메뉴 건너뛰기




Volumn 125, Issue 5, 2012, Pages 807-814

Neuregulin-1 attenuates mitochondrial dysfunction in a rat model of heart failure

Author keywords

Cardioprotection; Heart failure; Mitochondria; Neuregulin 1

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C; GLUTATHIONE PEROXIDASE; NEU DIFFERENTIATION FACTOR; REACTIVE OXYGEN METABOLITE; RECOMBINANT PROTEIN;

EID: 84863368665     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.05.015     Document Type: Article
Times cited : (31)

References (37)
  • 1
    • 33748929841 scopus 로고    scopus 로고
    • Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy
    • Liu X, Gu X, Li Z, Li X, Li H, Chang J, et al. Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol 2006; 48: 1438-1447.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1438-1447
    • Liu, X.1    Gu, X.2    Li, Z.3    Li, X.4    Li, H.5    Chang, J.6
  • 2
    • 77952317892 scopus 로고    scopus 로고
    • A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
    • Gao R, Zhang J, Cheng L, Wu X, Dong W, Yang X, et al. A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol 2010; 55: 1907-1914.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1907-1914
    • Gao, R.1    Zhang, J.2    Cheng, L.3    Wu, X.4    Dong, W.5    Yang, X.6
  • 3
    • 62249192069 scopus 로고    scopus 로고
    • Neuregulin-1/ErbB signaling: A druggable target for treating heart failure
    • Xu Y, Li X, Zhou M. Neuregulin-1/ErbB signaling: a druggable target for treating heart failure. Curr Opin Pharmacol 2009; 9: 214-219.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 214-219
    • Xu, Y.1    Li, X.2    Zhou, M.3
  • 4
    • 0028785406 scopus 로고
    • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
    • Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995; 378: 390-394.
    • (1995) Nature , vol.378 , pp. 390-394
    • Gassmann, M.1    Casagranda, F.2    Orioli, D.3    Simon, H.4    Lai, C.5    Klein, R.6
  • 5
    • 0028884413 scopus 로고
    • Requirement for neuregulin receptor erbB2 in neural and cardiac development
    • Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995; 378:394-398.
    • (1995) Nature , vol.378 , pp. 394-398
    • Lee, K.F.1    Simon, H.2    Chen, H.3    Bates, B.4    Hung, M.C.5    Hauser, C.6
  • 6
    • 0028827104 scopus 로고
    • Multiple essential functions of neuregulin in development
    • Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995; 378: 386-390.
    • (1995) Nature , vol.378 , pp. 386-390
    • Meyer, D.1    Birchmeier, C.2
  • 7
    • 0036099675 scopus 로고    scopus 로고
    • ErbB2 is essential in the prevention of dilated cardiomyopathy
    • Crone SA, Zhao YY, Fan L, Gu Y, Minamisawa S, Liu Y, et al. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 2002; 8: 459-465.
    • (2002) Nat Med , vol.8 , pp. 459-465
    • Crone, S.A.1    Zhao, Y.Y.2    Fan, L.3    Gu, Y.4    Minamisawa, S.5    Liu, Y.6
  • 8
    • 34250332921 scopus 로고    scopus 로고
    • Cardiovascular risk profile of patients with HER2/neu-positive breast cancer treated with anthracycline-taxane-containing adjuvant chemotherapy and/or trastuzumab
    • Jones LW, Haykowsky M, Peddle CJ, Joy AA, Pituskin EN, Tkachuk LM, et al. Cardiovascular risk profile of patients with HER2/neu-positive breast cancer treated with anthracycline-taxane-containing adjuvant chemotherapy and/or trastuzumab. Cancer Epidemiol Biomarkers Prev 2007; 16: 1026-1031.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1026-1031
    • Jones, L.W.1    Haykowsky, M.2    Peddle, C.J.3    Joy, A.A.4    Pituskin, E.N.5    Tkachuk, L.M.6
  • 9
    • 34548132413 scopus 로고    scopus 로고
    • Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: Implications for therapy of heart failure
    • Lemmens K, Doggen K, De Keulenaer GW. Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation 2007; 116: 954-960.
