Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool

PLoS Biology

Volumn 13, Issue 5, 2015, Pages

  van Wyk, Michiel ^a   Pielecka Fortuna, Justyna ^b   Löwel, Siegrid ^b   Kleinlogel, Sonja ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOPSIN; METABOTROPIC RECEPTOR 6; OPTO METABOTROPIC RECEPTOR 6; UNCLASSIFIED DRUG; METABOTROPIC RECEPTOR; SCOTOPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLINDNESS; CONTROLLED STUDY; EMBRYO; GENE THERAPY; HUMAN; HUMAN CELL; HUMAN TISSUE; ILLUMINATION; MOLECULAR CLONING; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; OPTOGENETICS; PROTEIN EXPRESSION; RETINA BIPOLAR GANGLION CELL; STRIATE CORTEX; TREATMENT RESPONSE; VISUAL STIMULATION; VISUAL SYSTEM FUNCTION; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL PATCH CLAMP; ANIMAL; C3H MOUSE; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; PROCEDURES; TRANSGENIC MOUSE; VISION;

ANIMALS; BLINDNESS; GENETIC THERAPY; HEK293 CELLS; HUMANS; MICE, INBRED C3H; MICE, TRANSGENIC; OPTOGENETICS; RECEPTORS, METABOTROPIC GLUTAMATE; RETINAL BIPOLAR CELLS; ROD OPSINS; VISION, OCULAR; VISUAL PERCEPTION;

EID: 84930641713     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002143     Document Type: Article

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