-
1
-
-
0037429649
-
Neuregulins: Functions, forms, and signaling strategies
-
Falls D. Neuregulins: functions, forms, and signaling strategies. Exp Cell Res. 2003;284(1):14-30.
-
(2003)
Exp Cell Res
, vol.284
, Issue.1
, pp. 14-30
-
-
Falls, D.1
-
2
-
-
0026659262
-
Identification of heregulin, a specific activator of p185erbB2
-
Holmes WE, Sliwkowski MX, Akita RW, et al. Identification of heregulin, a specific activator of p185erbB2. Science. 1992;256(5060):1205-10.
-
(1992)
Science
, vol.256
, Issue.5060
, pp. 1205-1210
-
-
Holmes, W.E.1
Sliwkowski, M.X.2
Akita, R.W.3
-
3
-
-
0026776424
-
Isolation of the NeuHER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
-
Peles E, Bacus SS, Koski RA, et al. Isolation of the NeuHER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells. Cell. 1992;69(1):205-16.
-
(1992)
Cell
, vol.69
, Issue.1
, pp. 205-216
-
-
Peles, E.1
Bacus, S.S.2
Koski, R.A.3
-
4
-
-
0026776717
-
Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
-
Wen D, Peles E, Cupples R, et al. Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell. 1992;69(3):559-72.
-
(1992)
Cell
, vol.69
, Issue.3
, pp. 559-572
-
-
Wen, D.1
Peles, E.2
Cupples, R.3
-
5
-
-
0027257581
-
Purification of multiple forms of glial growth factor
-
Goodearl AD, Davis JB, Mistry K, et al. Purification of multiple forms of glial growth factor. J Biol Chem. 1993;268(24):18095-102.
-
(1993)
J Biol Chem
, vol.268
, Issue.24
, pp. 18095-18102
-
-
Goodearl, A.D.1
Davis, J.B.2
Mistry, K.3
-
6
-
-
0027530106
-
Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
-
Marchionni MA, Goodearl AD, Chen MS, et al. Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system. Nature. 1993;362(6418):312-8.
-
(1993)
Nature
, vol.362
, Issue.6418
, pp. 312-318
-
-
Marchionni, M.A.1
Goodearl, A.D.2
Chen, M.S.3
-
7
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
-
Gassmann M, Casagranda F, Orioli D, et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature. 1995;378(6555):390-4.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
-
8
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature. 1995;378(6555):394-8.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
Bates, B.4
Hung, M.C.5
Hauser, C.6
-
9
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature. 1995;378(6555):386-90.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
10
-
-
84903650231
-
Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases
-
Mei L, Nave K-A. Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases. Neuron. 2014;83(1):27-49.
-
(2014)
Neuron
, vol.83
, Issue.1
, pp. 27-49
-
-
Mei, L.1
Nave, K.-A.2
-
11
-
-
84930616399
-
Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
-
Vasti C, Hertig CM. Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines. World J Cardiol. 2014;6(7):653-62.
-
(2014)
World J Cardiol
, vol.6
, Issue.7
, pp. 653-662
-
-
Vasti, C.1
Hertig, C.M.2
-
12
-
-
84861783210
-
The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation
-
Wadugu B, Kühn B. The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation. Am J Physiol Heart Circ Physiol. 2012;302(11):H2139-47.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
, Issue.11
, pp. H2139-H2147
-
-
Wadugu, B.1
Kühn, B.2
-
13
-
-
0035174126
-
The role of HER2 in angiogenesis
-
Kumar R, Yarmand-Bagheri R. The role of HER2 in angiogenesis. Semin Oncol. 2001;28(5 suppl 16):27-32.
-
(2001)
Semin Oncol
, vol.28
, Issue.5
, pp. 27-32
-
-
Kumar, R.1
Yarmand-Bagheri, R.2
-
14
-
-
77949272136
-
Neuregulin signaling and heart failure
-
Jiang Z, Zhou M. Neuregulin signaling and heart failure. Curr Heart Fail Rep. 2010;7(1):42-7.
-
(2010)
Curr Heart Fail Rep
, vol.7
, Issue.1
, pp. 42-47
-
-
Jiang, Z.1
Zhou, M.2
-
15
-
-
0035368610
-
Neuregulin and ErbB receptor signaling pathways in the nervous system
-
Buonanno A, Fischbach GD. Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr Opin Neurobiol. 2001;11(3):287-96.
