Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration

Journal of Controlled Release

Volumn 173, Issue 1, 2014, Pages 132-139

  Formiga, Fabio R ^a   Pelacho, Beatriz ^b   Garbayo, Elisa ^a   Imbuluzqueta, Izaskun ^a   Díaz Herráez, Paula ^a   Abizanda, Gloria ^b   Gavira, Juan J ^b   Simón Yarza, Teresa ^a   Albiasu, Edurne ^b   Tamayo, Esther ^a   Prósper, Felipe ^b   Blanco Prieto, Maria J ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Cardiac repair; FGF1; Myocardial infarction; NRG1; PLGA microparticles

Indexed keywords

CARDIAC REPAIR; FGF1; MYOCARDIAL INFARCTION; NRG1; PLGA MICROPARTICLES;

CELL DEATH; EMULSIFICATION; PROTEINS; RATS; REPAIR; STEM CELLS; TISSUE;

HEART;

FIBROBLAST GROWTH FACTOR 1; NANOPARTICLE; NEU DIFFERENTIATION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIODEGRADABILITY; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; EMULSION; EVAPORATION; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE REVASCULARIZATION; IN VITRO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MICROENCAPSULATION; MUSCLE REGENERATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN STABILITY; RAT; STATISTICAL SIGNIFICANCE; STEM CELL;

CARDIAC REPAIR; FGF1; MYOCARDIAL INFARCTION; NRG1; PLGA MICROPARTICLES;

ANIMALS; DELAYED-ACTION PREPARATIONS; FEMALE; FIBROBLAST GROWTH FACTOR 1; HEART; HUMANS; MYOCARDIAL INFARCTION; MYOCARDIUM; NEUREGULIN-1; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; REGENERATION;

EID: 84888106647     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.10.034     Document Type: Article

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