-
2
-
-
0035064074
-
Calcium signaling mechanisms in T lymphocytes
-
Lewis RS (2001) Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol 19: 497-521.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 497-521
-
-
Lewis, R.S.1
-
3
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris SL, Levine AJ (2005) The p53 pathway: positive and negative feedback loops. Oncogene 24: 2899-2908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
4
-
-
18744361871
-
Enhancement of cellular memory by reducing stochastic transitions
-
Acar M, Becskei A, van Oudenaarden A (2005) Enhancement of cellular memory by reducing stochastic transitions. Nature 435: 228-232.
-
(2005)
Nature
, vol.435
, pp. 228-232
-
-
Acar, M.1
Becskei, A.2
van Oudenaarden, A.3
-
5
-
-
0027509501
-
Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G (1993) Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO Journal 12: 53-63.
-
(1993)
EMBO Journal
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
7
-
-
0027451906
-
Modeling the cell division cycle: M-phase trigger, oscillations, and size control
-
Novak B, Tyson JJ (1993) Modeling the cell division cycle: M-phase trigger, oscillations, and size control. J Theor Biol 165: 101-134.
-
(1993)
J Theor Biol
, vol.165
, pp. 101-134
-
-
Novak, B.1
Tyson, J.J.2
-
8
-
-
0025572247
-
Cyclin activation of p34cdc2
-
Solomon MJ, Glotzer M, Lee TH, Philippe M, Kirschner MW (1990) Cyclin activation of p34cdc2. Cell 63: 1013-1024.
-
(1990)
Cell
, vol.63
, pp. 1013-1024
-
-
Solomon, M.J.1
Glotzer, M.2
Lee, T.H.3
Philippe, M.4
Kirschner, M.W.5
-
10
-
-
0037007225
-
A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization
-
Butty AC, Perrinjaquet N, Petit A, Jaquenoud M, Segall JE, et al. (2002) A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization. The EMBO Journal 21: 1565-1576.
-
(2002)
The EMBO Journal
, vol.21
, pp. 1565-1576
-
-
Butty, A.C.1
Perrinjaquet, N.2
Petit, A.3
Jaquenoud, M.4
Segall, J.E.5
-
11
-
-
0030045345
-
Origins of cell polarity
-
Drubin DG, Nelson WJ (1996) Origins of cell polarity. Cell 84: 335-344.
-
(1996)
Cell
, vol.84
, pp. 335-344
-
-
Drubin, D.G.1
Nelson, W.J.2
-
12
-
-
0037458909
-
Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase
-
Wedlich-Soldner R, Altschuler S, Wu L, Li R (2003) Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science 299: 1231-1235.
-
(2003)
Science
, vol.299
, pp. 1231-1235
-
-
Wedlich-Soldner, R.1
Altschuler, S.2
Wu, L.3
Li, R.4
-
13
-
-
4544295912
-
Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling
-
Wedlich-Soldner R, Wai SC, Schmidt T, Li R (2004) Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J Cell Biol 166: 889-900.
-
(2004)
J Cell Biol
, vol.166
, pp. 889-900
-
-
Wedlich-Soldner, R.1
Wai, S.C.2
Schmidt, T.3
Li, R.4
-
14
-
-
52149120381
-
Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients
-
Chou CS, Nie Q, Yi T (2008) Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients. PLoS ONE 3: e3103.
-
(2008)
PLoS ONE
, vol.3
-
-
Chou, C.S.1
Nie, Q.2
Yi, T.3
-
15
-
-
57349179035
-
Robust spatial sensing of mating pheromone gradients by yeast cells
-
Moore T, Chou CS, Nie Q, Jeon N, Yi TM (2008) Robust spatial sensing of mating pheromone gradients by yeast cells. PLoS ONE 3: e3865.