-
(2001)
Curr Opin Neurobiol
, vol.11
, Issue.3
, pp. 287-296
-
-
Buonanno, A.1
Fischbach, G.D.2
-
16
-
-
33847636796
-
Meltrin beta (ADAM19) mediates ectodomain shedding of Neuregulin beta1 in the Golgi apparatus: Fluorescence correlation spectroscopic observation of the dynamics of ectodomain shedding in living cells
-
Yokozeki T, Wakatsuki S, Hatsuzawa K, Black RA, Wada I, Sehara-Fujisawa A. Meltrin beta (ADAM19) mediates ectodomain shedding of Neuregulin beta1 in the Golgi apparatus: fluorescence correlation spectroscopic observation of the dynamics of ectodomain shedding in living cells. Genes Cells. 2007;12(3):329-43.
-
(2007)
Genes Cells
, vol.12
, Issue.3
, pp. 329-343
-
-
Yokozeki, T.1
Wakatsuki, S.2
Hatsuzawa, K.3
Black, R.A.4
Wada, I.5
Sehara-Fujisawa, A.6
-
17
-
-
33845236399
-
Bace1 modulates myelination in the central and peripheral nervous system
-
Hu X, Hicks CW, He W, et al. Bace1 modulates myelination in the central and peripheral nervous system. Nat Neurosci. 2006;9(12):1520-5.
-
(2006)
Nat Neurosci
, vol.9
, Issue.12
, pp. 1520-1525
-
-
Hu, X.1
Hicks, C.W.2
He, W.3
-
18
-
-
0034533443
-
Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-alpha-converting enzyme
-
Montero JC, Yuste L, Díaz-Rodríguez E, Esparís-Ogando A, Pandiella A. Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-alpha-converting enzyme. Mol Cell Neurosci. 2000;16(5):631-48.
-
(2000)
Mol Cell Neurosci
, vol.16
, Issue.5
, pp. 631-648
-
-
Montero, J.C.1
Yuste, L.2
Díaz-Rodríguez, E.3
Esparís-Ogando, A.4
Pandiella, A.5
-
19
-
-
84872031728
-
Neuregulin in cardiovascular development and disease
-
Odiete O, Hill MF, Sawyer DB. Neuregulin in cardiovascular development and disease. Circ Res. 2012;111(10):1376-85.
-
(2012)
Circ Res
, vol.111
, Issue.10
, pp. 1376-1385
-
-
Odiete, O.1
Hill, M.F.2
Sawyer, D.B.3
-
20
-
-
84870461501
-
The involvement of type II neuregulin-1 in rat visuospatial learning and memory
-
Taylor AR, Taylor SB, Koenig JI. The involvement of type II neuregulin-1 in rat visuospatial learning and memory. Neurosci Lett. 2012;531(2):131-5.
-
(2012)
Neurosci Lett
, vol.531
, Issue.2
, pp. 131-135
-
-
Taylor, A.R.1
Taylor, S.B.2
Koenig, J.I.3
-
21
-
-
2542451853
-
Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia
-
Corfas G, Roy K, Buxbaum JD. Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia. Nat Neurosci. 2004;7(6):575-80.
-
(2004)
Nat Neurosci
, vol.7
, Issue.6
, pp. 575-580
-
-
Corfas, G.1
Roy, K.2
Buxbaum, J.D.3
-
22
-
-
0035256698
-
Untangling the ErbB signalling network
-
Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol. 2001;2(2):127-37.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, Issue.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
23
-
-
0033009389
-
Binding specificities and affinities of egf domains for ErbB receptors
-
Jones JT, Akita RW, Sliwkowski MX. Binding specificities and affinities of egf domains for ErbB receptors. FEBS Lett. 1999;447(2-3):227-31.
-
(1999)
FEBS Lett
, vol.447
, Issue.2-3
, pp. 227-231
-
-
Jones, J.T.1
Akita, R.W.2
Sliwkowski, M.X.3
-
24
-
-
84879501615
-
A common missense variant in the neuregulin 1 gene is associated with both schizophrenia and sudden cardiac death
-
Huertas-Vazquez A, Teodorescu C, Reinier K, et al. A common missense variant in the neuregulin 1 gene is associated with both schizophrenia and sudden cardiac death. Heart Rhythm. 2013;10(7):994-8.
-
(2013)
Heart Rhythm
, vol.10
, Issue.7
, pp. 994-998
-
-
Huertas-Vazquez, A.1
Teodorescu, C.2
Reinier, K.3
-
25
-
-
79952593835
-
Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects
-
McBride KL, Zender GA, Fitzgerald-Butt SM, et al. Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects. Birth Defects Res A Clin Mol Teratol. 2011;91(3):162-8.
