushlow Peak levels of BMP in the Drosophila embryo control target genes by a feed-forward mechanism Development 132 2005 1637 1647 (Pubitemid 40575864)
    • (2005) Development , vol.132 , Issue.7 , pp. 1637-1647
    • Xu, M.1    Kirov, N.2    Rushlow, C.3
  • 54
    • 0027256437 scopus 로고
    • Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate
    • DOI 10.1016/0092-8674(93)90248-O
    • T. Yamada, S.L. Pfaff, T. Edlund, and T.M. Jessell Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate Cell 73 1993 673 686 (Pubitemid 23159007)
    • (1993) Cell , vol.73 , Issue.4 , pp. 673-686
    • Yamada, T.1    Pfaff, S.L.2    Edlund, T.3    Jessell, T.M.4
  • 55
    • 0037023492 scopus 로고    scopus 로고
    • The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification
    • DOI 10.1016/S0092-8674(02)00677-3
    • Q. Zhou, and D.J. Anderson The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification Cell 109 2002 61 73 (Pubitemid 34327517)
    • (2002) Cell , vol.109 , Issue.1 , pp. 61-73
    • Zhou, Q.1    Anderson, D.J.2
  • 56
    • 0031595311 scopus 로고    scopus 로고
    • The Xt(J) allele generates a Gli3 fusion transcript
    • DOI 10.1007/s003359900845
    • Buscher, D.; Grotewold, L.; Ruther, U. (1998). The XtJ allele generates a Gli3 fusion transcript. Mamm. Genome 9, 676-678. (Pubitemid 28355335)
    • (1998) Mammalian Genome , vol.9 , Issue.8 , pp. 676-678
    • Buscher, D.1    Grotewold, L.2    Ruther, U.3
  • 57
    • 0027254748 scopus 로고
    • A 5' element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in drosophila
    • Chung, J.H.; Whiteley, M.; Felsenfeld, G. (1993). A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74, 505-514. (Pubitemid 23244616)
    • (1993) Cell , vol.74 , Issue.3 , pp. 505-514
    • Chung, J.H.1    Whiteley, M.2    Felsenfeld, G.3
  • 60
    • 36749092279 scopus 로고    scopus 로고
    • Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
    • DOI 10.1038/nature06347, PII NATURE06347
    • Dessaud, E.; Yang, L.L.; Hill, K.; Cox, B.; Ulloa, F.; Ribeiro, A.; Mynett, A.; Novitch, B.G.; Briscoe, J. (2007). Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature 450, 717-720. (Pubitemid 350207693)
    • (2007) Nature , vol.450 , Issue.7170 , pp. 717-720
    • Dessaud, E.1    Yang, L.L.2    Hill, K.3    Cox, B.4    Ulloa, F.5    Ribeiro, A.6    Mynett, A.7    Novitch, B.G.8    Briscoe, J.9
  • 61
    • 0031855859 scopus 로고    scopus 로고
    • Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
    • Ding, Q.; Motoyama, J.; Gasca, S.; Mo, R.; Sasaki, H.; Rossant, J.; Hui, C.C. (1998). Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 125, 2533-2543. (Pubitemid 28396152)
    • (1998) Development , vol.125 , Issue.14 , pp. 2533-2543
    • Ding, Q.1    Motoyama, J.2    Gasca, S.3    Mo, R.4    Sasaki, H.5    Rossant, J.6    Hui, C.-C.7
  • 62
    • 0033993990 scopus 로고    scopus 로고
    • The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types
    • DOI 10.1038/71114
    • Hynes, M.; Ye, W.; Wang, K.; Stone, D.; Murone, M.; Sauvage, F.; Rosenthal, A. (2000). The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types. Nat. Neurosci. 3, 41-46. (Pubitemid 30126346)
    • (2000) Nature Neuroscience , vol.3 , Issue.1 , pp. 41-46
    • Hynes, M.1    Ye, W.2    Wang, K.3    Stone, D.4    Murone, M.5    De Sauvage, F.6    Rosenthal, A.7
  • 63
    • 76249112276 scopus 로고    scopus 로고
    • Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction
    • Ko, H.W.; Norman, R.X.; Tran, J.; Fuller, K.P.; Fukuda, M.; Eggenschwiler, J.T. (2010). Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev. Cell 18, 237-247.