-
(2008)
PLoS ONE
, vol.3
-
-
Moore, T.1
Chou, C.S.2
Nie, Q.3
Jeon, N.4
Yi, T.M.5
-
16
-
-
1242274449
-
Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
-
Angeli D, Ferrell JE, Sontag ED (2004) Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc Natl Acad Sci USA 101: 1822-1827.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1822-1827
-
-
Angeli, D.1
Ferrell, J.E.2
Sontag, E.D.3
-
17
-
-
40749085952
-
Feedback regulation of opposing enzymes generates robust, allor- none bistable responses
-
Ferrell JE (2008) Feedback regulation of opposing enzymes generates robust, allor- none bistable responses. Current Biology 18: 244-245.
-
(2008)
Current Biology
, vol.18
, pp. 244-245
-
-
Ferrell, J.E.1
-
18
-
-
0037605637
-
Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
-
Ferrell JE, Xiong W (2001) Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. Chaos 11: 221-236.
-
(2001)
Chaos
, vol.11
, pp. 221-236
-
-
Ferrell, J.E.1
Xiong, W.2
-
19
-
-
0029790351
-
Ultrasensitivity in the mitogen-activated protein kinase cascade
-
Huang CY, Ferrell JE (1996) Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 93: 10078-10083.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10078-10083
-
-
Huang, C.Y.1
Ferrell, J.E.2
-
20
-
-
34047258309
-
Positive-feedback loops as a flexible biological module
-
Ingolia NT, Murray AW (2007) Positive-feedback loops as a flexible biological module. Current biology 17: 668-677.
-
(2007)
Current Biology
, vol.17
, pp. 668-677
-
-
Ingolia, N.T.1
Murray, A.W.2
-
21
-
-
46849090495
-
Robust, tunable biological oscillations from interlinked positive and negative feedback loops
-
Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, et al. (2008) Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science 321: 126-129.
-
(2008)
Science
, vol.321
, pp. 126-129
-
-
Tsai, T.Y.1
Choi, Y.S.2
Ma, W.3
Pomerening, J.R.4
Tang, C.5
-
22
-
-
54249137797
-
Feedback loops shape cellular signals in space and time
-
Brandman O, Meyer T (2008) Feedback loops shape cellular signals in space and time. Science 322: 390-395.
-
(2008)
Science
, vol.322
, pp. 390-395
-
-
Brandman, O.1
Meyer, T.2
-
23
-
-
45549097452
-
Positive feedback in cellular control systems
-
Mitrophanov AY, Groisman EA (2008) Positive feedback in cellular control systems. Bioessays 30: 542-555.
-
(2008)
Bioessays
, vol.30
, pp. 542-555
-
-
Mitrophanov, A.Y.1
Groisman, E.A.2
-
25
-
-
0034676456
-
Feedback control of intercellular signalling in development
-
Freeman M (2000) Feedback control of intercellular signalling in development. Nature 408: 313-319.
-
(2000)
Nature
, vol.408
, pp. 313-319
-
-
Freeman, M.1
-
26
-
-
0037078982
-
Control, exploitation and tolerance of intracellular noise
-
Rao CV, Wolf DM, Arkin AP (2002) Control, exploitation and tolerance of intracellular noise. Nature 420: 231-237.
-
(2002)
Nature
, vol.420
, pp. 231-237
-
-
Rao, C.V.1
Wolf, D.M.2
Arkin, A.P.3
-
27
-
-
0842285841
-
Summing up the noise in gene networks
-
Paulsson J (2004) Summing up the noise in gene networks. Nature 427: 415-418.
-
(2004)
Nature
, vol.427
, pp. 415-418
-
-
Paulsson, J.1
-
28
-
-
38949194331
-
Noise propagation and signaling sensitivity in biological networks: A role for positive feedback
-
Hornung G, Barkai N (2008) Noise propagation and signaling sensitivity in biological networks: a role for positive feedback. PLoS Comput Biol 4: e8.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Hornung, G.1
Barkai, N.2
-
29
-
-
53549123008
-
Nature, nurture, or chance: Stochastic gene expression and its consequences
-
Raj A, van Oudenaarden A (2008) Nature, nurture, or chance: Stochastic gene expression and its consequences. Cell 135.