-
(2011)
Birth Defects Res a Clin Mol Teratol
, vol.91
, Issue.3
, pp. 162-168
-
-
McBride, K.L.1
Zender, G.A.2
Fitzgerald-Butt, S.M.3
-
26
-
-
84916630619
-
Neuregulin 1-activated ERBB4 as a “dedicated” receptor for the Hippo-YAP pathway
-
Sudol M. Neuregulin 1-activated ERBB4 as a “dedicated” receptor for the Hippo-YAP pathway. Sci Signal. 2014;7(355):e29.
-
(2014)
Sci Signal
, vol.7
, Issue.355
-
-
Sudol, M.1
-
27
-
-
84924848508
-
Actin binding GFP allows 4D in vivo imaging of myofilament dynamics in the zebrafish heart and the identification of Erbb2 signaling as a remodeling factor of myofibril architecture
-
Reischauer S, Arnaout R, Ramadass R, Stainier DYR. Actin binding GFP allows 4D in vivo imaging of myofilament dynamics in the zebrafish heart and the identification of Erbb2 signaling as a remodeling factor of myofibril architecture. Circ Res. 2014;115(10):845-56.
-
(2014)
Circ Res
, vol.115
, Issue.10
, pp. 845-856
-
-
Reischauer, S.1
Arnaout, R.2
Ramadass, R.3
Stainier, D.4
-
28
-
-
0033601174
-
Synergistic roles of neuregulin-1 and insulin-like growth factor-I in activation of the phosphatidylinositol 3-kinase pathway and cardiac chamber morphogenesis
-
Hertig CM, Kubalak SW, Wang Y, Chien KR. Synergistic roles of neuregulin-1 and insulin-like growth factor-I in activation of the phosphatidylinositol 3-kinase pathway and cardiac chamber morphogenesis. J Biol Chem. 1999;274(52):37362-9.
-
(1999)
J Biol Chem
, vol.274
, Issue.52
, pp. 37362-37369
-
-
Hertig, C.M.1
Kubalak, S.W.2
Wang, Y.3
Chien, K.R.4
-
29
-
-
0032714208
-
NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70S6K, and MEK-MAPK-RSK
-
Baliga RR, Pimental DR, Zhao YY, et al. NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70S6K, and MEK-MAPK-RSK. Am J Physiol Hear Circ Physiol. 1999;277(5):H2026-37.
-
(1999)
Am J Physiol Hear Circ Physiol
, vol.277
, Issue.5
, pp. H2026-H2037
-
-
Baliga, R.R.1
Pimental, D.R.2
Zhao, Y.Y.3
-
30
-
-
0036677402
-
Neuregulin-1 promotes formation of the murine cardiac conduction system
-
Rentschler S, Zander J, Meyers K, et al. Neuregulin-1 promotes formation of the murine cardiac conduction system. Proc Natl Acad Sci U S A. 2002;99(16):10464-9.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.16
, pp. 10464-10469
-
-
Rentschler, S.1
Zander, J.2
Meyers, K.3
-
31
-
-
58549114851
-
Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells
-
Wang Z, Xu G, Wu Y, et al. Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells. Med Biol Eng Comput. 2009;47(1):41-8.
-
(2009)
Med Biol Eng Comput
, vol.47
, Issue.1
, pp. 41-48
-
-
Wang, Z.1
Xu, G.2
Wu, Y.3
-
32
-
-
84879797348
-
Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells
-
Chen M, Bi L-L, Wang Z-Q, Zhao F, Gan X-D, Wang Y-G. Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells. Mol Cell Biochem. 2013;380(1-2):67-72.
-
(2013)
Mol Cell Biochem
, vol.380
, Issue.1-2
, pp. 67-72
-
-
Chen, M.1
Bi, L.-L.2
Wang, Z.-Q.3
Zhao, F.4
Gan, X.-D.5
Wang, Y.-G.6
-
33
-
-
17444423730
-
Endothelin-1 and neuregulin-1 convert embryonic cardiomyocytes into cells of the conduction system in the mouse
-
Patel R, Kos L. Endothelin-1 and neuregulin-1 convert embryonic cardiomyocytes into cells of the conduction system in the mouse. Dev Dyn. 2005;233(1):20-8.
-
(2005)
Dev Dyn
, vol.233
, Issue.1
, pp. 20-28
-
-
Patel, R.1
Kos, L.2
-
34
-
-
79959858737
-
Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: Differential expression of microRNA
-
Sun M, Yan X, Bian Y, Caggiano AO, Morgan JP. Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: differential expression of microRNA. Am J Physiol Cell Physiol. 2011;301(1):C21-30.
