CRL3IBTK regulates the tumor suppressor Pdcd4 through ubiquitylation coupled to proteasomal degradation

Journal of Biological Chemistry

Volumn 290, Issue 22, 2015, Pages 13958-13971

  Pisano, Antonio ^a   Ceglia, Simona ^a   Palmieri, Camillo ^a   Vecchio, Eleonora ^a   Fiume, Giuseppe ^a   De Laurentiis, Annamaria ^a   Mimmi, Selena ^a   Falcone, Cristina ^a   Iaccino, Enrico ^a   Scialdone, Annarita ^a   Pontoriero, Marilena ^a   Masci, Francesca Fasanella ^a   Valea, Rosanna ^a   Krishnan, Shibu ^a   Gaspari, Marco ^a   Cuda, Giovanni ^a   Scala, Giuseppe ^a   Quinto, Ileana ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BODY FLUIDS; CELL PROLIFERATION; MOBILE SECURITY;

BRUTON'S TYROSINE KINASE; CELLULAR PATHWAY; INDUCED DEGRADATION; PROTEASOMAL DEGRADATION; REGULATORY MECHANISM; TUMOR SUPPRESSORS; UBIQUITIN LIGASES; UBIQUITYLATION;

TUMORS;

BRUTON TYROSINE KINASE; BRUTON TYROSINE KINASE ALPHA; CULLIN; CULLIN 3; PROGRAMMED CELL DEATH 4; PROTEIN BCL XL; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; GLUTATHIONE; IBTK PROTEIN, HUMAN; MESSENGER RNA; PDCD4 PROTEIN, HUMAN; PROTEASOME; PROTEIN BINDING; RNA BINDING PROTEIN; SMALL INTERFERING RNA; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

5' UNTRANSLATED REGION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RNA INTERFERENCE; RNA TRANSLATION; UBIQUITINATION; ANIMAL; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HOMEOSTASIS; HUMAN; LENTIVIRINAE; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CARRIER PROTEINS; GLUTATHIONE; HEK293 CELLS; HELA CELLS; HOMEOSTASIS; HUMANS; LENTIVIRUS; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84930663617     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.634535     Document Type: Article

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