Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa

Molecular Therapy

Volumn 19, Issue 2, 2011, Pages 234-242

  Pang, Ji Jing ^a,b   Dai, Xufeng ^a,b   Boye, Shannon E ^b   Barone, Ilaria ^c   Boye, Sanford L ^b   Mao, Song ^b   Everhart, Drew ^d   Dinculescu, Astra ^b   Liu, Li ^b   Umino, Yumiko ^d   Lei, Bo ^e   Chang, Bo ^f   Barlow, Robert ^d   Strettoi, Enrica ^c   Hauswirth, William W ^b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c CNR   (Italy)

^d SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^e THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^f JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP PHOSPHODIESTERASE; PARVOVIRUS VECTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DARK ADAPTATION; DRUG EFFICACY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; LIGHT ADAPTATION; MOUSE; NIGHT VISION; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; RETINITIS PIGMENTOSA; SEROTYPE; TREATMENT DURATION; TREATMENT RESPONSE; VIRAL GENE DELIVERY SYSTEM; VISUAL ACUITY;

ANIMALIA; MIRIDAE; MUS;

EID: 79551620165     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.273     Document Type: Article

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