-
(2011)
Am J Physiol Cell Physiol
, vol.301
, Issue.1
, pp. C21-C30
-
-
Sun, M.1
Yan, X.2
Bian, Y.3
Caggiano, A.O.4
Morgan, J.P.5
-
35
-
-
84894286214
-
Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors
-
Hao J, Galindo CL, Tran T-L, Sawyer DB. Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors. Biochem J. 2014;458(2):335-41.
-
(2014)
Biochem J
, vol.458
, Issue.2
, pp. 335-341
-
-
Hao, J.1
Galindo, C.L.2
Tran, T.-L.3
Sawyer, D.B.4
-
36
-
-
0032562770
-
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
-
Zhao YY, Sawyer DR, Baliga RR, et al. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem. 1998;273(17):10261-9.
-
(1998)
J Biol Chem
, vol.273
, Issue.17
, pp. 10261-10269
-
-
Zhao, Y.Y.1
Sawyer, D.R.2
Baliga, R.R.3
-
37
-
-
77957270888
-
Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
-
Zhu W-Z, Xie Y, Moyes KW, Gold JD, Askari B, Laflamme MA. Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells. Circ Res. 2010;107(6):776-86.
-
(2010)
Circ Res
, vol.107
, Issue.6
, pp. 776-786
-
-
Zhu, W.-Z.1
Xie, Y.2
Moyes, K.W.3
Gold, J.D.4
Askari, B.5
Laflamme, M.A.6
-
38
-
-
84859724714
-
Mitochondria death/survival signaling pathways in cardiotoxicity induced by anthracyclines and anticancer-targeted therapies
-
Montaigne D, Hurt C, Neviere R. Mitochondria death/survival signaling pathways in cardiotoxicity induced by anthracyclines and anticancer-targeted therapies. Biochem Res Int. 2012;2012:951539.
-
(2012)
Biochem Res Int
, vol.2012
-
-
Montaigne, D.1
Hurt, C.2
Neviere, R.3
-
39
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev. 2004;56(2):185-229.
-
(2004)
Pharmacol Rev
, vol.56
, Issue.2
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
40
-
-
84907352671
-
Prevention of anthracycline-induced cardiotoxicity
-
Vejpongsa P, Yeh ETH. Prevention of anthracycline-induced cardiotoxicity. J Am Coll Cardiol. 2014;64(9):938-45.
-
(2014)
J am Coll Cardiol
, vol.64
, Issue.9
, pp. 938-945
-
-
Vejpongsa, P.1
Yeh, E.2
-
41
-
-
77955891306
-
Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
-
Horie T, Ono K, Nishi H, et al. Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway. Cardiovasc Res. 2010;87(4):656-64.
-
(2010)
Cardiovasc Res
, vol.87
, Issue.4
, pp. 656-664
-
-
Horie, T.1
Ono, K.2
Nishi, H.3
-
42
-
-
0037007076
-
Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: Potential mechanism for trastuzumab-induced cardiotoxicity
-
Sawyer DB. Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation. 2002;105(13):1551-4.
-
(2002)
Circulation
, vol.105
, Issue.13
, pp. 1551-1554
-
-
Sawyer, D.B.1
-
43
-
-
21644470216
-
Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta
-
Giraud M-N, Flück M, Zuppinger C, Suter TM. Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta. J Appl Physiol. 2005;99(1):313-22.
-
(2005)
J Appl Physiol
, vol.99
, Issue.1
, pp. 313-322
-
-
Giraud, M.-N.1
Flück, M.2
Zuppinger, C.3
Suter, T.M.4
-
44
-
-
84863368665
-
NRG-1 attenuates mitochondrial dysfunction in a rat model of heart failure
-
Guo Yong-fang WX. NRG-1 attenuates mitochondrial dysfunction in a rat model of heart failure. Chin Med J. 2012;125(5):807-14.
-
(2012)
Chin Med J
, vol.125
, Issue.5
, pp. 807-814
-
-
Guo Yong-Fang, W.X.1
-
45
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
Crone SA, Zhao YY, Fan L, et al. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med. 2002;8(5):459-65.
-
(2002)
Nat Med
, vol.8
, Issue.5
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.Y.2
Fan, L.3
-
46
-
-
84875070234
-
ErbB/integrin signaling interactions in regulation of myocardial cell-cell and cell-matrix interactions
-
Pentassuglia L, Sawyer DB. ErbB/integrin signaling interactions in regulation of myocardial cell-cell and cell-matrix interactions. Biochim Biophys Acta. 2013;1833(4):909-16.