    • (2007) Circulation , vol.116 , pp. 954-960
    • Lemmens, K.1    Doggen, K.2    de Keulenaer, G.W.3
  • 10
    • 0033951542 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in heart failure: Potential for therapeutic interventions?
    • Stanley WC, Hoppel CL. Mitochondrial dysfunction in heart failure: potential for therapeutic interventions? Cardiovasc Res 2000; 45: 805-806.
    • (2000) Cardiovasc Res , vol.45 , pp. 805-806
    • Stanley, W.C.1    Hoppel, C.L.2
  • 11
    • 0034960785 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiac disease: Ischemia-reperfusion, aging, and heart failure
    • Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL. Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure. J Mol Cell Cardiol 2001; 33: 1065-1089.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1065-1089
    • Lesnefsky, E.J.1    Moghaddas, S.2    Tandler, B.3    Kerner, J.4    Hoppel, C.L.5
  • 12
    • 14744291620 scopus 로고    scopus 로고
    • Apoptosis-modulating interaction of the neuregulin/erbB pathway with anthracyclines in regulating Bcl-xS and Bcl-xL in cardiomyocytes
    • Rohrbach S, Muller-Werdan U, Werdan K, Koch S, Gellerich NF, Holtz J. Apoptosis-modulating interaction of the neuregulin/erbB pathway with anthracyclines in regulating Bcl-xS and Bcl-xL in cardiomyocytes. J Mol Cell Cardiol 2005; 38: 485-493.
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 485-493
    • Rohrbach, S.1    Muller-Werdan, U.2    Werdan, K.3    Koch, S.4    Gellerich, N.F.5    Holtz, J.6
  • 13
    • 34548394227 scopus 로고    scopus 로고
    • Neuregulins increase mitochondrial oxidative capacity and insulin sensitivity in skeletal muscle cells
    • Canto C, Pich S, Paz JC, Sanches R, Martinez V, Orpinell M, et al. Neuregulins increase mitochondrial oxidative capacity and insulin sensitivity in skeletal muscle cells. Diabetes 2007; 56: 2185-2193.
    • (2007) Diabetes , vol.56 , pp. 2185-2193
    • Canto, C.1    Pich, S.2    Paz, J.C.3    Sanches, R.4    Martinez, V.5    Orpinell, M.6
  • 14
    • 0034283407 scopus 로고    scopus 로고
    • Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: Role of oxidative stress
    • Kinugawa S, Tsutsui H, Hayashidani S, Ide T, Suematsu N, Satoh S, et al. Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress. Circ Res 2000; 87: 392-398.
    • (2000) Circ Res , vol.87 , pp. 392-398
    • Kinugawa, S.1    Tsutsui, H.2    Hayashidani, S.3    Ide, T.4    Suematsu, N.5    Satoh, S.6
  • 15
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties
    • Emaus R, Grunwald R, Lemasters JJ. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta 1986; 850: 436-448.
    • (1986) Biochim Biophys Acta , vol.850 , pp. 436-448
    • Emaus, R.1    Grunwald, R.2    Lemasters, J.J.3
  • 17
    • 0037007076 scopus 로고    scopus 로고
    • Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: Potential mechanism for trastuzumab-induced cardiotoxicity
    • Sawyer DB, Zuppinger C, Miller TA, Eppenberger HM, Suter TM. Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 2002; 105: 1551-1554.
    • (2002) Circulation , vol.105 , pp. 1551-1554
    • Sawyer, D.B.1    Zuppinger, C.2    Miller, T.A.3    Eppenberger, H.M.4    Suter, T.M.5
  • 18
    • 4043110498 scopus 로고    scopus 로고
    • Neuregulins regulate cardiac parasympathetic activity: Muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion
    • Okoshi K, Nakayama M, Yan X, Okoshi MP, Schuldt AJ, Marchionni MA, et al. Neuregulins regulate cardiac parasympathetic activity: muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion. Circulation 2004; 110: 713-717.
    • (2004) Circulation , vol.110 , pp. 713-717
    • Okoshi, K.1    Nakayama, M.2    Yan, X.3    Okoshi, M.P.4    Schuldt, A.J.5    Marchionni, M.A.6