-
(2008)
Cell
, pp. 135
-
-
Raj, A.1
van Oudenaarden, A.2
-
30
-
-
34249079154
-
Network motifs: Theory and experimental approaches
-
Alon U (2007) Network motifs: theory and experimental approaches. Nature Reviews Genetics 8: 450-461.
-
(2007)
Nature Reviews Genetics
, vol.8
, pp. 450-461
-
-
Alon, U.1
-
31
-
-
0034212551
-
Engineering stability in gene networks by autoregulation
-
Becskei A, Serrano L (2000) Engineering stability in gene networks by autoregulation. Nature 405: 590-593.
-
(2000)
Nature
, vol.405
, pp. 590-593
-
-
Becskei, A.1
Serrano, L.2
-
32
-
-
31844449923
-
Gene network shaping of inherent noise spectra
-
Austin D, Allen M, McCollum J, Dar R, Wilgus J, et al. (2006) Gene network shaping of inherent noise spectra. Nature 439: 608-611.
-
(2006)
Nature
, vol.439
, pp. 608-611
-
-
Austin, D.1
Allen, M.2
McCollum, J.3
Dar, R.4
Wilgus, J.5
-
33
-
-
33745725673
-
The effect of negative feedback on noise propagation in transcriptional gene networks
-
Hooshangi S, Weiss R (2006) The effect of negative feedback on noise propagation in transcriptional gene networks. Chaos 16: 026108.
-
(2006)
Chaos
, vol.16
, pp. 026108
-
-
Hooshangi, S.1
Weiss, R.2
-
34
-
-
27144517984
-
Interlinked fast and slow positive feedback loops drive reliable cell decisions
-
Brandman O, Ferrell JE, Li R, Meyer T (2005) Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science 310: 496-498.
-
(2005)
Science
, vol.310
, pp. 496-498
-
-
Brandman, O.1
Ferrell, J.E.2
Li, R.3
Meyer, T.4
-
35
-
-
34848860189
-
Linking fast and slow positive feedback loops creates an optimal bistable switch in cell signaling
-
Zhang XP, Cheng Z, Liu F, Wang W (2007) Linking fast and slow positive feedback loops creates an optimal bistable switch in cell signaling. Physical Review E 76: 031924.
-
(2007)
Physical Review E
, vol.76
, pp. 031924
-
-
Zhang, X.P.1
Cheng, Z.2
Liu, F.3
Wang, W.4
-
36
-
-
33846694082
-
Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways
-
Kim D, Kwon YK, Cho KH (2007) Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways. Bioessays 29: 85-90.
-
(2007)
Bioessays
, vol.29
, pp. 85-90
-
-
Kim, D.1
Kwon, Y.K.2
Cho, K.H.3
-
37
-
-
52149120381
-
Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients
-
Chou CS, Nie Q, Yi TM (2008) Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients. PLoS ONE 3: e3103.
-
(2008)
PLoS ONE
, vol.3
-
-
Chou, C.S.1
Nie, Q.2
Yi, T.M.3
-
38
-
-
53549120986
-
Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria
-
Mitrophanov A, Jewett M, Hadley T, Groisman E (2008) Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria. PLoS Genetics 4.
-
(2008)
PLoS Genetics
, pp. 4
-
-
Mitrophanov, A.1
Jewett, M.2
Hadley, T.3
Groisman, E.4
-
39
-
-
77649275764
-
Response acceleration in post-translationally regulated genetic circuits
-
doi:10.1016/j.jmb.2009.11.043
-
Mitrophanov A, Groisman E (2009) Response acceleration in post-translationally regulated genetic circuits. Journal of Molecular Biologyolecular biology; doi:10.1016/j.jmb.2009.11.043.