-
(2013)
Biochim Biophys Acta
, vol.1833
, Issue.4
, pp. 909-916
-
-
Pentassuglia, L.1
Sawyer, D.B.2
-
47
-
-
33746048823
-
Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes
-
Kuramochi Y, Guo X, Sawyer DB. Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes. J Mol Cell Cardiol. 2006;41(2):228-35.
-
(2006)
J Mol Cell Cardiol
, vol.41
, Issue.2
, pp. 228-235
-
-
Kuramochi, Y.1
Guo, X.2
Sawyer, D.B.3
-
48
-
-
27344447301
-
Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro
-
Cote GM, Miller TA, Lebrasseur NK, Kuramochi Y, Sawyer DB. Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro. Exp Cell Res. 2005;311(1):135-46.
-
(2005)
Exp Cell Res
, vol.311
, Issue.1
, pp. 135-146
-
-
Cote, G.M.1
Miller, T.A.2
Lebrasseur, N.K.3
Kuramochi, Y.4
Sawyer, D.B.5
-
49
-
-
34548394227
-
Neuregulins increase mitochondrial oxidative capacity and insulin sensitivity in skeletal muscle cells
-
Cantó C, Pich S, Paz JC, et al. Neuregulins increase mitochondrial oxidative capacity and insulin sensitivity in skeletal muscle cells. Diabetes. 2007;56(9):2185-93.
-
(2007)
Diabetes
, vol.56
, Issue.9
, pp. 2185-2193
-
-
Cantó, C.1
Pich, S.2
Paz, J.C.3
-
50
-
-
0035824526
-
Neuregulin rescues PC12-ErbB4 cells from cell death induced by H(2)O(2). Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase
-
Goldshmit Y, Erlich S, Pinkas-Kramarski R. Neuregulin rescues PC12-ErbB4 cells from cell death induced by H(2)O(2). Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase. J Biol Chem. 2001;276(49):46379-85.
-
(2001)
J Biol Chem
, vol.276
, Issue.49
, pp. 46379-46385
-
-
Goldshmit, Y.1
Erlich, S.2
Pinkas-Kramarski, R.3
-
51
-
-
84890303109
-
The growth factor receptor ERBB2 regulates mitochondrial activity on a signaling time scale
-
Patel N, Barrientos A, Landgraf R. The growth factor receptor ERBB2 regulates mitochondrial activity on a signaling time scale. J Biol Chem. 2013;288(49):35253-65.
-
(2013)
J Biol Chem
, vol.288
, Issue.49
, pp. 35253-35265
-
-
Patel, N.1
Barrientos, A.2
Landgraf, R.3
-
52
-
-
84922450324
-
The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation
-
Waring CD, Vicinanza C, Papalamprou A, et al. The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation. Eur Heart J. 2012;35(39):2722-31.
-
(2012)
Eur Heart J
, vol.35
, Issue.39
, pp. 2722-2731
-
-
Waring, C.D.1
Vicinanza, C.2
Papalamprou, A.3
-
53
-
-
84900331122
-
A proliferative burst during preadolescence establishes the final cardiomyocyte number
-
Naqvi N, Li M, Calvert JW, et al. A proliferative burst during preadolescence establishes the final cardiomyocyte number. Cell. 2014;157(4):795-807.
-
(2014)
Cell
, vol.157
, Issue.4
, pp. 795-807
-
-
Naqvi, N.1
Li, M.2
Calvert, J.W.3
-
54
-
-
79955052182
-
Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy
-
Lemmens K, Doggen K, De Keulenaer GW. Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am J Physiol Heart Circ Physiol. 2011;300(3):H931-42.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, Issue.3
, pp. H931-H942
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
55
-
-
4043110498
-
Neuregulins regulate cardiac parasympathetic activity: Muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion
-
Okoshi K, Nakayama M, Yan X, et al. Neuregulins regulate cardiac parasympathetic activity: muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion. Circulation. 2004;110(6):713-7.
-
(2004)
Circulation
, vol.110
, Issue.6
, pp. 713-717
-
-
Okoshi, K.1
Nakayama, M.2
Yan, X.3
-
56
-
-
1642458136
-
Neuregulin-1 induces a negative inotropic effect in cardiac muscle: Role of nitric oxide synthase
-
Lemmens K, Fransen P, Sys SU, Brutsaert DL, De Keulenaer GW. Neuregulin-1 induces a negative inotropic effect in cardiac muscle: role of nitric oxide synthase. Circulation. 2004;109(3):324-6.