    • (2010) Dev. Cell , vol.18 , pp. 237-247
    • Ko, H.W.1    Norman, R.X.2    Tran, J.3    Fuller, K.P.4    Fukuda, M.5    Eggenschwiler, J.T.6
  • 64
    • 0035368725 scopus 로고    scopus 로고
    • Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1
    • DOI 10.1016/S0092-8674(01)00369-5
    • Lewis, P.M.; Dunn, M.P.; McMahon, J.A.; Logan, M.; Martin, J.F.; St-Jacques, B.; McMahon, A.P. (2001). Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105, 599-612. (Pubitemid 32524113)
    • (2001) Cell , vol.105 , Issue.5 , pp. 599-612
    • Lewis, P.M.1    Dunn, M.P.2    McMahon, J.A.3    Logan, M.4    Martin, J.F.5    St-Jacques, B.6    McMahon, A.P.7
  • 65
    • 0037023529 scopus 로고    scopus 로고
    • Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection
    • DOI 10.1016/S0092-8674(02)00678-5
    • Lu, Q.R.; Sun, T.; Zhu, Z.; Ma, N.; Garcia, M.; Stiles, C.D.; Rowitch, D.H. (2002). Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 109, 75-86. (Pubitemid 34327518)
    • (2002) Cell , vol.109 , Issue.1 , pp. 75-86
    • Lu Q.Richard1    Sun, T.2    Zhu, Z.3    Ma, N.4    Garcia, M.5    Stiles, C.D.6    Rowitch, D.H.7
  • 66
    • 70350521727 scopus 로고    scopus 로고
    • Expression of Patched-1 and Smoothened in testicular meiotic and post-meiotic cells
    • Morales, C.R.; Fox, A.; El-Alfy, M.; Ni, X.; Argraves, W.S. (2009). Expression of Patched-1 and Smoothened in testicular meiotic and post-meiotic cells. Microsc. Res. Tech. 72, 809-815.
    • (2009) Microsc. Res. Tech. , vol.72 , pp. 809-815
    • Morales, C.R.1    Fox, A.2    El-Alfy, M.3    Ni, X.4    Argraves, W.S.5
  • 67
    • 0025884056 scopus 로고
    • Efficient selection for highexpression transfectants with a novel eukaryotic vector
    • Niwa, H.; Yamamura, K.; Miyazaki, J. (1991). Efficient selection for highexpression transfectants with a novel eukaryotic vector. Gene 108, 193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 68
    • 0035855795 scopus 로고    scopus 로고
    • Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2
    • DOI 10.1016/S0896-6273(01)00407-X
    • Novitch, B.G.; Chen, A.I.; Jessell, T.M. (2001). Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Neuron 31, 773-789. (Pubitemid 32907373)
    • (2001) Neuron , vol.31 , Issue.5 , pp. 773-789
    • Novitch, B.G.1    Chen, A.I.2    Jessell, T.M.3
  • 69
    • 0030891148 scopus 로고    scopus 로고
    • A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro
    • Sasaki, H.; Hui, C.; Nakafuku, M.; Kondoh, H. (1997). A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 124, 1313-1322. (Pubitemid 27190104)
    • (1997) Development , vol.124 , Issue.7 , pp. 1313-1322
    • Sasaki, H.1    Hui, C.-C.2    Nakafuku, M.3    Kondoh, H.4
  • 70
    • 0030581164 scopus 로고    scopus 로고
    • Influence of PAX6 gene dosage on development: Overexpression causes severe eye abnormalities
    • DOI 10.1016/S0092-8674(00)80078-1
    • Schedl, A.; Ross, A.; Lee, M.; Engelkamp, D.; Rashbass, P.; van Heyningen, V.; Hastie, N.D. (1996). Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86, 71-82. (Pubitemid 26256579)
    • (1996) Cell , vol.86 , Issue.1 , pp. 71-82
    • Schedl, A.1    Ross, A.2    Lee, M.3    Engelkamp, D.4    Rashbass, P.5    Van Heyningen, V.6    Hastie, N.D.7
  • 71
    • 14644401158 scopus 로고    scopus 로고
    • A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube
    • DOI 10.1101/gad.325905
    • Stamataki, D.; Ulloa, F.; Tsoni, S.V.; Mynett, A.; Briscoe, J. (2005). A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev. 19, 626-641. (Pubitemid 40314994)
    • (2005) Genes and Development , vol.19 , Issue.5 , pp. 626-641
    • Stamataki, D.1    Ulloa, F.2    Tsoni, S.V.3    Mynett, A.4    Briscoe, J.5
  • 72
    • 0027256437 scopus 로고
    • Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate
    • DOI 10.1016/0092-8674(93)90248-O
    • Yamada, T.; Pfaff, S.L.; Edlund, T.; Jessell, T.M. (1993). Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 73, 673-686. (Pubitemid 23159007)
    • (1993) Cell , vol.73 , Issue.4 , pp. 673-686
    • Yamada, T.1    Pfaff, S.L.2    Edlund, T.3    Jessell, T.M.4


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