-
(2009)
Journal of Molecular Biologyolecular Biology
-
-
Mitrophanov, A.1
Groisman, E.2
-
40
-
-
0035282334
-
Mammalian MAP kinase signaling cascades
-
Chang L, Karin M (2001) Mammalian MAP kinase signaling cascades. Nature 410: 37-40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
41
-
-
0003244685
-
Perturbation Methods in Applied Mathematics
-
Berlin and New York: Springer-Verlag
-
Kevorkian J, Cole JD (1981) Perturbation Methods in Applied Mathematics, volume 34 of Applied Mathematical Sciences. Berlin and New York: Springer-Verlag.
-
(1981)
Applied Mathematical Sciences
, vol.34
-
-
Kevorkian, J.1
Cole, J.D.2
-
43
-
-
0020335520
-
Digital low-pass differentiation for biological signal processing
-
Shiro U, Itzhak A (1982) Digital low-pass differentiation for biological signal processing. IEEE Trans Biomed Engr BME-29: 686-693.
-
(1982)
IEEE Trans Biomed Engr BME
, vol.29
, pp. 686-693
-
-
Shiro, U.1
Itzhak, A.2
-
44
-
-
39949083197
-
Sensitivity of the quorum sensing system is achieved by low pass filtering
-
Müller J, Kuttler C, Hense BA (2008) Sensitivity of the quorum sensing system is achieved by low pass filtering. Biosystems 92: 76-81.
-
(2008)
Biosystems
, vol.92
, pp. 76-81
-
-
Müller, J.1
Kuttler, C.2
Hense, B.A.3
-
45
-
-
67349133121
-
Effects of inadequate low-pass filter application
-
doi:10.1016/j.jelectrocard.2009.03.002
-
Garca-Niebla J, Serra-Autonell G (2009) Effects of inadequate low-pass filter application. J Electrocardiol;doi:10.1016/j.jelectrocard.2009.03.002.
-
(2009)
J Electrocardiol
-
-
Garca-Niebla, J.1
Serra-Autonell, G.2
-
47
-
-
20344389483
-
Models of stochastic gene expression
-
Paulsson J (2005) Models of stochastic gene expression. Phys Life Rev 2: 157-75.
-
(2005)
Phys Life Rev
, vol.2
, pp. 157-175
-
-
Paulsson, J.1
-
49
-
-
0034923514
-
Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
-
Dohlman HG, Thorner JW (2001) Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annu Rev Biochem 70: 703-54.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 703-754
-
-
Dohlman, H.G.1
Thorner, J.W.2
-
50
-
-
0037007225
-
A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization
-
Butty AC, Perrinjaquet N, Petit A, Jaquenoud M, Segall JE, et al. (2002) A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization. Embo J 21: 1565-1576.
-
(2002)
Embo J
, vol.21
, pp. 1565-1576
-
-
Butty, A.C.1
Perrinjaquet, N.2
Petit, A.3
Jaquenoud, M.4
Segall, J.E.5
-
51
-
-
0033635230
-
Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast
-
Gulli MP, Jaquenoud M, Shimada Y, Niederhauser G, Wiget P, et al. (2000) Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast. Mol Cell 6: 1155-1167.
-
(2000)
Mol Cell
, vol.6
, pp. 1155-1167
-
-
Gulli, M.P.1
Jaquenoud, M.2
Shimada, Y.3
Niederhauser, G.4
Wiget, P.5
-
52
-
-
0028884447
-
Pheromone response in yeast: Association of Bem1p with proteins of the MAP kinase cascade and actin
-
Leeuw T, Fourest-Lieuvin A, Wu C, Chenevert J, Clark K, et al. (1995) Pheromone response in yeast: Association of Bem1p with proteins of the MAP kinase cascade and actin. Science 270: 1210-1213.