-
(2004)
Circulation
, vol.109
, Issue.3
, pp. 324-326
-
-
Lemmens, K.1
Fransen, P.2
Sys, S.U.3
Brutsaert, D.L.4
De Keulenaer, G.W.5
-
57
-
-
0742305448
-
Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta
-
Kuramochi Y, Lim CC, Guo X, Colucci WS, Liao R, Sawyer DB. Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta. Am J Physiol Cell Physiol. 2004;286(2):C222-9.
-
(2004)
Am J Physiol Cell Physiol
, vol.286
, Issue.2
, pp. C222-C229
-
-
Kuramochi, Y.1
Lim, C.C.2
Guo, X.3
Colucci, W.S.4
Liao, R.5
Sawyer, D.B.6
-
58
-
-
84897526216
-
Recent insights in the paracrine modulation of cardiomyocyte contractility by cardiac endothelial cells
-
Noireaud J, Andriantsitohaina R. Recent insights in the paracrine modulation of cardiomyocyte contractility by cardiac endothelial cells. Biomed Res Int. 2014;2014:923805.
-
(2014)
Biomed Res Int
, vol.2014
-
-
Noireaud, J.1
Riantsitohaina, R.2
-
59
-
-
78649919273
-
Cytostatic drugs, neuregulin activation of erbB receptors, and angiogenesis
-
Hedhli N, Russell KS. Cytostatic drugs, neuregulin activation of erbB receptors, and angiogenesis. Curr Hypertens Rep. 2010;12(6):411-7.
-
(2010)
Curr Hypertens Rep
, vol.12
, Issue.6
, pp. 411-417
-
-
Hedhli, N.1
Russell, K.S.2
-
60
-
-
10944236872
-
Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling
-
Kuramochi Y, Cote GM, Guo X, et al. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling. J Biol Chem. 2004;279(49):51141-7.
-
(2004)
J Biol Chem
, vol.279
, Issue.49
, pp. 51141-51147
-
-
Kuramochi, Y.1
Cote, G.M.2
Guo, X.3
-
61
-
-
33745805840
-
Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk
-
Lemmens K, Segers VFM, Demolder M, De Keulenaer GW. Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk. J Biol Chem. 2006;281(28):19469-77.
-
(2006)
J Biol Chem
, vol.281
, Issue.28
, pp. 19469-19477
-
-
Lemmens, K.1
Segers, V.2
Demolder, M.3
De Keulenaer, G.W.4
-
62
-
-
77954454429
-
Metalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells
-
Kalinowski A, Plowes NJR, Huang Q, Berdejo-Izquierdo C, Russell RR, Russell KS. Metalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells. FASEB J. 2010;24(7):2567-75.
-
(2010)
FASEB J
, vol.24
, Issue.7
, pp. 2567-2575
-
-
Kalinowski, A.1
Plowes, N.2
Huang, Q.3
Berdejo-Izquierdo, C.4
Russell, R.R.5
Russell, K.S.6
-
63
-
-
34547191653
-
Intra- and extracellular signaling by endothelial neuregulin-1
-
Iivanainen E, Paatero I, Heikkinen SM, et al. Intra- and extracellular signaling by endothelial neuregulin-1. Exp Cell Res. 2007;313(13):2896-909.
-
(2007)
Exp Cell Res
, vol.313
, Issue.13
, pp. 2896-2909
-
-
Iivanainen, E.1
Paatero, I.2
Heikkinen, S.M.3
-
64
-
-
84886739006
-
Relationship between clinical data and gene expression in the HER2/ErbB2-dependent signaling pathway in patients with acute heart failure
-
Szmit S, Jank M, Maciejewski H, et al. Relationship between clinical data and gene expression in the HER2/ErbB2-dependent signaling pathway in patients with acute heart failure. J Appl Genet. 2013;54(4):447-53.
-
(2013)
J Appl Genet
, vol.54
, Issue.4
, pp. 447-453
-
-
Szmit, S.1
Jank, M.2
Maciejewski, H.3
-
65
-
-
78650612002
-
Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism
-
Fang SJ, Wu XS, Han ZH, et al. Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism. Chin Med J (Engl). 2010;123(24):3597-604.
-
(2010)
Chin Med J (Engl)
, vol.123
, Issue.24
, pp. 3597-3604
-
-
Fang, S.J.1
Wu, X.S.2
Han, Z.H.3
-
66
-
-
79958172866
-
Endothelium-derived neuregulin protects the heart against ischemic injury
-
Hedhli N, Huang Q, Kalinowski A, et al. Endothelium-derived neuregulin protects the heart against ischemic injury. Circulation. 2011;123(20):2254-62.