  • 19
    • 77958086724 scopus 로고    scopus 로고
    • Cardiac functional improvement in rats with myocardial infarction by upregulating cardiac myosin light chain kinase with neuregulin
    • Gu X, Liu X, Xu D, Li X, Yan M, Qi Y, et al. Cardiac functional improvement in rats with myocardial infarction by upregulating cardiac myosin light chain kinase with neuregulin. Cardiovasc Res 2010; 88: 334-343.
    • (2010) Cardiovasc Res , vol.88 , pp. 334-343
    • Gu, X.1    Liu, X.2    Xu, D.3    Li, X.4    Yan, M.5    Qi, Y.6
  • 20
    • 78149338262 scopus 로고    scopus 로고
    • Neuregulin-1{beta}1 rapidly modulates nitric oxide synthesis and calcium handling in rat cardiomyocytes
    • Brero A, Ramella R, Fitou A, Dati C, Alloatti G, Gallo MP, et al. Neuregulin-1{beta}1 rapidly modulates nitric oxide synthesis and calcium handling in rat cardiomyocytes. Cardiovasc Res 2010; 88: 443-452.
    • (2010) Cardiovasc Res , vol.88 , pp. 443-452
    • Brero, A.1    Ramella, R.2    Fitou, A.3    Dati, C.4    Alloatti, G.5    Gallo, M.P.6
  • 21
    • 0032168434 scopus 로고    scopus 로고
    • Abnormal mitochondrial function in myocardium of dogs with chronic heart failure
    • Sharov VG, Goussev A, Lesch M, Goldstein S, Sabbah HN. Abnormal mitochondrial function in myocardium of dogs with chronic heart failure. J Mol Cell Cardiol 1998; 30: 1757-1762.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 1757-1762
    • Sharov, V.G.1    Goussev, A.2    Lesch, M.3    Goldstein, S.4    Sabbah, H.N.5
  • 22
    • 9644310269 scopus 로고    scopus 로고
    • Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: Implications for herceptin-induced cardiomyopathy
    • Grazette LP, Boecker W, Matsui T, Semigran M, Force TL, Hajjar RJ, et al. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. J Am Coll Cardiol 2004; 44: 2231-2238.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 2231-2238
    • Grazette, L.P.1    Boecker, W.2    Matsui, T.3    Semigran, M.4    Force, T.L.5    Hajjar, R.J.6
  • 23
    • 59049093631 scopus 로고    scopus 로고
    • Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways
    • Gordon LI, Burke MA, Singh AT, Prachand S, Lieberman ED, Sun L, et al. Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways. J Biol Chem 2009; 284: 2080-2087.
    • (2009) J Biol Chem , vol.284 , pp. 2080-2087
    • Gordon, L.I.1    Burke, M.A.2    Singh, A.T.3    Prachand, S.4    Lieberman, E.D.5    Sun, L.6
  • 24
    • 0032562770 scopus 로고    scopus 로고
    • Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
    • Zhao YY, Sawyer DR, Baliga RR, Opel DJ, Han X, Marchionni MA, et al. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 1998; 273: 10261-10269.
    • (1998) J Biol Chem , vol.273 , pp. 10261-10269
    • Zhao, Y.Y.1    Sawyer, D.R.2    Baliga, R.R.3    Opel, D.J.4    Han, X.5    Marchionni, M.A.6
  • 25
    • 0344924865 scopus 로고    scopus 로고
    • Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt
    • Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, et al. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J Mol Cell Cardiol 2003; 35: 1473-1479.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 1473-1479
    • Fukazawa, R.1    Miller, T.A.2    Kuramochi, Y.3    Frantz, S.4    Kim, Y.D.5    Marchionni, M.A.6
  • 26
    • 10944236872 scopus 로고    scopus 로고
    • Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling
    • Kuramochi Y, Cote GM, Guo X, Lebrasseur NK, Cui L, Liao R, et al. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling. J Biol Chem 2004; 279: 51141-51147.
    • (2004) J Biol Chem , vol.279 , pp. 51141-51147
    • Kuramochi, Y.1    Cote, G.M.2    Guo, X.3    Lebrasseur, N.K.4    Cui, L.5    Liao, R.6
  • 27
    • 0742305448 scopus 로고    scopus 로고
    • Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta
    • Kuramochi Y, Lim CC, Guo X, Colucci WS, Liao R, Sawyer DB. Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta. Am J Physiol Cell Physiol 2004; 286: C222-C229.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Kuramochi, Y.1    Lim, C.C.2    Guo, X.3    Colucci, W.S.4    Liao, R.5    Sawyer, D.B.6
  • 28
    • 33750915424 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress, DNA damage, and heart failure
    • Tsutsui H, Ide T, Kinugawa S. Mitochondrial oxidative stress, DNA damage, and heart failure. Antioxid Redox Signal 2006; 8: 1737-1744.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1737-1744
    • Tsutsui, H.1    Ide, T.2    Kinugawa, S.3
  • 29
    • 0035896205 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction
    • Ide T, Tsutsui H, Hayashidani S, Kang D, Suematsu N, Nakamura K, et al. Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction. Circ Res 2001; 88: 529-535.
    • (2001) Circ Res , vol.88 , pp. 529-535
    • Ide, T.1    Tsutsui, H.2    Hayashidani, S.3    Kang, D.4    Suematsu, N.5    Nakamura, K.6
  • 30
    • 0028356959 scopus 로고
    • Antioxidant changes in hypertrophied and failing guinea pig hearts
    • Dhalla AK, Singal PK. Antioxidant changes in hypertrophied and failing guinea pig hearts. Am J Physiol 1994; 266: H1280-H1285.
    • (1994) Am J Physiol , vol.266
    • Dhalla, A.K.1    Singal, P.K.2
  • 31
    • 0030754792 scopus 로고    scopus 로고
    • Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction
    • Hill MF, Singal PK. Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction. Circulation 1997; 96: 2414-2420.
    • (1997) Circulation , vol.96 , pp. 2414-2420
    • Hill, M.F.1    Singal, P.K.2
  • 32
    • 21644470216 scopus 로고    scopus 로고
    • Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta
    • Giraud MN, Fluck M, Zuppinger C, Suter TM. Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta. J Appl Physiol 2005; 99: 313-322.
    • (2005) J Appl Physiol , vol.99 , pp. 313-322
    • Giraud, M.N.1    Fluck, M.2    Zuppinger, C.3    Suter, T.M.4
  • 33
    • 0000350066 scopus 로고    scopus 로고
    • Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA
    • De la Asuncion JG, Millan A, Pla R, Bruseghini L, Esteras A, Pallardo FV, et al. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. Faseb J 1996; 10: 333-338.
    • (1996) Faseb J , vol.10 , pp. 333-338
    • de la Asuncion, J.G.1    Millan, A.2    Pla, R.3    Bruseghini, L.4    Esteras, A.5    Pallardo, F.V.6
  • 34
    • 0031984178 scopus 로고    scopus 로고
    • A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress
    • Sastre J, Millan A, Garcia de la Asuncion J, Pla R, Juan G, Pallardo, et al. A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress. Free Radic Biol Med 1998; 24: 298-304.
    • (1998) Free Radic Biol Med , vol.24 , pp. 298-304
    • Sastre, J.1    Millan, A.2    Garcia de la Asuncion, J.3    Pla, R.4    Juan, G.5    Pallardo6
  • 36
    • 0037423550 scopus 로고    scopus 로고
    • β-Adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway
    • Remondino A, Kwon SH, Communal C, Pimentel DR, Sawyer DB, Singh K, et al. β-Adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. Circ Res 2003; 92: 136-138.
    • (2003) Circ Res , vol.92 , pp. 136-138
    • Remondino, A.1    Kwon, S.H.2    Communal, C.3    Pimentel, D.R.4    Sawyer, D.B.5    Singh, K.6
  • 37
    • 41949104144 scopus 로고    scopus 로고
    • Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: Linking mitochondrial oxidative damage and vascular endothelial dysfunction
    • Doughan AK, Harrison DG, Dikalov SI. Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res 2008; 102: 488-496.
    • (2008) Circ Res , vol.102 , pp. 488-496
    • Doughan, A.K.1    Harrison, D.G.2    Dikalov, S.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.