-
(1995)
Science
, vol.270
, pp. 1210-1213
-
-
Leeuw, T.1
Fourest-Lieuvin, A.2
Wu, C.3
Chenevert, J.4
Clark, K.5
-
53
-
-
37849004725
-
Operating regimes of signaling cycles: Statics, dynamics, and noise filtering
-
Gomez-Uribe C, Verghese GC, Mirny LA (2007) Operating regimes of signaling cycles: Statics, dynamics, and noise filtering. PLoS Comput Biol 3: e246.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Gomez-Uribe, C.1
Verghese, G.C.2
Mirny, L.A.3
-
54
-
-
0026320866
-
The energy landscapes and motions of proteins
-
Frauenfelder H, Sligar SG, Wolynes PG (1991) The energy landscapes and motions of proteins. Science 254: 1598-1603.
-
(1991)
Science
, vol.254
, pp. 1598-1603
-
-
Frauenfelder, H.1
Sligar, S.G.2
Wolynes, P.G.3
-
56
-
-
34047225832
-
Potential energy landscape and robustness of a gene regulatory network: Toggle switch
-
Kim K, Wang J (2007) Potential energy landscape and robustness of a gene regulatory network: toggle switch. PLoS Comput Biol 3: e60.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Kim, K.1
Wang, J.2
-
57
-
-
0036111831
-
Attenuation of noise in ultrasensitive signaling cascades
-
Thattai M, van Oudenaarden A (2002) Attenuation of noise in ultrasensitive signaling cascades. Biophys J 82: 2943-2950.
-
(2002)
Biophys J
, vol.82
, pp. 2943-2950
-
-
Thattai, M.1
van Oudenaarden, A.2
-
58
-
-
33750147302
-
The interplay between discrete noise and nonlinear chemical kinetics in a signal amplification cascade
-
Lan Y, Papoian GA (2006) The interplay between discrete noise and nonlinear chemical kinetics in a signal amplification cascade. J Chem Phys 125: 154901.
-
(2006)
J Chem Phys
, vol.125
, pp. 154901
-
-
Lan, Y.1
Papoian, G.A.2
-
59
-
-
12244257806
-
Noisy signal amplification in ultrasensitive signal transduction
-
Shibata T, Fujimoto K (2005) Noisy signal amplification in ultrasensitive signal transduction. Proc Natl Acad Sci U S A 102: 331-336.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 331-336
-
-
Shibata, T.1
Fujimoto, K.2
-
60
-
-
33746869356
-
Signal detection, modularity, and the correlation between extrinsic and intrinsic noise in biochemical networks
-
Tanase-Nicola S, Warren PB, ten Wolde PR (2006) Signal detection, modularity, and the correlation between extrinsic and intrinsic noise in biochemical networks. Physical review letters 97.
-
(2006)
Physical Review Letters
, pp. 97
-
-
Tanase-Nicola, S.1
Warren, P.B.2
ten Wolde, P.R.3
-
61
-
-
0036285634
-
Mathematical models of protein kinase signal transduction
-
Heinrich R, Neel BG, Rapoport TA (2002) Mathematical models of protein kinase signal transduction. Mol Cell 9: 957-970.
-
(2002)
Mol Cell
, vol.9
, pp. 957-970
-
-
Heinrich, R.1
Neel, B.G.2
Rapoport, T.A.3
-
62
-
-
6344223567
-
Optimal length and signal amplification in weakly activated signal transduction cascades
-
Chaves M, Dinerstein RJ, Sontag ED (2004) Optimal length and signal amplification in weakly activated signal transduction cascades. J Physical Chemistry 108: 15311-15320.
-
(2004)
J Physical Chemistry
, vol.108
, pp. 15311-15320
-
-
Chaves, M.1
Dinerstein, R.J.2
Sontag, E.D.3
-
63
-
-
33748938564
-
Exact computation of amplification for a class of nonlinear systems arising from cellular signaling pathways
-
Chaves M, Sontag ED (2006) Exact computation of amplification for a class of nonlinear systems arising from cellular signaling pathways. Automatica 42: 1987-1992.
-
(2006)
Automatica
, vol.42
, pp. 1987-1992
-
-
Chaves, M.1
Sontag, E.D.2
|