-
(2011)
Circulation
, vol.123
, Issue.20
, pp. 2254-2262
-
-
Hedhli, N.1
Huang, Q.2
Kalinowski, A.3
-
67
-
-
84867579183
-
Therapeutic effects of neuregulin-1 gene transduction in rats with myocardial infarction
-
Xiao J, Li B, Zheng Z, et al. Therapeutic effects of neuregulin-1 gene transduction in rats with myocardial infarction. Coron Artery Dis. 2012;23(7):460-8.
-
(2012)
Coron Artery Dis
, vol.23
, Issue.7
, pp. 460-468
-
-
Xiao, J.1
Li, B.2
Zheng, Z.3
-
68
-
-
84888106647
-
Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration
-
Formiga FR, Pelacho B, Garbayo E, et al. Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration. J Control Release. 2014;173:132-9.
-
(2014)
J Control Release
, vol.173
, pp. 132-139
-
-
Formiga, F.R.1
Pelacho, B.2
Garbayo, E.3
-
69
-
-
67650569135
-
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
-
Bersell K, Arab S, Haring B, Kühn B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell. 2009;138(2):257-70.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 257-270
-
-
Bersell, K.1
Arab, S.2
Haring, B.3
Kühn, B.4
-
70
-
-
77958086724
-
Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin
-
Gu X, Liu X, Xu D, et al. Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin. Cardiovasc Res. 2010;88(2):334-43.
-
(2010)
Cardiovasc Res
, vol.88
, Issue.2
, pp. 334-343
-
-
Gu, X.1
Liu, X.2
Xu, D.3
-
71
-
-
84930674628
-
Anti-remodeling and anti-fibrotic effects of the neuregulin-1β glial growth factor 2 in a large animal model of heart failure
-
Galindo CL, Kasasbeh E, Murphy A, et al. Anti-remodeling and anti-fibrotic effects of the neuregulin-1β glial growth factor 2 in a large animal model of heart failure. J Am Heart Assoc. 2014;3(5):e000773.
-
(2014)
J am Heart Assoc
, vol.3
, Issue.5
-
-
Galindo, C.L.1
Kasasbeh, E.2
Murphy, A.3
-
72
-
-
84874289558
-
Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction
-
Hill MF, Patel AV, Murphy A, et al. Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction. PLoS One. 2013;8(2):e55741.
-
(2013)
Plos One
, vol.8
, Issue.2
-
-
Hill, M.F.1
Patel, A.V.2
Murphy, A.3
-
73
-
-
33748929841
-
Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy
-
Liu X, Gu X, Li Z, et al. Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol. 2006;48(7):1438-47.
-
(2006)
J am Coll Cardiol
, vol.48
, Issue.7
, pp. 1438-1447
-
-
Liu, X.1
Gu, X.2
Li, Z.3
-
74
-
-
68249087127
-
Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure
-
Ky B, Kimmel SE, Safa RN, et al. Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure. Circulation. 2009;120(4):310-7.
-
(2009)
Circulation
, vol.120
, Issue.4
, pp. 310-317
-
-
Ky, B.1
Kimmel, S.E.2
Safa, R.N.3
-
75
-
-
25144465666
-
Neuregulin receptors erbB2 and erbB4 in failing human myocardium - depressed expression and attenuated activation
-
Rohrbach S, Niemann B, Silber R-E, Holtz J. Neuregulin receptors erbB2 and erbB4 in failing human myocardium - depressed expression and attenuated activation. Basic Res Cardiol. 2005;100(3):240-9.
-
(2005)
Basic Res Cardiol
, vol.100
, Issue.3
, pp. 240-249
-
-
Rohrbach, S.1
Niemann, B.2
Silber, R.-E.3
Holtz, J.4
-
76
-
-
0036289525
-
Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart
-
Uray IP, Connelly JH, Thomázy V, et al. Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart. J Hear Lung Transplant. 2002;21(7):771-82.
-
(2002)
J Hear Lung Transplant
, vol.21
, Issue.7
, pp. 771-782
-
-
Uray, I.P.1
Connelly, J.H.2
Thomázy, V.3
-
77
-
-
0033609458
-
Neuregulin in cardiac hypertrophy in rats with aortic stenosis: Differential expression of erbB2 and erbB4 Receptors
-
Rohrbach S, Yan X, Weinberg EO, et al. Neuregulin in cardiac hypertrophy in rats with aortic stenosis: differential expression of erbB2 and erbB4 Receptors. Circulation. 1999;100(4):407-12.
-
(1999)
Circulation
, vol.100
, Issue.4
, pp. 407-412
-
-
Rohrbach, S.1
Yan, X.2
Weinberg, E.O.3
-
78
-
-
79960888603
-
Therapeutic effects of neuregulin-1 in diabetic cardiomyopathy rats
-
Li B, Zheng Z, Wei Y, et al. Therapeutic effects of neuregulin-1 in diabetic cardiomyopathy rats. Cardiovasc Diabetol. 2011;10:69.
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 69
-
-
Li, B.1
Zheng, Z.2
Wei, Y.3
-
79
-
-
84930651656
-
Study of efficacy on cardiac remodeling of recombinant human neuregulin-1 in stable chronic systolic heart failure patients
-
Accessed February 26, 2015
-
Gao R. Study of efficacy on cardiac remodeling of recombinant human neuregulin-1 in stable chronic systolic heart failure patients. 2012. Home - ClinicalTrials.gov. 2015. Available at: https://clinicaltrials.gov/. Accessed February 26, 2015.
-
(2012)
Home - Clinicaltrials.Gov
, vol.2015
-
-
Gao, R.1
-
80
-
-
84930646964
-
Study of efficacy on NT-proBNP of recombinant human neuregulin-1 in chronic heart failure patients
-
Accessed February 26, 2015
-
Gao R. Study of efficacy on NT-proBNP of recombinant human neuregulin-1 in chronic heart failure patients. Home - ClinicalTrials.gov. 2015. Available at: https://clinicaltrials.gov/. Accessed February 26, 2015.
-
(2015)
Home - Clinicaltrials.Gov
-
-
Gao, R.1
-
81
-
-
84930637145
-
Clinical trial to evaluate the efficacy and safety of recombinant human neuregulin-1
-
Accessed February 26, 2015
-
Gao R. Clinical trial to evaluate the efficacy and safety of recombinant human neuregulin-1. Home - ClinicalTrials.gov. 2015. Available at: https://clinicaltrials.gov/. Accessed February 26, 2015.
-
(2015)
Home - Clinicaltrials.Gov
-
-
Gao, R.1
-
82
-
-
84883242344
-
Therapeutic potential of neuregulin-1 in cardiovascular disease
-
Mendes-Ferreira P, De Keulenaer GW, Leite-Moreira AF, Brás-Silva C. Therapeutic potential of neuregulin-1 in cardiovascular disease. Drug Discov Today. 2013;18(17-8):836-42.
-
(2013)
Drug Discov Today
, vol.18
, Issue.17-8
, pp. 836-842
-
-
Mendes-Ferreira, P.1
De Keulenaer, G.W.2
Leite-Moreira, A.F.3
Brás-Silva, C.4
-
83
-
-
77952317892
-
A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
-
Gao R, Zhang J, Cheng L, et al. A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol. 2010;55(18):1907-14.
-
(2010)
J am Coll Cardiol
, vol.55
, Issue.18
, pp. 1907-1914
-
-
Gao, R.1
Zhang, J.2
Cheng, L.3
-
84
-
-
78650412123
-
Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses
-
Jabbour A, Hayward CS, Keogh AM, et al. Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses. Eur J Heart Fail. 2011;13(1):83-92.
-
(2011)
Eur J Heart Fail
, vol.13
, Issue.1
, pp. 83-92
-
-
Jabbour, A.1
Hayward, C.S.2
Keogh, A.M.3
-
85
-
-
84863560929
-
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
-
Lian X, Hsiao C, Wilson G, et al. Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A. 2012;109(27):E1848-57.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.27
, pp. E1848-E1857
-
-
Lian, X.1
Hsiao, C.2
Wilson, G.3
-
86
-
-
84905242471
-
Chemically defined generation of human cardiomyocytes
-
Burridge PW, Matsa E, Shukla P, et al. Chemically defined generation of human cardiomyocytes. Nat Methods. 2014;11(8):855-60.
-
(2014)
Nat Methods
, vol.11
, Issue.8
, pp. 855-860
-
-
Burridge, P.W.1
Matsa, E.2
Shukla, P.3
-
87
-
-
79956334658
-
Heart regeneration
-
Laflamme MA, Murry CE. Heart regeneration. Nature. 2011;473(7347):326-35.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 326-335
-
-
Laflamme, M.A.1
Murry, C.E.2
-
88
-
-
84930635059
-
-
Accessed February 26, 2015
-
Home - ClinicalTrials.gov. 2015. Available at: https://clinicaltrials.gov/. Accessed February 26, 2015.
-
(2015)
Home - Clinicaltrials.Gov
-
-
|